In this episode Hamilton sits down with Dr. Casey Paleos to discuss his psychiatric and medical training, his path to involvement in the MAPS MDMA clinical trials, and his impressions of the 2024 FDA rejection of MDMA for therapeutic use in the treatment of PTSD.

drpaleos.com

innermost.one

Note: This episode was originally released on Patreon in August of 2024.

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Hamilton speaks with Dr. Rick Strassman about his latest book "My Altered States" and together they explore other topics including the history of DMT research, consciousness, the future of psychedelic research and much more!

This episode originally aired on Patreon January 2025.
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Get Dr. Rick Strassman's latest book "My Altered States" here:
https://www.rickstrassman.com/store/my-altered-states/

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Recorded after a mushroom foray at this year's Mycofest, I sit down with Alan Rockefeller to discuss Psilocybe taxonomy, wood lover's paralysis, the enigma strain, and fungal accumulation of heavy metals.

Alan's website: https://www.mycena.llc/

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Top Tree Herbs Kratom Tea Bags - https://www.toptreeherbs.com 
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Get access to 75+ patreon exclusive podcast episodes at patreon.com/hamiltonmorris.

Chapters:
00:00:00 - Introduction
00:02:05 - Theme
00:02:26 - What is your pharmahuasca methodology?
00:12:15 - Are 4-hydroxytryptamines hydrolyzed?
00:24:40 - Why is P2P a controlled substance?
00:35:54 - What do you think of LSD licenses?
00:39:57 -  What do you make of the Dr. John Mack's work on alien abduction?
00:49:49 - Can psychedelics be used as cognitive enhancers?
00:56:44 - Are shared hallucinations real?
01:00:33 - Chemistry ASMR?

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In this podcast I interview friend and adult actress Janice Griffith about drug use and the adult entertainment industry. Enjoy!

(Originally release on April 12, 2023 at https://www.patreon.com/HamiltonMorris )

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An interview with infamous undercover LAPD "dope cop" Frank Lyga about his career tracking clandestine PCP synthesists.

A big thank you for supporting my content: 

Sheath Underwear - https://sheathunderwear.com 
Use the code "Hamilton" to get 15% off.

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This is a great and far-ranging discussion with chemist and neuroscientist Dr. Andrew Gallimore about his continuous DMT infusion project (DMTx) and his new book Reality Switch Technologies. Enjoy!

https://www.buildingalienworlds.com/

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An interview with chemist and steroid researcher Patrick Arnold, the man behind DMAA, The Clear, and many other drugs that permanently changed the world of body building and competitive sports.

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In this podcast I discuss the limits of YouTube Chemistry, chemistry TikTok houses, and selenium chemistry with Josiah "That Chemist"

https://www.youtube.com/@That_Chemist

https://mobile.twitter.com/That_Chemist

https://www.nytimes.com/1998/11/29/magazine/lethal-chemistry-at-harvard.html

I want to extend a special thanks to this episode’s sponsor https://cannaclear.com 
Use the code "Hamilton" to get 15% off.

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For the first time the pseudonymous author of the 1973 clandestine chemistry classic "Psychedelic Chemistry" is interviewed about his motivations for writing the book, his own experience with psychedelic chemistry, his relationships with the Shulgins, and his later interest in 3D technology and philosophy.

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A never before told tale of multi-ton MDA synthesis in the 1980s. Guided by a mysterious Monsanto chemist gone rogue, our interviewee embarked on a quest to synthesize vast quantities of MDA.

Subjects discussed include: Differential MDA enantiomer psychopharmacology, chocolate LSD cat food, and Raney nickel.

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The greatest living psychedelic chemist Dr. David E. Nichols tells the story of his life in research while synthesizing a novel lysergamide

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I talk with ethnomycologist Cullen Clark about his work describing two new Psilocybe species in Southern Africa and becoming the first outsider to observe and describe the use of Psilocybe species in African traditional medicine. Clark also provides an extended analysis of African cave art depicting mushroom use.

