GlycanHub Podcast – Détails, épisodes et analyse

Is the future of medicine sweetened by the study of glycans? As GlycanHub rounds off its season, we've brought back the insights of 11 eminent scientists spanning from neuroscience to nanotechnology. Each guest delves into their vision of how glycans could shape medical advancements in their respective fields. Join Rina, our host, for a grand finale that paints a holistic picture of the promising horizon glycobiology is steering us towards.

Answers to the question: What role do you think glycans will play in the future of medicine relevant to your area of study? 

• Salome Pinho [01:21]  
• Olga Zaytseva [03:04]     
• Peter Joshi [03:51]    
• Hudson Freeze [05:11]   
• Samia Mora [06:11]      
• Anna Halama and Karsten Suhre [08:09]      
• Ronald Schnaar [12:03]      
• Gordon Lauc [14:49]    
• Louise Newson [17:35]      
• Vered Padler-Karavani [18:47]

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Please be advised that this show is for information only and should not be considered as a replacement or equal to medical advice. 

Could your steak dinner be tricking your immune system? In this episode we shed light on the connection between specific foods and colorectal cancer. Explore xeno-autoantigens, grasp the nuances of immunotherapy, and question the reliability of animal-derived heart valves. Vered Padler-Karavani is the principal investigator in the Department of Cell Research and Immunology at Tel Aviv University. Her research combines glycobiology, immunology, bio-nanotechnology, cancer research and xenotransplantation. Tune in to uncover the hidden connections between glycans, our diet, and the potential health repercussions.

We discuss: 

• Why study Glycobiology [01:35]
• Xeno-autoantigens & Xenosialitis [03:16]
• Where Does Neu5Gc Accumulate? [06:33]
• Red Meat & Colorectal Cancer [10:28]
• Tumor-associated Carbohydrate Antigens [11:54]
• Immunotherapy: Potential & Limitations [13:22]
• Animal-derived Heart Valves: Safety & Efficacy [20:02]
• Navigating Safety Regulations for Biologic Therapies [31:27] 
• Neu5Gc in Foods: The Gcemic Index [34:14]
• Does Prof. Vered Padler-Karavani Still Eat Red Meat? [37:23]
• Neu5Gc as Biomarkers [38:08]

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Please be advised that this show is for information only and should not be considered as a replacement or equal to medical advice. 

Glycans have a great capacity to fine-tune the inflammatory response and often determine how successfully the immune system distinguishes between friend and foe. While cancer cells build a glycan shield to hide from immune surveillance, pathogens can mimic our glycans in order to evade immune detection and perpetuate infection. Salomé Pinho is the Immunology, Cancer and GlycoMedicine Group leader at the Institute for Research and Innovation in Health at the University of Porto, her research focuses on cancer and inflammatory conditions. Listen in as she introduces us to the intricacies of immune regulation and the potential of glycans as diagnostic and prognostic biomarkers as well as immunotherapeutic targets. 

We Discuss: 

• The role of glycans in immunological tolerance [4:51] 
• Why has glycobiology been neglected for so long? [10:28]
• Cancer and immune tolerance [12:08] 
• Glycans as cancer biomarkers and immunotherapeutic targets [20:00] 
• Glycan mimicry in autoimmune diseases [23:48] 
• Glycans as biomarkers of inflammatory bowel disease (IBD) [27:49] 
• GlycanSwitch Project [35:33] 

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Please be advised that this show is for information only and should not be considered as a replacement or equal to medical advice. 

Is it enough to conduct medical research only on white men? Why are women more affected by autoimmune diseases? Do menopause and pregnancy trigger different ailments? Is there such a thing as a male and a female hormone?
 
In this episode of The Age of You - a sweet secret to longevity, we discuss male-centric medicine and the effects created by the exclusion of women in medical research.
 
Our guests are DR Alka Patel, a TEDx speaker, GP, lifestyle doctor, longevity coach, author, podcaster, the founder of Lifestyle First, a platform that helps people change their lifestyles for the better and DR Julia Jurić - a Senior Researcher at Genos Glycoscience Laboratory.
 
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You can find our guest, DR Alka Patel, via the links below -
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Social:
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Please be advised that this video is for information only and should not be considered as a replacement or equal to medica

Menopause is no laughing matter, but having humour about it might be the key to breaking down the stigma. 

In order to celebrate World Menopause Day, we’re bringing you an uplifting interview with Suzzane Parkes - a person near and dear to all of us in GlycanAge. Suzanne is a consultant that spent her career in the fitness industry and has always prioritized a holistic approach to her health. 

Suzanne is passionate about sharing her menopause journey in order to prevent future generations from suffering the way she has. Her vulnerability has helped us prepare an amazing episode which will answer the most common questions we receive about menopause. 

The episode will cover 

• Menopause symptoms
• How men can support their partners through menopause
• The process of getting diagnosed with menopause
• The shame associated with menopause
• HRT and alternative methods of alleviating symptoms 
• How GlycanAge can help monitor the changes caused by menopause

As always, if you have any questions, you can leave them as comments on our social media which are listed below. 

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Find out more information about GlycanAge on our website
For more information on managing your menopause, check out the Balance app

Please be advised that this video is for information only and should not be considered as a replacement or equal to medical advice.

