In this episode, Evan discusses his departure to Canada and Tom gives an Irish quiz in tribute St Patrick's Day. In science this month, the lads discuss Neuralink's recent implant in a patient, as well as the recent restrictions on puberty blockers in the UK. In his main story, Tom discusses the scientific necessity behind using animals in research and whether they are useful as disease models to study drugs. So join us for an episode of education, discussion and fun!

We are delighted to welcome Dr Patrick Doohan on our latest episode. Patrick is a mathematical modeller at the Jameel Institute, based in the Department of Infectious Disease Epidemiology at Imperial College London. We discuss Pandemic Preparedness, Priority Viral Pathogens as assigned by the WHO, Epidemiological-Economic models, Model Scenarios including the COVID-19 pandemic and what his thoughts are on global readiness for future pandemics. Join us for some interesting discussion about pandemic preparedness.

On the 50th episode of the podcast, hosts Tom and Evan have a lively discussion about male erogenous zones before diving into some intriguing science news. Tom shares the latest research on male contraceptives, while also taking a moment to celebrate International Women in Science Day by highlighting some lesser-known female scientists from history. Meanwhile, Evan explores the insights into the second phase of the COVID origins study conducted by the WHO.

The main story is divided into two parts, both focused on sperm donation and ethics. In the first part, Evan examines the discontinuation of time limits for using donated sperm and delves into the scientific, ethical, and moral implications of this change. In the second part, he discusses posthumous sperm retrieval and the associated ethical questions.

Join us for this special episode as we reflect on our 50 episodes with a mix of humor, science and discussion.

New year, new episode! The lads assess their goals for the new year including eating less meat and getting fit. Evan examines the science stories to look forward to in 2023, including cancer vaccine trials, further space imaging technology, returning to the moon and Alzheimer's drug development. Tom discusses the new field of meat cultivation, aka “lab grown meat” and gives a background on what it is, how it works, its suitability for vegetarians and vegans and the implications for traditional farming. So join us for some laughs, discussion and education on all things science.

Welcome to the final episode of The Sceptically Inclined Science Podcast for the year! On todays episode we give a run down of our favorite science stories from the past 12 months. In the spirit of Christmas, the guys discuss Santa's characteristic face features and AI. In their 2022 review, Tom and Evan discuss topics such as the launch of the James Webb Telescope, the "beauty premium" in college grading systems, animal to human organ transplants, the tough placebo role in Shigella vaccines and how microdosing may not be as effective as some people believe. So join us for one final episode, for a laugh, some discussion and reflection on what 2022 meant for science.

Today, Tom humble brags about his recent 7.5 km run in Netherlands while Evan poses the question 'Is lead poisoning the reason behind the Roman empire's success?'. In the news headlines, the lads discuss psilocybin use in treatment-resistant depression, the reasons for octopuses' tendencies to throw objects at each other and the declining sperm counts in men. In his main story, Tom speaks about dyslexia and his personal experiences. The lads discuss possible causes of dyslexia and explore the multifactorial nature of learning disabilities. So join us for some discussion, humour and insights into the world of science.

Today, the lads are humbled by their inability to predict the Nobel Prize winners and things get heated when Tom discusses a new paper on the origins of Covid-19. In his main story, Evan focuses on the long term effects of Covid-19 and the desperate measures patients are going through to try to obtain treatment. including anticoagulant therapy and apheresis. The lads investigate the so called benefits and risks of such treatment and whether trials play a role or end up delaying treatment options for desperate patients. So join us for some craic, discussion and education.

Welcome back for Season 3 of The Sceptically Inclined Science Podcast. On today's premiere, the guys discuss their summer holidays while Evan examines the big science stories of the summer including pictures from the James Webb Telescope, CRISPR trials beginning in humans and whether even unborn babies like the taste of kale. Tom discusses an exciting new paper showing that stem cells, rather than a sperm and egg, could be used for embryo development. They also speculate on potential winners of the Science Nobel Prizes. So join us for discussion, fun and some education!

