Genomics Now – Détails, épisodes et analyse

Welcome to Genomics Now, a podcast series where you can learn how genomics is developing in England's NHS. This podcast series is recorded in 2024 and is part of the North Thames Genomic Medicine Service's (NTGMS) educational toolkit.

In each bite-sized episode, we explore what is changing in genomics. We answer the questions on genomics we've been asked by different healthcare professionals, discuss the ways genomics may impact various healthcare roles, and how genomics can be used to improve patient care successfully.

In this final episode of the NTGMS liquid biopsy podcast series, Dr. Shazia Mahamdallie welcomes Gini as her co-host, a Trustee for EGFR Positive UK. Today, they are joined by Mark and Janet who have lived-experience of biopsy testing for lung cancer.

Mark was diagnosed 12 years ago with stage two lung cancer, today he shares his journey from initial symptoms to the groundbreaking liquid biopsy that revealed a genetic change leading to successful targeted treatment.

Janet recounts her recent diagnosis and the symptoms that led her to participate in the NHS's lung cancer pilot for liquid biopsy testing, and that led to her swift treatment turnaround.

Join us as we explore the critical role of liquid biopsies in lung cancer treatment and the profound impact this test the NHS is piloting can have on patients' lives.

For more resources and updates on genomic-based clinical developments and research, visit the North Thames Genomic Medicine Service website. If you enjoyed this episode, share your thoughts and spread the word on social media by tagging the North Thames Genomic Medicine Service.

Welcome to Genomics Now, a podcast series where you can learn how genomics is developing in England's NHS. This podcast series is recorded in 2024 and is part of the North Thames Genomic Medicine Services Educational Toolkit. In each bite-sized episode, we explore what is changing in genomics. We answer the questions on genomics we've been asked by different healthcare professionals, discuss how genomics may impact various healthcare roles, and examine how genomics can be used to successfully improve patient care.

In today’s episode, we delve into the clinician's perspective on NHS England's liquid biopsy circulating tumour DNA pilot. Hosted by Dr. Shazia Mahamdallie, this episode features Dr. Alistair Greystoke, a Professor of Oncology, and Dr. William Ricketts, a Consultant chest physician. They discuss the integration and impact of liquid biopsy testing on lung cancer diagnosis and patient care.

Join us and learn about the practical tips, patient benefits, and logistical challenges encountered during the pilot, as well as the promising future applications of liquid biopsy testing in diagnostics and treatment monitoring. Tune in for an engaging and informative discussion that highlights the potential of genomics to change how we deliver healthcare.

For more resources and updates on genomic-based clinical developments and research, visit the North Thames Genomic Medicine Service website. If you enjoyed this episode, share your thoughts and spread the word on social media by tagging the North Thames Genomic Medicine Service.

Speakers: Dr. Dahlia Hopmeier and Dr. Helen Grote

This episode addresses the various implications that genomic test results may have for a patient, as well as their family members. It focuses on the challenges that may arise with regards to sharing of information, and the ways in which families can be supported throughout this process.

Recorded in June 2021

Speakers: Dr. Dahlia Hopmeier and Dr. Rhiannon Melis

This episode explores the various ways in which fetal DNA can be examined, including fetal exome sequencing. The clinical utility and how this fits into NHS testing pathways is also discussed.

Recorded in June 2021

Speakers: Dr. Dahlia Hopmeier and Dagmar Tapon

This episode explains the concept of non-invasive prenatal testing (NIPT) and the roll-out of this technique as an additional testing option in the NHS.

Recorded in June 2021

Speakers: Dr. Dahlia Hopmeier and Dr. Angela Brady

In this episode the role of genomics in rare disease is discussed, and explanations of genomic variants and how they are identified and interpreted are given.

Recorded in June 2021

Speakers: Dr. Dahlia Hopmeier and Dr. Angela Brady

This episode gives a brief overview of the role of genomics in cancer and explains key concepts including familial cancer syndromes and diagnostic versus predictive gene testing.

Recorded in June 2021

Speakers: Dr. Dahlia Hopmeier and Dr. Anwar Khan

In this episode the concept of pharmacogenomics is explained along with examples of pharmacogenomics already in use by the NHS. The role of pharmacogenomics in general practice and predictions for the future are also discussed.

Recorded in May 2021

Speakers: Dr. Dahlia Hopmeier and Dr. Anwar Khan

This episode focuses on simple explanations on genomics for patients to enable primary care practitioners to discuss genomics in their daily practice.

Recorded in May 2021.

Speakers: Dr. Dahlia Hopmeier and Dr. Anwar Khan

This episode explains the variability of direct-to-consumer tests and the potential limitations and risks. The role of the GP in interpreting results from these tests is explored, with reference to the Royal College of General Practitioner’s position statement.

Recorded in May 2021