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In 1971 Charles Innes was entrapped, tricked into overdosing on PCP, brutalized by the Baltimore Police Department, and then mocked by journalists. For the first time Charles Innes tells the story of how he lost his vision. The uncut two hour interview audio is available on https://www.patreon.com/HamiltonMorris/

I want to extend a special thanks to this episode’s sponsor https://cannaclear.com Use the code "Hamilton" to get 15% off.

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https://www.apolloneuro.com/

(There IS a discount code. If you want to get 10% off you can use the code: HAMILTON)

PDFs and accompanying papers can be found at Podcast 51 on https://www.patreon.com/hamiltonmorris

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In this interview I talk with the great medicinal chemist Dr. Robert Oberlender, he is the inventor of the multi-billion dollar blockbuster drug vyvanse and a ten year veteran of the David E. Nichols laboratory responsible for the synthesis and evaluation of a number psychedelics and empathogens such DOsB, DOiB, MDAI, and many others. 

The Ian Parker article I mentioned about the embittered ambien inventor:

https://www.newyorker.com/magazine/2013/12/09/the-big-sleep-2

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This week the DEA officially withdrew their intention to prohibit five psychedelic tryptamines, this is the inside story of the legal battle behind the success featuring the great lawyers John Hunter and Matt Zorn. 

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A far-ranging discussion with one of the greatest contributors to the science of psychedelics, this is a good one!

Website for the upcoming Ethnopharmacologic Search for Psychoactive Drugs. https://espd55.com/ (Note: This website appears to be under construction)

Dr. McKenna's academy website. https://mckenna.academy/

Online Amazonian biocultural archives https://biognosis.mckenna.academy/

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This is a conversation with the cannabinoid-specializing medicinal chemist and pharmacologist Dr. Sam Banister of SDB-001 fame, we discuss his career in cannabinoid chemistry and his new venture to design psychedelic treatments for depression. 

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Initially hoping to discuss the mechanics of how a drug is made illegal, I instead have a far-reaching discussion about drug policy with one of the greatest living experts on the subject. 

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An interview 14 years in the making, for the first time the true story of the penis envy mushroom is told. Many apocryphal origin stories have been disseminated (sometimes by me) now, for the first time, the true story of how the most potent cubensis strain was created is told. 

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Please enjoy this conversation between Drs. Chris McCurdy, Brian Pearson, and Oliver Grundmann about new research on kratom and how it became one of the only substances to evade prohibition after being proposed for placement in schedule I.

If you liked this, watch/listen to my original conversation with Dr. Oliver Grundmann - https://youtu.be/npVkYGk1dJo

To participate in Dr. Oliver Grundmann's ongoing kratom tea survey with partner Top Tree Herbs, go here: https://tinyurl.com/Kratomteasurvey

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In this podcast I interview a former organometallic chemist named Mike Roberts who conducted underground research on DMT, DET, DiPT, DOM, 2C-B, and mescaline while working as a graduate student at UCLA. After a year of continuous psychedelic use his studies ended when began to confuse reality with a dream. I've attached one of Mike Roberts chemistry publications below. 

LINK TO PAPER

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A clandestine chemistry interview unlike any other, this is the story of a man whose chemistry education was paid for by an organized crime ring. After learning the necessary skills, he was tasked with synthesizing increasingly large quantities of MDA under ever-rising pressure until the entire operation exploded.

100s of unreleased episodes available at patreon.com/hamiltonmorris
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Website: https://pgorman.com/
Trip info and donation: gormanexpeditions.com/
First description of P. bicolor use in 1925: https://erowid.org/references/refs_view.php?ID=9053

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In this episode Jason Wallach and I discuss the strange origin of the head twitch response and how it became the most important behavioral correlate for 5HT2A agonism in non-human animals.

Paper: Permanent alteration of behavior in mice by chemical and psychological means

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I don't usually interview people involved with the distribution side of psychedelics, but this conversation touches on so many fascinating topics in the history of LSD that I thought other people might find it interesting. The conversation covers Steve Jobs, Kary Mullis, ergotamine tartrate, LSD distribution, and SARS-CoV-2. 

