Explorez tous les épisodes du podcast Science@UH
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| Decoding the Immune Response to Tuberculosis | 15 oct. 2026 | 00:21:46 | |
Stephen Carpenter, MD, PhD, discusses the challenges of preventing and treating TB as well as the limitations of current vaccines, the role of memory T cells in controlling infection, and promising discoveries that could shape the next generation of tuberculosis vaccines.
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| Ovarian Tissue Transplants Provide New Hope to Women with Ovarian Insufficiency | 17 sept. 2026 | 00:23:53 | |
University Hospitals Reproductive Endocrinology and Infertility specialists, Rebecca Flyckt, MD, and Kathryn Coyne, MD, discuss a groundbreaking FDA-approved clinical trial exploring ovarian tissue transplantation between sisters. They explain how the procedure works, who may benefit and how this innovative approach could restore fertility, hormone function and hope for women facing early menopause.
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| Protecting Memory After TBI and in Alzheimer’s – New Hope from 15-PGDH | 20 août 2026 | 00:21:27 | |
Discover how a target identified in colon cancer research led to an unexpected opportunity to protect brain cells and preserve cognition in mouse models of Alzheimer’s and head trauma. Sanford Markowitz, MD, PhD, and Andrew Pieper, MD, PhD, describe the translational path, mechanistic insights into neuroinflammation and neurogenesis, and what’s needed for human trials.
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| Common Doesn’t Mean Normal: Rethinking Urinary Incontinence Care | 16 juil. 2026 | 00:22:55 | |
Adonis Hijaz, MD and Goutham Rao, MD discuss the reasons why urinary incontinence is underreported and actionable strategies clinicians can use to start the conversation in primary care. They outline the EMPOWER model, from large-scale screening to nurse navigators and pelvic floor physical therapy, and why that pathway increases treatment rates.
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| From Lab to Life: Expanding the Power of CAR T-Cells | 18 juin 2026 | 00:28:58 | |
Explore the rapidly evolving world of CAR T-cell therapy and how scientists are reengineering the immune system to fight disease. Drs. David Wald and Reshmi Parameswaran discuss breakthroughs in cancer immunotherapy, including faster manufacturing, next‑generation CAR T-cell design, and efforts to expand these therapies from blood cancers to solid tumors and autoimmune diseases. This conversation highlights the promise and challenges of bringing these innovative treatments to patients.
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| From GLP-1 to Triple Agonists: Transforming Cardiometabolic Care | 21 mai 2026 | 00:22:04 | |
The pace of change in cardiometabolic medicine is accelerating. Ian Neeland, MD, breaks down the latest innovations in incretin therapies, from oral medications to cutting-edge combinations, and what they mean for weight loss, heart health, and long-term patient care.
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| Breaking Into the Brain: Overcoming Barriers to Understand Autism and Brain Tumors | 16 avr. 2026 | 00:31:03 | |
Matthew Anderson, MD, PhD, and Tyler Miller, MD, PhD, discuss how immune biology is reshaping neuroscience - from autism and obesity to CAR T cell therapies for glioblastoma and the challenge of crossing the blood brain barrier.
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| The Science of Smell: AROMA Testing and Brain Health | 19 mars 2026 | 00:18:19 | |
Jennifer Villwock, MD, explains the neurocircuitry of smell, her rapid essential-oil–based AROMA test, and how olfactory dysfunction can inform clinical care and research spanning sinonasal disease, post-viral loss, and cognitive health.
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| Scrolling, Stress and the Teenage Brain: How EEG Biomarkers and Self-Management Can Change the Story | 19 févr. 2026 | 00:24:34 | |
Molly McVoy, MD, dives into the mental health crisis affecting teens, why anxiety and depression have risen dramatically, and shares breakthrough research using EEG biomarkers and self-management programs that help teens build resilience.
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| A Regional Powerhouse for Cancer Discovery and Patient Impact | 15 janv. 2026 | 00:30:29 | |
Theodoros Teknos, MD, and Gary Schwartz, MD, discuss how the recent $25.5 million NCI grant renewal solidifies Case Comprehensive Cancer Center as a powerhouse consortium delivering cutting-edge clinical trials, early detection and community-focused cancer prevention across Northeast Ohio.
