Explorez tous les épisodes du podcast This Week in Neuroscience
| Titre | Date | Durée | |
|---|---|---|---|
| TWiN 65: Air pollutants promote dementia | 04 Nov 2025 | 01:37:18 | |
TWiN explains epidemiological data showing that exposure to air pollution was associated with an increased risk of developing Lewy body dementia, and nasal administration of air pollution in mice led to brain atrophy and impaired cognition and motor function. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 64: How the brain decides what we see | 08 Oct 2025 | 01:14:01 | |
TWiN explains how visual neurons show functional flexibility by selectively responding to subsets of inputs representing attended objects while ignoring those conveying information about irrelevant objects. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 55: A brain circuit for day/night balance | 28 Oct 2024 | 01:09:29 | |
TWiN explains the identification of a brain circuit and periodic branch-specific neurotransmitter deployment that regulates organismal adaptation to photoperiod change. Hosts: Vincent Racaniello, Jason Shepherd, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 54: How pregnancy transforms the brain | 01 Oct 2024 | 01:05:25 | |
TWiN explores how pregnancy leads to modifications in brain structure and function that may prepare the mother for parenting. Hosts: Vincent Racaniello, Jason Shepherd, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 53: Slowing time by cooling the brain | 29 Jul 2024 | 01:10:03 | |
Joseph Paton and Felipe Rodrigues join TWiN to explain how they used temperature manipulation to alter the speed of neuronal dynamics in the dorsal striatum of rats, a manipulation that selectively slowed down or sped up time perception, illuminating the mechanisms of time-based decisions. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Guest: Joseph J. Paton and Felipe Rodrigues Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 52: Probiotic improves social behavior in children with ASD | 24 Jun 2024 | 01:05:50 | |
Mauro Costa-Mattioli returns to TWiN to discuss the results of a placebo controlled, double blind clinical trial of a probiotic which improved social behavior but not autism severity in children with ASD. Hosts: Jason Shepherd, Timothy Cheung, and Vivianne Morrison Guest: Mauro Costa-Mattioli Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 51: Sensory processing dysfunction in autism spectrum disorders | 28 May 2024 | 01:11:20 | |
TWiN reviews altered somatosensory reactivity, which is frequently observed among individuals with autism spectrum disorders (ASD), and in mouse models the developmental timing of aberrant touch processing can predict the manifestation of ASD-associated behaviors in mouse models. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 50: Neurological sequelae after COVID-19 | 29 Apr 2024 | 01:04:25 | |
TWiN reviews experiments which show that SARS-CoV-2 triggers the up-regulation of synaptic components and perturbs local electrical field potential in cerebral organoids, organotypic culture of human brain explants and post-mortem brain samples from individuals with COVID-19. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 49: Mirror, mirror on the wall, who's the fairest mouse of all? | 25 Mar 2024 | 01:31:25 | |
TWiN welcomes mice to the elite club of 'self-aware' animals, with a study demonstrating a mirror-induced self-directed behavior in mice resembling visual self-recognition. Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 48: Traumatic brain injury and retroviruses | 19 Feb 2024 | 00:51:13 | |
TWiN describes a study that reveals activation of endogenous retroviruses in oligodenroglia from patients with traumatic brain injury. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 47: Walking after spinal cord injury | 29 Jan 2024 | 00:55:25 | |
TWiN explains an amazing study of a man who was paralyzed after a spinal cord injury and regained the ability to walk after implantation of a brain-spinal cord interface. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 46: Neuronal activity promotes glioma progression | 01 Jan 2024 | 00:51:04 | |
TWiN explains research showing that interaction between glioma cells and neurons in the brain shares mechanistic features with synaptic plasticity that contributes to memory and learning in the healthy brain. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 63: Microbiome-targeted neurotherapy | 21 Aug 2025 | 01:31:51 | |
TWiN discusses research showing that Lactobacillus acidophilus promotes cognitive function recovery after cerebral ischemia, by regulating microglial peroxisomal function. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim CheungSubscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 45: Acupuncture modulates the immune system | 13 Dec 2023 | 00:52:24 | |
TWiN discusses research showing that sciatic nerve activation with electroacupuncture at the sciatic nerve controls systemic inflammation and rescues mice from polymicrobial peritonitis, by inducing vagal activation of aromatic L-amino acid decarboxylase, leading to the production of dopamine in the adrenal medulla. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 44: ADHD and persistent pain | 02 Nov 2023 | 01:00:41 | |
TWiN reviews a mouse model of ADHD to characterize hypersensitivity to pain, and that sensitization is further amplified in a pathological inflammatory state. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 43: Pavlovian opioid tolerance | 04 Oct 2023 | 01:02:41 | |
TWiN discusses a study of on the pathways that control opioid analgesic tolerance, a root cause of opioid overdose and misuse, which can develop through an associative learning. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 42: Therapeutic effects of psychedelic drugs | 18 Jul 2023 | 00:56:34 | |
