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Explorez tous les épisodes du podcast Unseen Upside: Investments Beyond Their Returns

Plongez dans la liste complète des épisodes de Unseen Upside: Investments Beyond Their Returns. Chaque épisode est catalogué accompagné de descriptions détaillées, ce qui facilite la recherche et l'exploration de sujets spécifiques. Suivez tous les épisodes de votre podcast préféré et ne manquez aucun contenu pertinent.

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TitreDateDurée
S6:E5 AI & Robotics: Shaping the Future of Work, Mobility, and Medicine16 Dec 202500:38:35

Step into the world of advanced robotics, where AI is transforming how we work, move, and live. 

Discover how surgical robots, autonomous vehicles, and AI-driven exoskeletons are advancing healthcare, streamlining operations, and restoring independence for individuals. Hear from innovators at Xeno Dynamics, leading investors, and a family whose journey with multiple sclerosis (MS) inspired a foundation dedicated to advancing exoskeleton rehabilitation, opening doors to greater autonomy and inclusion worldwide.

Guests include:

  • Maram Fakhouri, Vice Chair and Co-Founder of STF5 Care Foundation
  • Zhe Liang, Chairman of Xeno Dynamics
  • Lior Susan, Founder and Managing Partner of Eclipse Ventures
  • Judy Zhang, Head of China Client Business and Partner at Cambridge Associates

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S6:E4 AI & Agriculture: Data-Driven Fields, Resilient Futures02 Dec 202500:40:41

Travel to a Vermont dairy farm to see how AI is reshaping agriculture.

Learn how data-driven tools are making farming more sustainable and productive, and how companies like Inari Seeds are engineering crops for a changing climate. This episode uncovers the future of food—where technology, tradition, and environmental stewardship meet.

Guests include:

  • Lucas Mann, Co-Founder and Managing Partner of Acre Venture Partners
  • Catherine Feuillet, Chief Scientific Officer at Inari
  • Richard Nelson, Farmer at Nelson Dairy Farm

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S5:E4 Digital Health: Transforming Care, Improving Access19 Nov 202400:37:36

How will evolving digital technologies impact healthcare delivery, patient experience, and access to care?

According to new venture-backed companies, they can advance health equity, democratize access, and empower individuals to take control of their health journey. Alongside industry pioneers and investors, we explore digital health advancements such as telemedicine, remote monitoring, and data-driven diagnostics that are all working to improve healthcare efficiencies.

Join us as we uncover the potential of these technologies to improve healthcare outcomes for all.

Guests include:

  • Lynne Chou O'Keefe, Founder & Managing Partner at Define Ventures
  • Siva Namasivayam, CEO & Co-Founder at Cohere Health
  • Chavon Sutton, Senior Investment Director in the Sustainable & Impact Investing Research Group at Cambridge Associates


Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S5:E3 From Barriers to Bridges: Rural Health Access05 Nov 202400:40:33

Join us in Kotzebue, Alaska to explore the issue of rural healthcare and the inequities faced by these communities.

We shine a light on innovative solutions aimed at improving rural healthcare delivery, like a program called Siamit that’s connecting cutting-edge medicine from Massachusetts General Hospital (MGH) and Harvard Medical School to the tribal regions of Alaska. We also look at the role of venture capital in driving advancements that promote access to healthcare for those living in rural parts of the country.

Guests include:

  • Lucas Trout, Lecturer on Global Health and Social Medicine at Harvard Medical School
  • Susan Rawlings Molina, Co-Founder and CEO at GroundGame Health
  • Alyssa Jaffee, Partner at 7wireVentures


Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S5:E2 Drug Affordability: The High Cost of Healing22 Oct 202400:43:08

Prescription drug prices in the United States are 2.78 times higher than in other developed countries, but why?

We untangle the barriers surrounding drug affordability and find out why accessing life-saving medications is costly to so many. Joined by experts, advocates, and one Cystic Fibrosis patient relying on expensive medication to live, we examine the complex factors contributing to the high costs of drugs, from research and development to pricing strategies and supply chain dynamics. We also investigate potential solutions to improve access and affordability without compromising on drug innovation.