Join Evan and Tom as they take a trip down memory lane and unwrap the stories and interviews of season 2. They put each other to the test to see how well they know each other after two seasons. They also examine the weird science stories released so far this year with Tom investigating Tourette's syndrome cases flaring up among teens on social media while Evan discusses the link between outdoor cat ownership and psychosis in males. So join us for this season finale for fun, discussion and some laughs.

On today's special episode, Tom flies in for a in-person discussion with Evan. They talk about the flaws of Spotify while Tom casts his sceptical eye on a new drug that has put all trial participants of rectal adenocarcinoma into remission. In his main story, Evan examines the current state of gene therapy, looks at a current gene therapeutic for Sickle Cell disease and the disadvantages of the therapy. So join us for discussion, craic and some education.

On today's episode the lads are having a hot science summer with Tom discussing his moderation at a recent discrimination in science event while Evan talks about a publicly available AI image generator. In science news headlines, Evan examines the high rates of people still suffering from long COVID-19, the current monkeypox situation, and Tom dives into the flawed world of Nutrition Science.

Today, Evan and Tom have the pleasure to speak with Dr Anthony Kaveh MD, keynote speaker and founder of Medical Secrets.

Anthony is a California-based anaesthesiologist and integrative medicine specialist. We picked Anthony's brain about the science of anaesthesia, what happens when things go wrong, and what exactly is an integrative medicine specialist? It did not take long for us to dive into the topic of psychedelic therapies and the effect of recreational drugs on the human body during anaesthesia. Anthony has developed a large social media presence thanks to his medical and educational videos and posts across a multitude of channels. Simply search for Medical Secrets, or find links to his channels below:

www.MedicalSecretsMD.com YouTube: https://www.youtube.com/medicalsecrets TikTok: https://www.tiktok.com/@medicalsecrets Facebook: https://www.facebook.com/medicalsecretsMD Instagram: https://www.instagram.com/medicalsecretsmd/

Join Evan and Tom as they discuss a new study that investigates the deaths associated with hydroxychloroquine during the pandemic. Can Tom distinguish the sounds of frustrated vs happy chickens? Hear about recent clinical trials on groundbreaking drugs such as mRNA treatment for cholesterol reduction and Vitamin A derivatives that can halt eye degeneration in Stargardt disease. They also attempt to uncover the mysteries of ancient DNA that has been shown to reveal the origins of Multiple Sclerosis in Europe.

On this week's episode the lads recall their trip to New York while Tom gives his thoughts on a recent sexual harassment ruling for a bald man. 

In their science stories, Tom discusses the infamous "doorway" on Mars and the use of lunar soil to grow plants. Evan examines the phenomenon of Fertility Fraud, the topic of a new Netflix documentary, where women were inseminated with the sperm of their fertility doctor, without their consent.

On today's episode we are joined by Professor Michael Levin from Tufts University, Massachusetts. Michael completed his PhD at Harvard University in the field of Genetics, where he characterised the molecular genetic mechanisms of embryologic left-right asymmetry. His PhD research was recognised by the journal Nature as a “Milestone in Developmental Biology in the last century”. Currently he is the primary investigator and director at Allen Discovery Centre at Tufts University and Director at Tufts Centre for Regenerative and Developmental Biology.

We talk to Michael about Bioelectricity vs Genetics, the Technological Approach to Mind Everywhere (TAME), Limb Regeneration and Xenobots. So join us for a very interesting and informative discussion!

In this episode, Evan reveals how scientists actually flex on each other and Tom shares how an experience being blind truly opened his eyes. Evan re-examines the new Alzheimer's drug after trial data was finally released while Tom investigates the story of how gaps from the original human genome project have only been filled in now. Here, you can learn more about a charity walk at the 'de4daagse' and have the opportunity to support Tom and his team. Listen to the episode to learn more: https://bit.ly/3jZXs4i

In this episode Tom reveals his recent weight scare and talks about aphasia, a condition with recent relevance after Bruce Willis' diagnosis. Evan investigates the Opioid crisis and the unknown role Johnson & Johnson played in its propagation.

Join the guys on a very special episode featuring Professor Carel le Roux. Carel is a physician working in St. Vincent’s Hospital in Dublin, he is also a Professor of experimental pathology at University College Dublin. His work and research are focused on the physiological role and pathological changes in appetite control, the impact of bariatric surgery on diabetes and concerns with increased mortality and morbidity associated with obesity and diabetes.

