Explorez tous les épisodes du podcast Sharp Waves: ILAE's epilepsy podcast
| Titre | Date | Durée | |
|---|---|---|---|
| Practice guideline on outcomes after in utero exposure to anti-seizure medications: Dr. Alison Pack | 28 Oct 2024 | 00:23:41 | |
A recent practice guideline provides updated evidence-based conclusions and recommendations regarding in utero effects of anti-seizure medications and folic acid supplementation on the prevalence of major congenital malformations, adverse perinatal outcomes, and neurodevelopmental outcomes. Dr. Parthvi Ravat interviewed Dr. Alison Pack about the guideline, which was produced by the American Academy of Neurology, American Epilepsy Society, and Society for Maternal-Fetal Medicine. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Changing the term for "epilepsy" in Malaysia: Why and how? Dr. Chong Tin Tan | 14 Oct 2024 | 00:11:48 | |
Some historic names for epilepsy have been derogatory and stigmatizing. An older term for “epilepsy” in Malay means “mad pig disease.” Neurologists in Malaysia collaborated to change the word to a medically accurate term. Sharp Waves spoke with Dr. Chong Tin Tan about the origins of the older term and how the new term was introduced. Resources: Announcement of a new Chinese name for epilepsy - Lau - 2011 - Epilepsia Renaming Korean epilepsy: Where are we? - Epilepsy & Behavior Overcoming the stigma of epilepsy in Asia // International League Against Epilepsy Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Consensus recommendations for epilepsy with eyelid myoclonia (Jeavons syndrome): Dr. Kelsey Smith | 10 Jun 2024 | 00:23:03 | |
A recent publication outlined areas of consensus on the recommended management, treatment options, and prognosis for epilepsy with eyelid myoclonia, also known as Jeavons syndrome. Dr. Alina Ivaniuk interviewed Dr. Kelsey Smith about the results and how consensus was reached. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Developmental and epileptic encephalopathies: Managing more than seizures - Dr. Scott Demarest | 27 May 2024 | 00:29:15 | |
Besides seizures, people with developmental and epileptic encephalopathies experience a wide variety of symptoms, including sleep problems, vision problems, and behavioral issues. Dr. Scott Demarest discusses how neurologists may be able to address some of these, improving outcomes and quality of life. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Seizure action plans as educational tools: Dr. Lucretia Long | 13 May 2024 | 00:21:01 | |
Seizure action plans can help people with epilepsy manage their seizures and address emergencies. They often are aimed at a subset of people with epilepsy, particularly children. Dr. Lucretia Long discusses how seizure action plans can be used to engage and educate all people with epilepsy, as well as their families and the larger community. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| The Human Intracerebral EEG Platform and the power of big data: Dr. Philippe Ryvlin | 29 Apr 2024 | 00:26:26 | |
What is the Human Brain Project and how might it advance epilepsy research? Dr. Maryam Nouri speaks with Dr. Philippe Ryvlin about the project in terms of the Human Intracerebral EEG Platform and how compiling these unique data from around the world could lead to new breakthroughs and understanding of epilepsy. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Reproductive health counseling in adolescents with epilepsy: Dr. Elizabeth Harrison and Dr. Laura Kirkpatrick | 15 Apr 2024 | 00:21:26 | |
Counseling of teens and young adults with epilepsy about reproductive issues is not happening often enough. Conversations about pregnancy are almost non existent. Sharp Waves spoke with authors of a recent paper that details these findings and discusses possible solutions. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Changing epilepsy care through entrepreneurship: Dr. Mark Cook | 01 Apr 2024 | 00:23:25 | |
People with epilepsy don't always know when they have had a seizure - and yet establishing seizure frequency is a key part of epilepsy management. When Dr. Mark Cook's father was diagnosed with epilepsy, Dr. Cook realized that a system to identify and predict seizures could improve care and change people's lives. Dr. Parthvi Ravat talks with him about entrepreneurship in epilepsy and ways to advance the field through innovation. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Maximizing health-related quality of life after pediatric epilepsy surgery: Dr. Mary Lou Smith | 18 Mar 2024 | 00:24:38 | |
