Hosted by JD Denham and Will Haas, The Peptide of The Week Podcastis your no-BS guide to peptides, performance, and total body optimization. Whether you’re an athlete, a high performer, or just hungry to feel better, move better, and live stronger this show’s for you. JD and Will dive deep into real-world protocols, hard-earned lessons, and the science behind what actually works. With expert guests and raw conversations, you’ll get everything from cutting-edge peptide talk to diet, training, recovery, and mindset. No fluff. No filters. Just the tools to rebuild your body and upgrade your life.
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Peptide of the Week: GLP-1 Breakdown – Semaglutide vs Tirzepatide vs Retatrutide
Saison 1 · Épisode 80
lundi 23 mars 2026 • Durée 48:42
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas break down one of the hottest topics in health right now GLP-1 compounds and the real differences between Semaglutide, Tirzepatide, and Retatrutide.
From how these peptides actually work in the body to why some people feel terrible on certain ones and thrive on others, this episode gives you a real-world, no-BS explanation of what’s going on under the hood.
Chapters:
00:00 – Intro & Hair Talk
01:01 – Podcast Growth & Mission
03:04 – Discipline & Six Pack Mindset
06:36 – Sobriety, Learning & Growth
08:22 – Fear of Failure vs Growth
10:42 – Celebrating Hard Work
11:50 – GLP-1 Breakdown (Basics)
14:57 – How GLP-1 Works (Fat Loss)
19:59 – Semaglutide Explained
22:30 – Tirzepatide Explained
24:30 – Retatrutide Explained
29:01 – Dosage & Protocols
34:48 – Side Effects & Relationships
40:10 – Which One Should You Take
42:14 – Lifestyle Still Matters
We cover:
🧬 How GLP-1 peptides actually work
– GLP-1 is a naturally occurring hormone that signals fullness
– Normally lasts 5–10 minutes after eating
– These compounds extend that signal to days instead of minutes
– Reduce hunger, slow gastric emptying, and regulate blood sugar
Peptide Q&A #33 – Marathon Prep on TRT/HGH, NAD vs NMN, Melanotan Side Effects & Prostate Issues
Saison 1 · Épisode 79
jeudi 19 mars 2026 • Durée 59:34
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week’s Peptide Q&A, JD Denham and William T. Haas break down real-world questions on endurance training with peptides, NAD optimization, tanning peptides, prostate health, nerve pain, and dialing in fat-loss compounds like SLU-PP-332.
From marathon prep while on TRT and HGH, to troubleshooting AOD stinging, to understanding why some compounds hit people differently this episode is packed with practical insight from years of hands-on experience.
Chapters:
00:00 – Intro & Platform Update
02:03 – Podcast Origins & Learning Process
07:14 – TRT, HGH & Marathon Prep
12:43 – NAD vs NMN/NR Explained
18:44 – Melanotan 1 vs 2
24:18 – TRT Decision (Feel vs Numbers)
28:41 – Prostate, Low Test & Solutions
34:22 – SLU-PP-332 Dosing Debate
41:28 – First Responder Optimization Stack
47:09 – Severe Back Pain & Surgery Talk
52:29 – MK-677, Prolactin & Growth
Topics covered in this episode include:
• Marathon Prep on TRT + HGH – optimizing recovery, managing bodyweight, and why 1 IU of HGH may be enough for endurance training
Peptide of the Week: TRT, HCG & Growth Hormone – The Foundation of Men’s Health
Saison 1 · Épisode 70
lundi 16 février 2026 • Durée 55:01
We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Dr. Tyler from Action TRT to break down the real root of modern men’s health decline low testosterone and the foundational protocols that are changing lives: TRT, HCG, and Growth Hormone.
From why testosterone levels are crashing in younger men to the truth about estrogen, fertility, libido, and long-term optimization, this episode is a masterclass in building the hormonal base that everything else depends on.
Chapters:
00:09 Intro & Why Testosterone Is So Low Today
02:40 How a Proper TRT Clinic Evaluates New Patients
06:15 Total vs Free vs Bioavailable Testosterone Explained
11:00 HCG: Fertility, Testicular Function & Mental Benefits
16:45 Enclomiphene vs HCG (What Actually Works Long Term)
22:30 TRT Dosing Mistakes & The AI/Estrogen Debate
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week’s Peptide Q&A, JD Denham and William T. Haas open up with gratitude, growth, and real talk about discipline then dive deep into hormone issues, peptide stacking, libido struggles, and practical injection strategies. No fluff. No scripts. Just experience.
