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On episode #117 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/29 – 10/12/26.

Hosts: Daniel Griffin and Sara Dong

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• Viral
• Influenza Vaccine Effectiveness Against Influenza A–Associated Hospitalization and Severe In-Hospital Outcomes Among Adults in the United States, 2024–2025 (CID
• Risk Factors for Hypoxia, Mechanical Ventilation, and Mortality in Lung Transplant Recipients Hospitalized with Respiratory Syncytial Virus: A Multicenter International Cohort Study (OFID)
• Bacterial
• R.E.M. – It's The End Of The World (YouTube)
• Mandatory infectious diseases consultation and consensus approach effective at lowering antibiotic duration in uncomplicated gram-negative bacteremia (Journal of Gastroenterology and Hepatology)
• Air contamination and cross-room transmission of carbapenem resistant Acinetobacter baumannii in ICU (Antimicrobial Stewardship & Healthcare Epidemiology)
• Uncovering an alternate pathway of antibiotic resistance in spore-forming bacteria (Nature Communications)
• Clinical Practice Guideline for the Diagnosis and Treatment of Urinary Tract Infection in Children From 8 Days to 5 Years of Age (Pediatrics)
• Shorter Antibiotic Duration for Pseudomonas Bacteremia: A Call for Future Trials (CID)
• Fungal
• The Last of US Season 2 (YouTube)
• Impact of a Large-Scale Mold Intervention in Public Housing on Asthma Emergency Department Visits (American Journal of Respiratory and Critical Care Medicine)
• A Candid Appraisal of Repeat Blood Cultures in Candidemia—Missed Detection or Incident Infection? (CID)
• Notes from the Field: Molecular Detections of Cladophialophora bantiana at a Clinical Reference Laboratory — United States, 2009–2026 (CDC: MMWR)
• Histoplasmosis in Pregnancy: A Review and Patient Perspective (OFID)
• Parasitic
• Flubendazole reduces emerging Dracunculus medinensis in dogs in Chad: Results from a two-year study (PLoS Neglected Tropical Diseases)
• Toxoplasma Transmission to the Fetus during the Periconceptional Period (AJTMH: American Journal of Tropical Medicine and Hygiene)
• Clinical and Laboratory Dynamics of Bear Meat-Associated Trichinellosis in Hokkaido, Japan (AJTMH: American Journal of Tropical Medicine and Hygiene)
• Clinical significance of Dientamoeba fragilis and Blastocystis: Lessons from clinical trials, cohort studies, and faecal microbiota transplantation — a narrative review (CMI: Clinical Microbiology and Infection)
• Miscellaneous
• A consensus-based guideline for personalized bacteriophage therapy (Nature Medicine)
• Diagnosis and Management of Infectious Encephalitis in Adults: Guidelines From the European Academy of Neurology and European Society of Clinical Microbiology and Infectious Diseases (European Journal of Neurology)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #116 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/16 – 9/21/26.

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• Viral
• Oya Virus in a Patient with Severe Hepatitis, Enteritis, and Coagulopathy (NEJM)
• Two Versus One COVID-19 Vaccine Dose After Prior SARS-CoV-2 Infection: A Nationwide Retrospective Cohort Study (OFID)
• Comparison of Silevimig, a Novel Bispecific Anti-Rabies Monoclonal Antibody, with Human Rabies Immunoglobulin for Post-Exposure Prophylaxis: A Phase III, Randomized, Double-Blind, Non-Inferiority Trial (CID)
• Bacterial
• R.E.M. – It's The End Of The World (YouTube)
• Companion Animals Harbour Globally Circulating Human-Associated Klebsiella pneumoniae Lineages and High-Risk Antimicrobial Resistance Clones (Transboundary and Emerging Diseases)
• Air contamination and cross-room transmission of carbapenem resistant Acinetobacter baumannii in ICU (American Journal of Infection Control)
• Economic Outcomes of Dalbavancin versus Standard Therapy in Staphylococcus aureus Bacteremia in the DOTS Randomized Clinical Trial (CID)
• Cephalexin Model-Informed Dosing Recommendations for Severe Infections: A Pooled Pharmacokinetic Analysis From Infancy to Adulthood (OFID)
• Initial Carbapenem Choice Versus Sustained Single-Group Therapy in the Albumin-Carbapenem Interaction (CID)
• Identification and Quantification of Pathogens in Pleural Fluid from Children with Complicated Pneumonia using the BioFire® FilmArray® Pneumonia Panel (Journal of Pediatric Infectious Diseases Society)
• Effectiveness of oral care for the prevention of non-ventilator hospital-acquired pneumonia (HAPPEN): a multicentre, stepped-wedge, cluster-randomised trial in Australia (LANCET: Infectious Diseases)
• Fungal
• The Last of US Season 2 (YouTube)
• Health Economic Analysis of the AMBITION Protocol for Human Immunodeficiency Virus–Associated Cryptococcal Meningitis in the United States (CID)
• Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis (NEJM)
• Parasitic
• Vampire bats in Belize harbor multiple Trypanosoma cruzi genotypes: Implications for parasite transmission at the wildlife–domestic–human interface (PLoS Neglected Tropical Diseases)
• Community-acquired coinfections in adults with severe imported malaria: a systematic review and meta-analysis (CMI: Clincial Microbiology and Infection)
• Treatment for Leishmaniasis using liposomal amphotericin for immune compromised patients (in Portguese(Brazil.gov))
• Reactivation of Cutaneous Leishmaniasis in a Rheumatoid Arthritis Patient Undergoing Tocilizumab Treatment (AJTMH: American Journal of Tropical Medicine and Hygiene)
• Efficacy and safety of alternative benznidazole and nifurtimox regimens for adults with chronic Trypanosoma cruzi infection (TESEO): an open-label, randomised, non-inferiority phase 2b trial (LANCET: Infectious Diseases)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #115 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/1 – 9/14/26.

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• Viral
• Immunogenicity of fractional one-fifth and one-half doses of 17DD yellow fever vaccine compared with full dose in children aged 9–23 months in Uganda: a phase 4, single-blind, randomised clinical trial (The LANCET)
• Early Antiviral Therapy in Pediatric Outpatients and Risk of Influenza-Related Hospitalization (Pediatrics)
• Beyond Koplik spots: aphthous-like ulcers as a novel enanthem in adolescent and adult measles (CMI: Clinical Microbiology and Infection)
• Bacterial
• A Ten-Year Trend of Antimicrobial Resistance in Pseudomonas aeruginosa From United States Medical Centers: Results From the INFORM Surveillance Program (2015–2024)(OFID)
• A Scenario-Based Survey of Clinician Recommendations for Follow-up Blood Cultures in Patients with Varying Risk of Persistent Gram-Negative Bacteremia (OFID)
• Should valve leaflet thickening be considered a characteristic lesion of infective endocarditis? (CID)
• Infective Endocarditis: Diagnosis, Antibiotic Therapy, and Management: A Scientific Statement From the American Heart Association (AHA|ASA: Circulation)
• IDSA/ESCMID 2026 Consensus Statements on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children (IDSA)
• Relationship between Antibiotic Prescription and Survival in Hospice (CID)
• Performance and Projected Impact of Synovial Fluid Polymerase Chain Reaction Testing for Patients Evaluated for Septic Arthritis (CID)
• Cefepime versus piperacillin-tazobactam for the treatment of Pseudomonas aeruginosa pneumonia (CID)
• Cefepime and Mortality A Systematic Review and Bayesian Meta-Analysis (JAMA: OPEN Network)
• Global and regional burden of colorectal cancer potentially related to Helicobacter pylori exposure: a risk attribution modelling study (BMJ Journals: eGastroenterology)
• A randomized controlled trial of cefiderocol versus standard therapy for Gram-negative bacterial bloodstream infections: Benefit and risk assessment using DOOR and generalized pairwise comparisons (CID)
• Fungal
• The Last of US Season 2 (YouTube)
• No survival benefit associated with antifungal therapy for respiratory Candida spp.: a single-center retrospective cohort study (OFID)
• The Role of 1-3-Beta-D-Glucan in Predicting Pneumocystis jirovecii Pneumonia in Immunocompromised Children (Journal of the Pediatric Infectious Diseases Society)
• Parasitic
• Miscellaneous
• Vaccination Coverage Among Adolescents Aged 13–17 Years — National Immunization Survey-Teen, United States, 2025 (CDC:MMWR)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #114 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/18 – 8/31/26.