Guests include:

  • Peter Kolchinsky, Founder and Managing Partner at RA Capital
  • Gunnar Esiason, Head of Patient Engagement at RAVen (RA Ventures)
  • Dean Dimizas, Partner in the Private Client Practice at Cambridge Associates

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S5:E1 Investing in Affordable Homes for Healthier Communities08 Oct 202400:33:53

Join us as we head to the Bronx to examine the critical intersection of housing and health and the innovative solutions that are aiming to address the affordable housing crisis in major cities like New York and LA. Through conversations with non-profit leaders and impact investors, we dive into how affordable housing impacts public health and health equity, highlighting the investment strategies and community partnerships that are moving the needle. We also discuss the challenges of housing insecurity and the disproportionate effects on marginalized communities, recognizing affordable housing is a critical determinant of community health. 

Guests include:

  • Margaret Anadu, Senior Partner at The Vistria Group
  • Tim Ortez, Vice President & Chief Financial Officer at Weingart Foundation
  • Jasmine Richards, Head of Diverse Manager Research at Cambridge Associates

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company. Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S5:EP0 Unseen Upside - Season Five Trailer01 Oct 202400:03:01

How does venture capital contribute to advancing health equity and public health? Find out on season five of Unseen Upside, premiering Tuesday, October 8.

This season, we dive into how today's investment decisions are shaping tomorrow's innovations in critical areas such as affordable housing, maternal health, drug pricing, and more. Join us for engaging conversations with investors and entrepreneurs as we uncover the profound impact of venture capital on our lives on a grand scale.

Powered by the global network of Cambridge Associates, join us to explore healthcare investments beyond their returns.

Listen now to Unseen Upside

The Decision to Delegate14 Aug 202400:34:02

While we’re busy pulling together stories for the fifth season of Unseen Upside, we thought you might be curious about what it is that Cambridge Associates actually does. In a nutshell, we have the privilege of partnering with some of the world’s top institutional investors—like nonprofits, universities, hospitals, pension plans, and even private families—and we try to help them reach their investment goals.

Recently, we had a conversation with four of our non-profit clients from institutions with assets ranging from $200 million to $850 million to understand why they chose to outsource day-to-day portfolio decisions so they could focus on bigger picture strategy for their organizations. Their stories offer insight into how we collaborate with clients so they can do even more for the communities they serve. 

Don’t forget to check back this fall for the latest season of Unseen Upside: Investments Beyond Their Returns.

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company. Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S4:E6 AI & Healthcare: The Next Frontier16 Apr 202400:46:51

Artificial intelligence is transforming healthcare, unleashing new investment opportunities. From cancer screening to drug discovery, AI promises to augment clinical decision-making and improve care. 

We’ll explore the surging ecosystem of medical AI innovations, from the emerging tech landscape to practical deployment. But what are the challenges facing real-world implementation? Which applications show the most promise? 

Join us as we investigate how artificial intelligence can change healthcare for the better while examining what it will take to do it well. 

Guests include:

  • Bob Nelsen, Co-Founder and Managing Director at Arch Venture Partners
  • Daphne Koller, Founder and CEO at insitro
  • David Baker, Ph.D., 2024 Nobel Prize in Chemistry Laureate, Director at the Institute for Protein Design and Professor of Biochemistry at University of Washington
  • Theresa Hajer, Partner and Managing Director of Venture Capital Research at Cambridge Associates


Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company. Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S4:E5 Unlocking the Dark Genome for Lupus and Other Autoimmune Diseases02 Apr 202400:43:51

Autoimmune diseases like lupus impact over 5 million patients globally, but treatment options remain limited. Now, decoding the once mysterious "dark genome" could bring new therapies. Over 90% of our DNA was once considered "junk"—but we’ve learned this dark matter regulates gene expression and human disease. This episode takes you to the pioneers who are unlocking the dark genome's potential to correct root causes of complex conditions like lupus. We'll chat with those illuminating this uncharted territory and developing novel approaches. 