42:29 Wolverine Stack: Dosing for Maintenance vs Injury
46:29 TRT Libido Issues & Hormone Troubleshooting
58:54 CJC/IPA, Fat Loss Stacks & Retatrutide
1:02:29 TRT for Older Men
1:03:39 GHK-Cu Topical vs Injectable + Water Retention in Women
1:07:54 Upcoming Guests & Outro
We cover:
🔥 Back Acne on TRT: Why estrogen not DHT is usually the culprit, when (and when NOT) to use AIs, and the truth about finasteride vs dutasteride
💉 Estrogen Management: Injection frequency, SHBG, prolactin, and how poor AI timing can actually make things worse
Peptide of the Week: GH Secretagogues vs HGH – The Real Truth About Tesa, CJC, Ipamorelin & MK-677
Saison 1 · Épisode 68
lundi 9 février 2026 • Durée 44:50
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas break down one of the most misunderstood peptide categories out there: growth hormone secretagogues. From real GH to Tesamorelin to MK-677, this one is packed with nuance, strategy, and real-world results.
Chapters:
00:00 Welcome Back & Super Bowl Banter
05:50 What This Episode Covers: Growth Hormone Secretagogues
06:45 GHRH vs GHRP Explained (Simple Breakdown)
12:50 Tesamorelin: Benefits, Fat Loss & Why It’s Top Tier
15:30 CJC-1295 (With vs Without DAC)
19:20 Age, Teens & Secretagogues (Who Should Not Use Them)
23:30 MK-677: Hunger, Muscle Gain & When It Makes Sense
26:50 Dosing Strategy, Timing & Cutting vs Bulking
29:00 Tesamorelin & Sleep Issues (How to Fix It)
34:30 Secretagogues vs Real HGH (What to Use & When)
38:20 Long-Term Benefits: Recovery, Aging & Fat Loss
41:20 TRT, Estrogen, AIs & What’s Coming Next
44:10 Outro & Final Thoughts
We cover:
🧬 GH Secretagogues 101: GHRH vs GHRP
– GHRH (Tesamorelin, CJC) tells the pituitary to make GH
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors. In Peptide Q&A Episode 27, JD Denham and William T. Haas dig into real questions from real people navigating fat loss stalls, hormone optimization, endurance training, peptide stacking, and long-term health. This episode is raw, conversational, and experience-driven exactly how these Q&As are meant to be.
We cover:
🔥 GLP Plateaus After Weight Loss: Why fat loss stalls after Tirzepatide or Semaglutide, how lost muscle slows metabolism, and when switching to RETA makes sense
⚖️ RETA vs Tirzepatide Strategy: Dosing guidance, when to bump slowly, and how RETA helps preserve muscle while leaning out
💪 Fat Loss Without the Gym: How bodyweight training, fasted movement, and protein timing matter when formal workouts aren’t realistic
🧠 Secretagogues + RETA: Why running CJC/IPA or Tesamorelin alongside GLPs protects muscle and improves long-term body composition
🔥 Cardio Myths & Fat Loss: Why steps don’t equal fat loss, why lifting beats cardio, and how muscle drives calorie burn even at rest
🧬 HGH for Longevity & Body Recomp: Ideal dosing ranges (1–2 IU), why HGH is a long game, early side effects to expect, and realistic timelines
🩸 TRT at a Young Age: When bloodwork matters more than age, why 32 isn’t always “too young,” and how lifestyle impacts testosterone
⚠️ Estrogen Spikes on TRT: Symptoms of high estradiol, when to use an AI, why gyno risk is real, and how to find your personal sweet spot
🧪 RETA Dosing for Lean Athletes: Why ultra-lean individuals often need lower, microdosed RETA instead of aggressive weekly dosing
Peptide of the Week: Testosterone Esters + TRT Protocols – Hormone Optimization & Healing With Dr. Scott Collie
Saison 1 · Épisode 66
lundi 2 février 2026 • Durée 01:07:47
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this special Peptide of the Week episode, JD Denham and William T. Haas are joined by Dr. Scott Collie a long-time friend and hormone optimization expert to take a deep dive into blood work, testosterone replacement, ester differences, side effects, and proper protocol stacking.