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In one of the strangest episodes to date,  Dr. D.C.A. Hillman explains the ancient ingredients in the Theriac and the practice of using children as drugs.

D. C. A. Hillman earned his Ph.D./M.A. in Classics and M.S. in Bacteriology from the University of Wisconsin

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The first of two interviews about the Kentucky ibogaine program, this discussion is with the lawyer Bryan Hubbard, the former Chairman and Executive Director of the Kentucky Opioid Abatement Advisory Commission. We discuss the tremendous opposition the program faced for political, pharmaceutical, and social reasons and his efforts to ensure ibogaine is made available to those struggling with opioid use disorder. 

Part two available on https://www.patreon.com/posts/pod-109-dimitri-108869460.

https://www.wbryanhubbard.com/

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In this episode I speak with a chemist named Tarik Peterson who authored an unusually sophisticated clandestine chemistry manual in 1970 and conducted self-experiments with a variety of different psychedelics he synthesized including DMT, DET, pyr-T, aMT, 5-MeO-DMT, mescaline, MDA, PMA, TMA, TMA-2, and TMA-6

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A big thank you for supporting my content: 

Kykeon Analytics - https://www.kykeonanalytics.com
A fully anonymous mail-in drug checking lab service.


Cannaclear alternative cannabinoids - https://cannaclear.com 
Use the code "Hamilton" to get 15% off.


Lucy Tobacco-Free Nicotine - https://www.lucy.co
Lucy's mission is to reduce tobacco-related harm to zero: use the code "Hamilton"


Matcha.com - https://matcha.com
Andrew Weil MD's matcha tea, it's delicious! Use the code "Hamilton" for up to 20% off + a FREE gift.


Top Tree Herbs Kratom Tea Bags - https://www.toptreeherbs.com 
Top Tree Herbs products are 15% off if you use the code "Hamilton"


New Brew Euphoric Seltzer - https://www.drinknewbrew.com
Use the code "Hamilton" for 15% off

_____________________________________

00:00:00 Unveiling the Mystery of a Lost Psychedelic Manual
00:03:25 The Enigmatic Alchemist: Tarek Peterson's Hidden Legacy
00:06:21 Unraveling the Psychedelic Chemistry of the 60s and 70s
00:11:01 Kykeon Analytics
00:22:30 Cannaclear.com
00:30:39 The Evolution of Psychedelic Synthesis: From Labs to Nature
00:32:37 Lucy Nicotine
00:36:37 Exploring the Impact of Psychedelics on Chemistry and Culture
00:44:45 Matcha Kari
00:54:28 Top Tree Herbs and New Brew
00:55:02 Unveiling Drug Testing Scams
00:56:36 The Journey from Chemistry Undergrad to Public Health
00:58:11 Graduate Studies and the Quest for Iron
00:59:46 Navigating the Academic Job Market: Challenges and Changes
01:00:19 Transition to Industry: A New Chapter
01:01:09 Exploring the Psychedelic Scene in Berkeley
01:08:51 The Quest for New Psychoactive Compounds
01:18:22 Reflections on a Life in Chemistry
01:31:46 The Ethical Dilemmas of a Chemist
01:51:30 A Look Back: The Impact of Psychedelic Research

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In this episode I talk with historian and drug researcher Norman Ohler about his past research on Nazi use of methamphetamine and his new book about his mother's use of LSD to help alleviate symptoms of Alzheimer's disease.

https://www.normanohler.de/

(The Kykeon Analytics - https://www.kykeonanalytics.com/ - ad had a mistake in which I said that results are made publicly available for harm reduction purposes. In fact, Kykeon orders samples from different NPS vendors and posts the results on their site, which is really interesting and I recommend checking out. To be clear, however, your submissions to them are completely anonymous and will be reported to you alone.)

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In this interview I talk with lawyer Jordan S. Rubin about his new book Bizarro, which chronicles the work of two synthetic cannabinoid entrepreneurs who found themselves ensnared in a law so confusing the DEA's own experts can't agree on how it should be interpreted.

