The PKD Dietitian Podcast – Details, episodes & analysis

Listener Q:  "What is the difference between eGFR and GFR? Is one better than the other for getting tested for PKD, or should I ask for both? I am worried I am not getting the labs I need to stay informed about my kidneys."

Answer: Tune in and find out:

• What GFR is
• What eGFR is
• If there are the same
• What you need to know about each and if you need to get both tested for Polycystic Kidneys

MASTER YOUR LABS FOR PKD

• Yes, Sign Me Up!
• Learn More - https://www.thepkddietitian.com/masteryourlabs   

RESOURCES

• Episode #33 What is Cystatin C and Should You Get it Tested? https://www.thepkddietitian.com/podcasts/the-pkd-dietitian-podcast/episodes/2148345282 
• NKF’s eGFR Calculator https://www.kidney.org/professionals/gfr_calculator   

LET’S CONNECT

INSTAGRAM: https://www.instagram.com/the.pkd.dietitian/

FACEBOOK: https://www.facebook.com/PKDdietitian

EMAIL ME: https://www.thepkddietitian.com/site/contact

DISCLAIMER: The PKD Dietitian Podcast is meant for educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. 

In this episode of The PKD Dietitian Podcast, Diana Bruen answers a listener's question about the safety of eating nightshades like eggplant and red peppers for those with polycystic kidney disease (PKD). She breaks down what nightshades are, why some people avoid them, and what the research really says. Forget the conflicting advice online—Diana shares the evidence-based truth about how nightshades impact your kidney health and whether they belong in a PKD-friendly diet.

SEND A PODCAST QUESTION OR REQUEST

https://www.thepkddietitian.com/site/contact

REFERENCES

1. Is There Such a Thing as “Anti-Nutrients”? A Narrative Review of Perceived Problematic Plant Compounds https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600777/
2. 130 years of Plant Lectin Research https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455784/
3. Red kidney bean poisoning in the UK: an analysis of 50 suspected incidents between 1976 and 1989 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271815/
4. Structure-function and application of plant lectins in disease biology and immunity https://pubmed.ncbi.nlm.nih.gov/31542433/
5. Nightshade Vegetables: A Dietary Trigger for Worsening Inflammatory Bowel Disease and Irritable Bowel Syndrome? https://pubmed.ncbi.nlm.nih.gov/37202602/
6. The Harvard Nutrition Source https://nutritionsource.hsph.harvard.edu/anti-nutrients/lectins/
7. Natural toxins in food https://www.who.int/news-room/fact-sheets/detail/natural-toxins-in-food
8. Natural Toxins in Food https://www.fda.gov/food/chemical-contaminants-pesticides/natural-toxins-food  

DISCLAIMER

The PKD Dietitian Podcast is for educational purposes only.  Information presented should not be used in place of advice from a medical professional.   Always consult your healthcare provider with any medical questions or concerns.

What is vasopressin and how is it connected to Polycystic Kidney Disease? In this episode, the PKD Dietitian is going to:

• Break down exactly what vasopressin is.
• Explain how it functions in the body and how it affects your kidneys.
• Highlight how it impacts PKD cyst growth.
• PLUS share dietary and lifestyle factors that impact vasopressin levels...for better or worse.

RESOURCES

BLOG: What is a Good Fluid Goal for Polycystic Kidney Disease?

EPISODE 3:  Listener Q - How Much Water Should I Drink?