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• Viral
• HPV Vaccination and Risk of Head and Neck Cancers: A Large Real-World Cohort Study (International Society for Infectious Diseases)
• Beyond the Acute Illness: Three Myths About Viral RespiratoryInfection (JID)
• Use of Nowcasting to Estimate Real-Time Transmission Trends During a Measles Outbreak — South Carolina, October 2025–March 202 (CDC: MMWR)
• IPOL (Package Insert)
• Effect of inactivated poliovirus vaccine on nasal mucosal immunity and pharyngeal shedding following novel oral poliovirus vaccine type 2 challenge: A randomized, open-label trial (JID)
• Bacterial
• Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis (NEJM)
• Clinical Practice Guidelines by Infectious Diseases Society of America 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections–Introduction and Methods (CID)
• Society of America: 2025 Guideline on Management and Treatment of Complicated Urinary Tract Infections–Selection of Antibiotic Therapy for Complicated Urinary Tract Infections (CID)
• Clinical Practice Guidelines by Infectious Diseases Society of America: 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections – Timing of Intravenous to Oral Antibiotics Transition for Complicated Urinary Tract Infections (CID)
• Clinical Practice Guidelines by Infectious Diseases Society of America (IDSA): 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections–Duration of Antibiotics for Complicated UTI (CID)
• Infective Endocarditis in Solid Organ and Haematopoietic Stem Cell Transplant Recipients (E-IPA Study): a propensity-score-matched retrospective cohort study (CID)
• Evaluation of Changes in Staphylococcus and Enterococcus Resistance Following Reduced Restrictions on Daptomycin and Linezoli (OFID)
• Comparison of VPM1002 with BCG in the prevention of tuberculosis in newborn infants: a multicentre, double-blind, randomised, phase 3, non-inferiority trial (LANCET: Infectious Diseases)
• Fungal
• The Last of US Season 2 (YouTube)
• Containment of a Candidozyma auris Outbreak in an Acute Care Hospital using a Comprehensive Screening and Surveillance Program (CID)
• Molecular Evidence of Autochthonous Environmental Acquisition of Fonsecaea Pediatric Infection in the United States (OFID)
• Challenging the concept of uncomplicated candidemia for shorter courses of antifungal therapy (OFID)
• Parasitic
• Miscellaneous
• Reliability of Physical Examination Findings in Youths Diagnosed With Pneumonia (JAMA)
• Recombinant shingles vaccination and the risk of cardiovascular events (Nature Medicine)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #113 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/4 – 8/17/26.

Hosts: Daniel Griffin and Sara Dong

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• Viral
• Two-year durability of MVA-BN vaccine-induced antibodies and the risk of Mpox breakthrough infections among high-risk populations: a prospective, longitudinal study (CMI: Clinial Microbiology and Infection)
• Notes from the Field: Potential Infant HIV Exposure from Donated Breast Milk Received Through Social Media — Santa Clara County, California, May 2025–January 2026 (CDC: MMWR)
• Bacterial
• Associations Between QuantiFERON-TB Gold Plus IFNγ Concentrations and Progression to Symptomatic Tuberculosis in Global High-Burden TB Settings (OFID)
• Cefadroxil as Oral Transitional Therapy for Gram-Positive Bacteremia With or Without Non-Vertebral Osteomyelitis: A Multicenter Retrospective Cohort Study (OFID)
• Efficacy of beta-lactam monotherapy versus clindamycin or addition of metronidazole in peritonsillar abscess – an observational cohort study with a focus on Fusobacterium necrophorum (CMI: Clinial Microbiology and Infection)
• A novel RNA nucleic acid amplification test more accurately distinguishes active Clostridioides difficile infection from colonization (CID)
• The Clean Margin in Diabetic Foot Osteomyelitis: Conceptual Appeal, Practical Uncertainty (CID)
• Rising Incidence of New Delhi Metallo-β-Lactamase–Producing Carbapenem-Resistant Enterobacterales, 10 US Sites, 2018–2023 (OFID)
• Association of anti-anaerobic antibiotics with mortality and the gut microbiome: a sub-study of the BALANCE randomized clinical trial (CID)
• Fungal
• The Last of US Season 2 (YouTube)
• Coccidioidomycosis Testing Among Patients Hospitalized With Community-Acquired Pneumonia (OFID)
• Parasitic
• Human Myiasis Resulting from Reemergence of Cochliomyia hominivorax Screwworm, Mexico, 2025–2026 (Emerging Infectious Diseases)
• The origin, history, and resistance architecture of an invasive urban malaria mosquito in Africa (Science)
• Clinical, molecular, and in vitro evidence of artemisinin partial resistance in Ethiopian Plasmodium falciparum: a prospective, multisite, surveillance (LANCET: Infectious Diseases)
• Miscellaneous
• What's in a Name? Etymology and History of Antibacterials and Antifungal (IOFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #112 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/20 – 8/3/26.

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• Viral
• The genomic identity of early smallpox in South America (Science)
• Telltale DNA: First direct evidence found that the Spanishbrought smallpox to the Inca (CIDRAP)
• Phase 3 Trial of Weekly Oral Islatravir–Lenacapavir for HIV-1 Treatment (NEJM)
• Early Transcriptional Signature in Chikungunya PredictsChronic Arthralgia and Reveals Deficient Antiviral Response (JID)
• Bacterial
• IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections (IDSA)
• Doxycycline in the treatment of outpatient mild community-acquired pneumonia: a propensity-matched retrospective cohort study (CMI: Clinical Microbiology and Infection)
• Detection of pathogens in the gut microbiome priorto bloodstream infection in children with acute myeloid leukemia or mature B-cell non-Hodgkin lymphoma (Journal of Pediatric Infectious Diseases Society)
• Fungal
• The Last of US Season 2 (YouTube)
• Active Surveillance for Invasive Mold Disease — Four Hospitals, Atlanta, Georgia, 2020–2024 (CDC: MMWR)
• Does the Evidence Support High-Dose Liposomal Amphotericin B in the Treatment of Mucormycosis? (JID)
• Miscellaneous
• Evaluation of the impact of a novel surgical handwashing method on reformation of microbial flora on surgeons' hands (Infection Control & Hospital Epidemiology)
• Association Between First MMR Vaccination Before Age 2 Years and Childhood Autism in a U.S. EHR Cohort of 2.5 Million Children (Journal of Pediatric Infectious Diseases Society)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #111 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/7 – 7/20/26.