Is surgery for pediatric epilepsy "worth it"? What factors determine quality of life in families with a child who has epilepsy? Dr. Kette Valente talks with Dr. Mary Lou Smith, whose work has implications for clinical treatment decisions, as well as expectations for the impact of treatments in children with epilepsy. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Clinical neurophysiology training: The present and the future - Dr. Sandor Beniczky | 04 Mar 2024 | 00:15:07 | |
EEG training varies within countries as well as between them; in many countries, there is no training available. Dr. Bruna Nucera talks with Dr. Sandor Beniczky about the present and future of clinical neurophysiology training, including a recent review that calls for harmonizing this type of training across the globe. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Neonatal seizures: Guidelines and consensus-based recommendations: Dr. Ronit Pressler | 19 Feb 2024 | 00:24:48 | |
Seizures are common in neonates, but there is substantial management variability. The Neonatal Task Force of the International League Against Epilepsy (ILAE) developed evidence-based recommendations about anti-seizure medication management in neonates in accordance with ILAE standards. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Bringing epilepsy out of the shadows: How far have we come? Dr. Edward (Ted) Reynolds | 05 Feb 2024 | 00:25:15 | |
In the 1990s, there was more funding for leprosy research in the United Kingdom than for epilepsy research. It was around that time that Dr. Edward (Ted) Reynolds, then president of ILAE, recognized that as a global problem, epilepsy required global solutions. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Global neurology: Pitfalls and purpose - Dr. Melody Asukile and Dr. Deanna Saylor | 30 Sep 2024 | 00:28:08 | |
With all the best intentions, undertakings in global neurology can include assumptions and biases that lead to unforeseen negative consequences. Sharp Waves spoke with Drs. Melody Asukile and Deanna Saylor about their recent article on the perils and pitfalls of global neurology. They discussed specific examples of some of these unforeseen consequences and talked about the ingredients for productive, ethical, and sustainable global neurology initiatives. DiBiase R et al. Evaluation of Three Cohorts of the First Neurology Postgraduate Training Program in Zambia (P4-8.001) (Neurology) Zambia League Against Epilepsy Intersectoral global action plan on epilepsy and other neurological disorders (World Health Organization) Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| "Talking about things that no one else will talk about": Torie Robinson, host of Epilepsy Sparks Insights | 22 Jan 2024 | 00:23:14 | |
For her podcast, Epilepsy Sparks Insights, Torie Robinson interviews epilepsy clinicians and scientists from around the world. Diagnosed with epilepsy at age 10, Torie is working to share knowledge with people with epilepsy, their families, and the public. Her episode topics range widely, from the biochemistry of epilepsy, to the importance of epilepsy nurses, to epilepsy as an autoimmune condition, to sexual issues. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Neurology researcher and parent advocate: Dr. Luis Oliviera and the v-ATPase Alliance | 08 Jan 2024 | 00:26:44 | |
Dr. Luis Oliviera is parent to a son with an ultra-rare developmental and epileptic encephalopathy. He's also a researcher with the Michael J. Fox Foundation. He created an organization bringing parents and researchers together to better understand his son's disorder, which is part of a group of disorders caused by rare mutations in v-ATPase genes. Dr. Oliviera was interviewed by Dr. Alina Ivaniuk. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| The Idea of Epilepsy: Dr. Phillip Pearl and Dr. Simon Shorvon | 03 Dec 2023 | 00:35:37 | |
The Idea of Epilepsy, published in 2023, covers the history of epilepsy from multiple perspectives over the past 160 years. It ends with a tantalizing question: Does epilepsy actually exist? Dr. Phillip Pearl interviews author Dr. Simon Shorvon about why and how he wrote the book and what it has to offer clinicians, researchers, and non-scientists alike. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| First seizure from sleep - What is the risk of recurrence? Dr. Elaine Pang | 20 Nov 2023 | 00:17:21 | |
