Gordon H. Guyatt, MD, MSc, discusses Assessing the Strength of Recommendations: The GRADE Approach with Per Olav Vandvik, MD, PhD.

Related Content:

• How to Interpret and Use a Clinical Practice Guideline or Recommendation

Host Gordon Guyatt, MD, MSc, discusses Understanding and Applying the Results of a Systematic Review with M. Hassan Murad, MD, MPH.

Related Content:

• How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient Care
• Acute Treatments for Episodic Migraine in Adults

Gordon Guyatt, MD, discusses Misleading Presentations of Clinical Trial Results with Victor Montori, MD

Related Content:

• Misleading Presentations of Clinical Trial Results with Dr Victor Montori
• When Can Intermediate Outcomes Be Used in Clinical Trials?
• When Guidelines Recommend Shared Decision-making

Anne M. Holbrook, MD and Gordon Guyatt, MD, discuss Surrogate Outcomes from the JAMA Users' Guides to the Medical Literature

Related Content:

• When Can Intermediate Outcomes Be Used as Surrogate Outcomes?
• FDA Acceptance of Surrogate End Points for Cancer Drug Approval: 1992-2019
• What Constitutes a Valid Surrogate End Point in Cancer Clinical Trials?

Interview with Yun Liu, author of How to Read Articles That Use Machine Learning: Users' Guides to the Medical Literature

JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" With William J. Meurer, MD, MS

Ed Livingston, MD, FACS, AGAF, discusses Dose-Finding Trials: Optimizing Phase 2 Data in the Drug Development Process with Kert Viele, PhD

Ed Livingston, MD, FACS, AGAF, discusses Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Amy Kaji, MD, PhD

Gordon Guyatt, MD, MSc, discusses Decision-making and the Patient with Victor Montori, MD, MSc.

Clinical researchers and biostatisticians use highly specialized language to help them discuss statistics and research methods efficiently. In 2019 JAMA published the JAMA Guide to Statistics and Methods, a book of short reviews that translate that specialized language and explain statistics and methods to a broad physician readership. The book's editors and authors, Edward Livingston, MD, and Roger J. Lewis, MD, PhD, discuss their approach to choosing statistical topics and their objectives in compiling the reviews into book format.

Purchase the JAMA Guide to Statistics and Methods at:

McGraw-Hill:                    ja.ma/StatsGuideMH

Barnes and Noble:           ja.ma/StatsGuideBN

Amazon:                            ja.ma/StatsGuideAmazon

Gordon Guyatt, MD, MSc, discusses the application of the results of systematic reviews and meta-analyses to individual patients with author Thomas Agoritsas, MD.

Dr Edward Livingston discusses How to Use a Subgroup Analysis with Dr Gordon Guyatt

Gordon H. Guyatt, MD, MSc, discusses Fixed-Effects and Random-Effects Models with M. Hassan Murad, MD.

Related Content:

• Random-Effects Meta-analysis

Dr Ed Livingston discusses Composite End Points with Gordon Guyatt

Dr Gordon Guyatt discusses Differential Diagnosis with Scott Richardson

Dr Gordon Guyatt discusses How to Use an Article About Genetic Association with Dr John Attia

Demetrios N. Kyriacou discusses How to Use an Article About Hypothesis Testing and Appropriate Interpretation of P Values with Dr George Tomlinson

Dr David Simel discusses Obstructive Sleep Apnea with Dr Kathryn A. Myers.

Dr Demetrios Kyriacou discusses How to Use an Article About Quality Improvement with Dr Eddy Fan.

Dr Demetrios Kyriacou discusses Network Meta-analysis with Dr Gordon Guyatt.

Dr Amy Thompson discusses the Principle of Intention to Treat and Ambiguous Dropouts with Dr Matthias Briel.

Dr Amy Thompson discusses Evidence-Based Medicine and the Theory of Knowledge with Dr Gordon Guyatt.

Dr Ed Livingston discusses Clinical Prediction Rules with Dr Thomas G. McGinn.

Gordon H. Guyatt, MD, MSc, discusses Adjusted Analyses in Studies Addressing Therapy and Harm with Thomas Agoritsas, MD, PhD.

Related Content:

• Adjusted Analyses in Studies Addressing Therapy and Harm

Dr Ed Livingston discusses Recommendations About Screening with Gemma Louise Jacklyn.

Dr Ed Livingston discusses How to Use a Noniferiority Trial with Dr Gordon Guyatt.

Dr Ed Livingston discusses Systematic Review and Meta-analysis with Dr M. Hassan Murad.

Joan Stephenson, PhD, discusses Understanding the Results: More About Odds Ratios with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Why Study Results Mislead with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Surprising Results of Randomized Trials with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Diagnostic Tests with Dr Toshi A. Furukawa.

Joan Stephenson, PhD, discusses Confidence Intervals with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Prognosis with Dr Adrienne Randolph.

Joan Stephenson, PhD, discusses Philosophy of Evidence-Based Medicine with Dr Victor Montori.

Gordon Guyatt, MD, MSc, discusses Spectrum Bias with Reem A. Mustafa. MD, MPH, PhD.

Joan Stephenson, PhD, discusses Harm (Observational Studies) with Dr Mitchell Levine.

Joan Stephenson, PhD, discusses Does Treatment Lower Risk?: Interview with Dr Roman Jaeschke.

Joan Stephenson, PhD, discusses Measuring Patients' Experience with Dr Toshi A. Furukawa.

Joan Stephenson, PhD, discusses N-of-1 Randomized Controlled Trials with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Randomized Trials Stopped Early for Benefit with Dr Victor Montori.

Joan Stephenson, PhD, discusses Finding the Evidence with Dr Ann McKibbon.

Joan Stephenson, PhD, discusses Summarizing the Evidence with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses The Process of Diagnosis with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses Therapy (Randomized Trials) with Dr Gordon Guyatt.

Joan Stephenson, PhD, discusses What Is the Question? with Dr Gordon Guyatt.

Gordon Guyatt, MD, MSc, discusses Discrimination and Calibration of Clinical Prediction Models with Ana Carolina Alba, MD, PhD.

Related Content:

• Discrimination and Calibration of Clinical Prediction Models With Dr Alba

Read Transcript

Joan Stephenson, PhD, discusses The 5As of the Health Information Cycle with Dr Robert Hayward.

Joan Stephenson, PhD, discusses Applying Evidence-Based Practice with Dr Robert Hayward.

Joan Stephenson, PhD, discusses The Origin of Evidence-Based Medicine and the Users' Guides to the Medical Literature with Dr Gordon Guyatt.

Dr Drummond Rennie discusses Introduction to JAMAevidence: the Fundamental Tools for Dealing With the Medical Literature and Making Clinical Diagnoses.