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TitreDateDurée
Author Interview: Post-irradiation chemotherapy in patients with newly diagnosed ependymoma16 Feb 202600:17:18

Dr. Jasmin Jo interviews Dr. Amy Smith and Dr. David Ellison on their manuscript, entitled "Phase 3 randomized trial of post-irradiation chemotherapy in patients with newly diagnosed ependymoma, a report from the Children's Oncology Group" published in Neuro-Oncology in December 2025.

Hot Topics: How longitudinal profiling of glioma informs therapy development13 Feb 202600:19:20

Dr. Dave Rogawski interviews Dr. David Solomon on his research that sheds light on how key genomic alterations in high-grade glioma evolve over time and how these insights might inform therapeutic development.

A transcriptomic atlas of CNS tumors11 Jul 202500:35:22

Dr. Evan Noch interviews Dr. Akshitkumar Mistry about his and his team's recent manuscript entitled "A clinically annotated transcriptomic atlas of nervous system tumors", published online in Neuro-Oncology in May 2025

Link to the paper: https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noaf130/8151442

Loss of H3K27me3 in the Tübingen meningioma cohort21 May 202100:18:07

Dr. Maya Graham interviews Drs. Ghazaleh Tabatabai and Felix Behling about their paper entitled "H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort" published online in Neuro-Oncology in December 2020.

A prospective phase II randomized trial of proton radiotherapy vs intensity modulated radiotherapy for patients with newly diagnosed GBM07 May 202100:13:31

Dr. Jasmin Jo interviews Dr. Caroline Chung about her paper: "A prospective phase II randomized trial of proton radiotherapy vs intensity modulated radiotherapy for patients with newly diagnosed GBM" published online in Neuro-Oncology in Feb 2021.

Brain radiotherapy and decline in fine motor skills09 Apr 202100:18:04

Dr. Iyad Alnahhas interviews Dr. Jona Hattangadi-Gluth and Ms. Mia Salans about their recently published manuscript entitled: "Longitudinal change in fine motor skills after brain radiotherapy and in vivo imaging biomarkers associated with decline" published online in February 2021 in Neuro-Oncology.

A serum based DNA methylation assay to detect gliomas26 Mar 202100:33:05

Dr. Iyad Alnahhas interviews Dr. Houton Noushmehr about his recent paper "A serum-based DNA methylation assay provides accurate detection of glioma", published online in Feb 2021 in Neuro-Oncology

PTEN deficiency and proteosome addiction in glioblastoma12 Mar 202100:23:09

Dr. Evan Noch interviews Drs. Frank Furnari and Jorge Benitez about their recent paper: "PTEN deficiency leads to proteosome addiction, a novel vulnerability in glioblastoma" published online in Neuro-Oncology in January, 2021.

Cold-Inducible RNA-Binding Protein expression and recurrence of brain metastases26 Feb 202100:11:11

Dr. Alireza Mansouri interviews Dr. Matthew Dankner about his recent paper "Invasive growth associated with Cold-Inducible RNA-Binding Protein expression drives recurrence of surgically resected brain metastases" published online in Neuro-Oncology in January, 2021.

The incidence of brain metastases among patients with metastatic breast cancer12 Feb 202100:23:57

Dr. Iyad Alnahhas interviews Dr. Katarzyna Jerzak about her recent paper "The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis", published online in Neuro-Oncology in December, 2020. 

Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-201729 Jan 202100:17:14

Dr. Evan Noch interviews Dr. Jill Barnholtz-Sloan about her recent paper "Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-2017" published online in Neuro-Oncology in December 2020.

A large longitudinal study of patients with Neurofibromatosis Type 2.15 Jan 202100:20:42

Dr. Iyad Alnahhas interviews Dr. Gareth Evans about his recent paper in Neuro-Oncology entitled: "Disease course of Neurofibromatosis Type 2; a 30-year follow-up study of 353 patients seen at a single institution

Vorinostat and bevacizumab for recurrent glioblastoma01 Jan 202100:32:52

Dr. Iyad Alnahhas interviews Drs. Vinay Puduvalli and Ying Yuan about their paper "A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma" published in Neuro-Oncology in March 2020

Gut microbiome in primary CNS lymphoma27 Jun 202500:15:04
Dr. Iyad Alnahhas interviews Drs. Isaias Hernandez-Verdin and Agusti Alentorn about their recent manuscript entitled: "Gut microbiome modulates the outcome in primary central nervous system lymphoma patients undergoing chemotherapy: An ancillary study from the BLOCAGE trial", published online in Neuro-Oncology in March 2025   Link: https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noaf059/8058778
A subset of pediatric thalamic gliomas18 Dec 202000:20:50

Dr. Iyad Alnahhas talks with Dr. Felix Sahm about his recently published article in Neuro-Oncology entitled: "A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR," published online on November 1, 2020.

