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TitreDateDurée
Wegovy Pens Recalled & Wegovy Pill Launch06 Jan 202600:26:11

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This episode opens the year with one of the most consequential—and complicated—weeks in GLP-1 obesity medicine.

We break down three stories that, taken together, reveal why patients are increasingly reading past headlines and demanding accountability from the industry.

First, we examine early-phase trial data from Arrowhead Pharmaceuticals, after headlines claimed its experimental INHBE-targeting therapy “nearly doubled” the weight loss of Zepbound. We walk through what the data actually showed, why the comparison was misleading, how trial design and dosing matter, and why Phase 1 results should never be treated as superiority claims.

Next, we turn to a major access milestone: the official launch of oral Wegovy, the first FDA-approved GLP-1 pill for obesity from Novo Nordisk. We discuss how this pill differs from compounded oral semaglutide, why its pricing strategy is so disruptive, and what this launch means for people who have avoided injectable medications. We also explore how direct-to-consumer access, telehealth partnerships, and retail pharmacy distribution signal a broader shift in how obesity care is being delivered.

Finally, we address the most ironic—and uncomfortable—story of the week: manufacturing quality concerns involving branded Wegovy pens, reported to include biological particulate matter, at the same time Novo Nordisk continues a years-long public and legal campaign against compounded GLP-1 medications on safety grounds. We discuss FDA inspection history, the acquisition of Catalent, and why credibility depends on consistency—especially when millions of patients are paying close attention.

This episode isn’t anti-pharma or pharma-friendly. It’s patient-first.
And it asks a simple question: Who do we trust when science, marketing, access, and manufacturing all collide at once?

Episode Timestamps

00:00 — Why this first episode of 2026 matters
02:10 — Hair found in Wegovy pens and why patients notice hypocrisy
06:15 — Arrowhead trial headlines vs. what the data actually shows
11:40 — Why tirzepatide dosing and trial design matter
17:30 — What INHBE targeting may actually be good for (and what it’s not)
21:45 — Sponsor: SHED and access pathways for obesity care
25:10 — Oral Wegovy officially launches: what’s different this time
30:20 — How the Wegovy pill works and why bioavailability matters
35:40 — Pricing, telehealth, Costco, and direct-to-consumer access
41:50 — Why pills lower barriers for millions of patients
46:10 — Manu

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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Wegovy Pill Approved: First Ever GLP-1 Pill, As Good as Injections!23 Dec 202500:29:14

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📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Lower Cost Zepbound and Wegovy? TrumpRX Announcement Incoming04 Nov 202500:45:58

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📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Dr Spencer Nadolsky: Docs Who Lift Pod | OTP Eps 9015 Nov 202401:35:26

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Dr Spencer Nadolski of the “Docs Who Life” podcast joins Dave to recap obesity week, and to deep dive into Dave’s ongoing struggle with obesity and type 2 diabetes.

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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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BECOME A MEMBER:
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📺 We're Live M/W/F at 11 central: onthepen.tv


📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Novo Nordisk's War on Compound Semaglutide, Maritide Has Some Negative News12 Nov 202400:26:09

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In this episode of On The Pen: The Weekly Dose, host Dave Knapp dives into the latest updates in obesity medicine, with insightful takes on current treatment breakthroughs, new medication approvals, and tips on navigating healthcare options. This week’s deep dive also touches on emerging trends in GLP-1 therapy and how recent shifts may impact accessibility for patients. Whether you’re just starting your journey or a long-time follower of GLP-1 news, this episode brings you the essentials. ​ 

Maritide Bone Density Loss:
https://www.statnews.com/2024/11/12/amgen-maritide-obesity-drug-candidate-data/

Catalent Novo Merger:
https://www.biospace.com/deals/lilly-vs-novo-the-he-said-she-said-row-about-catalents-glp-1-work

Novo War On Compounds:
https://www.onthepen.com/post/shocking-truth-about-semaglutide-what-novo-nordisk-doesn-t-want-you-to-know

Drug Shortage Policy Reform Request (VOTE!):
https://forum.policiesforpeople.com/t/compound-tirzepatide-and-semaglutide-transparency-in-fda-drug-shortage-process-503b-protection/7821

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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
Buy Here: https://amzn.to/3Dc66d4

MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
Venmo: OnThePen
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BECOME A MEMBER:
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WATCH MORE!
📺 We're Live M/W/F at 11 central: onthepen.tv


📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Viking Therapeutics and AstraZeneca Steal The Show at Obesity Week!05 Nov 202400:29:08

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Semaglutide News: https://www.onthepen.com/post/select-trial-update-semaglutide-s-cardiovascular-benefits-and-psychiatric-safety-profile-highlighte