This one’s all about optimizing hormones with real strategy. If you’re considering TRT or already on it, this is required listening.
Peptide Q&A #26 – Top 5 Peptides, Vetting Peptide Vendors, Fat Loss for Lean Women
Saison 1 · Épisode 65
jeudi 29 janvier 2026 • Durée 01:08:22
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors. In this week’s Peptide Q&A, JD Denham and William T. Haas break down a massive lineup of real-world questions covering everything from top peptide rankings and injury healing to fat loss for already-lean women, mitochondrial health, autoimmune conditions, and how to actually vet peptide vendors without getting burned. No rehearsed answers. Just experience, debate, and straight talk.
We cover:
🔥 Top 5 Peptides Explained: JD and Will rank their personal top peptides from the Wolverine stack and RETA to AOD-9604, HGH, IGF-1 LR3, MOTS-C, and NAD with real reasons behind each choice
🧬 Switching Tesa/IPA to CJC/IPA: Why it’s okay to rotate secretagogues, how long to run each, and realistic dosing ranges for men vs women
🏗️ IGF-1 LR3 Dosing & Cycling: How to properly titrate, why cycles should stay short (4–6 weeks), and what “too much” actually looks like
🧪 Peptide Vendor Red Flags: COAs, missing endotoxin testing, reconstituted peptides, fake lab reports, and why “cheap” peptides are usually cheap for a reason
⚠️ Endotoxins Explained: What acceptable levels really are, why most vendors don’t test for them, and how much risk actually exists in the real world
🔥 Rapid Fat Loss & Liver Enzymes: Why fast weight loss can temporarily elevate ALT/AST, how GLP use plays into it, and why the liver usually rebounds
💪 Fat Loss for Lean Women: Why RETA may not be ideal for already-lean females, better options like AOD + Tesamorelin, and when eating more fixes stalls
⚡ Mitochondrial Stack Strategy: MOTS-C vs SS-31 whether to run together, timing logic, dosing ranges, and why consistency matters more than sequencing
Peptide of the Week: AOD-9604 + IGF-1 LR3 – Fat-Burning Firepower & Muscle-Growth Signaling
Saison 1 · Épisode 64
lundi 26 janvier 2026 • Durée 50:00
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this powerhouse episode of Peptide of the Week, JD Denham and William T. Haas break down two of the most talked-about compounds in the game: AOD-9604, the fat-blasting fragment of HGH, and IGF-1 LR3, the muscle-building giant.
From deep dives into dosing and cycling to real-world protocols, stacks, and who should be taking what—this episode is packed with expert insight, personal anecdotes, and no-BS education for anyone trying to lose fat or build lean mass.
We cover:
🔥 AOD-9604 Breakdown
– A synthetic fragment of HGH (amino acids 177–191) that’s purely fat-burning
– No effect on IGF-1, insulin sensitivity, or muscle mass = ultra-targeted shredder
– Great for men and women, especially those coming off GLP-1s like Retatrutide
– Best stacked with: Retatrutide, SLU, 5-Amino-1MQ, or L-Carnitine
– Typical dose: 250–500mcg, 1–2x/day
– Cycle: 12–16 weeks, then rotate to another fat burner
💪 IGF-1 LR3 Deep Dive
– Long-acting form of IGF-1 (stays active for 20–30 hours)
– Directly signals lean muscle growth, nutrient partitioning, and recovery
– Bypasses pituitary, HGH, and liver—delivers pure muscle-building power
Peptide Q&A #25 – Mixing Peptides in One Vial, Bulking on RETA + AOD, Anti-Aging Stacks for Women
Saison 1 · Épisode 63
jeudi 22 janvier 2026 • Durée 50:50
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week’s Peptide Q&A, JD Denham and William T. Haas dive into another real-world round of questions from mixing protocols and fat loss stacks to bulking strategies, side effects, and safety-first decisions. No theory. Just what they’ve seen, tested, and learned the hard way.
