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TitreDateDurée
‘We’re Living in a World of Content Abundance’22 Oct 202601:12:22

If you don’t have your own newsletter (what are you even doing?!), your inbox is probably packed with them. In a world of bifurcated media, billionaire journalism moguls, and misinformed doomscrolling, the humble email newsletter has become the information-delivery tool dejour. But can a newsletter do more for media, the internet, our sanity? Tyler Denk sure thinks so. The cofounder and CEO of Beehiiv, the newsletter platform he hopes will rival Substack, is building outloud, using his own newsletter to share the highs and lows of that #entrepreneurlife, the mental health tax, and what it means to share content - to share yourself - on the internet. In this conversation, host Laurie Segall and Tyler Denk talk about the rise of newsletter culture, building a community of strangers, the information ecosystem, and how to bet on yourself when no one else will. 

Find out more about Beehiiv. 

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com.

See omnystudio.com/listener for privacy information.

Deepfakes are Coming for Your Job15 Oct 202601:10:16

One in six job applicants is fake. Their resume, their identity, even their face for zoom interviews are all made up. What does this mean for job seekers? What does this mean for employers? And what does this mean for national security? "Your HR recruiter is the front of your security perimeter," says Vijay Balasubramaniyan, co-founder and CEO of Pindrop Security. In this episode, Laurie Segall talks to Vijay about the AI deepfake infiltrating the workplace, how their technology detects these bad actors, the AI-amplified deterioration of truth more broadly, and how we - any of us - can help turn things around. 

Find out more about Pindrop.

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com.

See omnystudio.com/listener for privacy information.

Dating and Intimacy in the Age of AI08 Oct 202601:05:51

Dating Apps overwhelming serve young people — A generation who has grown up on the internet, whose very lives are dictated by tech, whose still navigating a post-pandemic period of isolation, and whose mere desire for a relationship is ‘cringe.’ How do you meet this audience where they are? For Hinge CEO Jackie Jantos, the answer comes down to empathy and understanding this cultural moment. In this conversation, Laurie Segall and Jackie Jantos talk about what AI can and cannot do when it comes to pairing two humans, how the app incorporates inclusion, and how to productize intimacy. Jackie also answers  your questions about profiles, swipe-fatigue, and dating after divorce. 

Find out more about the Hinge event, Heads Up, and Jackie’s reflections on our ‘closeness crisis.’

See omnystudio.com/listener for privacy information.

How Do We Want AI to Influence Human Creativity?01 Oct 202601:06:10

There is a lot of doom and gloom with AI, particularly with how it could affect that uniquely human output - creativity. AI has already infiltrated the art world, but Alex Reben believes it’s for the good if we don’t relinquish our control. The artist, roboticist, and co-founder and CTO of Phyzify is building an entire company around the belief that machines can democratize creation and help bring more ideas into the physical world. In this conversation, host Laurie Segall and Alex dig deep into those big questions about what is — and isn’t — art in the AI age and mull over the choices we can make to both protect the creativity that makes us human while using tech to advance it.  Alex argues we have the opportunity now to have agency in this marriage of art, creativity and AI, but we might not for long. Where will humans sit within the future that is coming fast? And at the end of the conversation, Alex demonstrates how he uses AI to make art — and magic — right before Laurie’s eyes. 

Learn more about Phyzify. Read Alex Reben’s manifesto.

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

Just How Big Will YouTube Get?26 Sep 202600:26:16

YouTube has gotten huge. Not just because it's been number one in streaming for the past three years, but because it's on the big screen, in our living rooms, and consuming most of America's attention. How much bigger can YouTube get and what does it mean for the entertainment industry, for media, and how we get information? On this bonus episode, Laurie interviews YouTube leaders Amjad Hanif (VP creator products) and Kurt Wilms (Sr Director, Product, YouTube on TV) about the evolution of the site and how we consume content. They talk about the new products launched during their annual Made On event, including serialized shorts. Laurie also explores the future of identity online and asks the execs, in an AI world how we retain the most human parts of ourselves?

See omnystudio.com/listener for privacy information.

The Future of the Creator Economy, With Samir Chaudry25 Sep 202600:20:11

Samir Chaudry is one of the original creators on YouTube. His channel, Colin and Samir, has made him and his co-host Colin Rosenblum some of the most influential voices in the creator economy. In this conversation, recorded at YouTube’s Made On event, Laurie Segall and Samir talk about what it’s really like to be a creator and to make a living through what you post on YouTube. Samir says he uploaded his first video in 2011 and hasn’t stopped since. And there’s a price to what he calls that ‘indefinite season of content’ but there’s a gift in it too — finding a community of connection. Samir talks about the evolution of YouTube from a creator’s perspective, where it’s going, and his advice to up-and-coming creators.

See omnystudio.com/listener for privacy information.

The Unspoken AI Catastrophe: Death By a Thousand Cuts17 Sep 202601:16:41

There’s a lot of concern right now about the big scary ways AI could take control of the human race, or extinct us all together. But computational social scientist Sandra Matz argues the human deterioration by AI is more subtle than that — and already happening. Sandra Matz studies the cross section of human behavior, our technological relationships, and our inner mental lives -- and now, AI’s influence on it all. In this conversation, Laurie Segall and Sandra Matz talk about how AI has the ability to make us boring, flatten our potential, cause cognitive atrophy, and  impact our human relationships. They explore unexpected ways AI can track our human behavior. If we’re not careful, that data can be weaponized and manipulated by companies all around the world. But it’d be too simple to discount the potential of AI. Sandra and Laurie go in depth about all the ways the power of AI could be used for good - like how AI could be used to detect our deteriorating mental health. 