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• Viral
• Impact of HIV-1 RNA Assay Selection on Low-Level Viremia and Clinical Trial Endpoint Interpretations (CID)
• Seroprevalence of Measles, Mumps, Rubella, and Varicella-Zoster Virus Antibodies—United States, 2017–March 2020 (JID)
• Concordance between nasopharyngeal swab and bronchoalveolar lavage PCR for respiratory viruses (CMI: Clinical Microbiology and Infection)
• Influenza vaccine effectiveness against outpatient acute respiratory illness with laboratory-confirmed influenza, United States, 2024–25 season (CID)
• Bacterial
• Clinical Impact of the BIOFIRE FILMARRAY Pneumonia Panel in the Veterans Affairs Healthcare System: A Difference-in-Differences Study (CID)
• Routine serial follow-up blood cultures after a negative result within 48 hours of methicillin-susceptible Staphylococcus aureus bacteremia: low yield, high cost (CID)
• Skipping to conclusions: Is one negative follow-up blood culture sufficient in Staphylococcus aureus bacteremia? (CID)
• Clinical Features of Clostridial Necrotizing Soft-Tissue Infections: Analysis of a Prospective Scandinavian Cohort Study(OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Molecular Epidemiology of Candidozyma auris Within a Case Cluster in North-Central Florida: Diverse Origins and Long-term Persistence ofStrain (OFID)
• Characteristics of Mortality in HIV-negative Cryptococcosis Patients: Analysis of a Cohort of 743 Patients (OFID)
• Parasitic
• Positive Strongyloides Serology: A Descriptive Analysis Across Geographically Distinct Academic Medical Centers (Transplant Infectious Diseases)
• Miscellaneous
• Community-acquired pneumonia: imperfect tests, imperfect clinicians or both? (CMI: Clinical Microbiology and Infection)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #110 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 6/23 – 7/6/26.

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• Viral
• Oseltamivir Resistance in Human Influenza A(H5N1) and A(H7N9) Infections: a mini review (OFID)
• Analysis of Viral Blips Through Week 192 of the DRIVE-FORWARD and DRIVE-AHEAD Phase 3 Studies of Doravirine-Based Regimens in Adults Living With Previously Untreated HIV-1 (OFID)
• Bacterial
• Impact of Multiplex PCR Blood-Culture Identification Panels on Clinical Outcomes, Antimicrobial Stewardship, and Economic Impact in US Hospitals: A Systematic Review and Meta-Analysis (OFID)
• Legionellosis Outbreaks Associated with Two Hotels — U.S. Virgin Islands, October 2024–April 2025 (CDC: MMWR)
• Impact of Methicillin Resistance on Outcomes of Staphylococcus aureus Bacteremia at a U.S. Center, 2023–2024 (OFID)
• Procalcitonin to Guide 7 vs 14 Days of Antibiotics in Bloodstream Infections (JAMA:Open Network)
• Fungal
• The Last of US Season 2 (YouTube)
• Comparing rapid molecular and culture methods for detecting fungal contamination in healthcare environments (Infection Control and Hospital Epidemiology)
• Surveillance for Candida auris — United States, 2022–2024 (CDC: MMWR)
• Parasitic
• Alpha-gal Immunoglobulin E Seroprevalence Among Blood Donors — 10 States, 2024–2025
• (CDC: MMWR)
• Schistosomiasis vaccine SchistoShield induces functional immune memory responses in US and African populations (njp: Vaccines)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #109 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/4 – 6/22/26.

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• Viral
• CMV viraemia is associated with mortality among children with HIV starting antiretroviral therapy in sub-Saharan Africa (CID)
• Bacterial
• Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia(NEJM)
• A fatal case of Legionella micdadei prosthetic valve endocarditis diagnosed by plasma microbial cell-free DNA metagenomic sequencing (LANCET: Infectious Diseases)
• Legionnaires Disease Associated with a Private-Use Hot Tub in a Vacation Rental Property — New York, October 2024–April 2025 (CDC: MMWR)
• Notes from the Field: Case of Legionnaires Disease Associated with a Home Device Used to Mix Powdered Infant Formula — United States, 2025 (CDC:MMWR)
• Duration of antibiotic therapy for bacteremia in immune compromised hosts—a post hoc subgroup analysis of the BALANCErandomized clinical trial (CMI: Clinical Microbiology and Infection)
• FDA approves first oral carbapenem therapy for complicated urinary tract infections (FDA)
• Oral Tebipenem Matched IV antibiotic for complicated UTIs in Phase III Trial (MEDPAGE Today)
• US FDA approves GSK's oral antibiotic for drug-resistant UTIs (Reuters)
• Anti–Methicillin-Resistant Staphylococcus aureus (MRSA) Cephalosporins Plus Daptomycin as Initial Therapy for MRSA Bacteremia: Does a "Hit Hard and Fast" Strategy Improve Outcomes? (CID)
• Fungal
• The Last of US Season 2 (YouTube)
• Oral Wash PCR Improves the Diagnosis of Pneumocystis Pneumonia in Immunocompromised Patients Without HIV: A Prospective Multicenter Study (CID)
• Miscellaneous
• Foodborne Disease Outbreaks Associated with Marine Toxins — Foodborne Disease Outbreak Surveillance System, United States, 2011–2023 (CDC: MMWR)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #108 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/21 – 6/3/26.

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• Viral
• Performance of five mpox antigen-based rapid diagnostic tests tested on lesion swabs from patients with suspected mpox from the Kinshasa province of DR Congo: a diagnostic accuracy study (LANCET: Infectious Diseases)
• A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D (NEJM)
• First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (CMI: Clinical Microbiology and Infection)
• Chikungunya Vaccines for Travelers: Unanswered Pragmatic Questions Persist (JID)
• Bacterial
• Early Discontinuation of Empiric Antibiotics in Pediatric Haploidentical Hematopoietic Cell Transplant Recipients with Febrile Neutropenia (CID)
• Methicillin-Resistant Staphylococcus aureus Nasal Swab Utilization as a Predictor for Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections: A Systematic Review and Meta-analysis (OFID)
• Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin: A Randomized Controlled Trial (CID)
• Fungal
• The Last of US Season 2 (YouTube)
• Donor-derived and nosocomial-acquired Candida auris transmission involving solid organ transplant recipients (Infection Control and Hospital Epidemiology)
• Parasitic
• Development of a Phase 1 Cryptosporidiosis Controlled Human Challenge Model in Healthy Volunteers Using Current Good Manufacturing Practice Cryptosporidium Parvum Oocysts and Conducted Under an Investigational New Drug Application (JID)
• Miscellaneous
• Childhood VaccineHesitancy(NEJM)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #107 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/7 – 5/20/26.

Host: Daniel Griffin and Sarah Dong

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of Puscast!

• Viral
• FDA Grants Accelerated Approval to Gilead's Hepcludex® (bulevirtide-gmod), the First and Only Approved Treatment for Chronic Hepatitis Delta Virus (HDV) (Gileadl)
• A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D(NEJM)
• Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD) (NLM: ClinicalTrials.gov)
• Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM)
• Quick takes: Another hantavirus case, polio in 3 countries, NIAID head steps down (CIDRAP)
• Dolutegravir Reduces Human T-Cell Lymphotropic Virus Type 1 Proviral Load and Improves Neurological Outcomes in a Phase 2 Controlled Trial (CID)
• Dolutegravir Appears to Lower Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) Proviral Load: The Emerging Rational Approach to Treatment of HTLV-1–Associated Myelopathy (CID)
• Use of Dolutegravir for treatment of HTLV-1 (CID)
• Use of dolutegravir to treat people living with HTLV-1-associated myelopathy (HAM) (CID)
• Bacterial
• Urinary Tract Infection (UTI)-free and Recurrent UTI (rUTI)-Free Survivals Following Bladder Electrofulguration in Women With a History of Antibiotic-Refractory rUTI (OFID)
• Azithromycin for Preschoolers with Wheezing in the Emergency Department (JAMA)
• Rapid Respiratory Microbiological Point-of-Care Testing and Antibiotic Use in Primary Care (JAMA Internal Medicine)
• Fungal
• The Last of US Season 2 (YouTube)
• Changes in Epidemiology of Candidemia in the United States With a Focus on Candida auris (CID)
• Parasitic
• Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme (The LANCET)
• Ivermectin-Benzimidazole Prescribing Following Celebrity Endorsement  (JAMA Network OPEN)
• Febrile Temperature Augents Ring-stage Plasmodium falciparum Adhesion to Brain Endothelial Cells (JID)
• An Increase in Imported Plasmodium vivax Malaria in New York City: Clinical and Demographic Trends Following Recent Migration (OFID)
• Miscellaneous
• The State of Physician Leadership (WittkKieffer)
• Infectious Diseases Fellowship Curriculum: IDSA Training Program Directors Community of Practice (TPDCOP), Curricular and Educational REsources Workgroup (CREW) (CID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #106 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/23 – 5/6/26.