Viking Therapeutics News:
https://www.onthepen.com/post/vk2735-vikingtide

AstraZeneca News: 
https://www.onthepen.com/post/astrazeneca-s-azd5004-a-power-move-in-obesity-medicine

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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
Buy Here: https://amzn.to/3Dc66d4

MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
Venmo: OnThePen
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BECOME A MEMBER:
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WATCH MORE!
📺 We're Live M/W/F at 11 central: onthepen.tv


📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Lilly Earnings Call Analysis: Why Zepbound Missed Earnings31 Oct 202400:36:52

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Dave brings his analysis of the Q3 Eli Lilly earnings call, and how it relates to the future of access to obesity medicine. Also there is an important clarification on the Zepbound savings card that you should not miss.

#Zepbound #Mounjaro #Tirzepatide


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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
Buy Here: https://amzn.to/3Dc66d4

MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
Venmo: OnThePen
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BECOME A MEMBER:
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📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

New Zepbound Savings Card, GLP-1 Accessibility Landscape Evolves29 Oct 202400:17:35

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Lilly Releases 2025 Zepobound Savings Card Details:
https://www.onthepen.com/post/breaking-zepbound-savings-card-2025-released-what-you-need-to-know

Novo Nordisk Petitions FDA to Add Semaglutide to DDC list: https://www.onthepen.com/post/compound-semaglutide

Eli Lilly Petiioned FDA in Augus to add Tirzepatide to DDC list:
https://www.onthepen.com/post/compound-tirzepatide



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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
Buy Here: https://amzn.to/3Dc66d4

MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
Venmo: OnThePen
Ca$h App: ManOnMounjaro

BECOME A MEMBER:
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WATCH MORE!
📺 We're Live M/W/F at 11 central: onthepen.tv


📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Inside the Legal Battle for Compound Tirzepatide: What You Need to Know from Industry Insider Scott Brunner!25 Oct 202400:36:34

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An article on the news broken by Mr Brunner on compound Tirzepatide: https://www.onthepen.com/post/compound-tirzepatide

a4pc.org
compounding.com

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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
Buy Here: https://amzn.to/3Dc66d4

MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
Venmo: OnThePen
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BECOME A MEMBER:
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📺 We're Live M/W/F at 11 central: onthepen.tv


📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Tirzepatide Lawsuits Filed By Lilly, Catalent Reframing Novo Merger22 Oct 202400:28:44

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Lilly Lawsuits: https://www.onthepen.com/post/eli-lilly-zepbound-tirzepatide-lawsuits

Catalent Merger: https://www.businesswire.com/news/home/20241020996199/en/Catalent-Issues-Open-Letter-to-Customers-Regarding-Pending-Acquisition-by-Novo-Holdings

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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
Venmo: OnThePen
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BECOME A MEMBER:
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📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Compounded Zepbound Legal Battle Landscape: Legal Expert Weighs In18 Oct 202401:15:08

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OTP legal correspondent Lee (@LeeFitsIn) joins Dave to discuss where we stand in the legal battle over compounded versions of Zepbound and Mounjaro. (Apologies for audio, the interview was a TikTok live recording).
 
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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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BECOME A MEMBER:
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📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Compounded Zepbound Uncertainty + Leveraging GLP-1 To Improve Labor Shortages15 Oct 202400:19:20

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Zepbound Compound News:
https://www.onthepen.com/zepbound-news

New type two diabetes treatment:
https://www.upi.com/Health_News/2024/10/14/ozempic-intestinal-therapy-eliminate-insulin-Type-2-diabetics/6911728911126/

Using GLP-1  to improve workforce participation:
https://www.independent.co.uk/news/health/weight-loss-drugs-nhs-tirzepatide-mounjaro-b2629171.html

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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Heartbreaking Zepbound Story | OTP Eps 8511 Oct 202401:26:04

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OTP community member Megan a.k.a. Spoonie Megumi shares her heartbreaking journey to Zepbound.

Two of my favorite products on this journey (affiliate links below)
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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
Venmo: OnThePen
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BECOME A MEMBER:
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📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Eli Lilly Earnings Call Recap: NEW GLP-1 GIP Peptide Announced!30 Oct 202500:23:55

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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Tirzepatide Lawsuits + Ozempic Patent Victory08 Oct 202400:20:17

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Semaglutide Patent: https://www.fiercepharma.com/pharma/novos-patent-litigation-settlement-mylan-could-pave-way-cheaper-ozempic-generics

Outsourcing Facilities Association Lawsuit: https://www.reuters.com/legal/compounding-group-sues-fda-removing-lillys-weight-loss-drug-shortage-list-2024-10-07/

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Decoding GLP-1 Book
Decoding GLP-1: A Guide for Friends and Family of Those On The Pen
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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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BECOME A MEMBER:
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📲 Contact Me: dave@onthepen.com

Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Megadosing Zepbound and Mounjaro With Dr. Daniel Rosen04 Oct 202401:27:06

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Dr. Daniel Rosen talks candidly about his approach to slow responders to GLP medications in his bariatric clinic.

