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TitreDateDurée
Lancet Haematology 10 year anniversary - meet the editors02 Oct 202400:47:21

In a special 10 year anniversary podcast, Lan-Lan Smith, Yaiza del Pozo Martin, and Emma Cookson, the editorial team behind The Lancet Haematology, reflect on the last decade and give some insights into the editorial processes at The Lancet Group.

Read our Editorial:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00289-8/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Matteo Della Porta on the phase 3 COMMANDS trial examining luspatercept versus epoetin alfa in patients with lower-risk myleodysplastic syndrome22 Aug 202400:08:08

Professor Matteo Giovanni Della Porta joins us to discuss the primary analysis of the phase 3 COMMANDS trial comparing luspatercept versus epoetin alfa in erythropoiesis-stimulating agent-naive, transfusion-dependent, lower-risk myelodysplastic syndrome patients.

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Enrico Lopriore on haemolytic disease of the fetus and newborn29 Nov 202300:12:33

Professor Enrico Lopriore joins us to discuss a trial testing darbepoetin alfa to prevent postnatal anaemia in infants with haemolytic disease of the fetus and newborn.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00285-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Meletios Dimopoulos on relapsed and refractory multiple myeloma03 Oct 202300:11:00

Professor Meletios Dimopoulos joins us to discuss two trials for patients with relapsed and refractory multiple myeloma - the first report of the DREAMM-3 phase 3 and long-term follow-up of the APOLLO phase 3 trial.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00243-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Eric Ohuma on haemoglobin concentrations and neonatal outcomes29 Aug 202300:16:27

Dr Eric Ohuma joins us to tell us about a study recently published in The Lancet Haematology on the association between maternal haemoglobin concentrations and maternal and neonatal outcomes.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00170-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Margaret Ragni on tranexamic acid to treat heavy menstrual bleeding31 Jul 202300:13:13

Professor Margaret Ragni joins us to discuss the VWDMin study, published in The Lancet Haematology. In this phase 3, randomised, crossover trial, recombinant von Willebrand factor and tranexamic acid are used to treat heavy menstrual bleeding in patients with mild and moderate von Willebrand disease in the USA.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00119-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Oreofe Odejide and Thomas Kuczmarski on mental health and lymphoma03 Jul 202300:16:32

Dr Odejide and Dr Kuczmarski tell us about a study recently published in The Lancet Haematology on the effect of pre-existing mental health conditions on survival in patients with diffuse large B-cell lymphoma.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00094-7/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Alok Srivastava on fitusiran for patients with haemophilia A and B29 Mar 202300:18:41

Professor Alok Srivastava tells us about two clinical trials being published in The Lancet and The Lancet Haematology on a new siRNA therapy called fitusiran for patients with haemophilia A and B.

Read the two trials:
Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH)
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00284-2/fulltext?dgcid=buzzsprout_icw_podcast_buzzsprout_general

Fitusiran prophylaxis in people with severe haemophilia A or haemophilia B without inhibitors (ATLAS-A/B)
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00037-6/fulltext?dgcid=buzzsprout_icw_podcast_buzzsprout_general

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Emmanuela E Ambrose on stroke prevention in children with sickle cell disease02 Mar 202300:11:31

Dr Emmanuela E Ambrose tells us about the SPHERE trial on hydroxyurea dose escalation for primary stroke prevention in children with sickle cell disease in Tanzania

Read the full article:
Hydroxyurea with dose escalation for primary stroke risk reduction in children with sickle cell anaemia in Tanzania (SPHERE)

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Sumit Gupta on racial and ethnic disparities in leukaemia survival outcomes30 Jan 202300:22:10

Dr Sumit Gupta discusses how racial and ethnic disparities affect survival outcomes of children and young adults with acute lymphocytic leukaemia.

Read the full article:
Racial and ethnic disparities in childhood and young adult acute lymphocytic leukaemia

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Xiao-Jun Huang on cellular therapy in China28 Nov 202200:28:10

Professor Xiao-Jun Huang discusses this Lancet Haematology series on Cellular Therapy in China, covering the history, current research challenges, and future of HSCT and CAR T-cell therapies in China.

Read the Series papers:
Cellular therapy in China

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Glenn Pierce on haemophilia care in LMICs30 Aug 202200:34:55

Dr Glenn Pierce discusses the World Federation of Hemophilia’s Humanitarian Aid Program which provides access to haemophilia care in low-income and lower-middle-income countries.

Read the full Review:
Achieving access to haemophilia care in low-income and lower-middle-income countries

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Kim Linton on follicular lymphoma07 Aug 202400:09:48

Dr Kim Linton joins us to discuss the EPCORE NHL-1 trial testing monotherapy with the bispecific antibody epcoritamab for patients with relapsed or refractory follicular lymphoma.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00166-2?dgcid=buzzsprout_tlv_podcast_generic_lanhae

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Amy DeZern on the link between myelodysplastic syndrome and autoimmune disorders30 Jun 202200:12:50

Dr Amy DeZern discusses the link between myelodysplastic syndrome and autoimmune disorders and the need for a multidisciplinary approach for the treatment of patients who have both.