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• Viral
• Andes hantavirus outbreak in cruise ship, 11 May 2026(European Centre for Disease Prevention and Control)
• 2026 Multi-country Hantavirus Cluster Linked to Cruise Ship (CDC: Health Alert Network)
• "Super-Spreaders" and Person-to-Person Transmission of Andes Virus in Argentina (NEJM)
• Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID)
• We Dissent: Lessons From the 2025 Community-Acquired Pneumonia Guidelines (CID)
• Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Paediatric Patient (OFID)
• Impact of Respiratory Syncytial Virus Immunization on the Rate of Pediatric Acute Otitis Media: A Time-series Analysis (CID)
• Bacterial
• Performance of a rapid, visual fingerstick serology self-test for Helicobacter pylori detection and typing: A prospective multicenter diagnostic accuracy study (CMI: Clinical Microbiology and Infection)
• Real-world effectiveness of 20-valent pneumococcal conjugate vaccine against all-cause outcomes among Medicare beneficiaries aged 65 years and older in the USA: a retrospective cohort study (LANCET: Infectious Diseases)
• Beta-Lactam plus Azithromycin or Doxycycline versus Fluoroquinolones in Hospitalized Adult Patients with Community-Acquired Pneumonia: A Systematic Review and Network Meta-Analysis (OFID)
• Syphilis and the risk of stroke: a nationwide, population-based matched cohort study (CMI: Clinical Microbiology and Infection)
• Reducing Bacterial Contamination of Blood Bags with a Double Knot (NEJM)
• Effectiveness and safety of daptomycin versus vancomycin in methicillin-resistant Staphylococci left-side infective endocarditis. Results from a nationwide prospective multicenter cohort. (CMI: Clinical Microbiology and Infection)
• Fungal
• The Last of US Season 2 (YouTube)
• Non-intravenous Amphotericin B: A Review of Localized Administration Routes (Infectious Diseases and Therapy)
• Parasitic
• Duration and association with protection of NANP-repeat-specific and C-terminus-specific anti-circumsporozoite protein IgG responses following RTS,S/AS01E vaccination: an observational ancillary immunological study of a phase 3 clinical trial (LANCET: Infectious Diseases)
• Combined Oral Ivermectin and 5% Permethrin Cream to Treat Severe Scabies (NEJM)
• Miscellaneous
• Interest in Infectious Diseases Among Internal Medicine Resident Physicians: Results From a Nationwide Survey (CID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #105 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/9 – 4/22/26.

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• Viral
• Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients (NEJM)
• Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir (NEJM)
• Paxlovid doesn't reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows (CIDRAP)
• Risk of Guillain–Barré Syndrome after Laboratory-Confirmed Dengue Infection (NEJM)
• A New Type of Nonsuppressible Viremia Produced by HIV-Infected Macrophage (JID)
• First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID)
• Bacterial
• Tetanus Surveillance — United States, 2009–2023 (CDC: MMWR)
• Notes from the Field: Tetanus in Four Children — Idaho, Minnesota, Missouri, and Wisconsin, 2024 (CDC: MMWR)
• Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults (JAMA)
• Efficacy and safety of vancomycin versus 13 alternatives in MRSA-confirmed skin and soft tissue infections: a meta-analysis of 39 randomized controlled trials (Infection)
• Methicillin-Resistant Staph Aureus (MRSA) Nasal Swab Utilization as a Predictor for MRSA Skin & Soft Tissue Infections: A Systematic Review and Meta-analysis (OFID)
• Practice variation, outcomes and definitions of suppressive antimicrobial therapy for prosthetic joint infections: a systematic review and expert consensus statement (CIC)
• Efficacy and safety of VPM1002 and Immuvacin preventing tuberculosis: phase 3 randomised clinical trial (PreVenTB trial) (BMJ)
• Comparison of Ceftolozane-Tazobactam and Ceftazidime-Avibactam in the Treatment of Multidrug-Resistant/Difficult-to-Treat Resistant Pseudomonas aeruginosa Infections: A Systematic Review and Meta-analysis (CID)
• Do C-Reactive Protein Measurements Predict Treatment Failure in Native Vertebral Osteomyelitis? (OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Rising burden of severe pediatric coccidioidomycosis: a 25-year single-center study (Journal of the Pediatric Infectious Diseases Society)
• Candida glabrata emerges as the most common cause of candidemia: analysis of a large hospital-based database, United States, 2016–2024 (CID)
• Test Performance and Clinical Utility of the cobas® eplex Blood Culture Identification Fungal Pathogen Panel (OFID)
• Cutaneous Paraconiothyrium cyclothyrioides Infection in Lung Transplant Recipient, Georgia, USA (Emerging Infectious Diseases)
• Azole Resistance in Aspergillus fumigatus From Diverse Environments in Ohio, United States, Is Primarily Driven by TR34/L98H and TR46/Y121F/T289A Environmental Signatures (OFID)
• Parasitic
• Fatal Donor-Derived Disseminated Acanthamoeba Infection in a Liver Transplant Recipient (OFID)
• Miscellaneous
• Host–microbiome archetypes differentiate infection from pathogen carriage in the human lower airway (Nature Communications)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #104 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/26 – 4/8/26.

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• Viral
• Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis (Neurology)
• Bacterial
• Direct Oral Challenge for Penicillin Allergy: The International Network of Antibiotic Allergy Nations (iNAAN) Study (CID)
• Inhaled Antibiotics to Treat Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis (Critical Care Medicine)
• ATS/IDSA 2016 Clinical Practice Guidelines for the Management of Adults With Hospital-Acquired and Ventilator-Associated Pneumonia (ISDA)
• Risk of Invasive Meningococcal Disease in Children Aged <11 Years in the United States (OFID)
• American Society of Breast Surgeons, Society of Breast Imaging, and College of American Pathology 2025 Guidelines for the Management of Infectious and Inflammatory Lesions of the Breast (JAMA Surgery)
• Tularemia Antimicrobial Treatment and Prophylaxis: CDC Recommendations for Naturally Acquired Infections and Bioterrorism Response — United States, 2025 (CDC: MMWR)
• Effectiveness of Doxycycline in Combination With Other Antibiotics for Gram-Positive Periprosthetic Joint Infections: A Causal Inference Study (OFID)
• Reply to Dissent: Guidelines for Management of Community-Acquired Pneumonia (CID)
• VancObituary: A summary of a life well lived and a death well timed (Journal of the Pediatric Infectious Diseases Society)
• Reports of My Demise Have Been Greatly Exaggerated (Journal of the Pediatric Infectious Diseases Society)
• Fungal
• The Last of US Season 2 (YouTube)
• Parasitic
• Red Blood Cell Exchange Transfusion for Severe Babesiosis (JAMA Internal Medicine)
• Mapping Hospitals That Treat Severe Malaria Cases in the United States: Evidence to Inform Health Systems Strategies for Intravenous Artesunate Supply (CID)
• Artesunate Treatment of Severe Malaria in Nonendemic Countries: When, Where, How, and What Now? (CID)
• Attention for Compliance: Visual Media in Second World War Anti-Malaria Efforts (AJTMH: American Journal of Tropical Medicine and Hygiene)
• Screening and Reactivation of Chagas Disease Among Solid Organ Transplant Candidates and Recipients: A 10-Year Single Center Experience in Florida (Transplant Infectious Disease)
• Miscellaneous
• Phage Therapy in people with Cystic Fibrosis: a systematic review (Internation Journal of Infectious Diseases)
• Inverse Probability of Treatment Weighting (Google)
• Outcomes associated with empiric azithromycin use among patients hospitalized with non-severe community-acquired pneumonia: emulation of a target trial (CID)
• eConsult in infectious diseases: A narrative review (International Journal of Infectious Diseases)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #103 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/12 – 3/25/26.