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Decoding GLP-1 Book
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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Ozempic and Zepbound Supply Impacted by Port Worker Strike!02 Oct 202400:19:55

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PORT WORKER STRIKE: https://www.cnbc.com/2024/10/01/port-strike-blockbuster-weight-loss-drug-supply-trade-shutdown.html

ZEPBOUND FOR NON-OBESE: https://www.ft.com/content/b2da2ca6-822e-4d42-bee4-e500522531e7

WEIGHT WATCHERS CEO OUT: https://www.bloomberg.com/news/articles/2024-09-27/weightwatchers-replaces-ceo-sima-sistani-after-stock-plummets?leadSource=uverify%20wall

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Amy Kane @AmyInHalf Discusses Dramatic Mounjaro Transformation28 Sep 202400:57:42

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Amy Kane (@AmyInHalf) joins to talk about her rise to GLP stardom, and Dave discusses all the relevant news of the week!

Aired live at 9pm central, Thursday 9/26/24.

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GLP-1 Clapback Queen Amy Kane | OTP Eps 83
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On The Pen: The Weekly Dose 9.24.2424 Sep 202400:23:45

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Metsera MET-097: https://www.fiercebiotech.com/biotech/metseras-long-acting-glp-1-shot-linked-75-weight-loss-36-days-data-sparse

Biomed Pharma NA-931: https://www.biomedind.com/NA-931.html

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Eli Lilly Compound Tirzepatide Letters + Retatrutide Trial Guest!21 Sep 202401:14:36

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We discuss the Eli Lilly letters that are going out to users of compound Tirzepatide. Mimi from the #Retatrutide trial joins! Plus our new segment maintenance minute with Korrie, where Korrie discusses all things weight maintenance!
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BCBS Demanding Refunds From Ozempic Prescribers? | The Weekly Dose 9.17.2417 Sep 202400:17:28

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Discord: https://discord.gg/QUEp5DBeNew 
New Facebook Group: https://www.facebook.com/share/g/Ab2ApGdaqRQj1T6c/

Medicare and Ozempic
https://qz.com/ozempic-price-cut-medicare-negotiations-1851650680

BCBS Demanding Payments from Off Label Ozempic Prescribers
https://www.bloomberg.com/news/articles/2024-09-12/off-label-ozempic-prescriptions-spark-1-million-demand-from-insurer

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On The Pen: The Weekly Dose 9.10.2410 Sep 202400:24:18

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Zealand News:
https://www.globenewswire.com/news-release/2024/09/09/2943004/0/en/Zealand-Pharma-announces-positive-topline-results-from-13-week-Phase-1b-multiple-ascending-dose-clinical-trial-with-GLP-1-GLP-2-receptor-dual-agonist-dapiglutide.html
Roche News:
https://www.bloomberg.com/news/articles/2024-09-09/roche-falls-as-side-effects-data-for-obesity-drug-raises-concern
Tern News:
https://www.fiercebiotech.com/biotech/terns-oral-glp-1-shows-5-weight-loss-1-month-highest-dose

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Dr. Spencer Nadolsky On Compound Tirzepatide After Leaving Weight Watchers 06 Sep 202400:42:35

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Dr. Spencer Nadolsky has announced his departure from Weight Watchers and joins Dave live for a chat about Zepbound GLP1 meds and Obesity medicine.

#WW #WeightWatchers #DrSpencer

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Ozempic Shortages Extended | The Weekly Dose 9.3.2403 Sep 202400:22:15

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Watch On The Pen Live:
onthepen.tv

GLP-1 News:
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SPONSOR:
Ro.Co/OTP

SHOW NOTES

WEGOVY REDUCES COVID DEATHS
https://www.wjbf.com/news/popular-weight-loss-drug-reduced-risk-of-covid-deaths-in-new-study/

WEGOVY REDUCES HEART DISEASE RISK BY 20%
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01498-3/fulltext

OZEMPIC SHORTAGE TO LAST THROUGH 2024
https://www.biospace.com/business/novos-ozempic-to-remain-in-shortage-into-q4-as-supply-woes-continue

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Retatrutide + Tirzepatide Grey Market Clampdown + 1 Billion GLP-1 Pills Incoming28 Oct 202500:29:41

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Zepbound Savings Card & Zepbound Vials Discussion With The Downsized30 Aug 202400:57:27

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Christopher and Laraine Durham of @TheDownsized join Dave to discuss the Zepbound vials arrival and the changes to the Zepbound savings card!