Despite the buzz around novel cancer therapies, the harsh reality is that most only extend life expectancy by a few months. Dr Azra Raza, a Professor of Medicine, and the Director of the MDS Centre at Columbia University, has a different approach. Azra argues that the key to defeating cancer lies in early detection, and she has dedicated over 35 years of her career to collecting samples and researching myelodysplastic syndromes (MDS) with the goal of catching cancer at its earliest stage. Listen in as she discusses her ground-breaking work and her belief that we are entering a new cancer parading. Dr Raza is leading the charge with a coalition of 8 leading institutions in the USA. 

We Discuss: 

• Azra’s first patient [5:56] 
• The impact of losing her husband to cancer on Azra as an oncologist [9:49] 
• Ageing is the most potent carcinogen [13:34] 
•  Azra’s new cancer model [17:06] 
•  Azra’s revolution – coalition of 8 institutions [24:45] 
• Mice are the real elephants in the room [30:51] 
• Who pays the cost of cancer treatment? [39:21] 
• Azra’s tissue repository – 35 years in the making [43:20] 
• Why is early detection the way forward? [48:42] 
• In search for the giant cell [53:34] 
• The First Cell Centre [1:00:52] 
• Advice for young scientists and clinicians [1:07:16] 
•  Azra’s final message [1:11:42] 

You can find our guest, Dr Azra Raza, via these links:
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Please be advised that this show is for information only and should not be considered as a replacement or equal to medical advice. 

Why do women age faster during menopause? Should menopause be rebranded as a hormone deficiency?  Is it ever too late to start HRT? Listen to this episode to find out the answers to these questions and many more!

 Meet the guests:
Doctor Louise Newson is the Founder of Newson Health Menopause & Wellbeing Centre as well as Balance App and The Menopause Charity.  She’s a renowned menopause specialist and is dedicated to helping women of all ages understand that menopause doesn’t have to be a terrible experience. If you’re interested in learning more about her work and tips for anyone in perimenopause or menopause, you can find it in her book - Preparing for Perimenopause and Menopause.

Tim Spector is a professor of Genetic Epidemiology at King's College London and the scientific cofounder of ZOE - a health science company committed to helping people understand how their bodies respond to food. Professor Spector wrote two insightful books grounded in latest research that dive deeper into nutrition and the myths of dieting - Spoon Fed and The Diet Myth.

Gordan Lauc is the leading scientist in the field of glycobiology and the founder of Genos, the world’s largest glycan analysis facility in the world.

All of our listeners are invited to use the code WOMENSDAY at the checkout page and get a 20% discount on a GlycanAge test.

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t’s not often you get to listen to inspirational yet grounded people. However, today we bring you just that. Meet Anastasis Tzanis — A yoga and breathing instructor, and a nutritional therapist. He shared his struggles with IBS, the effects of yoga, and his experience with GlycanAge. Find out why he doesn’t believe in the one-solution-fits-all approach and why he’s not a fan of restrictive diets. As he and Rina discuss trends in the alternative health industry, Anastasis shares his tips on how to spot the right people to work with. 

 Find out more about Anastasis via the following links:
Breathing for Yoga course:  https://oxygenadvantage.com/breathing-for-yoga-online-course/
Website: www.atzanis.com
Linkedin:  https://www.linkedin.com/in/anastasistzanis/

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Find out more information about GlycanAge on our website glycanage.com

Dear listener, are you interested in learning how to live healthier and take advantage of the latest scientific research? If the answer is yes, you’ll love our first episode in which we dive into understanding longevity.

 Tune in as our host Rina interviews Professor Gordan Lauc on the importance of glycans and how these sugars will shape the future of medicine. Other topics we discuss in the episode are - chronic illness, interesting research into the best diet, modern medicine and more. 

Find out more information about GlycanAge on our website https://glycanage.com/
Watch the video recording of this podcast on YouTube. 
Engage with us on social media: 

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 Please be advised that this video is for information only and should not be considered as a replacement or equal to medical advice. 

Does menopause hold implications beyond reproductive health? This episode reveals that the shift in hormonal balance affects inflammatory patterns, mediated by complex carbohydrates called glycans. We unravel the overlooked role of perimenopause in chronic disease onset and debunk common myths. Exploring hormone replacement therapy, we discuss its wider health impact, beyond mere symptom management. Louise Newson, a distinguished GP and Menopause Specialist, is the founder of the Balance App, The Menopause Charity, and the Newson Health Menopause Society. An active member of the UK Government Menopause Taskforce, she continually works to elevate menopause understanding and care.

Listen in as we discuss the potential of glycans as biomarkers for menopause, surpassing existing diagnostic tests in their predictive capacity.

We discuss: 

• Menopause Specialisation: Why Choose It? [02:11]
• Menopause: Myths vs. Facts [04:12]
• What Exactly Is Menopause? [05:33]
• Testosterone's Role in Female Health [08:04]
• Sex Hormones and Immune Regulation [09:18]
• Menopause and the Rise of Chronic Illness [12:36]
• Viewing Menopause as a Hormone Deficiency [15:22]
• Menopause and Metabolic Syndrome [16:57]
• Menopause and the Gut Microbiome [18:20]
• Oestrogen's Role in the Cardiovascular System [24:03]
• Is Perimenopause Contributing to Chronic Disease? [26:59]
• Limitations of Current Menopause Tests [30:53]
• Introducing the Balance App [32:00]
• Glycan-Based Menopause Tests [34:05]
• Addressing the Lack of Menopause Education in Medicine [35:36]
• Common Questions About Hormone Replacement Therapy [38:50]
• A Look at the Newson Clinic [41:26]

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Please be advised that this show is for information only and should not be considered as a replacement or equal to medical advice.