Guests include:

  • Rosana Kapeller, M.D., Ph.D., Co-Founder, President, & CEO at Rome Therapeutics
  • Steve Kafka, General Partner at S32
  • Keri Mastrogiacomo, mother of a Lupus patient
  • Katherine Cavanagh, Associate Investment Director at Cambridge Associates 

This episode has named a Winner by the International Women’s Podcast Awards for their “A Moment of Visionary Leadership” category.

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company. Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S4:EP4 Appetite for Change: The Obesity Epidemic Meets Biotech 19 Mar 202400:43:53

Obesity is a global health crisis, with over 650 million adults affected worldwide. This drives massive economic and disease burdens. Yet new treatment options like GLP-1 drugs offer hope. This episode analyzes the investment landscape and future of obesity therapeutics, focusing on transformational GLP-1 drugs like Ozempic that curb appetite. Join us as we investigate the promise and challenges of emerging anti-obesity drugs, learn about one patient’s journey taking them, and discover what the future of weight loss medicine could look like. You'll hear from leaders in the space as well as a current patient taking these medications. Guests include:

  • Rod Wong, Founder, Managing Partner, and Chief Investment Officer at RTW Investments
  • Raymond Stevens, Ph.D., Chief Executive Officer at Structure Therapeutics
  • Dean Dimizas, Partner and Managing Director at Cambridge Associates
  • Kathleen Mikaelian, Patient

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company. Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. 

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S4:EP3 Precision Oncology & Advancing Personalized Cancer Care05 Mar 202400:39:03

Precision oncology represents an exciting shift in cancer treatment from a one-size-fits-all approach to personalized care based on each patient's unique cancer and molecular makeup. In this episode, we'll explore how precision oncology is transforming the landscape of cancer care and improving outcomes at leading hospitals like St. Jude Children’s Research Hospital. We'll discuss the latest precision diagnostic technologies enabling doctors to analyze a tumor's molecular profile and match targeted therapies to save lives. Join us as we investigate the promise of precision medicine to make cancer treatment more effective and more equitable. Guests include:

  • Rick Shadyac, President and CEO at ALSAC, the fundraising and awareness organization for St. Jude Children’s Research Hospital, a Cambridge Associates client
  • Matt Gevaert, Co-Founder and Board Member at Kiyatec
  • Jason Robart, Co-Founder & Managing Partner at Seae Ventures
  • Jeff Blazek, Partner and Head of the Northeast & Midwest Endowment & Foundation Practice at Cambridge Associates, who works with ALSAC/St. Jude as one of his clients, in partnership with Anurag Pandit, CIO of ALSAC/SJCRH, and the Investment Department.

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company. Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. 

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S6:E3 AI & Biotech: Accelerating Breakthroughs in Medicine18 Nov 202500:32:25

Venture into the world of AI-driven drug discovery, where new models are making the process faster, safer, and more ethical.

Discover how Axiom’s pioneering technology is helping to eliminate the need for animal model testing, paving the way for more humane and effective drug development. Hear from leaders at Cleveland Clinic and Amplify about how AI is transforming healthcare for patients and providers alike.

Guests include:

  • Stefan Strein, Chief Investment Officer at Cleveland Clinic
  • Brandon White, Co-Founder of Axiom
  • Sunil Dhaliwal, Founder and General Partner at Amplify Partners

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S4:EP2 Living Longer But Losing Our Minds: The Alzheimer's Emergency20 Feb 202400:40:50

Thanks to medical advances, we're living longer lives but with that comes rising rates of Alzheimer's disease. Currently 6 million Americans have Alzheimer's, and that could triple by 2050. This episode explores emerging innovations offering hope against neurodegenerative diseases. We'll discuss promising new drugs that could slow cognitive decline and the strides scientists are making towards understanding causes and developing therapies—and how these breakthroughs are giving hope to one family fighting to save their mom. 

Episode two explores the history of Alzheimer’s, its current challenges, and the promising therapies made possible by innovation and investment. You’ll hear from:

  • Dr. Asa Abeliovich, Neurologist, Molecular Geneticist, and Founder and CEO at Leal Therapeutics
  • Carl Gordon, Managing Partner and Head of Global Private Equity at OrbiMed
  • Ham Lee, Co-Head of the Healthcare Practice at Cambridge Associates
  • Randi Casciano, Director of Global Public Relations at Cambridge Associates

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company. Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. 