During the conversation we discuss the future of bariatric surgeries, research into appetite control via hormone therapy and general health concerns around obesity, asking the question if obesity should be considered an addiction or disease?

Our interview with Carel couldn’t be timed better as this week European Medical Agency approved the drug Semaglutide, also known as Wegovy. Wegovy is a hormone-based medication promoting long-term weight management.

If you would like to learn more about Professor Carel and his work, follow him on Twitter @carel_leroux, learn more about the disease of obesity at https://www.itsnotyourfault.ie/ and to hear more about Wegovy visit https://www.wegovy.com/

Thanks for listening!

In this episode Tom brags about his new tattoo and a habit of journaling. Evan brings us back to 2019 and tries to make sense of the origins of the COVID-19 pandemic while Tom explores the secrets of limb regeneration via a new paper which explores an animal model in which limb regeneration was achieved with promising results.

In Episode 34 of the podcast, Tom discusses his aspirations to own a tooth necklace while the lads lament their nations' poor performance at the Winter Olympics. In his main story, Tom sets the story straight on the new HIV variant while Evan examines ketamine for acute suicidal ideation along with microdosing in anxiety treatment and what this could mean in the future of mental health treatment.

On today's episode the guys discuss the new marketing methods of crypto.com, Tom examines a new early diagnostic test for lung cancer while Evan dives into the recent row between the British Medical Journal and Facebook who labelled one of their articles as misinformation, and what this could mean for the future of science articles on the site.

Welcome to the first episode of 2022 where the lads have a quick recap of science over the festive period, including sex in the pandemic era and the 'Shkreli' awards. In his main story, Tom questions the claims of higher rates of myocarditis in vaccinated people versus individuals infected with SARS-CoV-2.

Join us for our final episode of 2021 where Tom and Evan review the science of the past year. We remember the most exciting news stories, including mRNA breakthroughs and some of the weird and funny headlines, like, 'What animal would live in a communist society?'. We also make some predictions for science in 2022. So top your year off with some humour, discussion and education on The Sceptically Inclined Podcast!

Join us for a whirlwind recap of 2023 in science. We'll cover the Alzheimer's drug breakthrough, mRNA vaccines for RSV, and COVID-19's global health status shift. Dive into Mars exploration hurdles, Barbie's educational evolution, spider venom as a Viagra alternative, psychedelics for PTSD and depression in Australia, and the quirkiest Ig Nobel Prize winners. Stay tuned a scientific rollercoaster!

On today's episode, the lads debate a new pilot study being introduced by the UK government to sequence the genome of children at birth with Tom being pro while Evan takes an opposing position. Tom gives his thoughts on his recent Dan Brown book experience while Evan examines a new landmark case of "wrongful conception". So join us for some laughs, discussion and debate on the Sceptically Inclined Science Podcast

In today's episode, Evan reassures Tom that lockdowns are still a good preventive measure against COVID-19 and sums up COP26 as an unfortunate failure. On a positive note, the booster vaccine against COVID-19 shows very promising results. Tom compares solid tissue biopsies and liquid biopsies - is one better than the other? Can we get rid of one? Tune in to find out!

In this weeks episode we learn that not only does James Bond have amazing espionage skills but also an impenetrable immune system. 

  Tom celebrates the Phase II//III results for antiviral drug "Paxlovid" against SARS-COV-2 and dives into the events at COP26 while Evan evaluates the controversial approval of a new Alzheimer's drug, Aducanumab, and examines what the clinical trial results actually said.

On today's episode we are joined by special guest Professor Han Brunner. Prof Brunner has worked on understanding the MAOA gene mutation, and how it leads to abnormal, unpredictable behaviour as well as uncontrolled violence. Learn about the science behind MAOA influence on brain development, the influence of maltreatment on behaviour and how MAOA status has influenced court cases previously in an exciting and insightful discussion.

In this episode, Evan reviews the Nobel Prize winners in the scientific categories and the other science news including the malaria vaccine and a new sickle cell anemia treatment. In his main story, Tom discusses the X and Y chromosomes, X-inactivation and treatment options for chromosome inactivation.

