ClinicalNews.Org – Détails, épisodes et analyse

The present study demonstrates that green tea extract and ginger supplementation, individually and in combination, enhanced endurance performance, metabolic efficiency, and thermal perception in recreationally active males under normothermic and cold conditions. Green tea alone increased time to exhaustion and reduced respiratory exchange ratio in normothermic conditions, indicating improved fat oxidation and endurance capacity. In cold conditions, the combination of green tea and ginger enhanced time to exhaustion, lowered the respiratory exchange ratio, improved thermal sensation, and reduced muscle soreness. These effects are most pronounced in cold environments, where the combined supplementation mitigated the heightened physiological demands of cold exposure while amplifying metabolic benefits. To our knowledge, this is the first randomized, double-blind crossover trial to systematically evaluate the supportive combined effects of green tea and ginger across different environmental conditions.

A 2025 study in the journal Nutrients investigated the effects of green tea extract and ginger on endurance performance in different temperatures. In a randomized, double-blind crossover trial, sixteen recreationally active males were tested under eight different conditions. The conditions included taking a placebo, 500 mg of green tea extract, 1000 mg of ginger, or a combination of both, each in normal (normothermic) and cold environments (

). In normal temperatures, both green tea alone and the combined supplement significantly increased the time-to-exhaustion (endurance) and reduced the respiratory exchange ratio (RER), indicating greater fat oxidation, compared to the placebo. In cold conditions, the combination of green tea and ginger was most effective, significantly enhancing endurance, improving thermal sensation (feeling warmer), and reducing RER compared to both placebo and ginger alone. All active supplements (green tea, ginger, and combined) also significantly decreased muscle soreness 24 hours after exercise in the cold compared to the placebo.

Disclaimers:

• "This information is for educational purposes only and should not be interpreted as medical advice."

• "The study discussed was conducted on a small sample of 16 recreationally active males. The findings cannot be extrapolated to women, older adults, or competitive athletes, and further research is needed."

• "Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."

• "This channel is not monetized and does not provide medical advice."

• (Reminder: Please include a verbal disclaimer in the video itself.)

#GreenTea #Ginger #EndurancePerformance #ColdEnvironment #FatOxidation

Demirli, A.; Ulupınar, S.; Terzi, M.; Özbay, S.; Özkara, A.B.; Gençoğlu, C.; Ouergui, L; Ardigò, L.P. Synergistic Effects of Green Tea Extract and Ginger Supplementation on Endurance Performance and Thermal Perception in Normothermic and Cold Environments: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial. Nutrients 2025, 17, 2949. https://doi.org/10.3390/nu17182949.

Alchepharma,Ralph Turchiano,citation,research,study,green tea extract,ginger supplementation,endurance performance,cold environment,normothermic,thermal perception,fat oxidation,time to exhaustion,perceived exertion,muscle soreness,synergistic effects,catechins,epigallocatechin gallate,gingerols,ergogenic aids,thermogenesis,randomized controlled trial,crossover trial,exercise physiology,submaximal exercise,VO2 max,sports nutritionNarrator: Ralph Turchiano, AlchePharma CEO

A major scientific review looked at the best available evidence on apple cider vinegar (ACV) and its effects on body weight. Researchers combined the results from 9 different studies that included adults who were overweight, obese, or had type 2 diabetes.

Here’s what they found:

• Taking ACV daily was linked to a significant drop in body weight, BMI, and waist size.

• The authors calculated this could amount to an average weight loss of about 7.4 kg (over 16 pounds).

• The most effective approach seemed to be taking about two tablespoons (30 mL) per day for up to 12 weeks.

The main takeaway is that science suggests ACV may be a helpful tool for short-term weight management.

Disclaimers:

"This information is for educational purposes only and should not be interpreted as medical advice."

"The study discussed is a meta-analysis of randomized controlled trials conducted on adult humans who were overweight, obese, or had type 2 diabetes. The intervention periods in the included studies were relatively short, ranging from 4 to 12 weeks."

"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."

"This channel does not provide medical advice."

#AppleCiderVinegar #WeightLoss #BodyComposition #MetaAnalysis #ObesityResearch

Source Article Citation:

Castagna, A.; Ferro, Y.; Noto, F.R.; et al. Effect of Apple Cider Vinegar Intake on Body Composition in Humans with Type 2 Diabetes and/or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients 2025, 17, 3000. DOI: https://doi.org/10.3390/nu17183000

Apple cider vinegar, ACV, acetic acid, weight management, body composition, obesity, overweight, type 2 diabetes, meta-analysis, randomized controlled trial, RCT, body weight, BMI, body mass index, waist circumference, visceral adiposity, anthropometric measurements, weight loss, dietary supplement, short-term weight management, metabolic health, adiposity, nutritional intervention, systematic review, dose-response

A recent randomized, placebo-controlled, crossover trial investigated the link between high-dose oral thiamine supplementation and chronic fatigue in 40 patients with quiescent inflammatory bowel disease (qIBD). The study found that while high-dose thiamine (600-1800 mg/day for 4 weeks) significantly reduced fatigue, it did not alter the overall gut microbiota composition or short-chain fatty acid (SCFA) concentrations.