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An earlier version of this was age-restricted on Youtube. I've edited the podcast to make it available to a wider audience. If you are interested in watching the uncensored version, you can find it on my patreon page: patreon.com/hamiltonmorris

This is the first of a series of Amanda Feilding interviews I hope to release in the coming months. We discuss her self-trepanation, LSD research, and her film "Heartbeat in the Brain."

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A big thank you for supporting my content: 

Cannaclear - https://cannaclear.com 
Use the code "Hamilton" to get 15% off.


Sheath Underwear - https://sheathunderwear.com
Sporting a micturition aperture! Use the code "Hamilton" to get 30% off.


Lucy Tobacco-Free Nicotine - https://www.lucy.co/
Lucy's mission is to reduce tobacco-related harm to zero: use the code "Hamilton"


Matcha.com - https://matcha.com/
Andrew Weil MD's matcha tea company. Use the code "Hamilton" for up to 20% off + a FREE gift.


Top Tree Herbs Kratom Tea Bags - https://www.toptreeherbs.com 
Top Tree Herbs is the first kratom tea bag company, use the code "hamilton" for 15% off

Support the show

In this episode I sit down with Dave Manheim, host of the Dopey podcast, to talk about his experiences interviewing Nick Reiner in the years before he allegedly killed Rob Reiner and Michele Singer Reiner. We discuss addiction, the film Being Charlie, and the psychological concept of self-handicapping.

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100s of unreleased episodes available at patreon.com/hamiltonmorris
Merchandise available at hamiltonmorris.com
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In this episode I sat down with chemistry educator and pseudoscience debunker Dave Farina of the popular YouTube channel Professor Dave Explains. We discuss the threat of disinformation, how to promote truth while reducing polarization, and wokescold-edgelord dialectics.
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100s of unreleased episodes available at patreon.com/hamiltonmorris
Merchandise available at hamiltonmorris.com
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A big thank you for supporting my content: 

Amentara - https://www.amentara.com
A source for Amanita muscaria, kanna, kava, akuamma, and all your other ethnobotanical needs. Use discount code "HAMILTON" for 22% off!

Lucy Tobacco-Free Nicotine - https://www.lucy.co
Lucy's mission is to reduce tobacco-related harm to zero!
Use discount code "HAMILTON"

Matcha.com - https://matcha.com
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Use discount code "HAMILTON" for up to 20% off + a FREE gift!

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In this episode I sit down with a self-taught legend of underground MDMA synthesis and former Hive member named MethylMan. We discuss Wacker oxidation, reductive amination, aluminum amalgamation and the joys and dangers of underground chemistry.
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100s of unreleased episodes available at patreon.com/hamiltonmorris
Merchandise available at hamiltonmorris.com
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Kykeon Analytics - https://www.kykeonanalytics.com
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MUD\WTR - Start your new morning ritual & get 20% off your subscription or one-time purchase at https://mudwtr.com/HAMILTONMORRIS
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Lucy Tobacco-Free Nicotine - https://www.lucy.co
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Andrew Weil MD's matcha tea, it's delicious!
Use discount code "HAMILTON" for up to 20% off + a FREE gift!

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In this episode I speak with Joel Stanley, co-founder of Charlotte’s Web, about the political battles and innovative development of high-CBD, low-THC medical cannabis. Joel is now the founder and CEO of AJNA BioSciences, a clinical-stage biotech company developing FDA-approved botanical drugs from psychedelics and cannabinoids to treat mental health and neurological disorders.
_______________
100s of unreleased episodes available at patreon.com/hamiltonmorris
Merchandise available at hamiltonmorris.com
_______________
A big thank you for supporting my content:

Kykeon Analytics - https://www.kykeonanalytics.com
A fully anonymous mail-in drug checking lab service.

Lucy Tobacco-Free Nicotine - https://www.lucy.co
Lucy's mission is to reduce tobacco-related harm to zero!
Use discount code "HAMILTON"

Matcha.com - https://matcha.com
Andrew Weil MD's matcha tea, it's delicious!
Use discount code "HAMILTON" for up to 20% off + a FREE gift!

Support the show