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S4:EP1 Mind Matters: Making Sense of the Mental Health Crisis06 Feb 202400:30:27

The mental health crisis is growing, especially among Gen Z (91% report anxiety or depression). This episode explores innovations in mental healthcare access, new therapeutic approaches for young people and families, and how hospitals are striking creative partnerships to tackle this emergency. Tune in to learn what’s working and showing promise in mental healthcare, glimpses of what the future could look like, and where persistent gaps remain. Hear from leaders Melody Dickerson (VHC Health); Emily Melton (Threshold Ventures); Naomi Allen (Brightline); and Bridget Sproles (Cambridge Associates).

S4:EP0 Unseen Upside - Season Four Trailer30 Jan 202400:03:27

The future of healthcare is here. Get an an inside look at the innovations transforming lives on season four of Unseen Upside, premiering Tuesday, February 6.

This season, we pull back the curtain on cutting-edge advancements at the intersection of technology and medicine, learn how AI is revolutionizing diagnostics and treatment, discover the potential of GLP-1s to combat obesity, and how breakthrough Alzheimer's therapies are offering hope to millions. We'll also uncover creative approaches to solving the mental health crisis.

Powered by the global network of Cambridge Associates, join us to explore healthcare investments beyond their returns.

S3:EP5 Can Deep Tech Combat Fast Fashion?30 May 202300:35:46

The fashion industry accounts for up to 10% of global carbon dioxide output and roughly 2.6 million tons of clothing returns end up in US­­­ landfills each year instead of being resold. Meanwhile, the shipping for these returns account for around 16 million tons of CO2 emissions—and fast fashion is making things worse. But what if deep tech could help to cut down on returns? Amid the rise of conscious consumerism, one company is using video game technology and AI generated avatars to help online shoppers try on clothing virtually before they buy, in the hopes of making the fashion industry more sustainable. We’ll learn more from Christine Marzano (BODS); Carle Stenmark (VMG Partners); Jennifer Varekamp (MassArt); and Annachiara Marcandalli (Cambridge Associates).

S3:EP4 Battery Storage, Renewable Energy & Building a Sustainable Grid16 May 202300:37:30

More than two-thirds of our electricity is generated by burning fossil fuels, a major climate change contributor. As such, use of renewable energy is expected to double in the next 15 years. But there’s a catch: the power they generate depends on variable factors like wind and sun, making them too unreliable to power our grid. However, recent battery innovations could be the solution. One company has developed an iron-air battery capable of storing energy for multiple days, which may be the missing link needed to decarbonize our grid for good. Join us to learn more from Mateo Jaramillo and Jocelyn Newhouse (Form Energy); Dipender Saluja (Capricorn Investment Group); Anders Lyngaa Kristoffersen (The Velux Foundations); and Di Tang (Cambridge Associates).

S3:EP3 eVTOLs & Flying Cars27 Apr 202300:30:59

Humans have fantasized about flying cars for decades, but they’ve yet to leave the pages of our sci-fi books...or have they? Join us as we visit Joby Aviation out in Marina, California to witness their eVTOL (electric vertical take-off and landing) aircraft take flight. With plans to operate like ubers in the sky, eVTOLs are the closest thing we have to flying cars—and they could be a commercial reality by 2025. The companies creating them promise a faster and greener mode of transportation, but who’s investing in them? Are they safe? And how will they change our transportation infrastructure? We’ll discuss these questions and more with Eric Allison (Joby Aviation); Andrew Beebe (Obvious Ventures); and Doug Carlson and Alex Innes-Whitehouse (pilots affiliated with Cambridge Associates).

S3:EP2 CRISPR, Dodo Birds, Woolly Mammoths & Gene Editing11 Apr 202300:39:10

According to scientists, 30,000 species per year are being driven towards extinction and 50% of all species could be extinct by 2050 due to climate change. But what if there was something we could do, in addition to conservation, to change this trajectory? That’s what the scientists and engineers at Colossal Biosciences are working towards: reversing extinction. Using CRISPR and advanced gene editing techniques, they plan to bring back the woolly mammoth and the dodo bird to help combat climate change and complement existing conservation efforts. Join us to discuss this topic with Ben Lamm (Colossal Biosciences); Tom Chi (At One Ventures); and John Calvelli (Wildlife Conservation Society).