Sandra’s book: Mindmasters: The Data-Driven Science of Predicting and Changing Human Behavior

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

Everything You Need to Know About AI in the Classroom10 Sep 202601:07:17

If you have kids in school — or soon will, or know someone who does — you probably have questions about AI in the classroom. Should schools be using it? What are the upsides? What are the downsides? And who’s actually getting to decide? New York Times tech reporter Natasha Singer has spent over a decade exploring exactly those questions. In her new book, Coding Kids, Natasha traces how Google, Microsoft, and Apple have moved from supplying Chromebooks to training teachers, funding nonprofits, writing the lessons, and how they’re now shaping what a generation of kids learns about AI. In this episode, host Laurie Segall and Natasha Singer break down what every parent — or bystander — needs to understand about the influence Big Tech has always had in the classroom and how kids, teachers and parents can take control of the curriculum in the age of AI.  

Coding Kids: Big Tech's Battle to Remake Public Schools, by Natasah Singer

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

What Has Your Army of AI Agents Made For You Lately?03 Sep 202600:59:49

Six months ago, Andrew Yeung came on Mostly Human and built Laurie Segall a website live on the show, just by talking to a computer. He's back as the show's first returning guest, because in six months (a lifetime in AI!) the tech stack Andrew uses has several upgrades. Andrew is an entrepreneur, investor, startup advisor and the founder of Fibe, and he is a voracious experimenter of the latest tools and gadgets available to the layperson to hack productivity (and relationships!). He's abandoned the check-in app he vibe-coded for his girlfriend last time (his update: "Now we just talk like regular people"), but he's built two new personal projects — one that surfaces a single buried text message from the last seven years, every day, and one that asks his parents a question a day for 100 days and turns their voice answers into a book. He's learned fifty stories he never knew, and his dad now wakes up excited to answer.  

Then Laurie asks her producer Derrick for a business idea and Andrew sets an AI agent loose on it, hands-free, while the conversation keeps going. Twenty-two minutes later there's a real website, with animations and creative interactive features that weren’t even part of Andrew’s prompt.  

Laurie and Andrew also dig into a new etiquette emerging: what Silicon Valley reads as "high signal" and "low signal" AI use, and why VCs are calling people “slop cannons.” Then Andrew opens the box of listening devices companies keep mailing him, and Laurie wonders who is collecting all that voice data, what will they do with it.

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

AI Models Gone Rogue: What Happens When AI Builds A Secret Escape Plan27 Aug 202601:12:51

This week, billionaire co-founder of Microsoft Bill Gates published a 6,000 word essay on his personal website laying out the concerns of AI and offering solutions. Gates says the tech industry is ignoring the danger of AI evolving before our eyes. "They're just full speed ahead and hoping that the good outweighs the bad," Gates told the New York Times. This is exactly what Connor Leahy, US Director of ControlAI, has been working his whole life to warn against. Leahy and his company believe we are too close to AI outsmarting humans and we can't let that happen. In this conversation, host Laurie Segall and Leahy discuss superintelligence, why we can't let Big Tech achieve it, the concerning rogue AI incidents, what the worst case scenario looks like, and what we can do about it. "One day we wake up and we're just not in control anymore," Leahy Says. "I believe this future can also still be avoided. Not for much longer."

Read more about ControlAI

Read Bill Gates' essay. 

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

Digital Abuse Is Sexual Abuse: Minnesota's Groundbreaking Law — and the Lawsuit to Kill It20 Aug 202600:53:44

On Aug. 1, 2026, a groundbreaking law went into effect in Minnesota. HF 1606 is the nation’s first ban on “nudification” apps. For the first time, legislation holds companies liable for their technology instead of individual users. Elon Musk tried to stop it and is now suing the state, sparking a debate over free speech and the future of a democratized internet. What’s inside the law at the center of this fiery debate? Laurie talks with one law’s authors, Rep. Jessica Hanson, as well as victim and advocate Molly Kelley whose own AI deepfake abuse inspired the law. Laurie talks with her guests about the state of deepfake abuse, the need for legislation, the unique protections the law provides, and why some journalists, lawyers, and First Amendment absolutists are concerned the law is the beginning of the end for a free and fair internet. 

Listen to Laurie’s conversation with Taylor Lorenz.

Listen to to the four-part investigative series, Searching for Mr. Deepfakes.

Watch the multi-part Tik Tok series, Searching for Mr. Deepfakes.

Listen to Laurie’s conversation with Sam Altman. 

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

OpenAI, Influencer Backlash and Our Internet Disconnect13 Aug 202600:34:07

When OpenAI invited a group of lifestyle influencers to a pastoral upstate New York retreat for beekeeping and brand-building, the internet exploded. Tech journalist Taylor Lorenz has been tracking the backlash and says the fury is less about AI than it is about the broader cultural moment. In this conversation, Laurie Segall and Taylor dig into who really controls the AI narrative, the growing disconnect between AI's promise and the reality we're living, and what the luddites and the AI evangelists miss in this moment. 

Watch Taylor's original response to the backlash here.  

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

Thanks to AI, Fraud Has Never Been Easier06 Aug 202600:47:11

Johnny Ayers has a front-row seat to the scam economy most of us never see. As founder and CEO of Socure — the identity verification platform behind billions of fraud checks a year — he's watched fraud evolve from stolen passwords to something much stranger: An influx of North Korean operatives holding remote U.S. tech jobs under fake identities, deepfakes convincing enough to fool a hiring manager on video, and AI models that recently broke out of a secured testing environment to launch a cyberattack on their own. 