Read the full article:
Myelodysplastic syndrome and autoimmune disorders: two sides of the same coin?

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Nicholas Crombie and Gavin Perkins on resuscitation with blood products compared with saline07 Mar 202200:15:05

Dr Nicholas Crombie and Professor Gavin Perkins discuss their randomised phase 3 trial in which they investigated resuscitation with blood products compared with saline in patients with trauma-related haemorrhagic shock receiving prehospital care. 

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Fredrik Schjesvold on OCEAN phase 331 Jan 202200:12:24

Dr Fredrik Schjesvold discusses the results of the OCEAN phase 3 trial testing melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide.

Read the full article:
Melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide (OCEAN)

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Jacob D Soumerai and Andrew D Zelenetz on the BOVen regimen for previously untreated patients with chronic lymphocytic leukaemia25 Nov 202100:11:59

Dr Jacob D Soumerai and Prof Andrew D Zelenetz discuss their phase 2 trial of the BOVen regimen and MRD-driven treatment discontinuation in previously untreated patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00307-0/fulltext 

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Raul Cordoba on haematological malignancies in older people03 Nov 202100:16:24

Dr Raul Cordoba discusses the joint Series between The Lancet Healthy Longevity and The Lancet Haematology on haematological malignancies in older people.

Read the full article:
A comprehensive approach to therapy of haematological malignancies in older patients

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Obiageli Nnodu and Dennis Chao on child mortality from sickle cell disease in Nigeria21 Sep 202100:09:03

Professor Obiageli Nnodu and Dr Dennis Chao join acting Deputy Editor Emma Cookson to talk about their new study describing modelling of child mortality as a result of sickle cell disease in Nigeria. 

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00191-5/fulltext

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Zuguo Mei and Gary Brittenham on iron deficiency27 Jul 202100:08:34

Senior Assistant Editor Ben Burwood speaks with Dr Zuguo Mei (Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA)  and Dr Gary M Brittenham (Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY, USA) about their work defining physiologically based serum ferritin thresholds for iron deficiency.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00168-X/fulltext

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Eugenia Trigoso Arjona (in English) on nursing and haematological care11 May 202100:28:34

To mark International Nurses Day, Eugenia Trigoso Arjona, nurse coordinator at Hospital La Fe (Valencia, Spain) and chair of the European Society for Blood and Marrow Transplantation Nurses Global Education Committee, joins acting Editor-in-Chief Yaiza del Pozo Martin to discuss how nurses can reshape the future of haematological care. 

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Eugenia Trigoso Arjona (in Spanish) on nursing and haematological care11 May 202100:29:11

Para el Día International de la Enfermera, Eugenia Trigoso Arjona, enfermera coordinadora en el Hospital La Fe (Valencia, España) y presidenta del comité de educación de la European Society for Blood and Marrow Transplantation Nurses hablo con la Editora Yaiza del Pozo Martin sobre como las enfermeras pueden remodelar el futuro de la hematología. 

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Nada Hamad on inclusion and diversity in haematology23 Feb 202100:30:02

A/Prof Nada Hamad (St Vincent’s hospital, Sydney, Australia) joins Editor-in-Chief Dr Lan-Lan Smith to discuss inclusion and diversity in haematology-oncology and transplantation. 

 

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Judy Truong on ferritin reference levels and iron deficiency05 Aug 202400:11:17

Dr Judy Truong join us to discuss ferritin reference intervals and how adoption of evidence-based ferritin clinical decision limits can help clinicians detect and treat iron deficiency, minimising propagation of related health inequity and social injustice in medicine.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00103-0?dgcid=buzzsprout_tlv_podcast_generic_lanhae

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Dr Judith Boer on lymphoblastic leukaemia in children22 Dec 202000:10:24

Editor-in-Chief, Dr Lan-Lan Smith, speaks with Dr Judith Boer (Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands) about outcome of ABL-class acute lymphoblastic leukaemia in children in the pre-tyrosine kinase inhibitor era.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(20)30353-7/fulltext

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Imatinib for paediatric leukaemia15 Dec 201800:08:33

Andrea Biondi joins The Lancet Haematology to discuss his work on imatinib as a treatment for paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia.

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Predicting the risk of adenoviraemia31 Aug 201800:04:51

Prashant Hiwarkar joins The Lancet Haematology to discuss his new paper, an investigation into whether serial faecal PCR monitoring can predict the risk of adenoviraemia and survival outcomes after HSCT.

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Adverse events in haematological malignancies12 Jun 201800:12:31

Lead author Gita Thanarajasingam joins The Lancet Haematology to discuss the new Commission on assessment and adverse event reporting in haematological malignancies.

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EPO blood doping and cycling: The Lancet Haematology: June 29, 201730 Jun 201700:08:34

Jules Heuberger talks about his study on the effectiveness of EPO use by cyclists.

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Trauma-induced coagulopathy: The Lancet Haematology: June issue03 Jun 201700:09:10

Petra Innerhofer discusses reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma.

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Childhood leukaemia survival (CONCORD-2): The Lancet Haematology: April 11, 201712 Apr 201700:05:46

Audrey Bonaventure discusses her CONCORD-2 study, monitoring survival trends of two types of childhood leukaemia in 53 countries between 1995 and 2009.