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• Viral
• Probable Japanese Encephalitis Virus Transmission through Organ Transplantation (NEJM)
• Clinical Characteristics and Severity of Rhinovirus/Enterovirus–Associated Hospitalizations: A Multi-country Analysis from the Global Influenza Hospital Surveillance Network, 2017–2024 (OFID)
• Bacterial
• Eagle effect (Wikipedia)
• THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS (JEM)
• Linezolid versus clindamycin for toxin inhibition in severe skin and soft tissue infections: a systematic review and meta-analysis (Infection)
• Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (Critical Care Medicine)
• Caring for Adult Patients With Sepsis (JAMA)
• Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Intensive Care Medicine)
• Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Pediatric Critical Care Medicine)
• Caring for Pediatric Patients With Sepsis (JAMA)
• ACEP Will Not Endorse New Sepsis Guidelines from the Surviving Sepsis Campaign (American College of Emergency Physicians)
• Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With SepsisThe BLING III Randomized Clinical Trial (JAMA)
• Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis (Nature Communications)
• Survival trends in patients with difficult-to-treat, antibiotic-resistant, Gram-negative infections in the era of next-generation antibiotics in the USA: a retrospective cohort study (LANCET: Infectious Diseases)
• Fungal
• The Last of US Season 2 (YouTube)
• Empirical Antifungal Treatment of Critically Ⅲ Patients With Influenza-Associated Acute Respiratory Distress Syndrome: A Propensity Score Weighted Observational Study (CID)
• Clinical and Radiological Predictors of Invasive Fungal Sinusitis (OFID)
• Blood Cultures Contain Populations of Genetically Diverse Candida albicans Strains that May Differ in Echinocandin Tolerance and Fitness (JID)
• Can fluconazole be used to treat non-resistant Candida (Candidozyma) auris infections? Preclinical PK/PD data from a Galleria mellonella infection model (JID)
• Parasitic
• Na-GST-1 adsorbed on Alhydrogel co-administered with different Toll-like receptor agonists in hookworm-naive adults using a controlled human infection model in the USA: a phase 2, double-blind, randomised controlled trial (LANCET: Infectious Diseases)
• Miscellaneous
• Bridging the Gap: A Needs Assessment of Resources and Support for International Medical Graduates Navigating Visa-Related Career Decisions in Infectious Diseases (OFID)
• Number Needed to Treat (NEJM)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #102 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/26 – 3/11/26.

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• Viral
• Measles Outbreak — New Mexico, 2025 (CDC: MMWR)
• Epidemiology of HMPV and Other Respiratory Viral Infections Among Outpatients, 2016–2022 (OFID)
• Notes from the Field: Congenital Rubella Syndrome — Florida, 2025 (CDC: MMWR)
• Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine (Nature Medicine)
• Bacterial
• Clinical Outcomes in Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Infection: A Cohort Study (JID)
• Duration of therapy for Pseudomonas aeruginosa bacteremia – a post hoc subgroup analysis from the BALANCE randomized controlled trial (CID)
• Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries (CID)
• WHO recommends near point-of-care tests, tongue swabs, and sputum poolingfor TB diagnosis (WHO)
• Respiratory virus co-infection is a risk factor for adverse outcomes during Staphylococcus aureus bacteraemia (OFID)
• Balance Versus Bias: Correcting Misinformation About the 2025 ATS Community-Acquired Pneumonia Guidelines (CID)
• Fungal
• The Last of US Season 2 (YouTube)
• Immunomodulation in the Treatment of Disseminated Coccidioidomycosis (CID)
• Parasitic
• Comparison of six weeks doxycycline versus six weeks rifampicin or three weeks of the combination of doxycycline plus rifampicin in the treatment of onchocerciasis: a randomized, placebo-controlled, double-blind, phase 2 trial (OFID)
• Cutaneous Larva Migrans Within the United States Military Health System – Clinical Presentation and Association with Autochthonous Spread or International Travel (OFID)
• Miscellaneous
• Distinct prophage infections in colorectal cancer-associated Bacteroides fragilis (Communications Medicine)
• Rounding Styles on Inpatient Infectious Disease Consult Services: Impact on Education and Patient-Care Delivery (OFID)
• Possible quality indicators for clinical infectious diseases consultations – results from a hybrid Delphi-nominal group approach and scenario study (CMI: Clinical Microbiology and Infections)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #101 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 2/12 – 2/25/26.

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• Viral
• Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial (CID)
• Tecovirimat for the Treatment of Mpox (NEJM)
• Bacterial
• Multicounty Outbreak of Salmonella Agbeni Linked to Ice in a Cooler at a County Fair — Illinois, August 2024 (CDC: MMWR)
• Legionella Pneumonia in the Modern Era: Clinical Features and Predictors of Mortality (CID)
• Cefalexin use in UK acute pyelonephritis practice: unaddressed challenges in dosing, breakpoints and clinical evidence (Journal of Antimicrobial Chemotherapy)
• Is three really what we need? Relative effectiveness of benzathine penicillin G and doxycycline treatment regimens for late or unknown duration syphilis in 6 United States jurisdictions, 2016–2021 (CID)
• Show Me the "Mino:" In Vitro Efficacy of Minocycline on Clinical Gram-Negative Bacterial Isolates (Microbial Drug Resistance)
• Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection
• (JAMA Network)
• Microbial Flora in War Wounds from the Ukrainian Front Line (NEJM)
• Fungal
• The Last of US Season 2 (YouTube)
• Epidemiology of Aspergillosis Diagnoses in U.S. Adults using a National EHR Database, 2013-2023 (OFID)
• Parasitic
• State-of-the-Art Review: Chagas Disease—an Enduring Challenge (CID)
• Autochthonous Rat Lungworm Angiostrongylus cantonensis Infections in Accidental and Definitive Hosts, San Diego, California, USA (Emerging Infectious Diseases)
• Miscellaneous
• Ancient bacteria strain discovered in ice cave is resistant to some modern antibiotics(CNN)
• First genome sequence and functional profiling of Psychrobacter SC65A.3 preserved in 5,000-year-old cave ice: insights into ancient resistome, antimicrobial potential, and enzymatic activities (Frontiers in Microbiology)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #100 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/29/26 – 2/11/26.

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• Viral
• Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis (PNAS)
• Dengue Suppression by Male Wolbachia-Infected Mosquitoes (NEJM)
• Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine)
• Prevalence of CSF HIV VIRAL Escape and Associations With Neurocognitive Outcomes Among HIV-Associated Meningitis Survivors: A Cohort Study (OFID)
• Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM)
• Bacterial
• Extraintestinal Invasive Escherichia coli Infections in the US (JAMA Network OPEN)
• Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience (CID)
• US Emergency Department Visits forAntibiotic Adverse Drug Events in Children, 2019-2023 (Journal of the Pediatric Infectious Diseases Society)
• Fungal
• The Last of US Season 2 (YouTube)
• Albumin orchestrates a natural host defence mechanism against mucormycosis (Nature)
• Pseudo-Outbreak of Purpureocillium lilacinum Skin Infections at a Dermatology Clinic — Washington, 2024 (CDC: MMWR)
• Candida auris Testing by the Antimicrobial Resistance Laboratory Network, United States, 2022–2023 (Emerging Infectious Diseases)
• Parasitic
• Trichinellosis: A zoonosis that still requires vigilance (PLoS Neglected Tropical Diseases)
• Trichinellosis after Raw Bear Eyeball Consumption (AJTMH: American Journal of Tropical Medicine and Hygiene)
• Moving Scabies Under Video-Dermoscopy (AJTMH: American Journal of Tropical Medicine and Hygiene)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #99 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/15/26 - 1/28/26.