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Massive Zepbound Vials News 8.27.2427 Aug 202400:17:14

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RO TOOLS TO HELP YOU:
Ro Body: ro.co/otp
#ReportTheShortage - ro.co/supply-tracker
#OptInForObesity - See if you're covered ro.co/checker

Madison Muller Article on Zepbound Vial Pricing:
https://www.bloomberg.com/news/articles/2024-08-27/eli-lilly-is-now-selling-zepbound-weight-loss-drug-at-50-discount?srnd=undefined

Search Zepbound Pricing:
https://www.goodrx.com/zepbound/what-is

Empoloyer Form Letter to Add Obesity Coverage:
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On The Pen: The Weekly Dose 8.20.2419 Aug 202400:21:13

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VOTE FOR THE WEEKLY DOSE PODCAST!
CHECK OUT OUR SPONSOR: RO.CO/OTP

Semaglutide in Parkinsons and Opiod Abuse
https://www.wired.com/story/the-benefits-of-ozempic-are-multiplying/?

How Roche Passed on Orforglipron
https://www.swissinfo.ch/eng/multinational-companies/how-roche-passed-on-a-potential-14bn-a-year-weight-loss-pill/86877239?fbclid=IwZXh0bgNhZW0CMTEAAR1doDlsWIFXuUJYA9Kz75D9VvzZycgqm2kVbVPuWWFgOP0tvOVNvIWluVY_aem_GDMhnl8sQEVePWYy0XdheQ

Roche's Obesity Pipeline
https://www.onthepen.com/post/more-threats-to-lilly-s-tirzepatide-printing-press

Novo Announced Additional API Site
https://www.fiercepharma.com/pharma/novo-create-50-jobs-new-220m-raw-ingredients-plant-will-support-ozempic-and-wegovy

Patients Splitting Pens
https://www.theatlantic.com/health/archive/2024/08/ozempic-hackers/679464/


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On The Pen: The Weekly Dose 8.13.2413 Aug 202400:21:31

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#ReleaseTheVials
https://www.onthepen.com/post/eli-lilly-to-releasethevials-of-zepbound
Eli Lilly has released single-dose vials for ZepBound to stabilize higher dose supplies and removed all Mounjaro and ZepBound doses from the FDA shortage list, though tirzepatide remains in shortage. Novo Nordisk is seeking FDA approval for Icosema, a combination of insulin and semaglutide, with a favorable safety profile.

Lilly Sends Tirzepatide Compound Cease and Desist Letters
https://www.onthepen.com/post/it-begins-eli-lilly-fires-off-round-of-cease-and-desist-letters-to-tirzepatide-peddlers

Eli Lilly is taking legal action against GLP-1 compounders, particularly targeting ZepBound. Cease and desist letters have been issued to smaller prescribers and med spas, potentially pressuring the FDA on tirzepatide’s shortage status.

#ReportTheShortage
Ro.co/supply-tracker

Patients are encouraged to report ZepBound or Mounjaro shortages to the FDA. Ro has introduced a supply tracker tool to notify patients of nearby availability and launched RoBody, a program connecting patients with doctors to manage obesity and achieve significant weight loss.

Insurance Checker Toll
Ro.co/checker

Ro's new GLP-1 Insurance Coverage Checker allows users to check insurance coverage for obesity medications and is integrated with the supply tracker. Despite financial struggles, 23andMe is launching a GLP-1 telehealth service. The ‘Opt-in for Obesity’ campaign encourages employees to request obesity coverage from their employers.

On The Pen Live

Z Reitano from Ro will discuss the GLP-1 Insurance Coverage Tool on the upcoming On The Pen Live session, airing on YouTube this Thursday at 9 p.m. Central.