Are people who have their first seizure during sleep at greater or lesser risk for future seizures, compared with people who have their first seizure when they're awake? Dr. Laurent Sheybani interviews Dr. Elaine Pang, author of a 2023 paper in Epilepsia that analyzed data from 1,312 adults visiting a first-seizure clinic. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Cannabinoids, endocannabinoids, and epilepsy: Dr. Raphael Mechoulam | 06 Nov 2023 | 00:15:30 | |
Dr. Raphael Mechoulam was an organic chemist at the Hebrew University of Jerusalem, and the father of cannabis research. His team was the first to elucidate the structure of cannabidiol, or CBD. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Autism and epilepsy: Dr. Colin Reilly and Dr. Stéphane Auvin | 23 Oct 2023 | 00:28:52 | |
Nearly one-third of people with autism also have epilepsy. Researchers aren't sure why. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Dravet syndrome and the influence of the genome: Dr. Sanjay Sisodiya | 09 Oct 2023 | 00:26:21 | |
Dravet syndrome is a rare, severe epilepsy caused by changes in a gene called SCN1A. The changes cause the gene to stop functioning normally. But not everyone with this type of genetic change develops Dravet syndrome, and people with Dravet also have a wide range of clinical characteristics, which can't be fully explained by these changes. What else is going on? We spoke with Dr. Sanjay Sisodiya about a recent publication on genomic influences in Dravet syndrome. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Attorney turned author pens an epilepsy-focused novel: Sara Staggs | 25 Sep 2023 | 00:30:20 | |
Sara Staggs was a civil rights attorney and pregnant with her second child when her doctors told her to stop practicing law: her seizures had become too frequent. Staggs' 2023 novel, Uncontrollable, fictionalizes her experiences with epilepsy and provides insight into how epilepsy affects families, careers, and relationships. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Cerebral amyloid angiopathy, seizures, and epilepsy: Dr. Brin Freund | 11 Sep 2023 | 00:21:23 | |
We'll frame today's talk around a paper recently published in the European Journal of Neurology: "The incidence and risk factors associated with seizures in cerebral amyloid angiopathy." With us today is the first author of the article, Dr. Brin Freund. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Research recap: Modified Atkins diet and health-related quality of life - Dr. Magnhild Kverneland | 28 Aug 2023 | 00:19:02 | |
Diet treatments are often used with the aim of reducing seizure frequency and severity — but they may have other benefits as well. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Epilepsy comorbidities present before diagnosis: Research recap with Remy Pugh and Dr. Chris Tailby | 16 Sep 2024 | 00:20:22 | |
Some people with epilepsy also experience memory and learning issues, as well as depression or anxiety. A small study in Australia screened people for these conditions at a first seizure clinic before any anti-seizure medications had been prescribed. Compared with a control group, the people at the first seizure clinic had higher rates of all of these cognitive and neuropsychological issues. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Statins and epilepsy: Dr. Emilio Russo & Dr. Tony Marson | 14 Aug 2023 | 00:21:29 | |
Some published data suggest that besides their effect on cholesterol, statins also may play a neuroprotective role in some neurological disorders, including epilepsy. Dr. Bruna Nucera interviews Dr. Anthony Marson and Dr. Emilio Russo about whether and how to test statins as potential anti-epileptogenic drugs. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Caring for someone with functional seizures: Shannon Guinard's story | 31 Jul 2023 | 00:14:37 | |
Functional seizures, also known as psychogenic nonepileptic seizures (PNES), resemble epileptic seizures. Unlike epilepsy, they are not prompted by any electrical activity in the brain. People with functional seizures live with stigma, stress, and emotional and financial burden — and so do their care partners. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Circadian rhythms and epilepsy Part II: Dr. Maxime Baud | 17 Jul 2023 | 00:33:38 | |
Do seizures have daily, weekly, monthly, or other rhythms? In Part 2 of our two-part series on circadian rhythms, Dr. Laurent Sheybani talks with Dr. Maxime Baud about the latest research on circadian and multidien rhythms in epilepsy. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Circadian rhythms and epilepsy Part I: Dr. Mark Quigg | 03 Jul 2023 | 00:31:59 | |