Host: Daniel Griffin and Sarah Dong

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• Viral
• Symptomatic and asymptomatic norovirus infections in early life; The PREVAIL Cohort, 2017-2020 (CID)
• Bacterial
• Xenodiagnosis to search for Borrelia burgdorferi after antibiotic treatment of Lyme disease: a prospective cohort study (CID)
• Diagnostic Yield of Repeat Blood Cultures and Risk Factors for Bloodstream Infection in Persistent Febrile Neutropenia (CID)
• Methodology Misrepresented: Correcting the Record on the ATS Community-acquired Pneumonia Guideline Process (CID)
• Pediatric Infectious Diseases Physicians' Preferences for Management of Clostridioides difficile Infection: An Emerging Infections Network Surve (Journal of the Pediatric Infectious Diseases Society)
• Antibiotic Therapy for Uncomplicated AcuteAppendicitis (JAMA)
• Fungal
• The Last of US Season 2 (YouTube)
• Persistence of Symptoms among Commercially Insured Patients with Coccidioidomycosis, United States, 2017–2023 (CDC: Emerging Infectious Diseases)
• Ophthalmologic evaluation and clinical outcome in candidemia: a seven-year retrospective multicenter cohort study (OFID)
• Parasitic
• Postinfectious Syndromes and Long-Term Sequelae after Giardia Infections (CDC: Emergining Infectious Diseases)
• Priced Out of Treatment: The Exorbitant Cost of Antiparasitic Drugs in the United States (OFID)
• Miscellaneous
• All About the AAP Recommended Immunization Schedule (healthychildren.org)
• Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics)
• Feeling the Vibes: An Investigation into Resident Antibiotic Prescribing Practices (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #98 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/1/26 – 1/14/26.

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• Viral
• Rhinovirus-Associated Lower Respiratory Tract Infection in Hospitalized Adult Patients: A Retrospective Cohort Study (JID)
• Demise of the Milwaukee Protocol for Rabies (CID)
• Reply to Willoughby on Demise of the Milwaukee Protocol for Rabies (CID)
• Bacterial
• Clinical Practice Guideline by Infectious Diseases Society of America (IDSA): 2025 Guideline on Management and Treatment of Complicated Urinary Tract Infections: Introduction and Methods (CID)
• Reassessing the 2023 International Society for Cardiovascular Infectious Diseases Duke clinical criteria for infective endocarditis: Impact of excluding fever and updating diagnostic definition (CID)
• The diagnostic accuracy of procalcitonin for community-acquired bacteremia: an updated systematic review and meta-analysis (CMI: Clincal Microbiology and Infection)
• Noninferiority of One HPV Vaccine Dose to TwoDoses (NEJM)
• About the wastewater program (Colorado: Department of Public & Environment)
• Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak — Colorado, August 2025 (CDC: MMWR)
• Notes from the Field: Retrospective Analysis of Wild-Type Measles Virus in Wastewater During a Measles Outbreak — Oregon, March 24–September 22, 2024 (CDC:MMWR)
• Fungal
• The Last of US Season 2 (YouTube)
• Candidozyma auris (formerly Candida auris): Resistant, long-lasting, and everywhere (CMI: Clincal Microbiology and Infection)
• Long-range air dispersal as an important source of environmental contamination in Candida auris clustering: possible infection control implication (Infection Control & Hospital Epidemiology)
• Parasitic
• Dermlite Dermatoscopes (dermatoscopes.com)
• Oral ivermectin versus 5% permethrin cream to treat children and adults with classic scabies: multicentre, assessor blinded, cluster randomised clinical trials (BMJ)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #97 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 12/18/25 – 12/31/25.

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• Viral
• Outcomes Related to Bacterial Co-Infection and Antibiotic Use in Adults Hospitalized With Respiratory Syncytial Virus Compared with Influenza (OFID)
• Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 (Annals of Internal Medicine)
• Bacterial
• GeoSentinel Analysis of Travelers' Diarrhea Antimicrobial Resistance Patterns (JAMA Open Network)
• Rapid direct disk diffusion testing for antibiotic resistance in urinary tract infections: a bacterial concentration-adjusted approach (Microbiology Spectrum)
• Impact of an Educational Leaflet About Asymptomatic Bacteriuria and Urinary Tract Infection on Antibiotic Preferences Among US Adults ≥65 Years: An Online Randomized Controlled Survey Experiment (OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Real-world Evaluation of Histoplasmosis Diagnosis and Treatment in Patients From a Michigan Health System (OFID)
• Parasitic
• Progress Toward Eradication of Dracunculiasis (Guinea Worm Disease) — Worldwide, January 2024–June 2025 (CDC: MMWR)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #96 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/4/25 – 12/17/25.

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• Viral
• Rabies Cluster Among Steer on a Dairy Farm — Minnesota, 2024 (CDC:MMWR)
• Incidence of community-acquired pneumonia and herpes zoster in people with HIV based on CD4-count and age in the current antiretroviral therapy era: a longitudinal cohort study (CID)
• Associations between antibiotic use and outcomes in patients hospitalized with community-acquired pneumonia and positive respiratory viral assays (CID)
• Bacterial
• Lactobacillus Bacteremia: A Challenging Condition for Pediatrician (Pediatric Infectious Disease Journal)
• Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis (NEJM)
• Zoliflodacin versus ceftriaxone plus azithromycin for treatment of uncomplicated urogenital gonorrhoea: an international, randomised, controlled, open-label, phase 3, non-inferiority clinical trial (LANCET)
• Fungal
• The Last of US Season 2 (YouTube)
• Compassionate Use of Olorofim for Invasive Mold Infections: A Nationwide Observational Study in France  (OFID)
• Parasitic
• Eliminating Guinea worm (LANCET: Infectious Disases)
• Balamuthia mandrillaris Encephalitis in a 12-Year-old Girl: Report of the First Case Diagnosed in Greece (Pediatric Infectious Disease Journal)
• A Prospective Cohort Longitudinal Study of Human Acute Babesiosis: Quality of Life and Severity of Symptoms Through 1-Year Follow-up (OFID)
• Body lice and scabies co-infestation among unsheltered migrants, refugees, and asylum seekers and the right to water and sanitation (PLoS Neglected Tropical Diseases)
• Miscellaneous
• H.U.S.T.L.E: A Consult Fitness Guide for Infectious Diseases Providers (CID)
• Seven alternatives to evidence based medical education: an exploration of how we actually teach (BMJ)
• What does a doctor look like?Asking AI (BMJ)
• The Receding Specialty of Infectious Diseases and Implications for U.S. Healthcare (OFID)
• Integrating a host biomarker with a large language model for diagnosis of lower respiratory tract infection (Nature Communications)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #95 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/20/25 – 12/3/25.