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| Inside the Mind of a Leader: What’s Next for Infectious Disease Medicine? | 18 déc. 2025 | 00:30:10 | |
Join Dr. Daniel Simon as he interviews Dr. Igho Ofotokun, Chair of the Department of Medicine at University Hospitals. Dr. Ofotokun shares his remarkable journey from Nigeria to becoming an expert in HIV research, revealing how passion and experiences shaped his career in infectious diseases. Discover the pivotal moments that guided him in the fight against not just HIV, but also the challenges posed by COVID-19.
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| Engineering Movement with Neural Interfaces and Next-Generation Neuroprosthetics | 18 sept. 2025 | 00:16:23 | |
Stanley Bazarek, MD, and Jennifer Sweet, MD, discuss the latest advances in neuromodulation, peripheral nerve surgery, and neuroengineering, highlighting the critical role of multidisciplinary collaboration between UH, Case Western Reserve University, and national research partners in translating these innovations from the lab to patient care.
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| Advancing Heart Failure Research Across Borders | 21 août 2025 | 00:23:55 | |
Varun Sundaram, MD, PhD, discusses how his experiences shaped his groundbreaking work in global heart failure research, from uncovering international differences in patient care to leading studies on GLP-1 therapies and advanced heart failure.
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| When Proteins Go Rogue: The Prion Paradigm in Neurodegenerative Disease | 17 juil. 2025 | 00:16:47 | |
Neuropsychiatrist Brian Appleby, MD, discusses prion diseases, including Creutzfeldt-Jakob disease, and the groundbreaking research and clinical trials at University Hospitals aimed at better understanding these rare but fatal neurodegenerative conditions.
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| De-Escalation, Genomics and Multidisciplinary Care Redefines Breast Cancer Treatment | 19 juin 2025 | 00:25:22 | |
Amanda Amin, MD, Janice Lyons, MD and Alberto Montero, MD, explore the evolution of breast cancer treatment. The discussion highlights how personalized care, clinical innovation and compassionate teamwork are transforming patient outcomes.
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| Transforming Valve Therapy from Research to Real-World Application | 15 mai 2025 | 00:17:37 | |
Guilherme Attizzani, MD, shares his inspiring journey beginning as a research fellow in intravascular imaging and rising to become a national and international leader in structural heart disease interventions.
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| Neuroscience in Motion: Exploring Vision Cognition and Brain-Boosting Power of Exercise for Parkinson's | 17 avr. 2025 | 00:20:16 | |
Aasef Shaikh, MD, PhD, a leading neurologist at University Hospitals discusses his journey into neurology, his groundbreaking research in neuro-ophthalmology, movement disorders, and the application of AI-driven exercise therapy for Parkinson’s disease.
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| Strengthening Infection Control and Vaccine Effectiveness to Improve Public Health & Hospital Safety | 20 mars 2025 | 00:16:45 | |
Elie Saade, MD, MPH, Medical Director of Infection Control at University Hospitals, explains the critical role of infection prevention in healthcare, discusses strategies for reducing hospital-acquired infections, and the impact of interdisciplinary collaboration.
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| Uncovering the Mycobiome: Fungi, Gut Health, and Disease | 20 févr. 2025 | 00:17:30 | |
Professor Mahmoud Ghannoum, a leading expert in medical mycology and microbiome research, shares his pioneering work on the role of fungi in the microbiome and groundbreaking research on the mycobiome’s impact on health, including its role in gut disorders, autism, and cancer.
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| Optimizing Physical Performance through Regenerative Therapy and Innovative Technology | 16 janv. 2025 | 00:21:15 | |
James Voos, MD, and Jacob Calcei, MD explore the impact of osteoarthritis, highlighting their team's pioneering work in regenerative therapies to revolutionize musculoskeletal care, and how they collaborate with wearable technology experts to prevent sports injuries and optimize athletic performance.
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| Unlocking Prostate Cancer Screening and Genetic Insights on Aging | 18 déc. 2024 | 00:15:29 | |
Jonathan Shoag, MD, discusses his innovative prostate cancer research aiming to better understand the impact of PSA screening and his groundbreaking work on the genetics of aging.
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| Harnessing AI and Patient-Centered Research to Advance Female Pelvic Floor Health | 21 nov. 2024 | 00:15:40 | |
David Sheyn, MD, shares his unique career journey to the field of urogynecology, where he now leads innovative research to advance women’s pelvic health through personalized care, AI and cutting-edge technology.