S3:EP1 Will Fusion Power (or "Stars in a Jar") Replace Fossil Fuels?28 Mar 202300:32:22

Harnessing fusion power has been an elusive goal of physicists and researchers for decades. However, recent scientific advances are helping to make that goal a reality. Described as a star in a bottle, fusion is what powers our sun and stars, offering us the prospect of limitless clean energy. But here on earth, it has presented unresolved engineering challenges—until now. Commonwealth Fusion Systems is on the brink of delivering commercial fusion energy thanks to their revolutionary magnet. But how does a safe, limitless, carbon-free, fusion power plant operate? What does it look like? How and when will this technology be replicated to meet the world’s energy needs? We’ll learn more from Bob Mumgaard (Commonwealth Fusion Systems); Katie Rae (The Engine); and Theresa Hajer (Cambridge Associates).

S3:EP0 Unseen Upside - Season Three Trailer20 Mar 202300:02:10

Season three of Unseen Upside: Investments Beyond Their Returns by Cambridge Associates explores the innovations turning science fiction to fact and the people investing in them. Powered by the global network of Cambridge Associates, discover the investments being made that will redefine our future. Join us to uncover the Unseen Upside.

S2:EP5 Space: Zero Gravity Space Factories14 Jun 202200:40:57

We’ve all dreamt of traveling to outer space and recently, that dream has been more tangible than ever. But for those of us without a seat on the next rocket, how will space innovation improve our lives here on Earth? It turns out that the microgravity environment of orbit provides manufacturing capabilities that aren’t possible on earth. It allows us to create things—think artificial organs, life-saving pharmaceuticals, fiber optic cables, and other products—that are superior to those created on our planet. In this episode, we explore the growing Space Economy with Delian Asparouhov (Varda/Founders Fund); Tess Hatch (Bessemer Venture Partners); Alex Readey (Cambridge Associates); and a seven-year-old aspiring astronaut.

S6:E2 AI & Geothermal: The Next Wave of Clean Energy04 Nov 202500:38:20

What happens when AI meets the earth’s natural heat?

Join us as we explore how Fervo and global partners are harnessing AI to unlock geothermal energy’s potential—delivering clean, flexible power around the clock. From Houston to the Middle East, we examine the science, policy, and investment trends driving the energy transition, and how geothermal could help power the AI revolution itself.

Guests include:

  • Fahad Alajlan, President at King Abdullah Petroleum Studies and Research Center (KAPSARC)
  • Josh Posamentier, Co-Founder and Managing Partner of Congruent Ventures
  • Tim Latimer, Co-Founder and CEO of Fervo Energy
  • Tom Mitchell, Partner at Cambridge Associates

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S2:EP4 Water: Carbon Sinking Kelp Farms02 Jun 202200:40:16

Oceans make up 72% of the earth’s surface and have absorbed around 40% of carbon emissions since 1840. As such, investors are increasingly putting capital to work in ocean-based businesses to both mitigate climate change and enhance the Blue Economy—but how? In this episode, we visit Running Tide in Portland, ME to see this concept in action. They use advanced aquatic growing systems and data science to grow shellfish and kelp forests. The result? A highly nutritious, sustainable protein and a natural carbon removal system. Join us to dissect this topic with Marty Odlin and Adam Baske (Running Tide); Marc von Keitz (Grantham Foundation for Protection of the Environment); Sidney McLaurin (Material Impact); and Sarah Edwards (Cambridge Associates).

S2:EP3 Fire: Net-Zero Plasma Diamonds17 May 202200:38:48

Fire is often a marker associated with the worst effects of climate change. But what if fire could actually be harnessed to help reverse it? In this episode, we meet Diamond Foundry, a company revolutionizing the diamond industry with their affordable, lab-created diamonds—free from the myriad of problems associated with the mining process. We’ll learn about the social and environmental impacts of this exploding industry and how investors are rethinking the carbon footprints of their portfolios. We’ll hear from Mona Akhavi (Diamond Foundry); James Joaquin (Obvious Ventures); Dame Caroline Mason (Esmee Fairbairn Foundation); and Simon Hallett (Cambridge Associates).