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• Viral
• Early low-dose dexamethasone is associated with shorter acute symptom duration in Chikungunya virus infection: a retrospective cohort study (BMC Infectious Diseases)
• Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM)
• Evidence to Action — Single-Dose HPV Vaccination and Cervical HPV Infection (NEJM)
• Daily Mosnodenvir as Dengue Prophylaxis in a Controlled Human InfectionModel (NEJM)
• Universal Hepatitis B Vaccination at Birth—Risks of Revising the recommendation (JAMA)
• Correlates of HIV-1 control after combination immunotherapy (Nature)
• Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 (CDC: MMWR)
• Cytomegalovirus-specific cell-mediated immunity for prediction of post-prophylaxis CMV disease in a phase 3 trial of letermovir vs valganciclovir prophylaxis in donor CMV-seropositive recipient CMV-seronegative kidney transplant recipients (CID)
• An Analysis of Cytomegalovirus-Specific Cell-Mediated Immunity in a Phase 3, Randomized, Placebo-Controlled Trial of Letermovir Prophylaxis in Cytomegalovirus-Seropositive Recipients of an Allogeneic Hematopoietic Cell Transplant (CID)
• Bacterial
• Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID)
• Lyme DiseaseIncidence in Massachusetts, 2012-2024 (JAMA: Open Network)
• Fungal
• The Last of US Season 2 (YouTube)
• Aspergillosis-Attributable Mortality in the United States: Analysis of Death CertificateData (CID)
• Oral itraconazole versus oral voriconazole for treatment-naive patients with chronic pulmonary aspergillosis in India (VICTOR-CPA trial): a single-centre, open-label, randomised, controlled, superiority trial (LANCET: Infectious Diseases)
• Parasitic
• Loa loa encephalopathy following treatment with benzimidazole derivatives: A systematic review (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #94 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/11/25 – 11/19/25.

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• Viral
• Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus (Science Translational Medicine)
• Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice (CID)
• Antimicrobial drug-resistant Neisseria gonorrhoeae (GC) infections in men using doxycycline postexposure prophylaxis. A substudy of the ANRS 174 DOXYVAC trial (CID)
• HIV Pre-exposure Prophylaxis Does Not Increase Gonorrhea and Chlamydia Incidence in Young Black and Hispanic Men who Have Sex With Men: An Observational Cohort Study (OFID)
• Bacterial
• Global and regional knowledge of antibiotic use and resistance among the general public: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection)
• Infant Botulism Outbreak Linked to Infant Formula, November 2025 (CDC: Botulism)
• Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA)
• Vitamin D deficiency at hospital admission with community-acquired pneumonia is associated with increased risk of mortality: A Prospective Cohort Study (OFID)
• Bat-Associated Hemotropic Mycoplasmas in Immunosuppressed Children, Spain, 2024 (Emerging Infectious Diseases)
• A Multicomponent Intervention to Improve Maternal Infection Outcomes (NEJM)
• Fungal
• The Last of US Season 2 (YouTube)
• Increasing Fluconazole Resistance in Candida parapsilosis: A 10-Year Analysis of Blood Culture Isolates at a US Reference Laboratory (2015–2024) (JID)
• British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update (LANCET: Infectious Diseases)
• In Vivo Evolution of Candida auris Multidrug Resistance in a Patient Receiving Antifungal Treatment (JID)
• Parasitic
• Implications of a fatal anaphylactic reaction occurring 4 hours after eating beef in a young man with IgE antibodies to galactose-α-1,3-galactose (JACI: Journal of Allergy and Clinical Immunology In practice)
• WHO recommends R21/Matrix-M vaccine for malaria prevention in updated advice on immunization (WHO)
• Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi (LANCET: Global Health)
• A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication? (PLoS Neglected Tropical Diseases)
• Miscellaneous
• IL12RB1 deficiency appearing in North America: expanding the clinical phenotypes (CID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #93 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/23/25 – 11/10/25.

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• Viral
• High Prevalence of Varicella Zoster Virus Infection among Persons with Suspect Mpox Cases during an Mpox Outbreak in Kenya, 2024 (ASTMH: AJTMH)
• Earlier initiation of treatment following HIV acquisition reduces non-AIDS-defining malignancy risk (CID)
• TWiV 1267: A cancer vaccine and an mpox treatment (MicrobeTV)
• Cancers Caused by HPV (CDC: Human Papillomavirus (HPV))
• Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of the National Cancer Institute)
• Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine—A Systematic Review (Viruses)
• ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP))
• HPV Vaccination Recommendations (CDC: Vaccines & Immunizations)
• Bacterial
• Consequences of Delaying Surgical Intervention in Patients with Native Joint Septic Arthritis (OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC): a multicentre, double-blind, randomised controlled trial (LANCET: Respiratory Medicine)
• Nasal Iodophor to Reduce Candidozyma auris Nasal Carriage in Nursing Home Residents (OFID)
• Epidemiology of Invasive Fungal Disease in Pediatric Heart Transplant Recipients (Journal of Pediatric Infectious Diseases Society)
• Mapping the Geographic Distribution of Dimorphic Mycoses Using a US Commercial Insurance Database (OFID)
• Genomic Dynamics of the Emergent Candida auris: Exploring Climate-dependentTrends (OFID)
• Parasitic
• Evaluation of a One Health public health program based on minimum inputs to control Taenia solium in Madagascar (PLoS Neglected Tropical Diseases)
• Transplacental Transfer of Lumefantrine, Mefloquine, and Piperaquine: A Comparison of Concentrations in Mothers, Neonates, and Cord Blood (CID)
• Miscellaneous
• Amplifying Our Voices: Fostering Advocacy in Infectious Diseases Fellowship(OFID)
• Plant-Based Diets and Climate Change, A Perspective for Infectious Disease Provider (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #92 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/9/25 – 10/22/25.

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• Viral
• Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study (CID)
• Resistance Analyses of Lenacapavir, Emtricitabine/Tenofovir Alafenamide and Emtricitabine/Tenofovir Disoproxil Fumarate in the PURPOSE 1 and 2 Studies (JID)
• Susceptibility of measles virus to WHO hand rubs, oral and surface disinfectants (OFID)
• Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID)
• The 2025 Centers for Disease Control and Prevention Non-Occupational HIV Post-Exposure Prophylaxis Guidelines (CID)
• Bacterial
• Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army (Current Biology)
• Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality (NEJM)
• Efficacy and safety of tedizolid in the treatment of acute bacterial skin and skin-structure infections (CMI: Clinical Microbiology and Infection)
• Zoonotic Escherichia coli and urinary tract infections in Southern California (mBio)
• Cefdinir Versus Cephalexin for the Treatment of Uncomplicated Urinary Tract Infections (OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus (Journal of Antimicrobial Chemotherapy)
• Parasitic
• Miscellaneous
• CARB Your Enthusiasm: An Ethics-Informed Analysis for Clinicians of the US National Action Plan for Combating Antibiotic-Resistant BacteriaCID)
• Infection Control in Carceral Facilities (CID)
• Infection Prevention and Control in Carceral Settings (CID)
• The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research)
• SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature)
• TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV)
• Infected With the Academic Bug (CID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #91 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 9/25/25 – 10/8/25.

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• Viral
• American Academy of Pediatrics
• Comparison of 2 Doses vs 1 Dose in the First Season Children Are Vaccinated Against Influenza(JAMA: Open Network)
• Flu and Children (CDC: Influenza (flu))
• Bacterial
• Performance of Different Versions of Duke Criteria in Diagnosing Infective Endocarditis in Patients With Intracardiac Prosthetic (OFID)
• 2023 Duke criteria on Infectious Disease (Puscast 28)
• Infective Endocarditis and Antimicrobial Timing: A Case for Delay? (OFID)
• Tularemia: A Storied History, An Ongoing Threat (CID)
• Tularemia Antimicrobial Treatment and Prophylaxis: CDC Recommendations for Naturally Acquired Infections and Bioterrorism Response — United States, 2025 (CDC: MMWR)
• Fungal
• The Last of US Season 2 (YouTube)
• Risk factors associated with progression to clinical Candida auris infection among adults with previous colonization—Florida, 2019–2023 (CID)
• Parasitic
• Public Health Response to the First Locally Acquired Malaria Outbreaks in the US in 20 Years (JAMA: Open Network)
• Miscellaneous
• Fever in sepsis revisited: Is a little heat what we need? (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #90 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/12/25 – 9/24/25.