TWiN explains how psychedelic drugs such as LSD, psilocybin, and MDMA, which are being explored for treating a wide range of neuropsychiatric diseases, reopen the social reward period for critical learning. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Click arrow to play
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 41: Alzheimer's and melanin-concentrating hormone | 20 Jun 2023 | 01:18:30 | |
Vivianne explains how early in Alzheimer's disease, the brain attempts to counteract the increased excitatory drive caused by amyloid deposition, and that melanin-concentrating hormone, produced during sleep, is involved in this protective response. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 40: Dopamine organizes behavior's syllables | 11 May 2023 | 01:04:17 | |
Tim takes TWiN through two studies on the role of dopamine: that syllables are natural units of spontaneous behavior used by the brain to structure action, and that mesolimbic dopamine release conveys causal associations but not reward prediction errors, thereby challenging the dominant theory of reward learning. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 39: Virus-like capsids trigger paraneoplastic disease | 28 Apr 2023 | 00:52:39 | |
Junjie from Jason's lab joins TWiN to discuss the observation that the cell gene PNMA2 encodes non-enveloped virus-like capsids that induce autoantibodies which underlie paraneoplastic syndrome. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Junjie Xu Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 38: Bacterial immunity heals sensory neurons | 27 Mar 2023 | 01:04:57 | |
TWiN explains the finding that immunity to commensal bacteria promotes sensory neuron regeneration via the cytokine interleukin-17A. Hosts: Vincent Racaniello, Ori Lieberman, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 37: Microglia at the crossroads | 23 Jan 2023 | 01:15:05 | |
TWiN reviews the field of microgial research, which has advanced in recent decades but is constrained by nomenclature that is necessary but often implies specific functions. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 36: Unbearable neurologists | 03 Jan 2023 | 01:29:33 | |
TWiN answers listener questions about Alzheimer's disease, glaucoma and the microbiota, Dravet's Syndrome, schizophrenia, brain development, and chips implanted in the human brain. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 62: Memories of bad food | 23 Jul 2025 | 01:21:48 | |
TWiN explains research which identifies the regions of the brain that register a long-lasting aversion to potentially poisonous food even with meal to illness delays of several days. Hosts: Vincent Racaniello, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 35: Neuromodulation in treatment-resistant depression | 06 Dec 2022 | 01:09:13 | |
Jason and Tim review the use of an implanted chronic deep brain sensing and stimulation device to carry out biomarker-driven closed-loop therapy that resulted in a rapid and sustained improvement in depression. Hosts: Jason Shepherd and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 34: Microglia vital after spinal cord injury | 30 Sep 2022 | 01:09:17 | |
TWiN explains how central nervous system resident macrophages known as microglia coordinate cellular interactions during spinal cord repair in mice. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 33: Viruses leaving the brain | 31 Aug 2022 | 00:58:11 | |
TWiN describes how neurotropic viruses leave the brain via meningeal lymphatic vessels located dorsally and basally beneath the skull. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 32: Relearning how to move after stroke | 02 Aug 2022 | 00:59:47 | |
TWiN reviews how, in a mouse stroke model, recovery of movement is associated with the remaining cortex and the striatum coordinating their activity together. Hosts: Ori Lieberman, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 31: HIV-1 co-receptor shapes window for memory linking | 29 Jun 2022 | 01:11:52 | |
TWiN explains the observation that in mice, the HIV-1 co-receptor CCR5 closes the temporal window for linking different memories. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 30: Gut to brain spread of alpha-synuclein in Parkinson's disease | 24 May 2022 | 01:09:52 | |
TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a pathologic form that spreads to the brain and leads to features of Parkinson's disease. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 29: Astrocytes close the critical period | 02 May 2022 | 01:02:05 | |
TWiN explains the finding that in the mouse visual cortex, astrocytes are key elements in the experience-dependent wiring of brain circuits. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 28: Oligodendrocyte performance enhancing exosomes | 04 Apr 2022 | 01:13:59 | |
TWiN reveals how oligodendrocytes enhance axonal energy metabolism by transcellular delivery of a protein, SIRT2, that deacetylates mitochondrial proteins. Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison Click arrow to play Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 27: Eyes wired to the auditory cortex | 03 Mar 2022 | 01:03:47 | |
TWiN discusses the finding that rewiring retinal projections to the auditory thalamus in ferrets leads to visually responsive cells that are typical of cells in the visual cortex. Hosts: Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 26: Immunological memory in the brain | 31 Jan 2022 | 00:53:49 | |
TWiN reviews evidence in mice that brain neurons encode and retrieve specific immune responses. Become a patron of TWiN! Links for this episodeMusic is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 61: Blood to the brain | 25 Jun 2025 | 01:40:12 | |
