WolverHeme Happy Hour

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https://meetings-api.hematology.org/api/abstract/vmpreview/296881
3 partages
https://ash.confex.com/ash/2023/webprogram/Paper191921.html
2 partages
https://ash.confex.com/ash/2023/webprogram/Paper180114.html
2 partages

https://pubmed.ncbi.nlm.nih.gov/32673171/
3 partages
https://pubmed.ncbi.nlm.nih.gov/32791048/
3 partages
https://pubmed.ncbi.nlm.nih.gov/33288862/
3 partages

https://www.nature.com/articles/s41571-026-01159-6
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https://www.nature.com/articles/s41375-022-01562-9.pdf
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https://www.nature.com/articles/s41408-025-01222-y
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Houston, we don't have a problem... with APOLLO

Saison 1 · Épisode 26

mercredi 28 août 2024 • Durée 58:37

In this episode, Anthony and Bernie discuss the recently reported APOLLO trial in high-risk APL and debate whether this should represent the new standard of care in this population. We also review key practical considerations for the treatment of APL patients, including side effect management and treatment of APL in unique clinical scenarios.

APOLLO: https://library.ehaweb.org/eha/2024/eha2024-congress/422206/uwe.platzbecker.first.results.of.the.apollo.trial.a.randomized.phase.iii.study.html

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From Ancient Remedies to Modern Miracles: The Evolution of APL Treatment

Saison 1 · Épisode 24

jeudi 13 juin 2024 • Durée 58:05

In this episode, Bernie and Anthony review the full history of APL treatment, in preparation for the upcoming plenary presentation of the APOLLO study THIS WEEKEND at EHA 2024!

How did we get to our current standard of care in APL? How and why did the PETHEMA, GIMEMA, UK MRC, and other cooperative group regimens evolve over time into what they are today?

And importantly, is the APOLLO control arm (no arsenic!), ok? Tune in to find out!

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Common Sense Oncology: Outcomes That Matter

Saison 1 · Épisode 16

mardi 1 août 2023 • Durée 37:41

In this episode, Anthony and Bernie chat with Chris Booth, MD, and Aaron "Papa Heme" Goodman, MD, to talk about the Common Sense Oncology movement!

Join the Common Sense Oncology movement at this link (it's free!): https://commonsenseoncology.org/

Lancet Oncol paper: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00319-4/fulltext

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All too well: the reality of leukemia treatment

Saison 1 · Épisode 15

jeudi 8 juin 2023 • Durée 49:29

In this episode, Anthony, Bernie, and Lydia are joined by a former patient, Madeline B, to talk about her ALL treatment journey. Drawing inspiration from Taylor Swift's upcoming concert and heartfelt ballad ("All Too Well"), this episode tackles some of the unique challenges, emotions, and considerations that come with helping adolescents and young adults (AYA) with treatment for acute leukemia. This is a must-listen for anyone taking care of AYA patients!

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Episode 14: A Quantum Leap in AML Treatment? Dissecting Quizartinib Data with Dr. Dale Bixby

Saison 1 · Épisode 14

mardi 9 mai 2023 • Durée 01:10:20

In this episode, Anthony and Bernie are joined once again by special guest and hematology expert, Dr. Dale Bixby, to discuss the recent publication of the QUANTUM-First study of quizartinib in newly diagnosed AML. Should this study change practice in FLT3-ITD+ AML? Have we made a "Quantum Leap" in the treatment of these patients? Listen for a fun-filled discussion of the data!

Notable References:

QUANTUM-First Study: https://pubmed.ncbi.nlm.nih.gov/37116523/
WolverHeme Episode 8 (Pulling the Goalie on FLT3 Inhibitor Use in AML): https://podcasters.spotify.com/pod/show/wolverheme/episodes/Episode-8-Pulling-the-Goalie-on-FLT3-Inhibitor-Use-in-AML---A-Discussion-with-Dr--Dale-Bixby-e1r6tqt/a-a8tthkc

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Episode 13: You get blinatumomab! You get blinatumomab!

Saison 1 · Épisode 13

vendredi 24 février 2023 • Durée 01:08:03

Blinatumomab - it's Oprah's new favorite drug!

On this episode, Anthony and Bernie are joined by special guests Dr. Lydia Benitez and Dr. Patrick Burke to discuss the ECOG1910 trial of blinatumomab in adult ALL. Is this trial practice changing? Listen and find out!