#OptInForObesity
https://www.onthepen.com/post/optinforobesity-how-petitioning-your-employer-can-break-the-barr

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On The Pen: The Weekly Dose 8.6.2406 Aug 202400:20:02

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Fortune interview:

Tirzepatide shortages (viral tiktok video with 199,000+ views):

Tirzepatide heart trial (viral tiktok video with 90,000+ views)

semaglutide pre-diabetes trial:

Weight Watchers:


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On The Pen: The Weekly Dose 7.30.2430 Jul 202400:21:50

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Book Email Alerts: https://www.onthepen.com/glp1-book
Altimmune

Novo Nordisk Expansion:

Novo Nordisk Fire:

Novo Nordisk EU Wegovy:

Roche:

Weight Watchers Resignation:

FDA and compounding:

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On The Pen: The Weekly Dose 7.23.2422 Jul 202400:17:20

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On The GLP-1 Pen Book Alerts:
https://onthepen.com/emails

Gan & Lee (China)
https://www.prnewswire.com/news-releases/gan--lee-pharmaceuticals-bi-weekly-twice-a-month-glp-1-receptor-agonist-gzr18-injection-achieved-17-29-weight-loss-at-30-weeks-in-a-phase-iib-clinical-trial-302202575.html

Mazdutide (China):
https://www.fiercebiotech.com/biotech/innovent-bags-another-phase-3-win-next-gen-lilly-glp-1-drug

China:
https://www.reuters.com/business/healthcare-pharmaceuticals/eli-lillys-weight-loss-drug-tirzepatide-gets-approval-china-2024-07-19/

Retatrutide (tiktok video):
https://www.nature.com/articles/s41421-024-00700-0

GLP-1 Temperature Monitor:
https://www.varcode.com

Eli Lilly:
https://www.bioprocessonline.com/doc/how-eli-lilly-s-making-peptides-faster-and-more-reliably-0001

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On The Pen: The Weekly Dose 7.16.2415 Jul 202400:22:18

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PBM reform in Illinois (tiktok video)

FTC on PBM

FDA and social media (tiktok video)

Patient weight-loss expectations

Wegovy commercial:

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Amylin and the future of obesity medicine with Dr. Beverly Tchang13 Jul 202400:39:47

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Dave chats with world renowned obesity expert who consults for the likes of Novo Nordisk!

Beverly Tchang, MD is a triple board-certified physician  with a focus on obesity medicine. Since 2018, she has been treating patients and training professionals in endocrinology and obesity. Her nationally recognized expertise has led her to extend her knowledge and experience as an advisor to  companies, entrepreneurs, and investors who  want to learn about modern weight management. 
BeverlyTchangMD.com
X: @bevTchangMD

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On The Pen: The Weekly Dose 7.9.2408 Jul 202400:15:57

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Ozempic reduces cancer risk:

Semaglutide correlated with blindness (tiktok video):


15-years as type-2 diabetic results in a 78% chance of have some degree of retinal eye damage

Update to Mounjaro/ZepBound FDA shortage on 7/2/2024 (tiktok video)
#releasethevials

Mounjaro KwikPen coming to Australia

  • News provided by Mimi from Australia (Mimi featured in Live #61 -- part of Retatrutide trials

GIP scientific study:

semaglutide vs. tirzepatide

Keto diet:

High-price of GLP-1 medications:

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HLTH 2025: Obesity Care Superstar Interviews22 Oct 202500:49:48

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On The Pen: The Weekly Dose 7.2.2402 Jul 202400:20:50

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Eli Lilly

Him & Hers:

Price for generic liraglutide/Victoza (multiple tiktok videos):

TROA

BI 3034701 (tiktok video):

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On The Pen: The Weekly Dose 6.25.2425 Jun 202400:19:33

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Novo Nordisk expansion in the US:
https://www.novonordisk.com/news-and-media/news-and-ir-materials/news-details.html?id=168528

Generic liraglutide
https://www.onthepen.com/post/teva-launches-first-ever-generic-glp-1-a-game-changer-for-diabetes-and-weight-management

New Wegovy Coupon:
https://www.wegovy.com/coverage-and-savings/save-on-wegovy.html

New Mounjaro Card (tiktok video)
https://mounjaro.lilly.com/savings-resources

Tirzepatide (tiktok video):
https://www.reuters.com/business/healthcare-pharmaceuticals/weight-loss-drug-zepbound-resolves-sleep-apnea-up-52-patients-lilly-says-2024-06-21/

Petrelintide
https://www.onthepen.com/post/introducing-petrelintide-discover-the-promise-of-amalyn-agonist-medications-for-weight-loss

Gut bacteria:

DACRA:
https://ir.vikingtherapeutics.com/2024-06-24-Viking-Therapeutics-Presents-Preclinical-Data-on-Novel-Dual-Amylin-and-Calcitonin-Receptor-Agonists-at-84th-Scientific-Sessions-of-the-American-Diabetes-Association

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On The Pen: The Weekly Dose 6.18.2418 Jun 202400:17:56

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PBM Reform Form Letter: 

  • Link to the Letter: https://www.onthepen.com/post/pbm-reform-form-letter-for-elected-representatives