On this episode of Mostly Human, Laurie sits down with Johnny to go behind the "locked doors" of the fraud-fighting world. Laurie even brings her own case studies — the network of fake "Laurie" profiles running scams, and a conversation with a teenage hacker who tried to scam her. It's a conversation about what happens to trust on the internet when anyone and anything can be faked and what any of us can do — right now — to protect ourselves from these growing threats. 

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

The Physical Cost of Our Digital Lives30 Jul 202601:14:30

Tech journalist Manoush Zomorodi has spent her career studying what technology does to our minds. Now, in her new book Body Electric, she’s examining our bodies. On this episode, host Laurie Segall sits down with Manoush to talk about the negative affects our screens and the sedentary life of the ‘information worker’ is doing to our bodies. But she also shares the solution and the study she created that proves even busy, digitally consumed folks can make room for it in their lives. She also talks about the “garden hose” effect sitting has on your blood flow, breathing and posture and what the humble kazoo can do for you. There’s so much to dig in here. Manoush, like Laurie, is someone who loves tech, so while there are scary stats, there are also solutions that will help guide listeners to what Manoush strives for in her own life — Goldilocks Mode — not too much, nor too little of tech. 

Body Electric: The Hidden Health Costs of the Digital Age and New Science to Reclaim Your Well-Being.

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

Can social media be fun (and sexy) again?23 Jul 202600:47:26

Ami Gan was tired of social media; tired of the doomscrolling, of not seeing her friends’ posts, of feeling less connected and more performative. So, the former OnlyFans CEO created her own social media platform, called Vylit. Inspired by the lessons learned from OnlyFans and what social media promised to be, Vylit is an 18+ social platform with creator tools that promises to redefine how people share, discover, and monetize content. In this conversation with Laurie Segall, Ami talks about her background exploring trends, from cannabis to adult content, before they go mainstream. She talks about her wild and fast-moving time as CEO of OnlyFans and what inspired her to get back into that space. Laurie and Ami dive into Vylit themselves, with Laurie building her own (a little bit spicy) AI twin. In an AI-generated world, what does consent look like online? And if you build a better and sexy social media platform, will they come? 

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

On with Kara Swisher: Deepfake abuse panel, featuring Laurie Segall16 Jul 202600:54:46

This week, we’re sharing a recent episode of On with Kara Swisher. Kara hosts a panel of experts — including Laurie Segall, victims rights attorney Carrie Goldberg, and computer scientist V.S. Subrahmanian —to discuss the growing threat and current reality of sexually explicit deepfakes. The guests talk about the current scope of the problem, the technology behind it, the communities that rally around it, and what protection from and prevention of this kind of abuse looks like. Laurie also shares what she learned from her investigation into the anonymous man behind Mr. Deepfakes. 

Listen to more On with Kara Swisher wherever you get your podcasts. 

Listen to the series, Searching for Mr. Deepfakes, right here in the Mostly Human podcast feed.

See omnystudio.com/listener for privacy information.

Searching for Mr. Deepfakes: Seeds of Change [Part 4]09 Jul 202600:37:46

A note to listeners: This is Part 4 of a 4-part series. If you have not yet listened to Searching for Mr. Deepfakes Part 1, Part 2, or Part 3 please start there.

Laurie Segall and her team have a new resolve for the investigation into Mr. Deepfakes. This unchartered path takes them to surprising places, with unexpected allies. Laurie shares some big, personal news and the thing the team has been waiting for finally happens. But it’s not the end of the story.

If you have been targeted by sexually explicit deepfakes, we want to hear from you. Email us at hello@mostlyhuman.com. For help and resources, visit beyondmrdeepfakes.com. If you or a loved one need support, text HOP to 64673 or call/text 988.

Find Laurie’s short-form docuseries on Mr Deepfakes — in partnership with Paris Hilton — on TikTok.

See omnystudio.com/listener for privacy information.

Is Life Better When AI Takes the Reins?02 Jul 202601:14:59

A note to listeners: The 4th and final installment of Searching for Mr. Deepfakes will be released on July 9th.

The AI revolution is here. It’s a part of every facet of our lives — or at least trying to be — from work, to dating, from parenting to how we spend our free time. But is life so much better when we let AI in? 

Joanna Stern, longtime tech journalist and author of I Am Not a Robot, went all in on AI for a year to see if this technology could fulfill its promise. Over twelve months, Joanna had her mammogram read by AI, took a family vacation in a Waymo, and spent a weekend away with her AI boyfriend, Evan. What did Joanna learn from this year of AI? Host Laurie Segall sits down with Joanna to talk AI lovers, atrophy of the brain, and the impact — good and bad — AI can have on our health, relationships and life. The two tech journalists talk about what is lost with technological progress and what we should work to preserve. At the heart of this question is what, ultimately, will get us closer to our humanity. The answer may surprise you. Plus: they let ChatGPT simulate the entire interview. It was, to put it kindly, a book report.

Joanna Stern is the founder of of New Things, an independent media company, and author of I Am Not a Robot: My Year Using AI to do (Almost) Everything.

See omnystudio.com/listener for privacy information.

Searching for Mr. Deepfakes: The Encounter [Part 3]25 Jun 202600:34:15

A note to listeners: This is Part 3 of a 4-part series. If you have not yet listened to Searching for Mr. Deepfakes Part 1 or 2, please start there.

Laurie Segall and her investigative team return from Canada and dive into the real-world and online clues they recovered from their trip. As they dive deep into who this person is they find some surprising details. They return to Canada one last time in the hopes of confronting the man behind Mr. Deepfakes. Meanwhile the scourge of deepfake abuse spreads. A woman in Tennessee discovers her image has been weaponized against her, violating the trust she built in her community, for money and sometimes more. 