REFERENCES

• Torres VE. Salt, water, and vasopressin in polycystic kidney disease. Kidney Int. 2020;98(4):831-834. doi:10.1016/j.kint.2020.06.001 ARTICLE LINK
• Van Gastel MDA, Torres VE. Polycystic Kidney Disease and the Vasopressin Pathway. Ann Nutr Metab. 2017;70 Suppl 1:43-50. doi:10.1159/000463063 ARTICLE LINK
• Taylor JM, Hamilton-Reeves JM, Sullivan DK, et al. Diet and polycystic kidney disease: A pilot intervention study. Clin Nutr. 2017;36(2):458-466. doi:10.1016/j.clnu.2016.01.003 ARTICLE LINK
• Amro OW, Paulus JK, Noubary F, Perrone RD. Low-Osmolar Diet and Adjusted Water Intake for Vasopressin Reduction in Autosomal Dominant Polycystic Kidney Disease: A Pilot Randomized Controlled Trial. Am J Kidney Dis. 2016;68(6):882-891. doi:10.1053/j.ajkd.2016.07.023 ARTICLE LINK
• Maatje D.A. van Gastel, Vicente E. Torres; Polycystic Kidney Disease and the Vasopressin Pathway. Ann Nutr Metab 15 June 2017; 70 (Suppl. 1): 43–50. ARTICLE LINK
• Torres, Vicente E.; Harris, Peter C. Strategies Targeting cAMP Signaling in the Treatment of Polycystic Kidney Disease. Journal of the American Society of Nephrology 25(1):p 18-32, January 2014. | DOI: 10.1681/ASN.2013040398 ARTICLE LINK
• Wang, Xiaofang; Wu, Yanhong; Ward, Christopher J.; Harris, Peter C.; Torres, Vicente E.. Vasopressin Directly Regulates Cyst Growth in Polycystic Kidney Disease. Journal of the American Society of Nephrology 19(1):p 102-108, January 2008. | DOI: 10.1681/ASN.2007060688 ARTICLE LINK
• Tasneem M, Mannix C, Wong A, Zhang J, Rangan G. Is serum copeptin a modifiable biomarker in autosomal dominant polycystic kidney disease?. World J Nephrol. 2018;7(2):51-57. doi:10.5527/wjn.v7.i2.51 ARTICLE LINK
• Bankir L, Roussel R, Bouby N. Protein- and diabetes-induced glomerular hyperfiltration: role of glucagon, vasopressin, and urea. Am J Physiol Renal Physiol. 2015;309(1):F2-F23. doi:10.1152/ajprenal.00614.2014 ARTICLE LINK
• Alwis US, Delanghe J, Dossche L, et al. Could Evening Dietary Protein Intake Play a Role in Nocturnal Polyuria?. J Clin Med. 2020;9(8):2532. Published 2020 Aug 5. doi:10.3390/jcm9082532 ARTICLE LINK
• Grantham, Jared J.. Therapy for Polycystic Kidney Disease? It's Water, Stupid!. Journal of the American Society of Nephrology 19(1):p 1-7, January 2008. | DOI: 10.1681/ASN.2007101100 ARTICLE LINK
• Yamada Y, Fujiki H, Mizuguchi H, et al. Nihon Yakurigaku Zasshi. 2022;157(4):254-260. doi:10.1254/fpj.22006 ARTICLE LINK
• Rangan GK, Wong ATY, Munt A, et al. Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease. NEJM Evid. 2022;1(1):EVIDoa2100021. doi:10.1056/EVIDoa2100021 ARTICLE LINK
• Sparapani S, Millet-Boureima C, Oliver J, et al. The Biology of Vasopressin. Biomedicines. 2021;9(1):89. Published 2021 Jan 18. doi:10.3390/biomedicines9010089 ARTICLE LINK

DISCLAIMER

The PKD Dietitian Podcast is meant for educational purposes only.  Information presented should not be used in place of advice from a medical professional.

Listener Q Episode + FAQs 

Q: "I occasionally fast but am considering doing a long fast, like the 3-day water fast that was done in the study.  What do you think of extended fasting?  Is it good for PKD?"

A: Tune in and find out:

• If there are benefits for PKD with an extended water fast
• The PKD Dietitians' thoughts on if you should try a water fast
• FAQs on whether you should do keto
• FAQs on how much fluid you should drink
• If labs are a good marker of sodium intake
• PLUS ways to work with the PKD Dietitian

RESOURCES MENTIONED

Episode 14: How I Became The PKD Dietitian

Episode 19: Ketogenic Diets: Are They Good for PKD?

Episode 34: KETO-ADPKD: What Were The Study's Results?

Blog: What is a Good Fluid Goal for Polycystic Kidney Disease?

QUESTIONS?

Do you have a question for The PKD Dietitian or a topic you would like covered?  

Contact The PKD Dietitian

REFERENCES 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369953

https://pubmed.ncbi.nlm.nih.gov/37377031/

https://pubmed.ncbi.nlm.nih.gov/29455546/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929006/

 DISCLAIMER

The PKD Dietitian Podcast is meant for educational purposes only.  Information presented should not be used in place of advice from a medical professional.  

 In this shorty episode, The PKD Dietitian tackles the Carnivore diet,  what it really is, why folks with PKD are doing it, and provides her thoughts (scientifically backed of course) on whether the meat-based dietary craze is good for Polycystic Kidney Disease.

RESOURCES:

• PKD KETO PRO: https://www.thepkddietitian.com/nutritionprograms
• KETO MASTERY PROGRAM: https://www.thepkddietitian.com/ketomasteryprogram

CONNECT WITH THE PKD DIETITIAN

• INSTAGRAM: https://www.instagram.com/the.pkd.dietitian/
• FACEBOOK: https://www.facebook.com/PKDdietitian
• PINTEREST: https://www.pinterest.com/PKDDietitian

REFERENCES

• Can a carnivore diet provide all essential nutrients? 
• Micronutrient Gaps in Three Commercial Weight-Loss Diet Plans
• Behavioral Characteristics and Self-Reported Health Status among 2029 Adults Consuming a "Carnivore Diet" 
• Limitations of Self-reported Health Status and Metabolic Markers among Adults Consuming a "Carnivore Diet"

DISCLAIMER: The PKD Dietitian Podcast is meant for educational purposes.  The information provided shouldn’t be considered a substitute for professional medical advice, diagnosis, or treatment.

