EHA Unplugged – Détails, épisodes et analyse

Get up to date with the latest EHA-EU guideline for Mantle Cell Lymphoma (EHA–EU MCL network guidelines for diagnosis and treatment of mantle cell lymphoma - Jerkeman - 2025 - HemaSphere - Wiley Online Library) with Prof Mats Jerkeman (Lund University, Sweden).  

In this episode, he explains how biological risk factors, particularly TP53 mutations and proliferation rate, inform patient stratification. He reviews evolving treatment sequencing, including  the expanding role of  BTK inhibitors (such as ibrutinib) in first-line regimens. 

He further discusses the management relapsed/refractory MCL, where BTK inhibitors and CAR T-cell therapy  have largely supplanted but not fully replaced allogeneic transplantation. 

Throughout the conversation, Prof Jerkeman emphasizes the dynamic evolution of MCL treatment and the need for ongoing guideline updates as new evidence emerges. 

Link to the guideline: (EHA–EU MCL network guidelines for diagnosis and treatment of mantle cell lymphoma - Jerkeman - 2025 - HemaSphere - Wiley Online Library) 

Link to Lund University:  

Mats Jerkeman - Lund University 

Home | Lund University  

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Interested in more content related to CART? We've got you covered. Check out free CART program on ⁠EHA Campus⁠.

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[This is a Rerelease. Episode first published on July 19, 2024.]Join us for a conversation with Jonathan Clark, a patient advocate who has been in remission for over five years after receiving CAR T-cell therapy for Mantle Cell Lymphoma.

Jonathan shares his journey from relapse to recovery, detailing the challenges and triumphs of this cutting-edge treatment from a patient’s perspective. With host Dr. Sarah de Vlieger, they discuss his motivation for sharing his story and the profound physical and psychological impacts of long-term remission.

Jonathan also talks about managing long-term side effects like immunodeficiencies and how apparently small changes can significantly improve quality of life. He emphasizes the importance of understanding the patient's perspective, advocating for quality of life improvements, and the need for personalized care that goes beyond medical statistics. Jonathan highlights the global disparities in accessing advanced treatments like CAR T-cell therapy and concludes with a call to prioritize quality of life in treatment decisions. 

Host: Dr Sarah de Vlieger

Guest: Jonathan Clark

This episode is part of a series recorded at the joint EHA-EBMT 6th European CAR T-cell meeting in Valencia in February 2024.

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Interested in more content related to CART? We've got you covered. Check out free CART program on ⁠EHA Campus⁠.

What did you think of this podcast? Share your opinions with us in this short feedback survey.

⁠Provide Feedback⁠

Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

⁠https://ehaedu.org/Campus⁠

Subscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.

Follow EHA on Instagram: ⁠https://www.instagram.com/EHA_Hematology/⁠

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Email us: education@ehaweb.org

Subscribe to receive the EHA Educational Updates via ⁠https://eha.news/subscribe⁠ 

Join us for this interview with Dr Ferran Nadeu Prat from August Pi i Sunyer Biomedical Research Institute in Barcelona, Spain who discusses his work on evolution of chronic lymphocytic leukemia (CLL), which he conducted thanks to the EHA Junior Research Grant.

Dr Nadeu Prat explains how the new insights into CLL evolution toward Richter transformation, which is a lethal complication of CLL, may lead to new therapeutic approaches.

Tune in to hear his views on the future of this field and the role of collaborative research in achieving these goals.

Host: Isabel Olivera-Martinez, PhD, Medical Writer 

Guest: Dr Ferran Nadeu Prat, August Pi i Sunyer Biomedical Research Institute, Barcelona, Spain

What did you think of this podcast? Share your opinions with us in this short feedback survey.

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Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

https://ehaedu.org/Campus

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In this episode Dr Wilson Lim interviews our guest Prof. Carlos Fernández de Larrea on CAR-T toxicities and how to control or avoid adverse reactions to CAR-T therapies in patients with myeloma.

Guest: Prof. Carlos Fernández de Larrea ; Host: Dr Wilson Lim

This podcast episode is part of our FREE course on CAR-T Updates on the EHA Campus. Prominent experts provide an overview of CAR-T treatment in different diseases, discussing clinical management, economic and regulatory aspects, and future developments. 

What did you think of this podcast? Share your opinions with us in a short feedback survey.

Learn more:

Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

https://ehaedu.org/Campus

Subscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.

Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/

Facebook: https://e-h-a.link/facebook

LinkedIn: https://www.linkedin.com/company/eha/

Email us: education@ehaweb.org

Subscribe to receive the EHA Educational Updates via https://eha.news/subscribe 

Listen as Dr. Anna Sureda discusses CAR-T therapy from a patients perspective and the steps that physicians can take to help patients overcome the challenges that comes with CAR-T treatment.