Supratotal resection of lower-grade gliomas04 Dec 202000:19:25

Dr. Alireza Mansouri talks with Dr. Lorenzo Bello about his recently published article in Neuro-Oncology entitled: "Association of Supratotal Resection with Progression-Free Survival, Malignant Transformation, and Overall Survival in Lower-Grade Gliomas," published online on October 13, 2020.

Friends of SNO20 Nov 202000:25:48

In this premiere episode, we will bring you some brief conversations with the current leaders of: The Society for Neuro-Oncology, the European Association of Neuro-Oncology, The Asian Society for Neuro-Oncology and the World Federation of Neuro-Oncology Societies

 

Announcing Neuro-Oncology: The Podcast19 Nov 202000:00:39

Dr. Iyad Alnahhas, producer, introduces the new podcast.

Germline analysis of diffuse midline glioma08 Jun 202500:29:55

Dr. Evan Noch interviews Dr. Marion Mateos about her and her team's recent manuscript entitled: "Germline analysis of an international cohort of pediatric diffuse midline glioma patients", published online in Neuro-Oncology in March 2025.

The proteomic landscape of diffuse midline glioma17 May 202500:16:55

Dr. Iyad Alnahhas interviews Drs. Cynthia Hawkins and Arun Vadivel about their recent manuscript entitled: "The proteomic landscape of diffuse midline glioma highlights the therapeutic potential of non-histone protein methyltransferases", published online in Neuro-Oncology in February 2025.

 

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Radio-Pathomic maps and MR perfusion18 Apr 202500:20:25

Dr. Iyad Alnahhas interviews Dr. Peter LaViolette about his and his team's recent manuscript entitled: "Multi-Site Retrospective Analysis of Diffusion and Perfusion MRI Correlates to Glioma Characteristics Derived from Radio-Pathomic Maps", published online in Neuro-Oncology in February 2025.

CSF proteomics in glioma21 Mar 202500:44:15
Description: Dr. Evan Noch interviews Drs. Cecile Riviere-Cazaux and Terry Burns about their recent manuscript entitled: "A field resource for the glioma cerebrospinal fluid proteome: impacts of resection and location on biomarker discovery", published online in Neuro-Oncology in December 2024.   Link: https://doi.org/10.1093/neuonc/noae277  
Vorasidenib in IDH mutant glioma08 Mar 202500:42:44
Description: Dr. Ankush Bhatia interviews Drs. Macarena de la Fuente and Mehdi Touat about their recent manuscript entitled: "The role of vorasidenib in the treatment of isocitrate dehydrogenase-mutant glioma" published online in Neuro-Oncology in December 2024.   Link: https://doi.org/10.1093/neuonc/noae259
KL-50 in post TMZ MMR-deficient GBM22 Feb 202500:21:33

Dr. Iyad Alnahhas interviews Dr. Craig Horbinski about his and his team's recent manuscript entitled "The novel DNA cross-linking agent KL-50 is active against patient-derived models of new and recurrent post-temozolomide mismatch repair-deficient glioblastoma", published online in Neuro-Oncology in December 2024.

Measurable disease per FET-PET vs MRI in GBM08 Feb 202500:14:06

Dr. Iyad Alnahhas interviews Dr. Nathalie Albert about her and her team's recent manuscript entitled: "Measurable disease as baseline criterion for response in glioblastoma: A comparison of PET-based (PET RANO 1.0) and MRI-based (RANO) assessments", published online in Neuro-Oncology in January 2025.

Pre-radiation chemotherapy in GBM20 Jan 202500:13:42

Dr. Iyad Alnahhas interviews Dr. Danielle Bazer about her and her team's recently published manuscript, entitled: Using a Pre-Radiation Window to Identify Potentially Active Cytotoxic Agents in Adults with Newly Diagnosed Glioblastoma", published online in Neuro-Oncology in November 2024.