We cover:
💉 Mixing Multiple Peptides in One Shot: How JD combines multiple peptides into one sterile vial to avoid 5 separate jabs and why glutathione should stay separate
🧪 Cloudy Syringe Warning Sign: What it means when a mix turns cloudy and when that’s your sign to stop combining certain compounds
🧠 pH Balance Debate: JD shares what a trusted source in the peptide world told him about mixing and why he doesn’t stress the “internet experts”
🍽️ Bulking on RETA + AOD: Can you gain muscle while using fat-loss peptides? Yes but only if you’re eating in a true surplus
🔥 RETA Killing Appetite While Bulking: How to push calories even when you’re full fast and why “eat past full” becomes the real skill
⚙️ Osteoporosis Stack for Mom: Tesamorelin + Ipamorelin dosing for older women, why lower doses matter, and why bedtime shots amplify results
🧬 Adding HGH for Bone Health: Why JD likes low-dose HGH for anyone over 40, and how it stacks alongside Tessa/IPA
👕 Warrior Makers Tank Tops: What’s coming soon, why the last cutoffs were way too long, and what brands they actually like
🚫 Benign Tumor + Peptides: Why both JD and Will say to cut peptides completely when tumor growth is involved even “health boosting” ones like NAD and MOTS-C
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– Why it’s called the “fountain of youth” in clinical practice
– The synergy of optimized testosterone + GH
– Performance, energy, and long-term health benefits
📊 Optimization is individualized
– There is no universal “perfect number”
– The real metric: energy, performance, recovery, libido, sleep & body composition
– Small dose adjustments that create massive quality-of-life changes
🧪 This is real clinical experience, real patient outcomes, and real protocols not forum theory.
🧠 Libido Loss on TRT: Why erections can be psychological AND hormonal, prolactin considerations, cabergoline, calming peptides, and performance anxiety
💊 Cialis Strategy: Why daily low-dose Cialis may work better than “as needed” dosing
🧬 Mixing Peptides in One Syringe: What’s safe, what’s ideal, needle dulling, scar tissue risks, and when to switch to fresh pins
🧊 Peptide Travel & Storage:** How long peptides can sit at room temp, when refrigeration matters, and what to look for in a reputable supplier
😴 DSIP Dosing: Sub-Q protocol, realistic expectations (it doesn’t knock you out), and how it enhances REM sleep
💆 Glow Serum vs Injectable GHK-Cu: Why topical formulations are different, post-laser healing benefits, and how often to apply
⚖️ Low-Dose Naltrexone: When it may help cravings or receptor sensitivity and why it’s not a magic fix for everyone
🧪 Thymalin & Adipotide: Why they’re less popular, safety concerns, and when thymosin alpha-1 is the better immune option
🚴 Wolverine Stack Dosing: Daily maintenance vs blast protocols for athletes rehabbing injuries and staying ahead of inflammation
🔥 RETA Stacking for Fat Loss: AOD, SLU-PP-332, 5-Amino-1MQ, and mitochondrial support for leaning out
👴 65-Year-Old Starting TRT: Why 197 total test at that age is a strong candidate for replacement and why quality of life matters
💧 Tesamorelin Water Retention in Women: Finding the sweet spot, dose adjustments, and why women often need much less
💋 GHK-Cu After Microneedling: Why purpose-built serums beat injectable peptides used topically
💡 Hormones are individual. Bloodwork matters. Injection frequency matters. Ego from doctors doesn’t help. Your body is a science experiment learn it.
📌 Subscribe for weekly no-fluff education, protocols, and real-world results.
You’re a warrior. Act like one.
– GHRP (Ipamorelin, MK-677, GHRP6) pushes the pulsing & release
– Why you need both sides of the equation for max effect
– Warehouse analogy explained: stock + shipping = full power
💉 Ranking the Peptides (Effectiveness vs Side Effects)
– Tesamorelin: 5/5 effectiveness, 2/5 side effects the king of fat loss & GH synergy
– Fat loss, sleep quality, muscle retention, faster recovery, skin tightening, and aging in reverse
– Plan: 1–2 IUs/day indefinitely
– JD & Will both planning to run growth long-term
– “This isn’t about youth. It’s about maximizing life.”
💬 Got questions or peptide topics you want broken down? Drop a comment below.
📺 Subscribe for more no-fluff, real science weekly.
⚡ Energy & Focus Alternatives: Why peptides won’t replace Adderall, plus real-world discussion on Modafinil, CMAX, PE-22-28, and NAD
🏃 Endurance & Hybrid Athletes: SLU-PP-332, mitochondrial peptides (MOTS-C, SS-31), Wolverine stack support, and muscle preservation for runners
🦴 Injury Prevention for Runners: Why healing peptides and GH support matter when mileage is high and joints take a beating
🧬 Tapering Off GLPs: Smart RETA tapering, appetite control during exit phases, and why Tesofensine or SLU can help bridge the gap
🧪 Peptide Blends vs Individual Stacking: Real-world results with Wolverine and Glow blends, cost efficiency, and why “perfect pH” matters less in practice
📏 Reconstitution Made Simple: Practical math for blends, vial strength breakdowns, and how JD & Will actually dose in the real world
💡 Peptides don’t replace discipline they amplify it. Diet, protein intake, sleep, hormones, and consistency still run the show.
