Feel Better. Live Free. | Healthy Weight Loss & Wellness for Midlife Women – Détails, épisodes et analyse

If you've been told that the weight gain, the exhaustion, the brain fog, and the joint pain are just "part of having an autoimmune disease" — this episode is for you.

For decades, that's exactly what I was told. I was diagnosed with Hashimoto's, Raynaud's, and lupus in my teens and twenties, and I spent most of my adult life feeling sick, exhausted, and in pain. I hit 288 pounds. I tried every diet. I lost weight, gained it back, and blamed myself every single time. And every time I went to the doctor, the script was the same: "I'm not sure exactly what's going on. It's probably autoimmune related. Also — it would probably help if you lost some weight."

Like that was a treatment plan.

In this episode, I'm pulling back the curtain on the real reason it's so much harder for women with autoimmune conditions to lose weight — and it has nothing to do with willpower. There's actually a clear hormonal cascade going on inside your body, and once you understand it, the whole picture changes.

We're covering:

• Why autoimmune disease creates the chronic inflammation that drives insulin resistance
• How insulin resistance literally locks fat in your cells (and why "eating less" can't fix it)
• The thyroid piece your doctor probably isn't testing for — even with Hashimoto's
• The role medications like steroids play in weight gain and bone density
• Why a doctor's casual "you should lose weight" advice isn't a plan — it's a brush-off
• Three specific things you can do this week to start healing

I'm sharing my own story, too — including the moment my chronic migraines and cluster headaches almost completely disappeared after years of suffering. That was the moment I knew this wasn't a diet. This was healing.

I want to be clear: I'm not telling you that food cured my autoimmune diseases. I still have Hashimoto's, Raynaud's, and lupus. But my body finally got what it needed — and the difference was profound. Eight years later, I've maintained over 100 pounds of weight loss, my energy is steady, and I'm finally living the life I thought I'd lost.

If you've been working harder than anyone you know and getting nowhere — please, listen to this one.

Ready to start healing your metabolism? Get our free guide at Thinlicious.com/happy.

Episode Summary

Women have up to 70-80% lower creatine stores than men — and most of us have never been told that. In this episode Lisa digs into what that means for your brain, sleep, mood, muscles, and energy, and why creatine may be one of the most underreported tools in women's health right now.

What You'll Learn

• What creatine actually is and why it matters beyond the gym
• Why women have lower creatine stores — and why that gap widens in perimenopause
• How creatine supports brain energy (ATP) and what happens when levels run low
• The research on creatine and memory, processing speed, and mental clarity
• Why creatine may reduce depression symptoms — more so in women than men
• Creatine and sleep: the adenosine mechanism, the 2024 women's RCT, and the 2025 perimenopause findings
• The University of Kansas Alzheimer's pilot study
• Creatine + resistance training for muscle and bone health over 40
• How much to take: 5g for general health vs. 10g for brain-specific benefits

Start Here

Ready to heal your metabolism? thinlicious.com/happy

Studies Referenced

Cognitive Function & Memory

Xu et al. (2024) — Creatine & Cognitive Function: Systematic Review & Meta-Analysis. Frontiers in Nutrition.

Depression in Women

Lyoo et al. (2012) — Creatine Augmentation for SSRI in Women With Major Depression. American Journal of Psychiatry.

Systematic Review & Meta-Analysis: Creatine for Depression (2025). British Journal of Nutrition.

Sleep

Dworak et al. (2017) — Creatine Reduces Sleep Need & Homeostatic Sleep Pressure in Rats. Journal of Sleep Research.

Aguiar Bonfim Cruz et al. (2024) — Creatine Improves Sleep in Naturally Menstruating Females. Nutrients.

Gordji-Nejad et al. (2024) — Single Dose Creatine Improves Cognition During Sleep Deprivation. Scientific Reports.

Hall et al. (2025) — Creatine + Resistance Training in Peri/Postmenopausal Women: Sleep, Cognition, Strength. JISSN.

Alzheimer's Disease

Smith et al. (2025) — Creatine Monohydrate Pilot in Alzheimer's: Brain Creatine & Cognition. Alzheimer's & Dementia.

Brain Dosing: The Case for 10g

Dechent et al. (1999) — Creatine Increases Brain Creatine by 8.7% in Human Neuroimaging Study. American Journal of Physiology.

Candow et al. — Higher Creatine Doses for Brain Bioenergetics. Journal of Psychiatry and Brain Science.