Neuro-oncology Nugget: Microbubble-enhanced transcranial focused ultrasound with temozolomide for patients with high-grade glioma09 Feb 202600:03:00

Dr. Haseeb Mehmood discusses the use of microbubble-enhanced transcranial focused ultrasound combined with standard temozolomide in high-grade glioma.

cIMPACT-NOW Update 8: grading of meningiomas13 Dec 202400:43:16
Dr. Rachna Malani interviews Drs. Felix Sahm and Arie Perry about their recent manuscript entitled: "cIMPACT-NOW Update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas", published online in Neuro-Oncology in August 2024   Read More
Residual tumor volume and survival after CCNU/TMZ in GBM24 Nov 202400:13:18

Dr. Iyad Alnahhas interviews Drs. Thomas Zeyen and Johannes Weller about their recent manuscript entitled: "Quantitative assessment of residual tumor is a strong and independent predictor of survival in methylated glioblastoma following radiochemotherapy with CCNU/TMZ", published online in Neuro-Oncology in October 2024.

Alterations in RNA splicing between meningioma DNA methylation groups08 Nov 202400:33:46

Dr. Evan Noch interviews Drs. Nathan Leclair, David Raleigh and Olga Anczukow about their recent manuscript entitled: "RNA splicing as a biomarker and phenotypic driver of meningioma DNA methylation groups", published online in Neuro-Oncology in August 2024.

 

The immune landscape of IDH mutant and IDHwt glioma25 Oct 202400:33:27

Dr. Evan Noch interviews Drs. Pravesh Gupta and Krishna Bhat about their recent manuscript entitled "Immune landscape of isocitrate dehydrogenase-stratified primary and recurrent human gliomas", published online in Neuro-Oncology in August 2024

Read Paper

Equity-driven applications of AI in neuro-oncology09 Oct 202400:22:34

Dr. Iyad Alnahhas interviews Dr. Mulki Mehari about her and her team's recent manuscript entitled: "Enhancing neuro-oncology care through equity-driven applications of artificial intelligence", published online in Neuro-Oncology in August 2024.

IDH mutant glioma across age groups20 Sep 202400:34:34

Dr. Maya Graham interviews Drs. Mary Jane Lim-Fat and Kee Kiat Yeo about their recent manuscript entitled "A comparative analysis of IDH-mutant glioma in pediatric, young adult, and older adult patients", published online in Neuro-Oncology in July 2024.

Link: https://doi.org/10.1093/neuonc/noae142

Contemporary molecular prognostic signatures in glioma30 Aug 202400:20:00

Dr. Iyad Alnahhas interviews Dr. Linda Bi, Hia Ghosh and Ruchit Patel about their recent manuscript entitled: "Contemporary Prognostic Signatures and Refined Risk Stratification of Gliomas: An Analysis of 4400 Tumors", published online in Neuro-Oncology in August 2024.

More Information:
https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noae164/7737688

FDG PET in PCNSL09 Aug 202400:09:36
Dr. Iyad Alnahhas interviews Drs. Minyoung Oh and Hyungwoo Cho about their recent manuscript entitled: "Enhancing Prognostication and Treatment Response Evaluation in Primary CNS Lymphoma with 18F-FDG PET/CT", published online in Neuro-Oncology in August 2024.   Link to manuscript
TMZ and MGMT in elderly GBM patients12 Jul 202400:17:46

Dr. Jasmin Jo interviews Dr. Monika Hegi about her and her team's recent manuscript entitled: "No benefit from TMZ treatment in GB with truly unmethylated MGMT promoter: Reanalysis of the CE.6 and the pooled Nordic/NOA-08 trials in elderly GB patients", published online in Neuro-Oncology in (I will fill in through Libsyn)

IDH mutant glioma and IDH inhibitors05 Jul 202400:24:11

Dr. Maya Graham interviews Dr. Martin van den Bent about his and his team's recent review article entitled "The biological significance of age, enhancement, extent of resection and tumor grade in IDH mutant gliomas: how should they inform treatment decision in the era of IDH inhibitors? Invited review", published online in Neuro-Oncology in

SNObound: Career Advice from Neuro-oncologist, Dr. Lisa DeAngelis06 Feb 202600:34:24

Dr. Evan Noch interviews Dr. Lisa DeAngelis about her career in neuro-oncology, role as Chair of Neurology and Physician-in-Chief at Memorial Sloan Kettering Cancer Center, and advice for trainees entering the field.