👉 Drop your questions for the next Q&A.
📌 Subscribe for weekly Q&As, protocols, and real-world peptide education.
You’re a warrior. Act like one.
We cover:
🩸 Blood Work & Baseline Panels
– Why a comprehensive panel is essential before starting TRT or peptide therapy
– Inflammation markers, homocysteine, iron levels & clotting risks
– Common doctor mistakes: running only total testosterone with no free test or estrogen panels
– Genetic factors (MTHFR), detox pathways & why gut health matters for estrogen clearance
💉 TRT Side Effects & How to Avoid Them
– Estrogen conversion, DHT, prostate health & hair loss explained
– Common side effects (acne, gyno, fatigue, mood swings) and how to minimize them
– Natural blood thinners: fish oil, natto kinase, bergamot, turmeric
🧬 Ester Education – From Sipionate to Propionate to Sustanon
– Fast vs slow release esters explained
– When to choose Test Prop vs Sip vs Sustanon vs Enanthate vs Undecanoate
– Daily vs weekly dosing strategies & injection protocols (IM vs SubQ)
– What "PIP" (post-injection pain) means and how to reduce it (oil type, heating, MCT vs grapeseed)
🔥 Optimal TRT Dosing
– Why 200–250mg is often too much for long-term use
– Why 125–150mg/week is the true sweet spot for most men
– Expected results timeline: 3 weeks to feel it, 6 weeks to retest, 3 months to dial it in
– Monitoring lipid panels, hematocrit, ferritin, homocysteine over time
🧪 Stacking with Peptides
– Using TB-500 and BPC-157 for injury recovery (yes, even for teens)
– Thymosin Alpha-1 for immune support alongside TRT
– When to avoid stacking GH secretagogues or MK-677 in younger athletes
– Women & TRT: microdosing for libido, bone density, mood & anemia
💡 Bonus Topics
– Intramuscular vs SubQ injection effectiveness
– Mitochondrial repair: Why SS-31 should come before MOTS-C
– Why some people feel NAD or MOTS-C — and others don’t (and why that’s okay)
📌 Bottom line: Hormone optimization isn't about blasting your body. It's about strategy, testing, and long-term health. From esters to estrogens, this episode cuts through the fluff with real talk and proven science.
🧪 This isn’t hype it’s hard data, real-world feedback, and first-hand experience.
💬 Got questions or peptide topics you want broken down? Drop a comment below.
📺 Subscribe for more no-fluff, real science weekly.
🦴 Severe Tendonitis & Injury Healing: Wolverine stack dosing strategies, loading phases vs long cycles, injection placement, and when to go aggressive
🧠 Bulging Discs & Back Pain: Why peptides help inflammation but won’t fix structural disc issues and when surgery is the real solution
🧑⚕️ Vitiligo & Autoimmune Support: Peptides that may help skin pigmentation and immune balance including BPC-157, GHK-Cu, KPV, Melanotan-1, and Thymosin Alpha-1
💉 Glow Blend + Wolverine Together: How to stack BPC, TB-500, and GHK-Cu safely, daily vs weekly dosing, and copper limits
😴 Sleep, Recovery & Budget Picks: Best one-to-two peptide choices when money is tight and long-term recovery matters
💡 Peptides aren’t magic but when dosing, sourcing, nutrition, and training line up, they’re powerful tools.
👉 Drop your questions for the next Q&A.
📌 Subscribe for weekly Q&As, deep dives, and real-world protocol breakdowns.
You’re a warrior. Act like one.
– Works best when paired with heavy training volume and carbs (not for keto)
– Use post-workout, pre-big meals, or pre-workout for massive pumps
– Dose: Start at 20mcg/day, ramp to 60–80mcg max. Run for 4–6 weeks max
– Expect: Fuller muscles, faster recovery, and nutrient super-absorption
🧪 Stacking Strategies for Fat Loss & Muscle Growth