Dr. Rhonda Patrick on 10g brain dosing (@foundmyfitness)

Medical Disclaimer: For educational purposes only. Not medical advice. Always consult your doctor before starting any new supplement.

If you’re trying to get healthy, lose weight, fix your hormones, or heal your gut—but you’re still buying meat from the grocery store—you might be missing the most important piece of the puzzle.

Because what you eat matters—but what your food ate (and the soil it was grown in)? 

Believe it or not, that matters even more.

Today’s guest is going to explain exactly why—and once you hear it, you’ll never look at your plate the same way again.

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If you’ve ever had a moment where you walked into a room and forgot why you were there, or you couldn’t find your car keys for the millionth time, or you just couldn’t quite remember that person’s name that you just met, then you know how frustrating it can be to feel like your brain is turning to mush.

And the reality is, you’re not alone. In fact, cognitive decline is a huge issue for many adults, and it only gets worse as we get older. It’s estimated that by the time we reach our mid-60s, one in every nine people will be diagnosed with some form of dementia, and by the time we reach our 80s, that number jumps to one in three.

But here’s the good news—it doesn’t have to be this way. There are actually some really simple steps you can take starting TODAY to improve your brain health and reduce your risk of cognitive decline in the future. And in this episode, I’m going to be breaking down exactly what those steps are.

Get our FREE guide to finally fix your metabolism!

Losing weight & getting healthy is never easy, but lately you might feel like it’s suddenly become impossible.

Our Flip the Switch guide will help you clearly understand what’s been going on, as well as exactly what you can do to get your metabolism working again so that you can look and feel your best—it’s easier and more simple than you think! Get it HERE.

If you grew up in the 80's and 90's like me, then you've probably been conditioned to believe that FAT is BAD.

And honestly, I think that's a hard bias to overcome.

Because for YEARS, we were told that fat was bad for us, that it clogged our arteries and made us gain weight, that it was the root cause of all of our health problems. 

And as a result, food manufacturers went out of their way to create low-fat and fat-free versions of all of our favorite foods, and we all went along with it, believing that we were making healthier choices.

But here's the thing: it turns out that was all a bunch of nonsense. 

In fact, if you've been listening to this podcast for any amount of time, then you've probably heard me talk about why fat is actually GOOD for you. 

You've heard me talk about how it's our body's preferred source of fuel, and it's what helps to metabolize and stabilize your hormones, and how eating more healthy fats and fewer processed carbohydrates can help you lose weight and improve your overall health in SO many ways.

But if that's true, then which fats ARE good for you?

How do you know which ones to include in your diet and which ones to avoid? And how do you know which fats are actually going to help balance your hormones the way you need them to?

That's exactly what we're going to be diving into in today's episode—the ultimate guide to hormone-friendly healthy fats, and what you need to know about how they affect your health.

Get our FREE guide to finally fix your metabolism!

Losing weight & getting healthy is never easy, but lately you might feel like it’s suddenly become impossible.

Our Flip the Switch guide will help you clearly understand what’s been going on, as well as exactly what you can do to get your metabolism working again so that you can look and feel your best—it’s easier and more simple than you think! Get it HERE.

Today is the day! 

After many months of blood, sweat & tears—along with a lot of collaboration with you, our Health Rebel community—I’m SO excited to finally be able to tell you that our brand new Thinlicious App is ready for you.

And I’m not even kidding when I tell you this is about to become the go-to resource for any woman over 40 who is serious about losing weight and transforming your health.

Get our FREE guide to finally fix your metabolism!

Losing weight & getting healthy is never easy, but lately you might feel like it’s suddenly become impossible.

Our Flip the Switch guide will help you clearly understand what’s been going on, as well as exactly what you can do to get your metabolism working again so that you can look and feel your best—it’s easier and more simple than you think! Get it HERE.

So here's a fun fact for you: when it comes to losing weight, your body doesn't actually care about your goals.

It doesn't care what size jeans you want to fit into, or what the number on the scale says, or whether or not you're finally ready to wear a bikini this summer.

But your body does have a goal.

And that goal, more than anything else, is to SURVIVE.

Your body's primary purpose is SELF-PRESERVATION.

To keep your heart pumping and your brain working and your blood flowing through your veins.

And that might not seem all that relevant, but that's actually why, for so many of us, losing weight feels like an uphill battle. It's not because we're weak, or because we don't have enough willpower, or because we're just not trying hard enough.

It's because our bodies are literally working against us.