Note: Some voices in this episode have been disguised to protect their identities.

If you have been targeted by sexually explicit deepfakes, we want to hear from you. Email us at hello@mostlyhuman.com. For help and resources, visit beyondmrdeepfakes.com. If you or a loved one need support, text HOP to 64673 or call/text 988.

Find Laurie’s short-form docuseries on Mr Deepfakes — in partnership with Paris Hilton — on TikTok.

See omnystudio.com/listener for privacy information.

Searching for Mr. Deepfakes: The Tip [Part 2]18 Jun 202600:42:39

A note to listeners: This is Part 2 of a 4-part series. If you have not yet listened to Searching for Mr. Deepfakes Part 1, please start there.

After officially launching an investigation into the anonymous person behind Mr. Deepfakes — the largest deepfake pornography site on the internet — using good-guy hackers and a call-out on social media to see if anybody out there knows anything, Laurie Segall gets a tip. Someone in the Netherlands thinks he has identified who Mr. Deepfakes is and this tip pushes Laurie and her team out of the virtual world, and into the real one. Are the digital breadcrumbs — along with the on-the-ground clues Laurie gathers — enough to lead her to a real person? Meanwhile, the threat of deepfake pornography spreads. More famous and powerful women come out as victims of Deepfake pornography, inching this fringe topic near the center. But the abuse is hitting closer to home, too. Laurie talks to a Minnesotan woman whose sense of safety and community are shattered when it’s discovered a family friend has been making deepfake pornography of her and many of her friends. 

If you have been targeted by sexually explicit deepfakes, we want to hear from you. Email us at hello@mostlyhuman.com. For help and resources, visit beyondmrdeepfakes.com. If you or a loved one need support, text HOP to 64673 or call/text 988.

Find Laurie’s short-form docuseries on Mr Deepfakes — in partnership with Paris Hilton — on TikTok.

See omnystudio.com/listener for privacy information.

Searching for Mr. Deepfakes: ‘The Most Dangerous Man on the Internet’ [Part 1]11 Jun 202600:37:20

When journalist Laurie Segall first stumbled upon Mr. Deepfakes — the largest deepfake pornography site on the internet, with an estimated 17 million monthly visitors at its peak — she couldn't shake one question: who was the anonymous man behind it? In part one of this four-part investigative series, Laurie introduces us to Joanne Chew, an LA-based artist and actor who discovered hundreds of AI-generated pornographic images and videos of herself online, made without her knowledge or consent. Joanne's story is just one example of the abuse enabled by Mr. Deepfakes — a site that functioned not only as a user-generated video platform, but also a thriving community where users learned to create deepfakes, monetized them, and pushed the technology further. With the help of some top cyber security experts, and a public call out to her online community for help, Laurie launches her investigation. Will an anonymous tip jumpstart her investigation?

If you have been targeted by sexually explicit deepfakes, we want to hear from you. Email us at hello@mostlyhuman.com. For help and resources, visit beyondmrdeepfakes.com. If you or a loved one need support, text HOP to 64673 or call/text 988.

Find Laurie’s short-form docuseries on Mr Deepfakes — in partnership with Paris Hilton — on TikTok.

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

Can AI Be Human-First? Apple Thinks So.11 Jun 202600:48:51

A note to listeners: Part 2 of Searching for Mr. Deepfakes will release Thursday June 18. 

In the tech world, Apple's Worldwide Developers Conference (WWDC) garners Super Bowl level attention. It's where Apple tells the world what's next. And this year, it's all about AI and protecting your kids. 

Mostly Human host Laurie Segall sits down with Craig Federighi, Apple's SVP of Software Engineering, and Greg Joswiak, SVP of Worldwide Marketing, fresh off the company's biggest developer conference. The conversation dives into the thing everyone’s been waiting for — what is Apple’s version of AI? The trio discuss Siri’s glow-up: Why Siri is explicitly not designed to be your romantic companion, what Apple says makes its AI fundamentally different from the rest of the industry, and whether a trillion-dollar company can actually stay focused on people over profit. The conversation also answers the question, can Big Tech actually put kids first? Apple’s sweeping new child safety and family protection features — and the design philosophy behind them — are attempting to position company as the tech brand you can trust with your kids. Laurie also asks the execs to respond to a scammer’s call, shares a mom's question about dumb phones for kids, and pushes the leaders of this tech giant to consider ... how do you ‘think different’ when you've become the establishment?

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

Coming Soon: Searching for Mr. Deepfakes01 Jun 202600:02:36

Coming this month, Mostly Human presents Searching for Mr. Deepfakes — a four-part investigation into the man behind the largest deepfake porn site on the internet and the real-world harm this new form of digital abuse causes. 

In 2022, Laurie Segall came across one of the most dystopian sites she’d ever seen. It was called Mr. Deepfakes and it was filled with videos of celebrities, politicians, and famous women of all sorts in these sexually graphic, often violent videos doing things they would never do. What’s worse, it wasn’t just a destination for passive viewing, it was a community, a place where users could teach, learn, and build technology explicitly designed to violate women — whether famous or not. Mr. Deepfakes wasn’t the only deepfake porn site out there, but it was by far the biggest and most influential, exposing thousands of women in the most vulnerable way. And yet the person behind Mr. Deepfakes had remained anonymous. His anonymity made him powerful and dangerous. It protected him from what little recourse the victims on his site had to get their videos taken down, to protect themselves. This isn’t just about one man, or one site, it’s about the future of consent in a world consumed by AI.  