Join Evan and Tom as they welcome you back to a new season of The Sceptically Inclined Science Podcast. In this episode, the guys talk scientific YouTube comments, Tom covers interesting science headlines that you might have missed over the summer and Evan examines booster vaccines, waning immunity and full authorisation of the Pfizer-BioNTech Covid-19 vaccine. So join us for a new season of laughs, discussion and fun accessible science chat!

Join the guys for the final episode of the season! Tom, Evan and John reflect on a whole year of non-stop podcasting. Along with nominating their favourite moments and guests, the guys discuss stories that didn't make the cut. From animals that Tom thinks he could manhandle, to Evan's crazy sleep-talking. So take a trip down memory lane with the lads as they conclude this season on a high and explicit note!

On this episode we are joined by Professor Ivan Perry. Professor Perry is the Dean of the School of Public Health at University College Cork with particular expertise in cardiovascular disease, diabetes and self-harm. We discuss obesity in Ireland, his thoughts on the public health response to the Covid-19 pandemic in Ireland and the effect it has had on mental health. Enjoy!

Join the guys for a special episode featuring Dr Alex Garanto. Alex is an Assistant Professor at Departments of Pediatrics and Human Genetics in Radboud University Medical Center. Alex has over a decade of experience working on oligonucleotides based therapies for inherited retinal diseases. Tom and Evan discuss with Alex the complexity of eye, the burden of inherited blindness on patients and the role of pharmaceutical companies in developing gene therapies. The guys also had the opportunity to discuss the importance of negative results and advantages of open access journals among other topics. So join us for some great discussion and insights!

Welcome to episode 21 where the lads discuss what it means to be a science influencer and using PubMed to feel better about themselves. in their main stories, Tom examines how some genetic diseases can evolve to provide an advantage in infectious diseases while Evan dives into COVID-19 vaccination in children and the difficulties in its implementation. All topped off with some discussion, humour and science news.

Join Evan and Tom as they dive into the rising infant mortality rate in the US and the groundbreaking approval of the first CRISPR treatment for Sickle Cell and Thalassemia in the UK. They explore the nuances of preventative medicine and discuss fact-based policies versus alternative practices for preventative medicine promotion. Tune in for some discussion, education and fun!

In Episode 20, Tom discusses his disappointment with Assassins Creed and Evan ponders his new haircut choice. For the news headlines John discusses Neuralink's monkey brain pong, Tom examines the updated CDC mask guidelines and Evan investigates smell training. In the main news, Tom discusses his experience with pain and a new study that may help reduce this while Evan examines the pros and cons of a vaccine passport. So join us for some humour, discussion and science fun.

Welcome to Episode 19 where we talk blood personalities, blood clots and vaccines. The guys try to decipher John's blood group based on his personality while in the headlines Evan discusses new findings in relation to Neanderthals. In their main stories, Evan has a deep dive into the recent troubles with the Oxford/AstraZeneca vaccine and Tom examines the potential of RNA technology in treating Multiple Sclerosis. So join us for humour, discussion and more.

On this episode Evan and Tom talk coronavirus, concussion and blood products of the future. Tom reveals his awkward encounter while getting some sausage and talks about synthetic cells. Evan briefly examines the AstraZeneca vaccine and the the new WHO report on the origin of COVID-19. In their main stories Evan discusses a new diagnostic test for concussion while Tom wraps up his series on blood substitutes and potential future opportunities. All topped off with some discussion and humour.

Join the guys for a very special episode featuring Professor Luke O'Neill. Luke is an immunologist, biochemist and author based in Trinity College Dublin. Tom and Evan discuss the work Luke is doing in his lab to combat COVID-19, his thoughts on the European pause of the AstraZeneca vaccine and the challenges of science communication in an era of misinformation. So join us for some great discussion and insights from one of Ireland's top research professors.

Join the guys as Evan discusses getting his first vaccine dose and his urge to buy Microsoft products, Tom's hope to start LSD micro-dosing takes a step forward and John rejoins to relive the perseverance rover landing on Mars. For their main stories, Evan casts a sceptical eye on the hype of the microbiome while Tom gives us part one of his talk on blood transfusion and the possibility of using non-blood based products. All topped off with some discussion, humor and debate.