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| Strengthening Pediatric Care Readiness: Expanding Resources and Standards to Save Lives | 17 oct. 2024 | 00:16:44 | |
UH Rainbow Babies & Children's Charles Macias, MD, MPH, discusses his work leading a $48 million grant to improve pediatric disaster readiness, emphasizing the importance of everyday preparedness, national investments in pediatric care, and the significant impact of quality improvement initiatives through structured interventions.
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| Visionary Leadership, Innovation and Clinical Research Transform the Future of Ophthalmology | 19 sept. 2024 | 00:14:33 | |
Jonathan Lass, MD, an expert in corneal transplantation and imaging, shares insights into the groundbreaking work of the UH Eye Image Analysis Reading Centers, advancements in treating various eye conditions and the future of eye care.
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| Interprofessional Synergy: Transforming Radiology with MR Fingerprinting | 15 août 2024 | 00:21:34 | |
Chaitra Badve, MD and Dan Ma, PhD discuss the collaborative relationship aimed to develop and use MR fingerprinting to transform clinical care.
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| Redefining Stroke Therapy: A Paradigm Shift Across the Globe | 18 juil. 2024 | 00:15:47 | |
Internationally renowned neurologist, Amrou Sarraj, MD, led an international study that is breaking new boundaries with stroke therapy. Listen to how the SELECT2 trial is paving the way for changing stroke therapy worldwide.
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| Visionary Innovations: Advancing Pediatric Eye Care with Technology & Education | 20 juin 2024 | 00:17:24 | |
Faruk Orge, MD, shares his remarkable journey from clinician to discovery innovator through groundbreaking innovations in pediatric ophthalmology, from AI-driven diagnostics to cutting-edge gene therapies and virtual reality training platforms, aimed at preventing childhood blindness and enhancing global eye care.
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| Navigating the Gap: Diabetes Support in Emerging Adulthood | 16 mai 2024 | 00:14:17 | |
Julia Blanchette, PhD, RN, discusses her research on empowering young adults with Type 1 diabetes. From navigating the complexities of health insurance to addressing financial stress, discover how her work is making a difference in diabetes management.
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| Female Sexual Health: Barriers and Roadmap to Optimal Outcomes and Treatments | 18 avr. 2024 | 00:19:29 | |
Sheryl Kingsberg, PhD describes the evolution of female sexual health studies, today’s treatments for female sexual health disorders and a new and upcoming treatment for post-partum depression.
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| Navigating Complex Mechanisms of HPV+ Head and Neck Cancers | 21 mars 2024 | 00:18:23 | |
Quintin Pan, PhD, explores the surge of HPV+ related head and neck cancers sparking the need for innovative treatment solutions.
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| LimFlow Technology Redefines Biology: Reverses Blood Flow to Prevent Limb Amputations | 15 févr. 2024 | 00:16:00 | |
Mehdi Shishehbor, DO, PhD, explains how his team is developing preventative solutions to overcome chronic limb-threatening ischemia.
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| EsoCheck™ & EsoGuard™: Revolutionary Invention Transforms Esophageal Cancer Diagnostics | 18 janv. 2024 | 00:25:06 | |
Amitabh Chak, MD, Sanford Markowitz, MD, PhD, and Joseph Willis, MD, explain the journey of EsoCheck™ and EsoGuard™, an incredible bench to bedside diagnostic discovery to detect Barrett's esophagus and prevent esophageal cancer. | |||
| Connecting the Mind and Body through Evidence-Based Integrative Modalities | 15 déc. 2023 | 00:16:36 | |
Francoise Adan, MD, and Samuel Rodgers-Melnick, MPH, MT-BC, discuss how Connor Whole Health’s research of how music therapy reduces pain, stress and anxiety and how these modalities can be implemented for patient care. | |||
| Physician Scientist Carries on Legacy of UH Rainbow in Neonatal Care | 16 nov. 2023 | 00:16:53 | |
Cynthia Bearer, MD, explains how her groundbreaking research on fetal alcohol spectrum disorder, lipid rafts, and brain development in preterm babies aims to improve neonatal care. | |||
| Transforming Patient Outcomes through Radiology Partnerships and AI Solutions | 19 oct. 2023 | 00:19:35 | |