S2:EP2 Air: Planting 20M Trees by 203003 May 202200:39:04

For most of human history, we’ve been cutting down trees. However, the acceleration of carbon credit markets and the societal demand for climate solutions are pushing us to re-think our relationship with them. So how can investors earn a compelling return from planting trees while helping to sequester carbon and increase biodiversity? We’ll travel to Broadclyst, England to experience the innovation surrounding reforestation and how one organization has the lofty goal of planting 20 million trees in less than 10 years. We’ll hear from Mark Wishnie (BTG Pactual); Peter Vermeulen (The National Trust); Phillip Smart (The Killerton Estate); and Annachiara Marcandalli (Cambridge Associates).

S2:EP1 Earth: Mushrooms and the Future of Meat19 Apr 202200:36:21

Livestock take up nearly 80% of global agricultural land yet produce only 20% of the world’s supply of calories—so how can we make feeding people more efficient? In this season two premiere of Unseen Upside, we visit an alternative protein company in Boulder, Colorado called Meati. There, we explore how a nutrient-rich fungi called mycelium is changing the game when it comes to protein consumption. It’s better for people and the planet—yet somehow doesn’t compromise on flavor. We’ll learn about the future of nutritional ecosystems from Sam Kass (Acre Venture Partners); David Chang (Momofuku); Tyler Huggins (Meati); and Chavon Sutton (Cambridge Associates).

S2:EP0 Unseen Upside - Season Two Trailer11 Apr 202200:02:47

Season two of the Unseen Upside podcast by Cambridge Associates explores elements of our natural world—and beyond—with the innovators and investors aiming to enhance and protect our future. Powered by the global network of Cambridge Associates, host Luke Charest will explore the investments being made that will improve our lives in unexpected ways. Join us to uncover the Unseen Upside.

S1:EP5 Consumer Brands: Why Do We Buy?16 Nov 202100:23:11

Consumers are demanding more from brands than ever before, but how are brands rising to the occasion? In this episode of Unseen Upside, Cambridge Associates’ Global Head of Private Investments, Andrea Auerbach, looks at how technology, coupled with evolving consumer preferences, are impacting how both startups and incumbent brands market themselves. We also speak with Jenny Gyllander, Founder of Thingtesting and Robin Tsai and Wayne Wu, both General Partners at VMG Partners.

S1:EP4 Digital Health: How Is Tech Revolutionizing Healthcare?02 Nov 202100:34:10

In this episode of Unseen Upside, we look at how technology is transforming healthcare for both the provider and the patient—and making it more equitable. Sami Inkinen, CEO and Co-Founder of Virta Health will discuss how his company is treating and reversing diabetes through an app on your phone. We also speak with Jasmine Richards, Cambridge Associates' Head of Diverse Manager Research; Tuoyo Louis, Co-Founder of Seae Ventures; and Rochelle Witharana, CFO of The California Wellness Foundation.

S1:EP3 Crypto: How Are Artists Leveraging NFTs?20 Oct 202100:30:56

In this episode of Unseen Upside, we’ll explore how non-fungible tokens (NFTs)—and the blockchain technology that supports them—are enabling a revolution in how artists and creators earn a living. You’ll hear from Cambridge Associates’ Joe Marenda and Kenneth Tom; Dawn Harflinger, President & CEO of Queen Lili`uokalani Trust in Hawaii; Maria Shen, Partner at Electric Capital; and Cooper Ray, a photographer based in New York City.

S1:EP2 Digital Infrastructure: Where Does the Internet Come From?28 Sep 202100:23:48

Now more than ever, we rely on high-speed internet to power our work and personal lives—but where does it come from? In this episode of Unseen Upside, we visit Cambridge Associates’ Minesh Mashru in Amsterdam to discuss digital infrastructure and the investments being made in fiber optic cables. We’ll also meet Simon Soder, a Partner at Antin Infrastructure Partners in Paris, Aaron Werley, Vice President of Architecture & Engineering at Zayo Group, and Andrew Kwok, the CEO of HGC Global Communications in Hong Kong.