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Superficial-vein thrombosis: The Lancet Haematology: February 15 201716 Feb 201700:10:27

Jan Beyer discusses the SURPRISE trial of patients developing complications from superficial-vein thrombosis.

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Economic burden of blood disorders in Europe: The Lancet Haematology: July 21, 201621 Jul 201600:09:32

Dr Jose Leal discusses a study of the costs related to malignant and non-malignant blood disorders in Europe in 2012.

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Castleman disease: The Lancet Haematology: March 17, 201618 Mar 201600:17:14

David Fajgenbaum discusses a literature review to raise awareness of idiopathic multicentric Castleman disease, a poorly understood haematological disorder.

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Johannes Schetelig on remission induction versus immediate allogeneic HSCT for patients with AML16 Jul 202400:14:11

Professor Johannes Schetelig joins us to discuss the results of the ASAP phase 3 trial comparing remission induction with immediate allogeneic haematopoietic stem cell transplantation for patients with relapsed or poor responsive acute myeloid leukaemia.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00065-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Deep-vein thrombosis: The Lancet Haematology, October 29, 201530 Oct 201500:08:23

Walter Ageno discusses the use of an algorithm combining limited and whole-leg compression ultrasonography to diagnose deep-vein thrombosis.

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Financial toxicity: The Lancet Haematology: September 17, 201517 Sep 201500:06:06

Scott Huntington discusses the financial toxicity of oncology treatments

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Idiopathic thrombocytopenic purpura: The Lancet Haematology: July 29, 201529 Jul 201500:06:24

James Bussel discusses a study looking at treatment options for children facing idiopathic thrombocytopenic purpura.

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INWORKS: The Lancet Haematology: June 29, 201529 Jun 201500:06:36

Klervi Leuraud discusses a study reporting on the risk of developing leukaemia and lymphoma in workers monitored for radiation exposure.

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Warfarin: The Lancet Haematology: May 26, 201526 May 201500:12:05

Páll Önundarson describes a new method for monitoring clotting in patients treated with warfarin, which they tested in a non-inferiority, randomised clinical trial.

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Atrial fibrillation and NOACs: The Lancet Haematology: April 2, 201502 Apr 201500:09:12

Mahmoud Zureik discusses risk of bleeding in patients with non-valvular atrial fibrillation who switched and those who remained on a vitamin K antagonist.

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1 million stem cells: The Lancet Haematology: February 27, 201527 Feb 201500:13:20

Dietger Niederwieser and Richard Lane discuss the journey to 1 million haematopoietic stem cell transplantations.

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The Lancet Haematology: January 7, 201507 Jan 201500:10:14

Guillermo Garcia-Manero discusses a phase 1/2 study on sequential azacitidine and lenalidomide in high-risk MDS and AML.

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The Lancet Haematology: December 1, 201402 Dec 201400:11:02

Gregory Kato discusses a phase I study for the treatment of leg ulcers for people with sickle-cell disease.

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Banu Aygun on sickle cell anaemia23 May 202400:11:13

Professor Banu Aygun joins us to discuss the REACH trial testing hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00078-4?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Sabine Braat and Katherine Fielding on haemoglobin thresholds to define anaemia01 Mar 202400:18:06

Dr Sabine Braat and Dr Katherine Fielding join us to discuss their study presenting new haemoglobin thresholds for defining anaemia.

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https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00030-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Elisabeth Schorb on the MARTA phase 2 trial29 Feb 202400:09:23

Doctor Elisabeth Schorb joins us to discuss the MARTA phase 2 trial, treating older, fit patients with primary diffuse large B-cell CNS lymphoma with high-dose chemotherapy and autologous stem-cell transplantation.

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https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00371-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Stephan Ehl on paediatric autoimmune lymphoproliferative immunodeficiencies31 Jan 202400:13:03

Professor Stephan Ehl joins us to discuss a prospective observational study on paediatric autoimmune lymphoproliferative immunodeficiencies.

Read the full article:
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00638-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanonc

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Dr Sarah O'Brien on the PREVAPIX-ALL trial20 Dec 202300:13:50

Dr Sarah O'Brien joins Lan-Lan Smith to discuss results of the phase 3 PREVAPIX-ALL trial, which compares direct oral anticoagulant apixaban to low-molecular-weight-heparin for the prevention of venous thromboembolism in children with newly diagnosed acute lymphoblastic leukaemia or lymphoma.

Read the full article:
https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00314-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae

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Paolo Strati on off-the-shelf induced pluripotent stem-cell-derived natural killer-cell therapy for patients with relapsed or refractory B-cell lymphoma01 Jul 202500:21:49

Associate Professor Paolo Strati (Department of Lymphoma and Myeloma, and Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA) joins us to discuss the results of a multicentre, open-label, phase 1 clinical trial of off-the-shelf induced pluripotent stem-cell-derived natural killer-cell therapy for patients with relapsed or refractory B-cell lymphoma.

Read the full article:

https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(25)00142-5/fulltext?dgcid=buzzsprout_icw_podcast_July_25_lanhae

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