ECOG1910 Late-Breaking Abstract: https://ash.confex.com/ash/2022/webprogram/Paper171751.html

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Episode 12: Tinder for T Cells - Bispecifics in DLBCL

Saison 1 · Épisode 12

mercredi 8 février 2023 • Durée 58:28

In this episode, we are joined by two lymphoma experts - Victoria Nachar, PharmD, BCOP and Tycel Phillips MD - to discuss the use of bispecific antibodies in Diffuse Large B-Cell Lymphoma (DLBCL)! Stay tuned for an exciting episode where we discuss the data, their possible role in therapy, and what questions and controversies remain.

Relevant Articles:

Review on Design of Bispecifics - https://pubmed.ncbi.nlm.nih.gov/25728220/

Epcoritamab - https://pubmed.ncbi.nlm.nih.gov/36548927/

Glofitamab - https://pubmed.ncbi.nlm.nih.gov/36507690/

Mosunetuzumab - https://pubmed.ncbi.nlm.nih.gov/34914545/

Odronextamab - https://pubmed.ncbi.nlm.nih.gov/35366963/

CRS and ICANS grading - https://pubmed.ncbi.nlm.nih.gov/30592986/

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Episode 11: "Olu the Drunk Snowman" - IDH inhibitors in R/R AML with Dr. Jill Lykon

Saison 1 · Épisode 11

samedi 21 janvier 2023 • Durée 52:30

In this episode, we are joined by Dr. Jill Lykon, Clinical Pharmacist Specialist in Hematology at the University of Miami, to discuss the use of IDH inhibitors in relapsed/refractory AML. How do we choose between IDH inhibitors? Is "Olu" the new standard IDH inhibitor in R/R AML, or just the name of a drunk snowman? What about ivosidenib?

Olutasidenib Phase I - Watts, et al. Lancet. 2023: https://pubmed.ncbi.nlm.nih.gov/36370742/
Olutasidenib Phase II ASH Abstract: https://ash.confex.com/ash/2022/webprogram/Paper167330.html
Ivosidenib Phase I escalation/expansion - Dinardo, et al. NEJM. 2018: https://pubmed.ncbi.nlm.nih.gov/29860938/
Design of olutasidenib and other IDH inhibitors: https://pubmed.ncbi.nlm.nih.gov/31971798/ and https://pubmed.ncbi.nlm.nih.gov/36091829/
Episode 5 of WolverHeme Happy Hour (for background on IDH Inhibitors and frontline data): https://open.spotify.com/episode/4eNXjuGEFFRWTFJF0zsuMw?si=9bd0ae0a488e44ba

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Episode 10: ASH Recap Part 2 - Papa Heme + WolverHeme

Saison 1 · Épisode 10

mercredi 21 décembre 2022 • Durée 01:13:04

In this episode, we are joined by the legendary hematologist and rock star - Dr. Aaron Goodman - aka "Papa Heme"! We discuss which ASH abstracts might be practice changing and which simply don't make the cut. Stay tuned for an entertaining and very educational episode!

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Episode 9: ASH Recap Part 1 - Dauno-Double Trouble

Saison 1 · Épisode 9

mercredi 14 décembre 2022 • Durée 40:04

In this episode, Anthony and Bernie begin to recap some interesting studies presented at ASH, starting with a discussion the results of the "Dauno-Double" Trial. Should it change practice?

Dauno-Double Trial: https://ash.confex.com/ash/2022/webprogram/Paper157126.html

Dr. Todd Lee breaking down the non-inferiority numbers: https://twitter.com/DrToddLee/status/1600662377250586627?s=20&t=RdIhJJpMG-G_oPUSH2u2mw

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WolverHeme Happy Hour – Détails, épisodes et analyse

Détails du podcast

Classements récents

Apple Podcasts

Liens partagés entre épisodes et podcasts

Qualité et score du flux RSS

Historique des publications

Derniers épisodes publiés

Podcasts Similaires Basées sur le Contenu

Apple Podcasts

Spotify

Podcasts Similaires Basées sur le Contenu

WolverHeme Happy Hour – Détails, épisodes et analyse

Détails du podcast

Classements récents

Apple Podcasts

Liens partagés entre épisodes et podcasts

Other73

PubMed40

Nature4

Qualité et score du flux RSS

Historique des publications

Derniers épisodes publiés

Podcasts et contenus similaires

Podcasts Similaires Basées sur le Contenu

Apple Podcasts

Spotify

Podcasts Similaires Basées sur le Contenu

Other73

PubMed40

Nature4