Explorez tous les épisodes du podcast This Week in Nephrology

Hi, This Week in Nephrology, we will be discussing article published in  October  issues of the Nephrology journals.

 Journal of the American Society of Nephrology

The Number and Size of Individual Kidney Medullary Pyramids is Associated with Clinical Characteristics, Kidney Biopsy Findings, and CKD Outcomes among Kidney Donors

Clinical journal of the American Society of Nephrology

Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy

Performance Characteristics of Candidate Criteria for Hemodialysis Arteriovenous Fistula Maturation

Nephrology dialysis transplantation  

High rates of psychological distress, mental health diagnoses and suicide attempts in people with chronic kidney disease in Ireland

Sex difference in cardiovascular risk in patients with chronic kidney disease: pooled analysis of four cohort studies

Kidney international  

A prospective controlled, randomized clinical trial of kidney transplant recipients developed personalized tacrolimus dosing using model-based Bayesian Prediction

American journal of kidney diseases  

Patient and Health Care Professional Perspectives on Addressing Obesity in ESKD

Clinical kidney journal 

High exposure to tacrolimus is associated with spontaneous remission of recurrent membranous nephropathy after kidney transplantation

The coexistence of diabetic retinopathy and diabetic nephropathy is associated with worse kidney outcomes 

Evaluation of advanced imaging biomarkers at kidney failure in patients with ADPKD: a pilot study 

Hypertension  ACC

Prevalence of Chronic Kidney Disease Among US Adults With Hypertension, 1999 to 2018

American journal of hypertension

Efficacy of Allisartan Isoproxil in the Treatment of Mild-to-Moderate Essential Hypertension

Transplantation

Seroprevalence of Measles, Mumps, Rubella, and Varicella-Zoster Virus and Seroresponse to the Vaccinations in Adult Solid Organ Transplant Candidates

American Journal of Transplantation

Qualifying a novel clinical trial endpoint (iBOX) predictive of long-term kidney transplant outcomes

Kidney international report article;

Patient Preferences for the Management of Gastrointestinal Symptoms in Kidney Transplantation: a Discrete Choice Experiment

Implications of Complete Proteinuria Remission at any Time in Focal Segmental Glomerulosclerosis: Sparsentan DUET Trial

The Phenotypic Spectrum of COL4A3 Heterozygotes

High-Throughput Splicing Assays Identify Known and Novel WT1 Exon 9 Variants in Nephrotic Syndrome

JAMA Internal Medicine

Disparities in Kidney Transplant Waitlisting Among Young Patients Without Medical Comorbidities

Hi, This Week in Nephrology, we will be discussing articles published in  October  issues of the Nephrology journals.

 Journal of the American Society of Nephrology

Safety and Preliminary Efficacy of Mesenchymal Stromal Cell (ORBCEL-M) Therapy in Diabetic Kidney Disease: A Randomized Clinical Trial (NEPHSTROM)

Clinical journal of the American Society of Nephrology

Early Risk Stratification for Natural Disease Course in Fabry Patients Using Plasma Globotriaosylsphingosine Levels

Stakeholder Perspectives on Factors Related to Deprescribing Potentially Inappropriate Medications in Older Adults Receiving Dialysis

JAMA

Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection

The ACORN Randomized Clinical Trial

  Nephrology dialysis transplantation  

Comparable outcomes between a combination of peritoneal dialysis with once-weekly haemodialysis and thrice-weekly haemodialysis: a prospective cohort study

The effect of micro-particle curcumin on chronic kidney disease progression: the MPAC-CKD randomized clinical trial

Kidney international  

Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes

American journal of kidney diseases  

Kidney Transplantation From Hepatitis C Virus–Infected Donors to Uninfected Recipients: A Systematic Review for the KDIGO 2022 Hepatitis C Clinical Practice Guideline Update

Acute Declines in Estimated GFR in Blood Pressure Target Trials and Risk of Adverse Outcomes

Clinical kidney journal 

Twenty-four-hour proteinuria levels are associated with adverse pregnancy outcomes among women with CKD 

Critically ill patients with acute kidney injury: clinical determinants and post-mortem histology

Hypertension  ACC

Is Height2.7 Appropriate for Indexation of Left Ventricular Mass in Healthy Adolescents? The Importance of Sex Differences

American journal of hypertension

Observational and Genetic Evidence for Bidirectional Effects Between Red Blood Cell Traits and Diastolic Blood Pressure

Transplantation

Performance and Advancement of the Kidney Solid Organ Response Test

American Journal of Transplantation

Siplizumab combination therapy with belatacept or abatacept broadly inhibits human T cell alloreactivity in vitro

Kidney international report article;

Changes in Kidney Function Among Malaysian Adolescents and Its Determinants

Considerable Variability Among Transplant Nephrologists in Judging Deceased Donor Kidney Offers

Diagnosis of Kidney Diseases of Unknown Etiology Through Biopsy-Genetic Analysis

Black Patients Equally Benefit From Renal Genetics Evaluation but Substantial Barriers in Access Exist

Hi, This Week in Nephrology, we will be discussing article published in  October  issues of the Nephrology journals.

Journal of the American Society of Nephrology

Renin–Angiotensin–Aldosterone System Blockade after AKI with or without Recovery among US Veterans with Diabetic Kidney Disease

Clinical journal of the American Society of Nephrology

Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial

Efficacy and Safety of Upacicalcet in Hemodialysis Patients with Secondary Hyperparathyroidism: A Randomized Placebo-Controlled Trial

Perspectives of Nephrologists on Gender Disparities in Access to Kidney Transplantation

Nephrology dialysis transplantation  

Vitamin K supplementation and bone mineral density in dialysis: results of the double-blind, randomized, placebo-controlled RenaKvit trial 

Peritoneal transformation shortly after kidney transplantation in p

Kidney international  

A cohort study found a high risk of end-stage kidney disease associated with acromegaly

American journal of kidney diseases  

The Impact of the COVID-19 Pandemic on Patients With CKD: Systematic Review of Qualitative Studies

Blood Pressure, Incident Cognitive Impairment, and Severity of CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study

Clinical kidney journal 

Intact FGF23 predicts serum phosphate improvement after combined nicotinamide and phosphate binder treatment in hemodialysis patients

The impact of in-centre haemodialysis treatment on the everyday life of older adults with end-stage kidney disease: a qualitative study

Hypertension  ACC

PREPARE: A Stepped-Wedge Cluster-Randomized Trial to Evaluate Whether Risk Stratification Can Reduce Preterm Deliveries Among Patients With Suspected or Confirmed Preterm Preeclampsia

American journal of hypertension

Specialized Pro-resolving Mediator Improves Vascular Relaxation via Formyl Peptide Receptor-2

Transplantation

Immunized Patients Face Reduced Access to Transplantation in the Eurotransplant Kidney Allocation System

American Journal of Transplantation

Validation of a prediction system for risk of kidney allograft failure in pediatric kidney transplant recipients: An international observational study

Kidney international report article;

Epidemiology and Outcomes of Children with Kidney Failure Receiving Kidney Replacement Therapy in Australia and New Zealand

Feasibility Analysis of Ultrasound-Guided Placement of Tunneled Hemodialysis Catheters

 Rate of Kidney Function Decline is Associated With Kidney and Heart Failure in Individuals With Type 1 Diabetes

Kidney Outcomes Following Utilization of Molecular Adsorbent Recirculating System

Hi, This Week in Nephrology, we will be discussing article published in October issues of the Nephrology journals.

Journal of the American Society of Nephrology

Research and Nonresearch Industry Payments to Nephrologists in the United States between 2014 and 2021

Nephrology dialysis transplantation  

Treatment and long-term outcome in primary nephrogenic diabetes insipidus

Long-term outcomes of COVID-19 survivors with hospital AKI: association with time to recovery from AKI

Kidney international  

American journal of kidney diseases  

Utility of the Kidney Failure Risk Equation and Estimated GFR for Estimating Time to Kidney Failure in Advanced CKD

Multifaceted Quality Improvement Interventions to Prevent Hemodialysis Catheter–Related Bloodstream Infections: A Systematic Review

Clinical kidney journal 

Recurrent cardiovascular events in patients with type 2 diabetes and haemodialysis: analysis from the 4D Study

pted

Hypertension ACC

Unilaterally Selective Adrenal Vein Sampling for Identification of Surgically Curable Primary Aldosteronism

American journal of hypertension

Sex Differences in Atrial Fibrillation and Associated Complications in Hypertensive Patients with Left Ventricular Hypertrophy: The LIFE Study

Transplantation

Evaluation of Immunocompetence and Biomarkers of Tolerance in Chimeric and Immunosuppression-free Kidney Allograft Recipients

American Journal of Transplantation

Survival after kidney transplantation compared with ongoing dialysis for people over 70 years of age: A matched-pair analysis

Kidney international report :

Effect of a Multifaceted Intervention on the Incidence of Hemodialysis Catheter Dysfunction in a National Stepped-Wedge Cluster Randomized Trial

Residual Kidney Function and Cause-Specific Mortality Among Incident Hemodialysis Patients

Determinants of Kidney Failure in Primary Hyperoxaluria Type 1: Findings of the European Hyperoxaluria Consortium

Changing Phenotypes and Clinical Outcomes Over Time in Microscopic Polyangiitis

Hi, This Week in Nephrology, we will be discussing article published in September issues of the Nephrology journals.

Journal of the American Society of Nephrology

Dysfunctional Coupling of Cerebral Blood Flow and Susceptibility Value in the Bilateral Hippocampus is Associated with Cognitive Decline in Nondialysis Patients with CKD

Efficacy and Safety of Eculizumab in Pediatric Patients Affected by Shiga Toxin–Related Hemolytic and Uremic Syndrome: A Randomized, Placebo-Controlled Trial

Clinical journal of the American Society of Nephrology

Long-Term, Real-World Kidney Outcomes with SGLT2i versus DPP4i in Type 2 Diabetes without Cardiovascular or Kidney Disease

Immunosuppression versus Supportive Care on Kidney Outcomes in IgA Nephropathy in the Real-World Setting

Nephrology dialysis transplantation  

Malignancy risk in kidney transplant recipients exposed to immunosuppression pre-transplant for the treatment of glomerulonephritis Acute kidney injury in bortezomib-treated patients with multiple myeloma

Kidney international  

A nationwide cohort study comparing the effectiveness of diuretics and calcium channel blockers on top of renin-angiotensin system inhibitors on chronic kidney disease progression and mortality

American journal of kidney diseases  

Integrated Analysis of Blood and Urine Biomarkers to Identify Acute Kidney Injury Subphenotypes and Associations With Long-term Outcomes

Evaluation of Plasma Biomarkers to Predict Major Adverse Kidney Events in Hospitalized Patients With COVID-19

 Clinical kidney journal 

Kidney injury molecule 1 (KIM-1): a potential biomarker of acute kidney injury and tubulointerstitial injury in patients with ANCA-glomerulonephritis

Clinical and immunological characteristics of patients with combined anti-glomerular basement membrane disease and IgA nephropathy

Hypertension  ACC

Association Between Maternal Glucose Levels in Gestational Diabetes Screening and Subsequent Hypertension

 American journal of hypertension

SNAP Participation and Medication Adherence Among Older Black Medicaid-Insured Individuals Living With Hypertension

Transplantation

Cost-effectiveness of Kidney Transplantation From Donors at Increased Risk of Blood-borne Virus Infection Transmission

Outcomes With Belatacept Exposure During Pregnancy in Kidney Transplant Recipients: A Case Series

American Journal of Transplantation

Diagnosis and treatment of allograft rejection in islet transplantation

Kidney international report  

Effect of Belimumab on Preventing de novo Renal Lupus Flares

The Association Between Metabolic Syndrome, Hyperfiltration, and Long-Term GFR Decline in the General Population

 Hyperfiltration can prevent loss of GFR in persons with MetS.

Hi, This Week in Nephrology, we will be discussing article published in September issues of the Nephrology journals.

Journal of the American Society of Nephrology

Genome-Wide Association Study of CKD Progression

Effects of a More Selective Arteriovenous Fistula Strategy on Vascular Access Outcomes

Clinical journal of the American Society of Nephrology

Ferric Carboxymaltose in Iron-Deficient Patients with Hospitalized Heart Failure and Reduced Kidney Function

Discrepancies between Cystatin C–Based and Creatinine-Based eGFR

Nephrology dialysis transplantation  

Long-term peridialytic blood pressure changes are related to mortality

Early acute kidney injury is associated with in-hospital adverse outcomes in critically ill burn patients: an observational study

Kidney international  

Bio-impedance spectroscopy added to a fluid management protocol does not improve preservation of residual kidney function in incident hemodialysis patients in a randomized controlled trial

American journal of kidney diseases  

Serum Potassium and Risk of Death or Kidney Replacement Therapy in Older People With CKD Stages 4-5: Eight-Year Follow-up

Metformin Use and Long-term Clinical Outcomes in Kidney Transplant Recipients

Clinical kidney journal 

Associations between eGFR and albuminuria with right ventricular measures: the MESA-Right Ventricle study 

Standard versus no post-filter ionized calcium monitoring in regional citrate anticoagulation for continuous renal replacement therapy (NPC trial)

Hypertension  ACC

Intensive Blood Pressure Lowering Improves Left Ventricular Hypertrophy in Older Patients with Hypertension: The STEP Trial

American journal of hypertension

Intensive Blood Pressure Control and Cardiovascular Outcomes in Elderly Patients: A Secondary Analysis of SPRINT Study Based on a 60-Year Age Cutoff

Transplantation

Robotic Versus Laparoscopic Donor Nephrectomy: A Retrospective Bicentric Comparison of Learning Curves and Surgical Outcomes From 2 High-volume European Centers

Bariatric Surgery in Severely Obese Kidney Donors Before Kidney Transplantation: A Retrospective Study

American Journal of Transplantation

The role of interleukin-21 in COVID-19 vaccine–induced B cell–mediated immune responses in patients with kidney disease and kidney transplant recipients

Kidney international report

Randomized Controlled Clinical Trial of the Effect of Treatment with Vitamin K2 on Vascular Calcification in Hemodialysis Patients (Trevasc-HDK)

;Infectious Risk and Variability of Hemoglobin Level in Patients Undergoing Hemodialysis

Articles:

Journal of the American Society of Nephrology: Efficacy and Safety of Eculizumab in Pediatric Patients Affected by Shiga Toxin–Related Hemolytic and Uremic Syndrome: A Randomized, Placebo-Controlled Trial

Clinical journal of the American Society of Nephrology: Ferric Carboxymaltose in Iron-Deficient Patients with Hospitalized Heart Failure and Reduced Kidney Function

Nephrology dialysis transplantation: Malignancy risk in kidney transplant recipients exposed to immunosuppression pre-transplant for the treatment of glomerulonephritis

Kidney International:Bio-impedance spectroscopy added to a fluid management protocol does not improve preservation of residual kidney function in incident hemodialysis patients in a randomized controlled trial .

American journal of kidney diseases  Serum Potassium and Risk of Death or Kidney Replacement Therapy in Older People With CKD Stages 4-5: Eight-Year Follow-up

Clinical kidney journal Women's representation in clinical trials of patients with chronic kidney disease

Hypertension  ACC: Intensive Blood Pressure Lowering Improves Left Ventricular Hypertrophy in Older Patients with Hypertension: The STEP Trial

American journal of hypertension effects of allisartan isoproxil monotherapy on blood pressure (BP)