Express scripts (tiktok video on PBM reform):

Michigan (tiktok video)

Accessibility

Vivani (tiktok)

Diet on GLP-1:

Online GLP-1s:


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Zepbound And Liver Disease12 Jun 202400:09:36

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Eli Lilly's phase 2 SYNERGY-NASH study shows tirzepatide effectively resolves MASH and improves fibrosis, offering hope for millions. Read more here: https://www.onthepen.com/post/tirzepatide-shows-promise-in-treating-mash-key-findings-from-the-synergy-nash-study

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On The Pen: The Weekly Dose 6.11.2411 Jun 202400:19:30

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Ro.co/supply-tracker

FDA shortage update (tiktok video):
Link:https://www.accessdata.fda.gov/scripts/drugshortages/dsp_ActiveIngredientDetails.cfm?AI=Tirzepatide%20Injection&st=c

EASL (European Association for the Study of the Liver) 2024 in Milan Italy
Link: https://investor.lilly.com/news-releases/news-release-details/lillys-tirzepatide-was-superior-placebo-mash-resolution-and-more
Link: https://www.biospace.com/article/mash-clash-between-lilly-and-boehringer-zealand-takes-center-stage-at-easl24/

Walgreen:
Link: https://www.benefitspro.com/2024/06/03/walgreens-will-conduct-clinical-trials-for-boehringer-ingelheims-new-obesity-drug/?slreturn=20240610103336

Kroger (tiktok video):
Link: https://www.aol.com/news/kroger-health-revamps-weight-management-132122808.html

Eli Lilly Clinical trial:
Link: https://clinicaltrials.gov/study/NCT06373146?term=tirzepatide&aggFilters=status:act%20rec&rank=6

Eli Lilly CFO:
Link: https://www.prnewswire.com/news-releases/lilly-announces-departure-of-anat-ashkenazi-chief-financial-officer-302163882.html

China:
Link: https://www.benzinga.com/news/24/06/39197516/chinese-generic-ozempic-wegovy-versions-could-put-novo-nordisk-at-the-risk-of-stiff-competition-in-k



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On The Pen: The Weekly Dose 6.4.2404 Jun 202400:17:44

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https://ro.co/weight-loss/supply-tracker
https://www.youtube.com/watch?v=mL_krAas70k

Novo Nordisk Advertising:

  • Novo Nordisk launches new advertising campaign "The Power of Wegovy"
  • This advertisement includes the new indication for reduction of cardiovascular risk
  • For 2023, the #5 advertising spend for a drug was Rybelsus at $191 million.  The #6 advertising spend was Ozempic at $187.4 million (increase of 6% from 2022). More than 40% of the 2023 ad spend for Ozempic  went to online video platforms (i.e. social media like youtube)
  • Link: https://www.youtube.com/watch?v=dhretLXYkZ4

Structure Therapeutics GSBR-1290

  • GSBR-1290 is a small molecule GLP-1 pill
  • In a 12-week phase 2 clinical study, a tablet formulation of GSBR-1290 had a weight-loss of 6.9%. This is comparable to Eli Lilly's phase 2 results for olforglipron
  • At Week 12, 67% of GSBR-1290 treated participants achieved ≥6% weight loss and 33% achieved ≥ 10% weight loss, compared to 0% for placebo
  • Also developing next generation combination GLP-1 candidates together with GIP, amylin, glucagon and apelin oral small molecules
  • Link (Madison Muller): https://www.bloomberg.com/news/articles/2024-06-03/structure-reports-early-oral-weight-loss-drug-data-adding-allure


Elon musk tweet:

  • Elon Musk tweeted: Just make a lot of Ozempic/Mounjaro. It’s not inherently expensive. The health benefits of reducing obesity far exceed the downside of GLP-1 inhibitors. We evolved under starving conditions and now make food that is plentiful and delicious. Whether that food is “processed” does matter, but is not a game changer
  • This tweet has currently been seen 325,500 times

Shanghai Stem Cell Type 2 Diabetes Treatment
https://www.scmp.com/news/china/science/article/3263878/chinese-scientists-report-world-first-they-cure-patients-diabetes-cell-therapy

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OTP EPS 68: Ro CEO Zach Reitano Talks GLP-1 Supply Tracker31 May 202401:05:22

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Zachariah Reitano is the founder of Ro, a telehealth company that has a vision of giving consumers more power over their health, he joins #OnThePen to talk all things #mounjaro #zepbound #wegovy #ozempic 

Reitano is the founder of Ro, a telehealth company that has a vision of giving consumers more power over their health.