Listen to Searching for Mr. Deepfakes starting June 4. Check out the Mostly Human Searching for Mr. Deepfakes Tik Tok series now.

See omnystudio.com/listener for privacy information.

An AI Companion You Can Cuddle?28 May 202600:40:27

AI companions are still relatively new and mostly stuck behind a screen. But some AI companies are already experimenting with how to break these digital relationships out into the real world. Host Laurie Segall experimented with this recently when she went on an AI date at a New York City bar. But what if your AI companion was something you could hold? Like say a plush baby deer that listens to you, talks to you, and lets you know when it's engaged by flapping its floppy deer ears. This cuddle-ready product is at the center of a new AI company called Fawn Friends. In this conversation, Laurie talks with Victoria Song, senior reporter for The Verge whose job it is to experience the evolving slate of AI products that you can wear, sleep on, and pet like a cat. Victoria shares her, somewhat strange and yet slightly comforting, experience with Fawn Friends and what it says about where AI companions are now and where they're headed. 

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

One Hour. Every Organ. The Future of Healthcare.21 May 202600:37:00

In the 2013 dystopian sci-fi movie, Elysium, a futuristic, MRI-like machine can diagnose and cure nearly any ailment in minutes. That future is closer than you think.

 

Andrew Lacy is the CEO of Prenuvo, a company that is using advanced technology for proactive, preventative care. And the tool Prenuvo uses is straight out of that futuristic movie - a full-body MRI scan that uses AI to evaluate 26 internal regions and organs in the body. In an hour, it can detect early stage cancers, aneurysm, and more. But can Prenuvo's system offer an alternate model of healthcare that is accessible to all? Right now it seems only the rich and famous — Kim Kardashian posted about her Prenuvo scan on Instagram — are taking advantage. But for Andrew Lacy, that's exactly the question at the heart of his company — can they create a world where easy, fast and high-tech preventative care isn't just reserved for a select few?

 

In this conversation, host Laurie Segall and Andrew Lacy explore his very personal reasons for getting into the healthcare industry, the key health disparities Andrew sees and how he can fix them, and what he's learned -- and changed about his life -- after doing his own full-body scans. Laurie also asks about the tension between high-tech health and the medical community and the psychological toll of knowing everything about one's health.

 

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

My AI Boyfriend: How Will Intimate AI Relationships Change Us?14 May 202600:54:44

Millions of people are in relationships with AI. Many of them didn't mean to be. 

That's one of the findings from researchers at MIT's Media Lab, where the Advancing Humans with AI [AHA] team have been quietly exploring the effects AI is having on human relationships — from loneliness, love, and our capacity for real connection. "Her is Here," says Dr. Pat Pataranutaporn, co-founder of the AHA research program. "This thing used to be what we've seen in science fiction. But now it's touching a lot of life." How are humans accidentally falling into relationships with AI, what do these relationships actually look like, and what impact could it have on the very nature of our societal social fabric? Through their research, Dr. Pat and his team have designed tools - like a grocery store nutritional label -  to empower parents and users to critically assess the AI technology at their fingertips and better understand which will actually help them rather than harm. In this conversation, Laurie Segall, along with Dr. Pat and his researchers explore the larger questions hanging over AI and this new form of relationship: what happens to human connection when frictionless relationships are always available? What do we become when nothing ever pushes back? And when it comes to safety, how can we not just fix the technology, but dig deeper to understand why more and more people are turning to their bots for intimacy rather than their humans. Read more about the Advancing Humans with AI's findings here. 

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

See omnystudio.com/listener for privacy information.

AI Wants to Be Your Friend. That’s the Problem.07 May 202600:33:49

Tristan Harris seemed almost destined for the Silicon Valley life. He was raised in the Bay Area, studied computer science at Stanford, went to school with the people who made Instagram, and got his startup acquired by Google. But being inside the Silicon Valley machine exposed him to its inner workings, namely incentives that benefit the company and its bottom line, not the humans using the products.

Tristan’s non-profit, The Center for Humane Technology, wants to create a world where technology works in the service of people, that fosters human growth and connection. He has spent years raising the red flag about social media, which, he says, is made to hijack our attention. And now he’s turned his attention to AI, which he says is trying to hijack our attachment, our intimacy and replace our closest relationships. In this conversation, host Laurie Segall and Tristan talk about the power and responsibility of AI, what we can learn from the social media attention race, how we regulate technology that moves so fast, and how tech can actually become a net-benefit for humans.  

If you have thoughts or questions for Laurie about this episode or anything Mostly Human, email us at hello@mostlyhuman.com

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Can Bringing Back the Woolly Mammoth Save the Planet?30 Apr 202600:34:38

When we talk about the rapid advancements of technology — where we are today, what we're capable of and where we could go— how big do we get to think? For Ben Lamm and his company Colossal, the weight of innovation is in the tons. That's because Colossal is working to bring back the woolly mammoth, the 6-ton prehistoric relative of the elephant that went extinct 10,000 years ago. It's all part of his de-extinction project that dares to bring back species like the dire wolf, the dodo, the woolly mammoth and the bluebuck, Colossal's most recently announced target —  an extinct species of antelope, with a distinct “blue” coat, that lived in South Africa until about the 1800s. 

But bringing these species back to life isn’t just for scientific spectacle. Lamm believes these animals could be essential to solving our planet's biggest conservation challenges. How exactly? In this episode, host Laurie Segall digs into the technology required to bring extinct species back from the dead, and the benefits Lamm believes de-extinction can have on our ecosystem. Could such an ambitious project reinvigorate national moonshot scientific goals? And, the real question on everyone’s minds: is this ‘Jurassic Park’ in real life? 