The cyclic properties of seizures have been known for more than 100 years, but does everyone with epilepsy have a seizure pattern? What can be learned from seizure diaries, RNS data, and animal models, and how can this information guide further research and clinical care? Dr. Laurent Sheybani talks with Dr. Mark Quigg about circadian rhythms in epilepsy. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| An update on SUDEP and SUDEP counseling: Dr. Suvasini Sharma | 19 Jun 2023 | 00:25:04 | |
Sudden Unexpected Death in Epilepsy (SUDEP) affects about one out of every 1.000 people with epilepsy. Despite its rarity, SUDEP is important to discuss, but some physicians are wary of having the conversations. Dr. Emma Carter spoke with Dr. Suvasini Sharma about SUDEP, why it's important to inform patients and families about it, and how to manage risk factors. The greatest risk factor for SUDEP is uncontrolled generalized tonic-clonic seizures (previously called grand mal seizures). Nocturnal seizures and certain comorbidities, such as developmental delay, also are risk factors. Counseling about sudden unexpected death in epilepsy (SUDEP): A global survey of neurologists' opinions Asadi-Pooya AA, et al., 2022 Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Artificial intelligence and epilepsy: Dr. Christian Bosselmann | 05 Jun 2023 | 00:35:50 | |
Discussions of artificial intelligence and ChatGPT are everywhere. How will this technology affect epilepsy research and care? What are the dangers and pitfalls, and what do we need to know when designing research studies that use AI technology? Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Neurocysticercosis and epileptogenesis: Dr. Hector Garcia | 21 May 2023 | 00:24:45 | |
Neurocysticercosis - an infection of the brain by a pork tapeworm (Taenia solium) – is one of the most common causes of seizures worldwide. People with neurocysticercosis have incidentally ingested tapeworm eggs, which are found in the feces of people who have tapeworms in their digestive systems (a condition called taeniasis). The eggs can migrate to any organ and form larval cysts; the brain is one of the most common sites. Selected publications from the Cysticercosis Working Group in Peru: Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| How and why to address medication adherence: Dr. Avani Modi and Dr. Desiree Williford | 07 May 2023 | 00:34:16 | |
Most people with epilepsy have difficulty always taking their medications as prescribed. How can clinicians and patients talk about the issue and find solutions? Sharp Waves spoke with Dr. Avani Modi and Dr. Desiree Williford, authors of a recent study on pediatric adherence in epilepsy. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Africa's plans for improving epilepsy care: Action Amos | 23 Apr 2023 | 00:21:57 | |
ILAE spoke with Action Amos, from the International Bureau for Epilepsy (IBE) about plans and strategies for improving epilepsy care across Africa. Leveraged by the Intersectoral Global Action Plan on epilepsy and other neurological disorders, four "trendsetter" countries are taking a variety of approaches to engage governments, increase public awareness, and ensure the participation of people with epilepsy in all of their initiatives. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Managing epilepsy in older adults: Dr. Loretta Piccenna & Dr. Rebecca O'Dwyer | 10 Apr 2023 | 00:20:42 | |
Dr. Anca Arbune interviews two authors of a recent critical review on managing epilepsy in the elderly, developed by the ILAE Commission on Epilepsy in Older Adults. They discuss choosing an anti-seizure medication, monitoring cognitive changes, assessing quality of life, status epilepticus, the potential of epilepsy surgery, and the need for more research. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Reflections on the life and career of Dr. Juhn Wada (1924-2023) | 02 Sep 2024 | 00:37:28 | |
Juhn Atsushi Wada was a Japanese–Canadian neurologist known for research on epilepsy and human brain asymmetry, including his description of the Wada test to assess cerebral hemispheric dominance of language function. The Wada test is the gold standard for establishing cerebral dominance and is conducted worldwide prior to epilepsy surgery. He became a pioneer in the utilization of the kindling model of epilepsy, which permitted controlled studies of the development of epilepsy in the laboratory. More information on Dr. Wada: Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Postpartum morbidity and rehospitalization in women with epilepsy: Research recap | 27 Mar 2023 | 00:24:54 | |