https://ro.co/weight-loss/supply-tracker/

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On The Pen: The Weekly Dose 5.28.2428 May 202400:19:18

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On The Pen News: https://www.onthepen.com/blog

SHOW NOTES:
Ozempic study in New England Journal of Medicine:
Link: https://www.bloomberg.com/news/articles/2024-05-24/novo-s-ozempic-slashes-risk-of-death-in-kidney-disease-study

Compounding (tiktok video)
Link: https://www.abc.net.au/news/2024-05-22/compound-pharmacies-banned-weight-loss-drugs-replica-ozempic/103861108

Zealand Pharma:
Link: https://www.biospace.com/article/zealand-touts-phase-i-results-for-glp-1-glp-2-candidate-despite-modest-weight-loss-/

Inhaled GLP-1 medications
Link: https://www.biostock.se/en/2024/05/iconovo-initiates-development-of-inhaled-obesity-treatment/

Oral version of tirzepatide (tiktok video):
Link: https://ca.finance.yahoo.com/news/lexaria-awards-contract-third-glp-130500555.html

Mounjaro approved for China (tiktok video):
Link: https://www.bloomberg.com/news/articles/2024-05-21/china-clears-eli-lilly-s-weight-loss-drug-tirzepatide-only-for-diabetes

Eli Lilly announces capacity increase (tiktok video)
Link: https://investor.lilly.com/news-releases/news-release-details/lilly-increases-manufacturing-investment-9-billion-newest

GLP-1 usage by young people:
From 2020 to 2023, the number of U.S. adolescents and young adults using GLP-1 increased 600 percent — from roughly 8,700 peo

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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

On The Pen Live Eps 67: Survodutide Trial Participant Tells All!25 May 202401:18:17

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In this week’s episode of On The Pen Live, guest Scott Liberto of PlanetScott.com joins to discuss his experience in the Survodutide clinical trial.

Survodutide is an investigational dual agonist targeting both the glucagon and GLP-1 receptors, developed by Boehringer Ingelheim in collaboration with Zealand Pharma. This novel drug is designed to treat obesity and metabolic dysfunction-associated steatohepatitis (MASH). 

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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

On The Pen: The Weekly Dose 5.21.2421 May 202400:25:11

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👉 Link to other GLP-1 MUST HAVE products I mention: https://www.amazon.com/shop/manonthemounjaroonthepen

📼 PLAYLISTS:
🖊️ ON THE PEN LIVES:
https://www.youtube.com/playlist?list=PLtOcNl0C8quVdrWruYSrJpTZPF7jjXKfM
👀 WATCH MY MOUNJARO JOURNEY IN ORDER:
https://www.youtube.com/watch?v=aplFxNOv77g&list=PLtOcNl0C8quWo7PWY9j_HilhWIRuedyiO
😎 NERDS ONLY: LEARN ABOUT OTHER GLP-1 MEDS:
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SHOW LINKS:
Novo Nordisk fire:
Link: https://www.wsj.com/livecoverage/stock-market-today-dow-jones-earnings-05-16-2024/card/fire-at-novo-nordisk-construction-site-gives-investors-a-scare-eSSAtdDDhxYwUw3bGDZI?mod=lctimeline_finance

New CagriSema drug trial
Link: https://clinicaltrials.gov/study/NCT06409130

Wegovy Heart Benefits:
Link: https://www.cnn.com/2024/05/13/health/wegovy-trial-analysis/index.html

CT-488 Phase 1 Results:
Link: https://www.fiercebiotech.com/biotech/roches-27b-carmot-bet-pays-phase-1-weight-loss-success

Nothing contained in this podcast is medical advice. Please consult your liscensed p

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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

TRUMP: Ozempic Will Soon be $150 in the US! Meet the Reporter Who Made Him Say It!17 Oct 202500:29:33

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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

On The Pen: The Weekly Dose 5.14.2414 May 202400:16:12

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#Zepbound #releasethevials #mounjaro

📲 Contact Me: MounjaroMan@gmail.com
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📼 PLAYLISTS:
🖊️ ON THE PEN LIVES:
https://www.youtube.com/playlist?list=PLtOcNl0C8quVdrWruYSrJpTZPF7jjXKfM
👀 WATCH MY MOUNJARO JOURNEY IN ORDER:
https://www.youtube.com/watch?v=aplFxNOv77g&list=PLtOcNl0C8quWo7PWY9j_HilhWIRuedyiO
😎 NERDS ONLY: LEARN ABOUT OTHER GLP-1 MEDS:
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SHOW NOTES:
Update on Bernie Sander's fight against high prices for GLP-1 medicationsLink: https://www.msn.com/en-us/health/other/novo-asks-for-more-time-to-answer-sanders-on-ozempic-s-price/ar-BB1lZ0P2