S1:EP1 Impact Investing: How Is Tech Making Food Systems More Sustainable?14 Sep 202100:38:01

In this season one premiere of Unseen Upside, we take you to the Foster Brothers Dairy Farm in Middlebury, Vermont to explore impact investing through the lens of precision agriculture and sustainable farming—and specifically, how technology is changing food systems for the better. In this episode, we talk with farmers George and Jeremy Foster, Sam Kass, a Partner at Acre Venture Partners and the former Obama White House Chef, Liqian Ma, Head of Sustainable and Impact Investing at Cambridge Associates, and Noelle Laing, Managing Director of Impact Investing for a private family office.

S6:E1 AI & Education: Investing in the Future of Learning21 Oct 202500:40:43

Discover how AI is breaking down barriers to education and tailoring learning experiences for students everywhere.

From Duolingo’s global reach to the innovative use of AI in real classrooms at Miss Porter’s School in Connecticut, this episode explores how technology is expanding access, enhancing engagement, and equipping the next generation with essential skills—while ensuring integrity and safety remain at the forefront.

Guests include:

  • Luis von Ahn, CEO and Co-Founder of Duolingo
  • Henry Ellenbogen, Chief Investment Officer at Durable Capital Partners
  • Maureen Lamb, Latin teacher and the Language Department Chair at Miss Porter's School
  • Dean Dimizas, Partner and Managing Director at Cambridge Associates

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S1:EP0 Introducing Unseen Upside30 Aug 202100:01:55

Cambridge Associates’ inaugural podcast season explores the tech changing our daily lives and the people who invest in it. How we invest today drives tomorrow’s innovations. Through conversations with investors and early adopters, explore how investment decisions have the potential to improve our daily lives in unexpected ways. Powered by the network of Cambridge Associates, host Luke Charest will explore the investments being made that will redefine our future. Join us to uncover the Unseen Upside.

S6:EP0 Unseen Upside - Season 6 Trailer14 Oct 202500:03:43

Get ready—Season 6 of Unseen Upside launches October 21.

This season, we’re taking you behind the scenes to explore how AI is transforming our world. From labs and classrooms to clinics and fields, we’ll follow the capital and uncover how AI is driving the next chapter of human progress.

Tune in for episode one on your favorite podcast platform, Tuesday, October 21.

S5:E8 Mini Episode | The Story of Saving the American Bison03 Oct 202500:09:58

Once numbering in the tens of millions, the American bison was nearly driven to extinction by the early 1900s. But a coalition of conservationists, Native American communities, and private partners were determined to save the species.

Join us for this mini episode of Unseen Upside: Investments Beyond Their Returns, as we share the remarkable story of the bison’s restoration alongside John Calvelli, Executive Vice President of Public Affairs at Wildlife Conservation Society.

Stay tuned for Season 6 which explores the transformative impact of AI across industries—launching Tuesday, October 21. In the meantime, catch up on past episodes in our podcast feed!


Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S5:E7 Mini Episode | What Inspires Our Guests: Must-Read Books and Podcasts, Pt 227 Aug 202500:05:20

Summer isn't over just yet--Unseen Upside is bringing you Part 2 of our summer reading list!

Tune in as we share more book recommendations from investors and entrepreneurs on the leading edge of healthcare.

Check the show notes for links to all the recommendations, and catch up on past episodes in our podcast feed. Stay tuned for Season 6—launching soon.

Featured Recommendations:

Guests Include:

  • Theresa Hajer, Head of US Venture Capital Research at Cambridge Associates
  • Alyssa Jaffe, Partner at Seven Wire Ventures
  • Lucas Trout, Lecturer on Global Health and Social Medicine at Harvard Medical School


Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S5:E6 Mini Episode | What Inspires Our Guests: Must-Read Books and Podcasts, Pt 127 Jun 202500:06:28

As summer heats up, Unseen Upside brings you a special two-part mini-episode packed with inspiration for your reading and listening list. From thought-provoking explorations of social justice and capitalism to the latest in women’s sports and business innovation, this short episode is your guide to what’s fueling the minds and spirits of those driving change in healthcare, housing, and beyond.