Instead, the study revealed a significant correlation: patients with higher baseline levels of the gut bacteria Faecalibacterium prausnitzii and Roseburia hominis were more likely to respond positively to thiamine treatment. Specifically, Faecalibacterium prausnitzii was more abundant in thiamine responders both before (P=.019) and after (P=.038) treatment. The relative abundance of both Faecalibacterium prausnitzii and Roseburia hominis inversely correlated with improvements in IBD fatigue scores. Of the patients classified as responders (those who decreased their IBD-FQ1 score by 3 or more points), all 17 individuals showed this positive response. Furthermore, Faecalibacterium prausnitzii abundance was significantly greater in these responders compared to nonresponders. These findings suggest that these specific bacteria may serve as markers to predict who will benefit from thiamine for IBD-related fatigue, rather than being directly modified by the thiamine itself.

3. Disclaimers:

"This information is for educational purposes only and should not be interpreted as medical advice." "The study discussed was conducted on a specific population (patients with quiescent inflammatory bowel disease). Further research may be needed to confirm these findings in other populations." "Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications." "This channel is not monetized and does not provide medical advice."

#IBDFatigue #Thiamine #IBD #FaecalibacteriumPrausnitzii #InflammatoryBowelDisease

Thiamine-Reduced Fatigue in Quiescent Inflammatory Bowel Disease Is Linked to Faecalibacterium prausnitzii Abundance Bermúdez-Sánchez, Sandra et al. Gastro Hep Advances, Volume 4, Issue 1, 100533

Alchepharma,Ralph Turchiano,citation,Thiamine inflammatory bowel disease fatigue,quiescent IBD fatigue treatment,Faecalibacterium prausnitzii IBD,Roseburia hominis fatigue,gut microbiota IBD fatigue,vitamin B1 IBD,chronic fatigue IBD,butyrate gut bacteria,gut-brain axis IBD,microbial diversity IBD,thiamine supplementation benefits,Crohn's disease fatigue,ulcerative colitis fatigue,fatigue biomarkers IBD,gut health IBD,Faecalibacterium prausnitzii abundance

This study explores the exciting potential of lycopene, a natural compound found in tomatoes, for combating liver disease. Researchers followed participants for over a decade, finding a link between higher lycopene intake and a reduced risk of fatty liver disease (NAFLD). The study even identified a specific daily dosage (around 9.5mg) that showed the strongest protective effect. This video will break down the science behind lycopene's potential benefits, including its antioxidant and anti-inflammatory properties, and how it might specifically target liver health.

#LycopeneResearch #NALFLDprevention #LiverHealth

Donghia R, Campanella A, Bonfiglio C, Cuccaro F, Tatoli R, Giannelli G. Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study. Nutrients. 2024; 16(4):562. https://doi.org/10.3390/nu16040562

lycopene benefits, liver health foods, foods for fatty liver disease, natural ways to improve liver health, antioxidant rich foods, lycopene and liver disease, NUTRIHEP study, lycopene dosage for liver health, how to reduce risk of NAFLD, is tomato good for liver, non-alcoholic fatty liver disease (NAFLD), antioxidant properties, anti-inflammatory properties, free radicals, liver disease prevention, liver cirrhosis, cardiovascular disease prevention, immune system support, AFLD, FLD

This study explores the exciting potential of lycopene, a natural compound found in tomatoes, for combating liver disease. Researchers followed participants for over a decade, finding a link between higher lycopene intake and a reduced risk of fatty liver disease (NAFLD). The study even identified a specific daily dosage (around 9.5mg) that showed the strongest protective effect. This video will break down the science behind lycopene's potential benefits, including its antioxidant and anti-inflammatory properties, and how it might specifically target liver health.

#LycopeneResearch #NALFLDprevention #LiverHealth

Donghia R, Campanella A, Bonfiglio C, Cuccaro F, Tatoli R, Giannelli G. Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study. Nutrients. 2024; 16(4):562. https://doi.org/10.3390/nu16040562

lycopene benefits, liver health foods, foods for fatty liver disease, natural ways to improve liver health, antioxidant rich foods, lycopene and liver disease, NUTRIHEP study, lycopene dosage for liver health, how to reduce risk of NAFLD, is tomato good for liver, non-alcoholic fatty liver disease (NAFLD), antioxidant properties, anti-inflammatory properties, free radicals, liver disease prevention, liver cirrhosis, cardiovascular disease prevention, immune system support, AFLD, FLD

This study reveals a strong link between low levels of both selenium and zinc and significantly reduced survival rates in prostate cancer patients. Our findings suggest that optimizing both elements could be crucial for improving survival outcomes. We call for further research to determine the ideal levels for different regions, paving the way for potential personalized treatment approaches.