They're fighting to hold onto every last ounce of fat, and they're driving us to consume more and more calories to keep us alive.

We're basically fighting an invisible war against our own biology, and most of us don't even realize it.

So today, we're going to do something about that.

We're going to dive deep into the science of weight loss so that you can fully understand what's REALLY happening in your body when you try to lose weight, which will probably ALSO help you understand why so much of what you've tried—and all the expert advice you've always heard—hasn't worked.

It's going to be fun, and I think really eye-opening. So get ready. Because once you see the light, you can't unsee it.
Get our FREE guide to finally fix your metabolism!

Losing weight & getting healthy is never easy, but lately you might feel like it’s suddenly become impossible.

Our Flip the Switch guide will help you clearly understand what’s been going on, as well as exactly what you can do to get your metabolism working again so that you can look and feel your best—it’s easier and more simple than you think! Get it HERE.

There's nothing more frustrating than feeling like you're doing all the right things to lose weight and get healthy, only to see the scale just not budge.

Believe me, I get it.

After all, it's one thing to KNOW you're not really eating as well as you could be, or that you blew it over the weekend, or that you're just not trying all that hard.

But it's a whole different level of frustration when you actually ARE putting in the effort, and yet the scale doesn't reflect it.

And while on some level we probably know that getting healthy for life isn't JUST about the number on the scale, it's still tends to be the thing we focus on—the number that we use to measure whether we're actually making progress toward our goal.

 So why is it that some of us seem to have SO much success so quickly, while others have to fight for every single pound? 

And is there anything you can do to make it easier?

That's exactly what we're going to talk about in today's episode—the big reasons you may be struggling to lose weight, even when you're doing everything right, and a few things you can try.

Are you ready to lose weight and heal your body for life (without dieting, drugs, or making yourself miserable)?

Our free on-demand video training will walk you through how to make this THE year you set health goals…and keep them. Access our free video training HERE.

Raise your hand if the biggest reason you haven't actually changed the way you eat is that you're afraid you'll have to give up all the food you love forever.

But what if I told you that's not actually true?

And what if I told you that the whole point of HEALING YOUR BODY from the inside out—the very thing I talk about over and over again on this podcast, is to get you to a place where you actually feel FREE.

TRULY free.

Free to indulge if and when you really want to, but not beholden to food addictions.

Free to enjoy the best of EVERYTHING life has to offer, without going back into that shame spiral.

Free to look and feel your absolute best all the time, and to actually trust the signals your body is giving you?

Free to think about something OTHER than food all the time.

Because it occurred to me recently that as much time as I spend on this podcast talking about the problem and the solution, I don't actually spend a lot of time talking about what it actually LOOKS like to finally be free. 

What it actually looks like, day to day, to know your body has been healed, that you've reversed your insulin resistance and balanced your hormones and restored your gut health, and that your metabolism is actually working the way it should.

And maybe if I talked about that more, taking the steps to actually get to that point wouldn't feel quite so scary.

So today, let's talk about it.

Are you ready to lose weight and heal your body for life (without dieting, drugs, or making yourself miserable)?

Our free on-demand video training will walk you through how to make this THE year you set health goals…and keep them. Access our free video training HERE.

Fair warning, friends, I’m coming in hot today, and this episode might get a little bit spicy.

In fact, I seriously considered calling this episode, "Why Oprah is full of [you know what!]," but I thought that might not make it past the censors.

Yep, I really just said that.  I told you it was gonna be spicy!

Because I don't know about you, but I recently watched Oprah’s big weight loss special and I have a LOT of thoughts.

In case you missed it, let me fill you in: The special was called, "Shame, Blame, and the Weight Loss Revolution," and for lack of a better word, it was literally just an hour-long infomercial for Ozempic and other weight loss drugs.

Her "revolution" was that Ozempic is awesome, and that everyone--including KIDS apparently--should take it without hesitation, nevermind the fact that it's ridiculously expensive, comes with a ton of scary side effects, and you have to keep taking it for LIFE or you'll gain all your weight back.

Suffice to say, I was not a fan.  Honestly, the whole thing made me feel sick, knowing just how many women love and adore Oprah, and trust her to give them what they think is good advice.

Because this was not good advice.  And today, I want to talk about why.

Are you ready to lose weight and heal your body for life (without dieting, drugs, or making yourself miserable)?

Our free on-demand video training will walk you through how to make this THE year you set health goals…and keep them. Access our free video training HERE.