Whether you’re looking for your next great read, a podcast to spark new ideas, or just want to know what’s on the radar of industry leaders, this episode has you covered. Check the show notes for links to all the recommendations, and stay tuned for part 2 of our guests' summer picks soon!

Featured Recommendations:

Guests Include:

  • Chavon Sutton, Managing Director, Sustainable & Impact Investing at Cambridge Associates
  • Lynne Chou O’Keefe, Founder and Managing Partner at Define Ventures
  • Tim Ortez, Chief Financial Officer of the Weingart Foundation
  • Margaret Anadu, Senior Partner at The Vistria Group
  • Jasmine Richards, Head of Diverse Manager Research at Cambridge Associates
  • Gunnar Esiason, Head of Patient Engagement at RAVen (RA Ventures)
  • Dean Dimizas, Partner in the Private Client Practice at Cambridge Associates


Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S5:E5 The Maternal Health Crisis: Investing for Change03 Dec 202400:45:45

There’s a maternal health crisis in the United States, with high rates of maternal mortality, especially among marginalized communities. But what is being done to improve it? 

Through conversations with those on the front lines, we uncover the stark health inequities that exist in maternal healthcare and the developments created to tackle them. We also hear from mothers who have firsthand experience with Preeclampsia—a serious pregnancy complication and one of the many causes of maternal mortality— and one company on a quest to cure it.  

Guests include:

  • Scott Gottlieb, MD, Partner at New Enterprise Associates and Former FDA Commissioner
  • Scott Johnson, MD, Chief Executive Officer and Co-Founder at Comanche Biopharma
  • Jennell Lynch, Chief Executive Officer and Founder at Executive Doula Agency 
  • Theresa Hajer, Head of US Venture Capital Research at Cambridge Associates


Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

S6:E7 The Portfolio Behind Pearl: Funding a 100-Year Vision29 May 202600:36:25

What does it take to build something that lasts for generations?

In this special crossover episode from Cambridge Conversations, we explore how bold vision, patient capital, and a deep commitment to community helped transform San Antonio’s Pearl district from a shuttered brewery into a thriving destination.

Host Willis Wilson hands the mic to Unseen Upside host Hillary Ribaudo, who travels to San Antonio to speak with Bryant Ambelang, CEO of Silver Ventures (CA client); Shawn Hatter, President of Oxbow Development Group; and Mary Jo Palermo, Partner at Cambridge Associates.

Together, they unpack how a family’s commitment to place, culture, and community helped shape a “100-year business,” and what it takes to support that vision through market cycles, development challenges, and changing needs over time.

You’ll hear:

  • How Pearl evolved from a historic brewery into a thriving mixed-use destination
  • Why patient capital and long-term thinking were critical to its success
  • How liquidity, risk, and portfolio decisions helped support an ambitious vision
  • What investors can learn from building for both community impact and lasting value

Cambridge Conversations and Unseen Upside are developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.

S6:E6 Women, Wealth, and Economic Growth05 Mar 202600:37:51

Step into a conversation about the power of investing in women—and the ripple effects that follow.

This International Women’s Day, discover how closing the gender gap in leadership and capital unlocks new opportunities, fuels economic growth, and strengthens communities. This discussion goes beyond the numbers; it highlights the stories, challenges, and progress that emerge from supporting women at every stage. It's not just about building equity; it’s about creating a stronger future for everyone.

Guests include:

  • Ali Hogan, Founder & Board Chair of Rung for Women (CA Client)
  • Jenny Abramson, Founder & Managing Partner of Rethink Impact
  • Mary Jo Palermo, Partner at Cambridge Associates

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm with 50+ years of institutional investing experience. We partner with private clients, endowments, foundations, pension plans, and corporations to design and manage custom portfolios focused on generating alpha and achieving investment objectives. Our services include discretionary and advisory portfolio management, staff extension, and alternative asset class mandates.

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