Leptomeningeal disease, a SNO and ASCO review28 Jun 202400:38:03

 Dr. John Fortunato interviews Dr. Adrienne Boirre about her and her team's recent manuscript entitled "Leptomeningeal metastases from solid tumors: A SNO and ASCO consensus review on clinical management and future directions", published online in Neuro-Oncology on 

Cancer stems cell in GBM21 Jun 202400:31:27

Dr. Iyad Alnahhas interviews Drs. Justin Lathia and Marco Gallo about their recent manuscript entitled "Cancer stem cell hypothesis 2.0 in glioblastoma: where are we now and where are we going?", published online in Neuro-Oncology in May 2024.

Drug delivery across the blood-brain barrier13 Jun 202400:23:19

Dr. Ankush Bhatia interviews Dr. Keaton Piper about his and his team's manuscript, entitled "Consensus Review on Strategies to Improve Delivery Across the BBB Including Focused Ultrasound", published online in Neuro-Oncology in May 2024

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Gliomatosis cerebri in children24 May 202400:42:45

Dr. Evan Noch interviews Dr. Gunther Nussbaumer about his recent paper entitled: "Gliomatosis cerebri in children: a poor prognostic phenotype of diffuse gliomas with a distinct molecular profile" published online in Neuro-Oncology in May 2024.

Immunotherapy drives mesenchymal shift in GBM17 May 202400:24:18

Dr. Maya Graham interviews Drs. Josephine Hendriksen and Joachim Weischenfeldt about their recent manuscript, "Immunotherapy drives mesenchymal tumour cell state shift and TME immune response in glioblastoma patients," published online in Neuro-Oncology in May 2024.

Long-term outcomes of pediatric patients with optic pathway glioma04 May 202400:15:11

Dr. Iyad Alnahhas interviews Drs. Alice Morin, Samuel Abbou and Brice Fresneau about their recent manuscript entitled "Very long-term outcomes of pediatric patients treated for optic pathway gliomas: a longitudinal cohort study" published online in Neuro-Oncology in March 2024.

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NF1 mutation and neuronal hyperexcitability12 Apr 202400:22:56
Postoperative cerebellar mutism05 Apr 202400:32:20

Dr. Rachna Malani interviews Dr. Hrishikesh Suresh about his and his team's recent manuscript entitled "Postoperative cerebellar mutism syndrome is an acquired Autism-like network disturbance", published online in Neuro-Oncology in December 2023.

Read the paper

Cell cycle checkpoints and alkylating agents22 Mar 202400:18:20

Dr. Evan Noch interviews Dr. Chunzhang Yang about his and his team's recent manuscript entitled "Abrogation of the G2/M checkpoint as a chemo sensitization approach for alkylating agents" published online in Neuro-Oncology in December 2023

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Liquid biopsy in CNS lymphoma15 Mar 202400:21:29

Dr. Iyad Alnahhas interviews Dr. Ricardo Soffietti about the recent RANO review entitled "Liquid biopsy for improving diagnosis and monitoring of CNS lymphomas: a RANO review" published online in Neuro-Oncology in March 2024.

Read the paper

Author Interview: Pamiparib and TMZ in recurrent IDHmt gliomas02 Feb 202600:23:18

Dr. Iyad Alnahhas interviews Drs. David Schiff and Ranjit Bindra about their recent manuscript entitled "Phase I/II and Window-of-Opportunity Study of Pamiparib and Metronomic Temozolomide for Recurrent IDH Mutant Gliomas", published online in Neuro-Oncology in October 2025.

Immunotherapy for glioblastoma, lessons learned08 Mar 202400:29:55

Dr. John Fortunato interviews Dr. Antonio Chiocca about his and his team's recent manuscript entitled "Lessons learned from phase 3 trials of immunotherapy for glioblastoma: time for longitudinal sampling?" published online in Neuro-Oncology in February 2024.

Get paper.

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