In this episode of the PKD Dietician podcast, host Diana Bruen talks with guest Emily Fraser about family planning with polycystic kidney disease (PKD). Emily shares her journey, including her decision to use IVF and preimplantation genetic testing (PTM) to conceive a child without ADPKD.  We discuss the IVF process, and the emotional and ethical considerations often involved. The episode highlights the importance of genetic testing and the support available for those seeking to prevent passing PKD to their children.

CONNECT WITH EMILY

• Website: https://www.emilyfraser.ca/
• Instagram: https://www.instagram.com/thespooniementor/
• Program: https://www.emilyfraser.ca/tsp

CONNECT WITH pkDO

PKD Outreach Foundation

• Website: https://www.pkdo.org/
• Instagram: https://www.instagram.com/pkd_outreach/
• Info on IVF + PGTM: https://www.pkdo.org/pkd-free-babies

DISCLAIMER

Content on The PKD Dietitian Podcast is for informational purposes, it isn't intended as medical advice. Please consult your Dietitian and/or healthcare provider for individual recommendations.

In this episode, The PKD Dietitian talks about three labs she wants you to ask for each year - Vitamin D, PTH, and Uric Acid.  Learn more about the labs, why they are important for your kidney health, and your next steps to be a proactive member of your healthcare journey.

RESOURCES:

• EPISODE 17: Vitamin D and PKD: How To Supplement Safely
• BLOG: The Ultimate Guide to Vitamin D and Polycystic Kidney Disease 

Do you have a question for the PKD Dietitian or a topic you would like covered?  

 Contact The PKD Dietitian 

DISCLAIMER:

The PKD Dietitian Podcast is meant for educational purposes only.  Information presented should not be used in place of advice from a medical professional.  

As we start this new year, it's the perfect time to check in around mindset and dietary changes to support PKD Health.  How we talk and think about dietary changes is important.

Join The PKD Dietitian as she looks at the difference between choose vs. cheat when it comes to meals, whole days, and dietary decisions.

HIGHLIGHTS

• Shifting from "cheating" to "choosing" and the significance of consistent, positive dietary changes
• The power of understanding your 'why'
• Embracing celebrations and traditions while maintaining health goal

CONNECT with Diana, The PKD Dietitian!

INSTAGRAM: https://www.instagram.com/the.pkd.dietitian/

FACEBOOK: https://www.facebook.com/PKDdietitian

WEBSITE: https://www.thepkddietitian.com/

DISCLAIMER

The PKD Dietitian Podcast is meant for educational purposes only.  Information presented should not be used in place of advice from a medical professional.

In this episode, The PKD Dietitian geeks out a bit looking at the recently published results of the KETO-ADPKD trial.  This is the very first randomized controlled trial (RCT) looking at PKD and ketogenic diet therapy, if there was any impact on the kidneys, or if it is even doable.  

Listen in for a look at:

- what was being tested

- how the study was set up

- were there any significant results?

- what did the ketogenic diet therapy look like

- The PKD Dietitian's thoughts & questions

CORRECTIONS

1. All participants tested ketones at home using a breath meter.  Only the Ketogenic Diet group had blood ketone levels tested, at their center visits.
2. Participants in the Ketogenic Group received 10%, not 10 grams, of their fat from MCT.

RESOURCES

[FULL ARTICLE] Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD—a randomized controlled trial 

[EPISODE 33] What is Cystatin C and Should You Get it Tested? 

[EPISODE 20] How To Start Keto Safely for Polycystic Kidney Disease (PKD) 

LET'S GET SOCIAL

INSTAGRAM: https://www.instagram.com/the.pkd.dietitian/

FACEBOOK: https://www.facebook.com/PKDdietitian

WEBSITE: https://www.thepkddietitian.com/

DISCLAIMER: The PKD Dietitian Podcast is meant for educational purposes only.  Information presented should not be used in place of advice from a medical professional.  

Listener Q Episode! Tune in and find out:

• How to look at your GFR
• What Creatinine is, and what can affect lab results outside of your kidney function
• What Cystatin C is, and who should talk to their MD about it getting it tested
• The PKD Dietitians thoughts on which is better for PKD

MASTER YOUR LABS FOR PKD

Check out Master Your Labs

50% off coupon: Holiday50

Enroll Today [with instant discount]

RESOURCES

NKF's GFR Calculator

DISCLAIMER

Content on The PKD Dietitian Podcast is for informational purposes, it isn't intended as medical advice. Please consult your Dietitian and/or healthcare provider for individual recommendations.