This podcast episode is part of our FREE course on CAR-T Updates on the EHA Campus. Prominent experts provide an overview of CAR-T treatment in different diseases, discussing clinical management, economic and regulatory aspects, and future developments. 

What did you think of this podcast? Share your opinions with us in a short feedback survey.

Guest: Dr Anna Sureda ; Host: Dr Wilson Lim

Learn more:

Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

https://ehaedu.org/Campus

Subscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.

Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/

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LinkedIn: https://www.linkedin.com/company/eha/

Email us: education@ehaweb.org

Subscribe to receive the EHA Educational Updates via https://eha.news/subscribe 

Listen as Emeritus Prof Robin Foà brings you on the journey of Ph+ ALL management together with our host Dr Enrica Orsini. With a long career in ALL, Prof Foà runs through the history of Ph+ ALL, his experience in patient management, and then brings you up to date on the current picture in patient management.

Tune in as Prof Foà describes the breakthrough in treatment with TKI inhibitors and the introduction of the immunotherapeutic drug blinatumomab in Ph+ ALL.

Guest: Emeritus Prof. Robin Foà

Host: Dr. Enrica Orsini

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What did you think of this podcast? Share your opinions with us in this short feedback survey.

Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

https://ehaedu.org/Campus

Subscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.

Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/

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Join us for another episode of EHA Unplugged. We have Prof. Herman Einsele here talking about the current landscapes of CAR-T therapy in myeloma, results achievable today, and the future perspectives for these patients.

This podcast episode is part of our FREE course on CAR-T Updates on the EHA Campus. Prominent experts provide an overview of CAR-T treatment in different diseases, discussing clinical management, economic and regulatory aspects, and future developments. 

What did you think of this podcast? Share your opinions with us in a short feedback survey.

Guest: Prof Herman Einsele

Learn more:

Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

https://ehaedu.org/Campus

Subscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.

Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/

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Email us: education@ehaweb.org

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Join us here at EHA Unplugged with another episode on CAR-T updates. Listen as our guest Prof. Chiara Bonini and host Dr. Wilson Lim discuss the reasons for CAR-T therapy failure and relapse after treatment.

This podcast episode is part of our FREE course on CAR-T Updates on the EHA Campus. Prominent experts provide an overview of CAR-T treatment in different diseases, discussing clinical management, economic and regulatory aspects, and future developments. 

What did you think of this podcast? Share your opinions with us in a short feedback survey.

If you liked this podcast and would like to explore related content, you can check out our CAR-T program on the EHA Campus.

Guest: Prof. Chiara Bonini ; Host: Dr. Wilson Lim

Learn More:

Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

https://ehaedu.org/Campus

Subscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.

Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/

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LinkedIn: https://www.linkedin.com/company/eha/

Email us: education@ehaweb.org

Subscribe to receive the EHA Educational Updates via https://eha.news/subscribe 

Listen as Prof. Christian Chabannon provides an overview of the challenges and obstacles raised by the economic aspects of CAR-T treatment. He examines different solutions and proposes a way forward to address these issues.

This podcast episode is part of our FREE course on CAR-T Updates on the EHA Campus. Prominent experts provide an overview of CAR-T treatment in different diseases, discussing clinical management, economic and regulatory aspects, and future developments. 

What did you think of this podcast? Share your opinions with us in a short feedback survey.

If you liked this podcast and would like to explore related content, you can check out our CAR-T program on the EHA Campus.

Guest: Prof. Christian Chabannon ; Host: Dr. Olivera Martinez

Learn More

Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

https://ehaedu.org/Campus

Subscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.

Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/

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LinkedIn: https://www.linkedin.com/company/eha/

Email us: education@ehaweb.org

Subscribe to receive the EHA Educational Updates via https://eha.news/subscribe 

Listen as Prof. John Gribben provides an update on where we are with CAR-T in acute and chronic leukemias. 

This podcast episode is part of our FREE course on CAR-T Updates on the EHA Campus. Prominent experts provide an overview of CAR-T treatment in different diseases, discussing clinical management, economic and regulatory aspects, and future developments. 

What did you think of this podcast? Share your opinions with us in a short feedback survey.

If you liked this podcast and would like to explore related content, you can check out our CAR-T program on the EHA Campus.

Would you like to explore more eLearning or podcasts? Please visit the EHA Campus.

https://ehaedu.org/Campus

Subscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.

Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/

Facebook: https://e-h-a.link/facebook

LinkedIn: https://www.linkedin.com/company/eha/

Email us: education@ehaweb.org

Subscribe to receive the EHA Educational Updates via https://eha.news/subscribe