Join us on Episode 15 where are joined by animal cognition researcher Dr Jim McGetrick. Jim is a Postdoctoral scientist, specialising in animal behaviour and higher cognition, primarily in dogs. The guys quiz Jim on all things animal related ranging from whether your dog can truly love you, to monogamy in birds and what your dog breed can really say about you. All topped off with some humour, discussion and hopefully you can leave with some cool facts about animal behavioural science. 

On Episode 14 of the Sceptically Inclined Science Podcast the guys discuss an unorthodox method of swabbing for Covid-19 and they try out a new segment where they discuss David Attenborough, the "nature guy". For their main stories, Evan examines deep brain stimulation and how it is used in treating disease, along with Neuralink, while Tom discusses the male "pill", its use as a contraceptive and everyone's reaction to taking it. All topped off with some humour, discussion and fun.

On Episode 13 of the Sceptically Inclined Science Podcast, the lads discuss Netherlands under curfew, moving away from WhatsApp and Michelle Obama becoming a Jedi. In the main discussion, Tom investigates a new peptide that may help in the treatment of COVID-19 while Evan examines asymptomatic transmission and whether it is a driver of cases or not. So join us for some discussion, laughs and news from the science world.

On Episode 12 of the Sceptically Inclined Science Podcast the guys welcome you to the new year by talking about all things vaccine-related. Tom discusses recent anaphylactic reactions in some vaccine recipients and the molecular mechanisms of how the Pfizer/BioNTech and Moderna vaccines work.

Evan examines vaccine trials, how they were carried out for the vaccines developed for SARS-COV-2 and casts his sceptical eye on the recent Pfizer/BioNTech data that had been released.

Join Sceptically Inclined Science for the last episode before Christmas break. The guys discuss their headlines: a new animal model for Covid-19 and targeting the subconscious in reducing post-operative pain.

In their main stories Evan investigates a Danish study of face masks and the politicisation of science in a Covid-19 era while Tom discusses mitochondrial diseases and the 'three parent baby'. 

All topped off with discussion, humour and some reflection on the year.

Join us for our much-anticipated return episode where we recap summer adventures, Nobel Prize winners, a speech recovery brain interface, and a cannabis meta-analysis. Join us for insights into science's latest discoveries and hot-button issues on the Sceptically Inclined Science Podcast!

Join the lads as they reflect on an important milestone, 10 episodes of Sceptically Inclined! As well as celebrating this milestone, the guys discuss the link between moths and stealth missions and the potential for a new Jurassic World movie to be set in Ireland.

In their main stories, Tom delves into nanomedicine and its potential for treating human disease while Evan discusses the new Oxford/AstraZeneca vaccine and the implications of their new announcements.

So join us for episode 10 with humour, discussion and much more.

On Episode 9 of the podcast, Tom tests Evan's knowledge of all things Polish after the country celebrates its Independence Day. In news headlines, the guys discuss mice on DMT, HIV prophylaxis drugs and how mink are altering the SARS-COV-2 genotype.

Tom discusses the possibilities of growing teeth in a lab and Evan does a deep dive into the new Pfizer vaccine and examines what they are claiming but, more importantly, what they are not... yet.

All topped off with some humour, discussion and now John as a regular guest.

On today's episode the guys get into the Halloween spirit by discussing their favourite weird and unusual science stories - the dancing plague and the disorder known as prosopagnosia.

Tom examines a new method to get mice swole and how it could help astronauts in space while Evan can't hide his smugness when his skepticism of Remdesivir proves to be correct.

All topped off with some news headlines, discussion, humour and space expert John.

On today's episode, Sceptically Inclined is joined by special guest Marc Abrahams, founder of the Ig Nobel Prize and editor of the Annals of Improbable Research.

The guys find out the concept behind the Ig Nobel Prizes, the process of becoming a winner and how it is seen within the science community. Marc discusses this years ceremony and the logistics of organising a ceremony during a pandemic. Evan and Tom reflect on the 2020 winners with Marc which vary from misophonia and narcissism to knives made of poo.