Leonardo Kayat Bittencourt, MD, discusses how the University Hospitals Radiology AI and Diagnostic Innovation Collaborative, RadiCLE, is collaborating with innovative teams to use AI application to investigate clinical practices in hope of bringing new solutions to improve patient care and outcomes. | |||
| Exploring the Effects of Policy and Environmental Factors on Health Outcomes | 21 sept. 2023 | 00:22:34 | |
Sanjay Rajagopalan, MD discusses how historical government policies impact health outcomes more than 90 years later and the need to understand external and internal environments to transform the delivery of healthcare. | |||
| Discovery of Protein S-nitrosylation Leads to Creation of Oxygen and Nitric Oxide Exercise Monitor | 17 août 2023 | 00:20:59 | |
Jonathan Stamler, MD discusses what lead him to the discover of S-nitrosylation, the binding of nitric oxide to proteins works through allostery and how this all lead to the creation of an oxygen and nitric oxide tracking fitness monitor. | |||
| Neuropsychiatric Research Advances Self-Management Programs for Neurological Disorders | 20 juil. 2023 | 00:14:10 | |
Martha Sajatovic, MD explains how her research has led to a self-management program for patients with epilepsy and science to service models for other neurological conditions. | |||
| From Bench to Bedside: Non-Small Cell Lung Cancer Discovery Creates Hope | 15 juin 2023 | 00:19:51 | |
Afshin Dowlait, MD describes how his team of researchers discovered a new non-small cell lung cancer subtype in the laboratory and brought a new treatment for this cancer subtype to patients in a clinical trial. | |||
| Restoring Hearing Loss through Scientific Advancement | 18 mai 2023 | 00:16:30 | |
Endoscopic ear surgeon and pioneer, Alejandro Rivas, MD, discusses why he is driven to advance science for patients with hearing loss, the latest advances in cochlear implant surgery and his clinical trials aimed to prevent hearing loss in children and adults. | |||
| Community-Engaged Research Combats Breast Cancer and Prostate Cancer | 20 avr. 2023 | 00:26:24 | |
Cynthia Owusu, MD and Randy Vince, MD discuss how they were inspired through their medical and personal experiences to become physician-scientists who help to improve the social determinants of health and health disparities for African American men and women with prostate and breast cancers. | |||
| Research Discoveries Boost Personalized Treatment for IBD | 16 mars 2023 | 00:16:04 | |
Fabio Cominelli, MD discusses how his team of researchers discovered the specific blockade of interleukin-18 can reduce disease severity in colitis and new personalized therapies to put IBD in permanent remission. | |||
| Balanced, Healthier Lives with the Science of CINEMA | 16 févr. 2023 | 00:22:39 | |
Sadeer Al-Kindi, MD and Ian Neeland, MD discuss CINEMA, a center of excellecence that advances clinical excellence, promotes team science, and impacts the standard of care for patients with cardiometabolic disease. | |||
| COVID-19: What We Have Learned and Still Need to Discover | 19 janv. 2023 | 00:24:10 | |
Grace McComsey, MD, Vice President of Research and Associate Chief Scientific Officer at University Hospitals discusses how University Hospitals acted fast and became a vital academic center during the pandemic to better understand the COVID-19 virus and treatments through a multitude of clinical and research studies. | |||
| The Integrated Medical Environment: Using AI to Translate Big Data to Precision Medicine | 15 déc. 2022 | 00:20:51 | |
Led by Michael DeGeorgia, MD and Kenneth Loparo, PhD, a $1.2 million JobsOhio grant will help establish the Center for Connected Health Innovation to enhance precision medicine in the ICU. | |||
| Pediatric Type 1 Diabetes & Daily Management | 17 nov. 2022 | 00:15:03 | |
Rose Gubitosi-Klug, MD discusses pediatric type 1 diabetes and the evolution of standard care and daily management. | |||
| A Promising Pancreatic Cancer Discovery | 19 oct. 2022 | 00:18:30 | |
Jordan Winter, MD discusses his research breakthroughs to identify a metabolic enzyme, IHD1, in pancreatic cancer and how this led to finding a drug developed for other cancers that can also target this wild-type enzyme of pancreatic cancer. | |||
| From MMA Fighter to Radiation Oncologist: Combating Prostate Cancer | 20 sept. 2022 | 00:15:06 | |
Daniel Spratt, MD discusses the obstacles of prostate cancer and shares breakthroughs and achievements. | |||