TWiN reveals that proteins travel from the blood to the brain where they are taken up by microglia, revealing a new mode of communication between the brain and the periphery. Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 25: Thanks for listening | 28 Dec 2021 | 01:02:44 | |
TWiN answers listener questions on sex in neuroscience studies, rotating memories in the brain, odorant receptors in the brain, and neutrophils that promote neuron survival. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 24: Social transmission of maternal behavior with Ioana Carcea and Robert Froemke | 24 Nov 2021 | 01:12:47 | |
Ioana and Robert join TWiN to discuss their work demonstrating that rodents acquire maternal behavior by social transmission from an experienced mother to a virgin female how to care for a litter via endogenous oxytocin. Hosts: Vincent Racaniello and Timothy Cheung Guests: Ioana Carcea and Robert Froemke Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe | |||
| TWiN 23: Peripheral nervous system with Bruce Carter | 31 Oct 2021 | 01:11:20 | |
Bruce Carter joins TWiN to discuss the peripheral nervous system: the development of nerves that convey sensory information like touch from the tips of your toes to the brain, and Schwann cells, which are necessary for ensuring that those sensory signals are sustained as they travel long distances to the brain. Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison Guest: Bruce Carter Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 22: It's never lupus | 29 Sep 2021 | 01:08:17 | |
TWiN explains how anti-DNA antibodies present in lupus patients bind to GluN2A-containing NMDA receptors, act as positive allosteric modulators, and impair spatial memory. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 21: How do we know if a mouse is hallucinating? | 24 Aug 2021 | 01:28:02 | |
TWiN explores a study of hallucination-like perception in mice which supports the idea that hallucinations arise as faulty perceptual inferences due to elevated dopamine in the striatum. Hosts: Vincent Racaniello, Ori Lieberman, and Timothy Cheung Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 20: Drifting aromas in the brain | 14 Jul 2021 | 01:18:08 | |
While perceptual constancy requires the brain to maintain a stable representation of sensory input, TWiN explores a study showing that odor-evoked responses in the olfactory cortex drift over periods of days to weeks. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 19: Glia 101 | 21 Jun 2021 | 01:12:54 | |
On this episode, Vivianne gives a primer on glial cells, with the goal of thinking about the central nervous system holistically and appreciating the different cell types that contribute to its function. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 18: Autism and the gut microbiome with Mauro Costa-Mattioli | 12 May 2021 | 01:10:52 | |
Mauro Costa-Mattioli joins TWiN to discuss how his laboratory dissects the contribution of host genetics and the microbiome in complex neurodevelopment disorders such as autism spectrum disorders. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Guest: Mauro Costa-Mattioli Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 17: Worms see the light with Michael Nitabach | 21 Apr 2021 | 01:21:59 | |
Michael Nitabach joins TWiN to discuss the finding that the nematode C. elegans, which do not have eyes, can discriminate between colors to guide foraging decisions and move them away from harmful bacteria that produce a blue-pigment toxin. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Guest: Michael Nitabach Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 15: Microbiome and neurodevelopment with Helen Vuong | 17 Feb 2021 | 00:49:33 | |
Helen joins TWiN to discuss her work on understanding how the maternal microbiome modulates fetal neurodevelopment in mice. Hosts: Ori Lieberman, Andres Bendesky, Jason Shepherd, and Vincent Racaniello Guest: Helen Vuong Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 60: You get the gist of it? | 03 Jun 2025 | 01:05:21 | |
TWiN discusses experiments which show that high-fidelity memories that lose their precision with time depends on reorganization of hippocampal circuitry. Hosts: Vincent Racaniello, Jason Shepherd, and Tim CheungSubscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 14: Reducing Alzheimer-like pathology in mice | 14 Jan 2021 | 01:10:52 | |
Ori, Jason, and Vincent discuss the use of antibodies to neutralize amyloid-β seeds before their deposition becomes detectable in transgenic mice, and the finding that the preclinical phase of Alzheimer's disease may be a late manifestation of earlier pathogenic seed formation. Hosts: Ori Lieberman, Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 13: mRNAs for long-term memory | 15 Dec 2020 | 01:08:29 | |
Ori, Jason, Erin, and Vincent dissect a study that utilizes single-cell RNA sequencing to reveal the genes that underlie remote memory storage in the medial prefrontal cortex of the mouse. Hosts: Ori Lieberman, Erin Calipari, Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 12: A gene for short-term memory | 11 Nov 2020 | 01:12:57 | |
Ori, Jason, and Vincent reveal identification of an orphan receptor that modifies short-term memory in mice, and a mouse model of COVID-19 that includes anosmia or loss of smell. Hosts: Ori Lieberman, Vincent Racaniello, and Jason Shepherd Subscribe (free): iTunes, Google Podcasts, RSS, emailBecome a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||
| TWiN 11: A dollar per neuron | 14 Oct 2020 | 01:06:21 | |
Maria joins TWiN to explain how single-cell transcriptomics is being used to reveal the evolution of the brain, at a cost of about $1 per neuron. Hosts: Ori Lieberman, Andres Bendesky, and Vincent Racaniello Guest: Maria Tosches Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode
Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv | |||