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TIAFT Bulletin preview - Issue 54(2)
30 Aug 2024
00:12:37
We'll be previewing issues of the TIAFT Bulletin as they are released every few months.
Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here. Geraldine's new podcast is called The Analytical Zen Podcast (buzzsprout.com), give it a go! Contact us at toxpod@tiaft.org
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released every few months.
Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
Artificial Intelligence is quickly becoming one of the key tools in all fields of science. In this episode we look at how it's being used in forensic toxicology, and how it might be used in the future.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
Did you know that TIAFT presidents have a synergistic effect? Recorded live at the TIAFT 60th Jubilee in London, this panel discussion hosted by Nikolas Lemos features a bunch of former TIAFT presidents giving their perspectives on a wide range of issues facing forensic toxicologists. Thanks to all for participating, and here's to the next 60 years!
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss an increasing trend of xylazine in fentanyl supplies, the recent scheduling of some NPS by the United Nations, and the emergence of semi-synthetic cannabinoids including HHC.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.
Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
5 in 30 (Mushrooms, chemical warfare, and machine learning)
07 Mar 2023
00:41:01
We look at 5 recent publications in the field of toxicology.
Palm, E. et al. Machine learning for absolute quantification of unidentified compounds in non-targeted LC/HRMS. (2022) Molecules, https://doi.org/10.3390/molecules27031013.
Bishop-Freeman, S. et al. Melatonin supplementation in undetermined pediatric deaths. (2022) Journal of Analytical Toxicology, https://doi.org/10.1093/jat/bkac033.
Flament, E. et al. Determination of orellanine in human biological matrices using liquid chromatograph with high-resolution mass spectrometry detection: A validated method applied to suspected poisoning cases. (2023) Journal of Analytical Toxicology, https://doi.org/10.1093/jat/bkac018
Wang, Y. et al. Operation of the anti-doping laboratory for the Beijing 2022 Olympic and Paralympic Winter Games. (2022) Drug Testing and Analysis, DOI: 10.1002/dta.3384.
Otsuka, M. et al. Analysis of degradation products of Novichok agents in human urine by hydrophilic interaction liquid chromatography-tandem mass spectrometry. (2022) Forensic Toxicology, https://doi.org/10.1007/s11419-022-00656-4.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
Tim is joined by Samantha Tolliver, Chief Toxicologist in the District of Columbia, to discuss the challenges of running a modern forensic toxicology laboratory.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.
Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss the recently released UNODC report on Current NPS Threats, as well as benzodiazepine trends and the importance of Drug Checking programs.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
At the TIAFT2022 conference in Versailles, Peter caught up with a few fellow toxicologists: Michael Scholz (Switzerland), Brigitte Desharnais (Canada), Svante Vikingsson (USA), and Jean-Claude Alvarez (France).
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
TIAFT meetings are back! Peter is joined on stage in Versailles by Sarah Wille (Belgium), Rebecca Hartman (USA) and Jennifer Schumann (Australia) to discuss what's hot and what's not in the field of toxicology.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
5 in 30 (Semi-liquid membranes, Kamini balls and mythical creatures)
28 Aug 2022
00:33:48
We look at 5 recent publications in the field of toxicology.
Huen-Yin Tang M, et al. Ropinirole metabolite mimics a new psychoactive substance (4-HO-MET) in LC-MS/MS. (2022) Forensic Science International, https://doi.org/10.1016/j.forsciint.2021.111151.
Shang, Q. et al. Multi-extraction system with identical supported semi-liquid membrane: Enhanced stability for coextraction of acidic and basic drugs. (2022) Talanta, https://doi.org/10.1016/j.talanta.2022.123485.
Khan, T. Kamini, a little recognised source of illicit opioid: A case series of 12 patients. (2022) Drug and Alcohol Review, DOI: 10.1111/dar.13475.
Trigg, S. The alprazolam analogue 4’-chloro deschloroalprazolam identified in seized capsules. (2022) Drug Testing and Analysis, DOI: 10.1002/dta.3325.
Brooks-Lim, E. Fatal ingestion of Taxus baccata: English yew. (2022) Journal of Forensic Sciences, DOI: 10.1111/1556-4029.14941.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.
Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
Green Analytical Toxicology with Jose Luiz da Costa
03 May 2022
00:36:10
Tim chats with Jose Luiz da Costa, Professor of Toxicology at the University of Campinas in Brazil, about his work with NPS and advancements in 'Green Analytical Toxicology'.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We continue with another episode recorded live at FACTA2022 in Brisbane, Australia.
It's a panel discussion on medicinal cannabis featuring Associate Professor Vicki Kotsirilos, Professor Olaf Drummer, Professor Thomas Kraemer, and Dr Samuel Banister.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
Old Approaches to Fresh Problems (live at FACTA2022)
13 Apr 2022
00:25:34
We finally attend a real life conference again, and turn the conference theme, "Fresh approaches to old problems" , on its head! Recorded live at FACTA2022 in Brisbane, Australia.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released every few months.
Special thanks to Jennifer Schumann and Rebecca Hartman, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss cathinones, the recent contamination of synthetic cannabinoids with brodifacoum, and the future of psychedelics.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.
Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We were at the TIAFT Virtual Conference in February! This episode is audio from a couple of sessions we did there - busting some more myths in forensic toxicology.
Plus we had our first ever competition! Stay tuned til the end to find out who won the prestigious Toxpod mug...
A couple of examples of recommendations for first responders who may encounter opioids from the USA and the UK.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.
Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We tell the story of the TIAFT2020 conference in Capetown, South Africa - a conference that never actually happened.
Thanks to Alicia Evans, Bronwen Davies, Lorna Martin, Marc LeBeau, Simon Elliott, Dimitri Gerostamoulos and Michaela Kenneally for taking part in this episode.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.
Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
These updates will be a regular part of our podcast schedule, letting you know about recent developments in NPS markets, detection and harms. In this episode we discuss Early Warning Systems and potential changes in the synthetic cannabinoid market.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We'll be previewing issues of the TIAFT Bulletin as they are released each quarter.
Special thanks to Jennifer Schumann and Sarah Wille, editors of the TIAFT Bulletin. For more information on the Bulletin, including how to submit content, click here.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
5 in 30 (Chemometrics, single hair analysis and GC-VUV)
22 Jun 2021
00:36:01
We look at 5 recent publications in the field of toxicology.
Polettini A, et al. LC–QTOF-MS Presumptive Identification of Synthetic Cannabinoids without Reference Chromatographic Retention/Mass Spectral Information. II. Evaluation of a Computational Approach for Predicting and Identifying Unknown High-Resolution Product Ion Mass Spectra. (2021) Journal of Analytical Toxicology, 45(5):440-61.
Kuwayama, K. et al. Development of the “selective concentration” analytical method for drug-containing hair regions based on micro-segmental analysis to identify a trace amount of drug in hair: hair analysis following single-dose ingestion of midazolam. (2021) Forensic Toxicology, 39(1):156-66.
Robin, T. First-Line Toxicological Screening with Fully Automated Extraction. (2021) Journal of Analytical Toxicology, 45(3):252-68.
Kranenburg, R. Spotting isomer mixtures in forensic illicit drug casework with GC–VUV using automated coelution detection and spectral deconvolution. (2021) Journal of Chromatography B, 1173:122675.
Elmsjö, A. Post-Mortem Metabolomics: A Novel Approach in Clinical Biomarker Discovery and a Potential Tool in Death Investigations. (2021) Chemical Research in Toxicology, 34(6):1496-1502.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
We chat with Alex Krotulski about his work with CFSRE and NPS Discovery. You can find out more about these initiatives, and access the many resources they produce, at https://www.npsdiscovery.org/
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
Tim chats with Marthe Vandeputte about the current and potential uses of activity based assays in forensic toxicology. Links to a couple of Marthe's papers on the topic are below:
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
5 in 30 (Impairment apps, zebrafish and Scottish prisons)
18 May 2021
00:37:33
We look at 5 recent publications in the field of toxicology.
Karoly, H. et al. Effects of high-potency cannabis on psychomotor performance in frequent cannabis users. (2020) Cannabis and Cannabinoid Research, X:X, 1-9
Prado, E. et al. Metabolism of synthetic cathinones through the zebrafish water tank model: a promising tool for forensic toxicology laboratories. (2021) Forensic Toxicology, 39: 73-88
Chu, M. et al. Time-dependent changes in THC concentrations in deceased persons. (2021) Journal of Analytical Toxicology, 45:1-7
Van Schalkwyk, F. et al. Fatal pyrrolizidine alkaloid poisoning of infants caused by adulterated Senecio coronatus. (2021) Forensic Science International, 320:110680
Norman, C. et al. Large-scale evaluation of ion mobility spectrometry for the rapid detection of synthetic cannabinoid receptor agonists in infused papers in prisons. (2021) Drug Testing and Analysis, 13:644–663
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
How confident are you that your analytical methods won't miss a target analyte? In the first episode of season 4, we discuss the potential for false negative results in forensic toxicology.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
5 in 30 (Fingerprints, SWATH and retrospective screening)
16 Jun 2020
00:38:55
We look at 5 recent publications in the field of toxicology.
Costa, C. et al. Distinguishing between contact and administration of heroin from a single fingerprint using high resolution mass spectrometry. (2020) Journal of Analytical Toxicology. 44: 218-225
Kaufmann, A. et al. Partially overlapping sequential window acquisition of all theoretical mass spectra: A methodology to improve the spectra quality of veterinary drugs present at low concentrations in highly complex biological matrices. (2020) Rapid Communications in Mass Spectrometry. 34: e8638
Kraemer, M. et al. Detectability of various cannabinoids in plasma samples of cannabis users: Indicators of recent cannabis use? (2019) Drug Testing and Analysis. 11:1498-1506
Margalho, C. et al. Determination of new psychoactive substances in whole blood using microwave fast derivatization and gas chromatography/mass spectrometry. (2020) Journal of Analytical Toxicology. 44:92-102
Gundersen, P. et al. Retrospective screening of synthetic cannabinoids, synthetic opioids and designer benzodiazepines in data files from forensic post mortem samples analysed by UHPLC-QTOF-MS from 2014 to 2018. (2020) Forensic Science International. 311: 1-11
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
"I used to keep a quadrupole in my pocket..." Who else can say that? Bryan received the The International Association of Forensic Toxicologists' Alan Curry Award in 2018 and was present at the "revolt" of 1963 that led to TIAFT's genesis. Even after 6 decades in toxicology he continues to support the development of our science and our scientists through the Bryan Finkle Visiting Scientists Grant. A true giant of our field. Come along for the ride! Contact us at toxpod@tiaft.org
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The California Association of Toxicologists Spring meeting has been postponed due to COVID restrictions, but that won't stop us from chatting with some of the planned speakers!
Thanks to Luke Rodda, Jarrad Wagner, Juliet Kinyua and Alan Wu for participating in this episode.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.
5 in 30 (Isotonitazene, wastewater and MS interferences)
28 Apr 2020
00:38:47
We look at 5 recent publications in the field of toxicology.
Blanckaert, P. et al. Report on a novel emerging class of highly potent benzimidazole NPS opioids: Chemical and in vitro functional characterization of isotonitazene. (2020) Drug Testing and Analysis. 12: 422-430
Reinstadler, V. et al. A validated workflow for drug detection in oral fluid by non-targeted liquid chromatography-tandem mass spectrometry. (2019) Analytical and Bioanalytical Chemistry. 411:867-876
Benaglia, L. et al. Testing wastewater from a music festival in Switzerland to assess illicit drug use. (2020) Forensic Science International. 309:1-8
Munoz-Munoz, A. et al. Characterization of an Amphetamine Interference from Gabapentin in an LC–HRMS Method. (2020) Journal of Analytical Toxicology. 44:36-40
Darke, S. et al. Characteristics and circumstances of death related to gamma hydroxybutyrate (GHB). (2020) Clinical Toxicology. Published online 18 Feb 2020.
The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.