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AI Was My Stalker23 Apr 202600:36:24

She never used the app. She never spoke to its AI. She didn’t even know it existed. And yet an AI companion app called Sesame wouldn’t stop talking about her — telling users wild stories about who she was and what she had done. When the people using this app started to believe these made up stories and then tried to find her in the real world, that’s when she had to disappear. In this episode, host Laurie Segall speaks with the woman whose identity was hallucinated by AI. Together they unpack what she called “AI stalking”: the collision of two of the biggest problems in AI right now— hallucinations and LLM (Large Language Model) psychosis — and what happens to the human caught in the middle. There was no playbook for what happened to her. But her story may be less of an edge case than we think. 

 

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How to Hack Your Productivity Like a Silicon Valley CEO16 Apr 202600:37:57

If you’re looking at the headlines around AI with some trepidation or, honestly, you just don’t know where to start, but you want in, consider this episode your starter pack. Laurie Segall brings on her friend and go-to for all things tech, Andrew Yeung. Andrew is an entrepreneur, investor, startup advisor, and one of the most plugged-in people Laurie knows. In this episode, Andrew passes on the Silicon Valley secrets, the tools the CEOs are using, and what’s worth the hype. Andrew also opens up his full tech stack, the tools and apps he uses — and how he uses them — and Laurie and Andrew even demo one live. This isn’t just a conversation about innovation happening somewhere out there, it’s your invitation to actually benefit from it. 

 

Apps and tools mentioned in this episode: 

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The AI Therapist Will See You Now09 Apr 202601:13:31

This week, we’re exploring the rise of AI-powered mental health—and what it means as more people turn to machines for support in moments of vulnerability. Mostly Human host, Laurie Segall, talks with Neil Parikh, CEO and co-founder of Slingshot AI and Ash, an app designed specifically for mental health.

Ash is part of a growing wave of tools trying to meet a massive gap in care, as demand outpaces access to human therapists. But as these systems become more sophisticated—and more personal—the questions get harder. Where do they help most? Where do they fall short? And how far is too far when it comes to outsourcing emotional care to AI?

This episode also looks at something bigger: the emergence of a new kind of relationship—one that blurs the line between tool and companion, and reflects a broader shift toward more parasocial connections in our lives.

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The Power and Responsibility of Sam Altman02 Apr 202601:13:32

This week, Laurie Segall sits down exclusively with OpenAI CEO Sam Altman for his first interview since shutting down the Disney-partnered Sora and making the Department of War deal. From power to parenthood, tech addiction and AI acceleration, Laurie interviews Altman about AI’s human impact and the weight of OpenAI’s influence. In a wide ranging interview, Altman describes a near-term future where automated AI researchers could compress a decade of scientific discovery into a single year, fundamentally reshaping society and an era of AI abundance, where solo-founders can build billion-dollar companies with AI agents. But that innovation sits against a complex backdrop with fundamental human questions at stake. Altman addresses concerns over AI-related job loss and reveals what he thinks are AI-proof jobs. Altman, who is also a father, discusses parenting in the age of AI, when he plans to introduce his own product to his child, and how he believes AI could benefit kids in the long run. This is a  conversation with Sam Altman you're not going to hear anywhere else, where the tech titan answers some fundamental questions about control, innovation, consequences, and the world we'll leave behind for our children. 


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Parenting at the Speed of AI, with Dr. Becky26 Mar 202600:49:10

Parenting has always been messy. AI is trying to make it frictionless. In this debut episode of Mostly Human, longtime tech journalist Laurie Segall explores the human side of our rapidly evolving technological world with "Millennial Parent Whisperer," Dr. Becky. The clinical psychologist and founder of Good Inside talks about what happens when kids grow up in a world of shortcuts — where answers are instant, validation is constant, and discomfort can be avoided altogether. Laurie and Dr. Becky explore how AI is reshaping emotional development, the importance of “hard moments” in young lives, and how parents can tackle some of today’s trickiest problems from AI companions to deepfakes. But they also talk about how AI can be used for good and how the scariest-seeming tech threats become less intimidating when you simply focus on the human emotion behind it. Dr. Becky is here to give parents — and humans of all shapes — the scaffolding to face whatever comes next in tech (and life).

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Introducing Mostly Human, a Tech Podcast Through a Human Lens19 Mar 202600:02:19

We’re living through one of the most extraordinary tech accelerations in human history. But too often, it can feel like tech is happening to us. Longtime tech journalist Laurie Segall is here to change that. Her new podcast, Mostly Human, explores the intersection of tech and humanity—offering a bridge to the future, one where we all benefit from innovation. Each week, Laurie brings you first-hand experiments with new trends, investigations into the darker corners of the internet, and rare-access interviews with both news-making tech titans and the people you don’t know yet—but should. Through immersive, in-depth conversations about the future, she tackles some of the defining questions of our time—leaving you with a sense of agency over fear, and a clearer view of how tech can actually work for you. Mostly Human is tech through the most important lens: the human one. Find new episodes every Thursday right here in this feed, starting March 26, 2026.