#ProstateCancerResearch #SeleniumZinc #SurvivalOutcomes

Pietrzak S, Marciniak W, Derkacz R, Matuszczak M, Kiljańczyk A, Baszuk P, Bryśkiewicz M, Sikorski A, Gronwald J, Słojewski M, et al. Correlation between Selenium and Zinc Levels and Survival among Prostate Cancer Patients. Nutrients. 2024; 16(4):527. https://doi.org/10.3390/nu16040527

prostate cancer, selenium, zinc, survival, combined deficiency, prognosis, biomarker, Se, Zn, blood levels, optimal levels, element therapy, micronutrients, essential trace elements, personalized medicine, targeted therapy, dietary factors, cancer treatment, complementary medicine, alternative therapy

This study reveals a strong link between low levels of both selenium and zinc and significantly reduced survival rates in prostate cancer patients. Our findings suggest that optimizing both elements could be crucial for improving survival outcomes. We call for further research to determine the ideal levels for different regions, paving the way for potential personalized treatment approaches.

#ProstateCancerResearch #SeleniumZinc #SurvivalOutcomes

Pietrzak S, Marciniak W, Derkacz R, Matuszczak M, Kiljańczyk A, Baszuk P, Bryśkiewicz M, Sikorski A, Gronwald J, Słojewski M, et al. Correlation between Selenium and Zinc Levels and Survival among Prostate Cancer Patients. Nutrients. 2024; 16(4):527. https://doi.org/10.3390/nu16040527

prostate cancer, selenium, zinc, survival, combined deficiency, prognosis, biomarker, Se, Zn, blood levels, optimal levels, element therapy, micronutrients, essential trace elements, personalized medicine, targeted therapy, dietary factors, cancer treatment, complementary medicine, alternative therapy

Sun got you down? Say goodbye to wrinkles and hello to youthful skin with a surprising hero: cloves! This study found that feeding mice a special clove extract called isoeugenol while exposing them to sun-like rays actually reversed aging signs! Imagine, smoother, less dry skin and thicker collagen, all thanks to a common spice! Plus, the good news doesn't stop there - the extract even balanced their gut bacteria, which can also impact skin health. This is a game-changer for natural anti-aging solutions! While more research is needed, this spicy discovery is definitely something to get excited about - your skin (and gut) might just thank you for it!

#NaturalAntiAging #SpiceUpYourSkincare #GutSkinConnection

Geng, R., Kang, S., Huang, K., & Tong, T. (2024). Dietary Isoeugenol Supplementation Attenuates Chronic UVB-Induced Skin Photoaging and Modulates Gut Microbiota in Mice. Nutrients, 16(4), 481. https://doi.org/10.3390/nu16040481

clove oil, skin aging, wrinkles, sun damage, natural remedy, gut health, anti-aging, mice study, isoeugenol, collagen, UV protection, healthier skin, microbiome, DIY skincare, affordable anti-aging, prevent wrinkles, natural collagen booster, gut bacteria for skin, kitchen ingredient beauty hack, sun protection alternative, healthy aging

Sun got you down? Say goodbye to wrinkles and hello to youthful skin with a surprising hero: cloves! This study found that feeding mice a special clove extract called isoeugenol while exposing them to sun-like rays actually reversed aging signs! Imagine, smoother, less dry skin and thicker collagen, all thanks to a common spice! Plus, the good news doesn't stop there - the extract even balanced their gut bacteria, which can also impact skin health. This is a game-changer for natural anti-aging solutions! While more research is needed, this spicy discovery is definitely something to get excited about - your skin (and gut) might just thank you for it!

#NaturalAntiAging #SpiceUpYourSkincare #GutSkinConnection

Geng, R., Kang, S., Huang, K., & Tong, T. (2024). Dietary Isoeugenol Supplementation Attenuates Chronic UVB-Induced Skin Photoaging and Modulates Gut Microbiota in Mice. Nutrients, 16(4), 481. https://doi.org/10.3390/nu16040481

clove oil, skin aging, wrinkles, sun damage, natural remedy, gut health, anti-aging, mice study, isoeugenol, collagen, UV protection, healthier skin, microbiome, DIY skincare, affordable anti-aging, prevent wrinkles, natural collagen booster, gut bacteria for skin, kitchen ingredient beauty hack, sun protection alternative, healthy aging

In a scientific knockout, a study found that athletes who consumed both alkaline water and L-glutamine before exercise experienced a significant boost in salivary α-amylase activity, indicating enhanced immunity. They also saw a rise in testosterone levels, potentially indicating faster muscle recovery. While the mechanisms require further investigation, this suggests a possible synergistic effect between the two substances. Although research focuses on athletes, it raises intriguing possibilities for anyone seeking to optimize recovery and potentially improve immune function. Remember, science is always evolving, offering new tools to support your well-being.

#SportRecovery #AlkalineWater #LGlutamine

Lu, T., He, C., Suzuki, K., Lu, C., Wang, C., & Fang, S. (2024). Concurrent Ingestion of Alkaline Water and L-Glutamine Enhanced Salivary α-Amylase Activity and Testosterone Concentration in Boxing Athletes. Nutrients, 16(3), 454. https://doi.org/10.3390/nu16030454

boxing, testosterone boost, alkaline water, L-glutamine, immune function, muscle recovery, salivary markers, training performance, athlete study, randomized controlled trial, pre-workout supplement, hydration,, sport science, recovery, glutamine benefits,alkaline water research, amylase, mucosal, immune