CFO of Viking Therapeutics sold stock
Link: https://www.investing.conews/company-news/viking-therapeutics-cfo-sells-over-49-million-in-company-stock-93CH-3419573

Novo Nordisk bond sale (Bloomberg article):
Link: https://www.bloomberg.com/news/articles/2024-05-13/ozempic-maker-novo-nordisk-plans-bond-sale-to-fund-expansion?embedded-checkout=tru

Why companies should cover obesity mediation
Link: https://ca.news.yahoo.com/obese-people-more-likely-time-22010

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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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📺 We're Live M/W/F at 11 central: onthepen.tv


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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

Threats to Lilly's Zepbound & Mounjaro Printing Press11 May 202400:11:21

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Roche Pharmaceuticals has acquired Carmot Therapeutics along with three obesity and type 2 diabetes candidates: CT-868 / CT-368 / CT-986

MY WORK RELIES ON YOUR GENEROSITY, BECOME A MEMBER HERE:
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SOCIAL LINKS
https://www.tiktok.com/@manonthemounjaro
https://twitter.com/ManOnMounjaro
https://instagram.com/manonthemounjaro
https://facebook.com/manonthemounjaro
 
#Zepbound #Maritide #mounjaro 

📲 Contact Me: MounjaroMan@gmail.com
👉 Link to other GLP-1 MUST HAVE products I mention: https://www.amazon.com/shop/manonthemounjaroonthepen

📼 PLAYLISTS:
🖊️ ON THE PEN LIVES:
https://www.youtube.com/playlist?list=PLtOcNl0C8quVdrWruYSrJpTZPF7jjXKfM
👀 WATCH MY MOUNJARO JOURNEY IN ORDER:
https://www.youtube.com/watch?v=aplFxNOv77g&list=PLtOcNl0C8quWo7PWY9j_HilhWIRuedyiO
😎 NERDS ONLY: LEARN ABOUT OTHER GLP-1 MEDS:
https://www.youtube.com/playlist?list=PLtOcNl0C8quW-YZuu_DSpt_NS9fVQbMoW
🚨📰 ALL THE LATEST MOUNJARO NEWS:
https://www.youtube.com/playlist?list=PLtOcNl0C8quVo0I2YODK-q7cHh4y1r2yB

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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

On The Pen: The Weekly Dose 5.7.2408 May 202400:18:32

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MY WORK RELIES ON YOUR GENEROSITY, BECOME A MEMBER HERE: https://www.youtube.com/channel/UCDocQ-4IhVS3ihy_dW7nSKw/join 
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#Zepbound #Maritide #mounjaro 

LINKS 
Life Update Blog: Link: https://www.onthepen.com/post/i-m-tired-we-are-tired 

Wegovy released in Canada: 
Link: https://www.msn.com/en-ca/health/other/weight-loss-drug-wegovy-available-in-canada-starting-may-6/ar-AA1o1lZz 

Madison Muller at Bloomberg (friend of our community) had article "Why Weight-Loss Drugs Wegovy, Zepbound Are in Short Supply" 
Link: https://www.bloomberg.com/news/articles/2024-05-02/why-weight-loss-drugs-wegovy-zepbound-are-facing-shortages?srnd=undefined&embedded-checkout=true 

Interviewed on radio station KXEL 
Link: https://www.youtube.com/watch?v=V0YyMwtMuxs 

Optum RX Irony alert: 
Link: https://www.managedhealthcareexecutive.com/view/glp-1-tiering-agreement-reached-says-optum-rx-president 

FTC is challenging Novo Nordisk's patents on Ozempic 
Link: https://www.ftc.gov/system/files/ftc_gov/pdf/novo-nordisk-ozempic-saxenda-victoza-_4302024.pdf 

FTC requested additional information on Novo Nordisk's acquisition of Catalent: 
Link: https://www.msn.com/en-us/money/markets/us-ftc-seeks-more-information-on-novo-nordisk-parent-catalent-deal/ar-AA1o6gHU

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Decoding GLP-1 Book
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MY WORK RELIES ON YOUR GENEROSITY, WAYS TO SUPPORT:
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Thank you for tuning in! If you found this content valuable, make sure to like, share, and subscribe to my youtube channel for more updates on GLP-1, obesity, type 2 diabetes, and the latest news on Mounjaro, Zepbound, Wegovy, and Ozempic. Stay informed and entertained with my unique blend of breaking news, humor, and my personal journey. For in-depth articles and resources, visit onthepen.com.

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