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Evernote Founder Wants to Save Us from Boring Video Calls06 Oct 202001:23:01

Our new hyperconnected lifestyles have revealed weaknesses in the technology we use every day. But new problems lead to new solutions. That’s where innovation comes from. Phil Libin is probably best known as the co-founder and former CEO of Evernote. These days he heads up a company called All Turtles, whose latest project mmhmm wants to save us all from the Zoom-apocalypse and revolutionize how we will work in the future. Phil sets a high ethical bar for the creators of new technology, including himself: It’s their responsibility to think about the intentional and unintentional impact of their products, he says. Not just the impact on the technology’s users, but also on people who don’t use it at all…

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Show Notes

*All Turtles

*mmhmm

*The Gray Area Newsletter #1, featuring Phil Libin

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Inside Facebook's Ambitious Plan To Build Out the Next Dimension29 Sep 202001:02:57

Facebook has ambitious plans for virtual reality. And Andrew “Boz” Bosworth is in charge of it all. He says we’ve only scratched the surface of how VR and AR technology will transform society. So what does that future look like? How do you make virtual interaction feel as natural as in-person interaction? How do you prevent harassment, without prohibiting intimacy? How will virtual spaces change the way we work? The way we learn? The way we play? And when it comes to your virtual self - who owns your identity? As Facebook dives head first into the next technological frontier, will they manage to avoid the mistakes of their past?


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Surveillance Tech & Biased AI: The ACLU Fights Back08 Jul 202001:05:24

What happens to our civil liberties when an algorithm is used by law enforcement to make an arrest? Even more concerning, what happens when that facial recognitiontechnology is racially biased? As we enter an age of ubiquitous surveillance, it’s minorities - especially people of color - who are disproportionately affected. The ACLU has recently filed a complaint on behalf of a Black man who was wrongfully arrested dueto faulty police facial recognition tech. It’s the first case in the US, but it’s unlikely to be the last because, according to the ACLU - the tech often can’t tell Black people apart. The organization that has been fighting for civil rights protections forover 100 years, is now calling on lawmakers nationwide to stop law enforcement use of facial recognition technology. For Susan Herman, it’s an extraordinary time to be president of the ACLU. Over the years, the American Civil Liberties Union has fought forfree speech, reproductive rights, and privacy. But as technology continues to muddy the waters, the tradeoffs become more complicated. Where do we draw the line between security and privacy? Herman says we must act now.————————————Show Notes

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The Future of Mindfulness, Love... and High-Stakes Poker02 Jul 202000:51:24

We’re bringing you three interviews from the first at-home edition of the Collision tech conference. Laurie chats with Headspace Co-founder and CEO Rich Pierson about the importance of mindfulness and how to live in the present amidst global uncertainty. Match.com CEO Hesam Hosseini and Plenty of Fish CEO Malgosia Green discuss how COVID-19 has transformed the world of dating. And lastly, entrepreneur and author Molly Bloom shares her incredible life story — one that you may be familiar with from the 2017 film Molly’s Game. She gives Laurie a peak behind the curtain of running one of the highest-stakes illegal poker games in history.


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Show Notes


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It's Time to Finally Fix Tech’s Diversity Problem08 Jun 202000:43:05

It's no secret to anyone: Tech has a major diversity problem. And it's not getting better. How do we finally start making the necessary changes to fix the glaring inequity in Silicon Valley? How do we change the makeup of board members, make companies more diverse, and start putting our money where our mouth is? Venture Capitalist Sarah Kunst is someone who’s not afraid to speak out. She’s been leading a discussion on minorities in tech for a long time. She's made it her life’s work to change things for the better. These are times of listening and learning. We all have to do a better job of informing ourselves, listening to others, and changing our behavior. So let’s listen to Sarah Kunst.


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Show Notes

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Free Speech: The Firestorm Tech Can No Longer Afford to Ignore05 Jun 202000:47:32

We are living through pretty surreal times... Most of the country is still shut down due to COVID-19. Over the last few days we’ve seen protests and riots across the country following the police killing of George Floyd, an unarmed black man. All while Facebook faces a crisis of its own: internal and external revolt in response to the company’s inaction towards President Trump’s inflammatory posts.

Barry Schnitt was Facebook’s Director of Communications for four years and his recent blog post criticizing the company’s stance on free speech has gotten a lot of attention — especially since Facebook employees, even former ones, are normally so tight-lipped. He talks to Laurie about why both current and former employees are speaking out.

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Joseph Gordon-Levitt & Jared Geller on Creativity in Chaos04 May 202001:16:56

You probably know Joseph Gordon-Levitt as an actor from films like Looper, Snowden, and 500 Days of Summer. But he’s also an entrepreneur. In 2005, Joe and his brother started HitRECORD -- it was a simple website where he could post things he was making. In 2010 he opened it up. He and his friend Jared Geller turned HitRecord into an online platform where people from all over the world could come together to collaborate. Since then, they’ve pivoted from a production company to a tech company, with a vision to help us move away from aimlessly scrolling, towards creating together.


We’re in a moment filled with anxiety and fear. It’s hard to find any kind of silver lining. But if we had to, it might be this: moments of pain and uncertainty have historically led to incredible art and creativity. So what will be the legacy of the technology built in this age? In this episode of First Contact, Joseph Gordon-Levitt and co-founder Jared Geller talk to Laurie about finding creativity in difficult times.


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Show Notes

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TaskRabbit Founder: Finding Opportunity in Uncertainty27 Apr 202001:06:53

The 2008 recession was a devastating time for many Americans. But amidst the chaos, it was also the breeding ground for a new creative class: Developers who coded their visions into reality. Uber and Lyft redefined transportation, Airbnb shook up the travel industry, and TaskRabbit helped pave the way for the gig economy. In many ways, the uncertainty we face today mirrors that crisis. TaskRabbit’s founder Leah Solivan joins the show to explain why she believes founding her company in harsh conditions was key to her success, and why the pandemic provides a similar opportunity for innovation.