Dr. Bruna Nucera interviewed Dr. Andrea Cheng-Hakimian about a retrospective study that included 28 years of data from women with epilepsy who gave birth in Washington State. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Moving epilepsy care closer to home: Dr. Gagandeep Singh & Dr. Meenakshi Sharma | 13 Mar 2023 | 00:29:40 | |
Can we improve epilepsy outcomes by bringing care closer to home? A cluster randomized trial compared home care with community health workers to standard clinic care. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Epilepsy care in Ukraine: Dr. Olha Tychkivska | 27 Feb 2023 | 00:35:20 | |
How has the crisis in Ukraine affected people with epilepsy and their families, as well as the physicians who care for them? Dr. Alina Ivaniuk speaks with Dr. Olha Tychkivska about the volunteer efforts to provide anti-seizure medication to people in Ukraine, as well as Ukrainians who fled to other countries. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| "Living with epilepsy should not be a secret": Jessie Nyirenda | 13 Feb 2023 | 00:14:09 | |
Jessie Nyirenda's seizures began in her early teens. She was dismissed as attention-seeking and told she might be cursed. Years later, Jessie discovered information about her condition through library research and was formally diagnosed. She now works as a financial educator and is a mother of three children. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Addressing epilepsy stigma from the ground up: Mary Secco | 13 Feb 2023 | 00:18:49 | |
Stigmatizing people with epilepsy is a form of discrimination, and it can affect all aspects of someone's life: school, family life, work, friendships, relationships, and marriage. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Sleep and epilepsy: Dr. Birgit Frauscher | 30 Jan 2023 | 00:28:26 | |
Bidirectional links between epilepsy and sleep have been known for thousands of years. Despite nearly a century of research using EEG investigations, the relationships are still not well understood. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Dr. Andres Kanner: A career journey bridging neurology and psychiatry | 09 Jan 2023 | 00:33:08 | |
Dr. Andres Kanner is one of the best known researchers in the behavioral aspects of epilepsy, and has authored more than 300 papers and book chapters. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Multi-centre Epilepsy Lesion Detection (MELD) Project: Dr. Konrad Wagstyl | 13 Dec 2022 | 00:19:18 | |
Improving lesion detection in people with drug-resistant epilepsy is crucial for optimal surgical outcomes. The MELD Project is an open-science consortium using deep learning principles to develop automated lesion detection of clinical MRI data. Dr. Maryam Nabavi Nouri spoke with Dr. Konrad Wagstyl about the project, publications, progress, and goals. Currently, the MELD project has three ongoing themes:
Twitter: @meld_project Website: MELD Project Publications: Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study (2021, Epilepsia) Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study (2022, Brain) Networks Underlie Temporal Onset of Dysplasia-Related Epilepsy: A MELD Study (2022, Annals of Neurology) Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Career development profile: Dr. Caroline Neuray | 29 Nov 2022 | 00:37:47 | |
Dr. Alina Ivaniuk talks with Dr. Caroline Neuray about her career path from medical school to industry CEO. (It's not as direct as it sounds!) They discuss the power of peer mentoring, ways to improve medical education, finding the courage to accept change, and what's up with those comments from reviewer #2, anyway. Dr. Neuray is Chief Executive Officer of Epilog, which offers advanced EEG analysis to support clinical care, clinical trials, and research. She received her MD from the University of Munich and completed neurology training at Paracelsus Medical University in Salzburg, with a clinical fellowship in epilepsy at University College London. Dr. Neuray also completed an MBA short course at the London School of Economics. She is a founding member of ILAE's Young Epilepsy Section (YES) and a former YES regional representative (Europe). She serves on several ILAE committees. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| NORSE/FIRES: International recommendations for diagnosis and treatment | 14 Nov 2022 | 00:22:06 | |
First-line immunotherapy and the ketogenic diet are two main recommendations for treatment of NORSE/FIRES of unknown cause, according to results from an international consensus group published in Epilepsia.
Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Astrocytes and epilepsy: Dr. Peter Bedner | 19 Aug 2024 | 00:23:46 | |
Previously thought to be mere connective tissue and support for neurons, astrocytes are now understood to have many functions in the nervous system that are linked with seizures and epilepsy. Dr. Cecilie Nome spoke with Dr. Peter Bedner about astrocytes' involvement in epilepsy and how identifying and resolving astrocyte dysfunction is a new frontier in drug development. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Nursing in epilepsy care: Roles, value, and the road ahead | 01 Nov 2022 | 00:33:24 | |
Nurses have been called the "glue" of epilepsy care, but their value and impact aren't always appreciated. The ILAE Nursing Section welcomes nurses from every country to help advocate for a better understanding of what nurses do, how their care improves outcomes in people with epilepsy, and how nurses can contribute to the goals of the Intersectoral Global Action Plan for Epilepsy and other Neurological Diseases (IGAP). Research links: Epilepsy Specialist Nurses: The Evidence (the ESPENTE study) (2019 - Campbell F et al.) Benefits of the epilepsy specialty nurse role, standardized practices and education around the world (2019 - Prevos-Morgant M et al, Revue Neurologique) A 2022 report by Epilepsy Consortium Scotland that highlights the importance of epilepsy nurse services during the pandemic Contact us with feedback or episode ideas at podcast@ilae.org. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Research recap: Infant motor and mental development in women with epilepsy - Dr. Sanjeev Thomas | 18 Oct 2022 | 00:16:26 | |
Does in utero exposure to anti-seizure medication affect motor and mental development? A study using data from the Kerala Registry of Epilepsy in Pregnancy included more than 1,300 infants. Those exposed to valproate monotherapy, as well as any polytherapy, had higher risks of developmental delay. Other epilepsy pregnancy registries: Australian Register
Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Epilepsy and Alzheimer's disease: Dr. Andrew Cole & Dr. Alice Lam | 04 Oct 2022 | 00:31:46 | |
What are the associations between Alzheimer's disease and epilepsy? Dr. Patricia Saletti interviews Dr. Andrew Cole and Dr. Alice Lam. Noninvasive Detection of Hippocampal Epileptiform Activity on Scalp Electroencephalogram – Abou Jaoude M, et al. (JAMA Neurology 2022) Towards a coherent view of network hyperexcitability in Alzheimer’s disease – Lam et al. (Brain 2022) Neuronal synchrony abnormalities associated with subclinical epileptiform activity in early-onset Alzheimer’s disease – Ranasinghe KG, et al. (Brain 2022) Effect of Levetiracetam on Cognition in Patients with Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial Vossel K et al. (JAMA Neurology 2021) Association of epileptiform abnormalities and seizures in Alzheimer disease – Lam et al. (Neurology 2020) New Approaches to Studying Silent Mesial Temporal Lobe Seizures in Alzheimer's Disease – Lam et al. (review, Front Neurol 2019) Biomarker definitions and their applications – Califf RM (Exp Bio Med, 2018) Silent hippocampal seizures and spikes identified by foramen ovale electrodes in Alzheimer's disease – Lam AD et al. (Nature Medicine 2017) Neuronal activity regulates extracellular tau in vivo - Yamada K et al. (J Exp Med 2014) Neuronal activity regulates the regional vulnerability to amyloid-β deposition – Bero AW et al. (Nat Neurosci 2011) Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||
| Career development profile: Dr. Meriem Bensalem-Owen | 19 Sep 2022 | 00:27:00 | |
Dr. Alina Ivaniuk interviews Dr. Meriem Bensalem-Owen about growing up in Algeria, attending medical school during a civil war, moving to the United States for training, and starting Kentucky's first epilepsy fellowship program. Dr. Bensalem-Owen directs the epilepsy program at the University of Kentucky and is a past board member of the National Association of Epilepsy Centers. She is passionate about Brazilian jiu jitsu and Argentine tango, and doesn't get enough sleep. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice. | |||