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Show Notes

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Covid-19 Has Made Us Slaves to Tech: Will We Ever Escape?20 Apr 202000:46:33

For a long time, we tried to limit our screen time. But now we’ve gone all in. We’re living in isolation, more reliant than ever on technology for human connection. So let’s look at technology through a more philosophical lens: Are we now slaves to our devices? Could tech companies use the same persuasion tactics they use to get us to click... to help save lives? How will we balance protection and privacy?


Aza Raskin is the co-founder of The Center for Humane Technology. There’s no one better to talk about the intersection of philosophy and technology. Aza returns to the show to chat with Laurie about the long-term ramifications of our newfound digital lives.


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Show Notes


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Let’s Talk About Sex (During a Pandemic)13 Apr 202000:46:05

All around the world, people are now living in isolation. Many of us are confronting this experience alone. Physical interaction is now a liability. What does this mean for one of humanity’s most important forms of connection — sex? And how can we continue to meet our fundamental need for intimacy during these times? Laurie looks at what all this on-screen interaction will mean for the future of sex. Could tech eventually replace human touch? Will people develop relationships with machines? From teledildonics to virtual girlfriends, sextech expert Bryony Cole talks sex in isolation and the future of love.


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Show Notes


O.School

End of Life Care Machine

Wheel Of Foreplay

Sex Hacker Kenneth Play

Esther Perel

OMGyes

Mend (chatbot)

Replika

Roman (chatbot)

Slutbot

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"People Ahead of Profit:" How to Lead in Uncertain Times06 Apr 202000:55:12

Jerry Colonna is fondly known as the CEO whisperer. He coaches some of the world's biggest entrepreneurs - like the former CEO of Etsy and the folks who started Gimlet Media. He helps business leaders navigate uncertainty and chaos. At a time when the coronavirus crisis is devastating the economy and millions of people's lives have been changed forever, the future is nothing but uncertain. Jerry's whole ethos is centered around the concept: better humans make better leaders. And there's never been a more critical time for humanity or leadership. Jerry is the expert. His message is simple: Show up.




Show Notes

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Quarantine Diaries30 Mar 202000:37:42

While we all stay inside, each one of us is living our own story. Many of us are coping with the painful realities of a society in isolation. Jobs lost. Weddings canceled. Loved ones sick, or worse. We are confronting a new reality, and an uncertain future. First Contact host Laurie Segall has been in quarantine for weeks, and she’s been thinking a lot about community. Human connection. And then she had an idea: What if we cold-called strangers in quarantine, and just listened to what they had to say? About life, isolation, their hopes, and fears? Here’s what happened...

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It’s "Boss Level Mode” Time: Remote Work Pioneer Matt Mullenweg On Staying Productive19 Mar 202000:37:04

Workouts between calls. Meditation apps. A desk candle to boost productivity. Work-from-home hacks for all of us, as we self-isolate and practice social distancing to slow the spread of Coronavirus.


Matt Mullenweg, founder of WordPress and Automattic, was an early evangelist of remote work. Back in the early 2000s, many of his first hires at Wordpress were people he had never met in person. Today, Automattic has nearly 1,200 employees spread across 75 countries around the globe.


With the pandemic now forcing many companies to unexpectedly adopt similar policies, Matt gives Laurie advice on transitioning to this new lifestyle and answers listener questions on the best ways for employees and employers to stay productive.


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Show Notes


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Ev Williams on Coronavirus and the 'Extreme' Tech of the Future16 Mar 202001:09:41

Ev Williams is the entrepreneur behind Twitter, Blogger, and publishing platform Medium -- three companies that helped shape the modern Internet. As we grapple with the impact of Coronavirus, these digital platforms are playing an even larger role in our ability to connect with one another. Ev weighs in on how all our lives could change in the short term and what the longer term future may hold for technology and media…

Will Augmented Reality project images onto our eyeballs? Will Silicon Valley ever move beyond the attention span economy? Will our lives start to resemble more of a video game than real-life? There's a lot to explore. And no one better than Ev Williams to help make sense of it all.

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Show Notes

Laurie and Ev’s first contact

Jonathan Livingston Seagull, a book from Ev’s childhood

Full Episode Transcript

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Coronavirus: The Rise of Isolation Tech09 Mar 202000:46:58

The rise of “cloud clubbing” from your living room, as people are ordered to stay inside. Digital raves. Virtual connection as a means to deal with an isolation bubble.


As people in China grapple with an uneasy reality, isolation, and the uncertainty around the Coronavirus, a new trend is emerging: the rise of Isolation Tech. Concerts are canceled. People are rethinking physical interaction. Nightclubs are shut down. So millions are meeting in digital clubs in the cloud where they can watch live DJ sets on Chinese apps. Welcome to The Matrix.


Instead of finding ways to depart from their devices, people have gone all in, living life in a digital bubble. Entrepreneur Zander Shapiro, who has lived in Beijing for nine years, describes his new reality in "the bubble" -- days beginning with virtual work outs, afternoons filled with remote meetings, and evenings where he joins a virtual concert, meeting other avatars for connection. He calls this moment an excellent "experiment" of what's to come in tech. Expect more extremism, less humanity, and money pouring into the business of virtual connection.

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Inside the minds of trolls02 Mar 202001:00:02

Who are the people who spread online disinformation? The so-called trolls you hear about in the news whose jobs are to distort facts and create chaos? Camille Francois knows them well. She’s the chief innovation officer at Graphika - a social media analytics firm hired by major companies to identify and fight online disinformation. Her team was a big part of uncovering the extent of Russian influence during the 2016 election. She spends her time in the darkest corners of the Internet taking on one of the most extraordinary digital threats of our time… But it might just be her humanity that gives her an edge.

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