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• Viral
• Crushed Bictegravir/Emtricitabine/Tenofovir Alafenamide (OFID)
• Tracking County-Level Measles Cases in the US (JAMA Nework)
• Tracking measles in US (Hopkins)
•  Pediatric influenza-associated encephalopathy and acute necrotizing encephalopathy (MMWR)
• Clinical recommendations for Lenacapivir (MMWR)
  Bacterial
• Primary oral vancomycin prophylaxis to stem an outbreak of Clostridioides difficile infection in intensive care patients (Antimicrob Steward Healthc Epidemiol)
• Clinical features and treatment strategies of Q fever spinal infection (OFID)
  Fungal
• Last of Us Season 2
• The Pain is in the Brain (J Inf Dis)
  Parasitic
• Chagas Disease, an Endemic Disease in the United States (MMWR)
• Fixed-dose ivermectin for Mass Drug Administration (PLoS NTD)
• Outbreak of eosinophilic meningitis caused by the rat lungworm (Angiostrongylus cantonensis) in South Brazil (Am J Trop Med Hyg)
• Human monoclonal antibody MAM01 for protection against malaria in adults in the USA (Lancet Inf Dis)
• Permethrin-Treated Baby Wraps for the Prevention of Malaria (NEJM)
  Miscellaneous
• Ambient Documentation Technology in Clinician Experience of Documentation Burden and Burnout (JAMA Network Open)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #89 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/18/25 – 9/11/25.

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• Viral
• Antibody Responses are Sustained 2 Years Post-Mpox Infection but not Following Modified Vaccinia Ankara–Bavarian Nordic Vaccination (OFID)
• Intestinal mucosal immune responses to novel oral poliovirus vaccine type 2 in healthy newborns (CID)
• Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza (NEJM)
• Fulminant Viral Myocarditis Associated with Thogotovirus (NEJM)
• Bacterial
• Risk factors for 30-Day mortality and the role of empirical therapy in Pseudomonas aeruginosa bloodstream infections(Infection)
• The Impact of a Nationwide Blood Culture Bottle Shortage in 2024 on Healthcare Facilities in the United States (CID)
• The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli(NPJ: antimicrobials and resistance)
• Preoperative Enterosignatures Predict Surgical Site Infections After Abdominal Surgery (OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Association between Duration of Candidemia and Clinical and Healthcare Resource Utilization Outcomes among Hospitalized Adult Patients with Candidemia Who Received Empiric Treatment with an Echinocandin Across United States Hospitals (CID)
• Updating the epidemiology of blastomycosis and histoplasmosis in the United States, using national electronic health record data, 2013–2023 (JID)
• Parasitic
• Stocking African catfish in Lake Victoria provides effective biocontrol of snail vectors of Schistosoma mansoni (PLoS Neglected Tropical Disease)
• Miscellaneous

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #88 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/19/25 – 8/27/25.

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• Viral
• Respiratory Syncytial Virus Immunization Coverage Among Infants Through Receipt of Nirsevimab Monoclonal Antibody or Maternal Vaccination (CDC: MMWR)
• Bictegravir, emtricitabine, and tenofovir alafenamide versus ritonavir-boosted protease inhibitor-based antiretroviral therapy in people with HIV and viral suppression on second-line therapy in Haiti: an open-label, randomised, non-inferiority trial (LANCET: HIV)
• Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial (CID)
• Bacterial
• Exposure to suppressive antibiotic therapy in women with recurrent urinary tract infections and severity of infections: a retrospective population-based cohort study (BMJ Open)
• Effectiveness and safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria: a systematic review and meta-analysis of randomized controlled trials (OFID)
• Epidemiological, temporal, and geographic trends of leptospirosis in the United States, 2014–2020 (PLoS Neglected Tropical Diseases)
• Performance of Tongue Swabs for Tuberculosis Diagnosis in Hospitalized Children Under 5 Years of Age (OFID)
• Fungal
• The Last of US Season 2 (YouTube)
• Towards shorter therapy for candidaemia: defining uncomplicated candidaemia in adults (LANCET: Infectious Diseases)
• Parasitic
• Outcomes of Military Blood Donors at Joint Base San Antonio with Reactive Trypanosoma cruzi Antibody Screening (OFID)
• Cutaneous acanthamoebiasis: Two Cases Highlighting Diverse Histopathologic Findings (Journal of Cutaneous Pathology)
• Miscellaneous
• Linezolid-related Optic Nerve Disorders: Insight from a Pharmacovigilance Analysis of the U.S. FDA Adverse Event Reporting System (OFID)
• Extreme variability in linezolid concentrations in the ICU: A case for routine therapeutic drug monitoring (American Journal of Health-System Pharmacy)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #87 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/31/25 – 8/18/25.

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• Viral
• Adjuvanted recombinant zoster vaccine is effective against herpes zoster ophthalmicus, and is associated with lower risk of acute myocardial infarction and stroke in adults aged ≥50 years (CID)
• Bacterial
• Dalbavancin for Treatment of Staphylococcus aureus Bacteremia (JAMA)
• Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumoni (OFID)
• The proportion of Treponema pallidum PCR-positive primary syphilis infections which are seronegative for syphilis (OFID)
• Cefixime versus benzathine penicillin G for the treatment of early syphilis (Journal of Antimicrobial Chemotherapy)
• Dalbavancin for Treatment of Staphylococcus aureus Bacteremia (JAMA)
• Fungal
• The Last of US Season 2 (YouTube)
• Parasitic
• Increasing Length of the Babesia Season in New England in the Climate Change Era (OFID)
• Ivermectin to Control Malaria (NEJM)
• Miscellaneous
• ACIP Recommendations Summary (CDC: Influenza)
• Relative effectiveness of high-dose versus standard-dose influenza vaccine against hospitalizations and mortality according to frailty score (JID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #86 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/22 – 8/1/25.

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• Viral
• Long-term clinical sequelae among Sudan ebolavirus disease survivors 2 years post-infection (BMC Medicine)
• Bacterial
• War on AMR: High MDR carriage rates among war-injured Ukrainian refugees (CMI: Clinical Microbiology and Infection)
• Oral washes and tongue swabs for Xpert MTB/RIF Ultra-based tuberculosis diagnosis in people with and without the ability to make sputum (CID)
• Fungal
• The Last of US Season 2 (YouTube)
• Progression from Candida auris Colonization Screening to Clinical Case Status, United States, 2016–2023 (CDC: Emerging Infectious Diseases)
• Regional Emergence of Candida auris in Chicago and Lessons Learned From Intensive Follow-up at 1 Ventilator-Capable Skilled Nursing Facility (CID)
• Infection Control Guidance: Candida auris (CDC: Candida auris)
• Twice Weekly Sulfamethoxazole/Trimethoprim for Pneumocystis jiroveci Pneumonia Prophylaxis in Lung Transplant Recipients(Transplant Infectious Disease)
• Parasitic
• Toxoplasma gondii infection of neurons alters the production and content of extracellular vesicles directing astrocyte phenotype and contributing to the loss of GLT-1 in the infected brain (PLoS Pathogens)
• Baylisascariasis (Raccoon Roundworm Infection) in Two Unrelated Children  (CDC: MMWR)
• Miscellaneous
• A Review of Alpha Gal Syndrome for the Infectious Diseases Practitioner (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #85 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/3 – 7/21/25.

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• Viral
• Elimination of HIV Reservoirs Harboring Intact Proviruses (JID)
  Bacterial
• Expansion of tetM-Carrying Neisseria gonorrhoeae in the United States, 2018–2024 (NEJM)
• Study hints doxyPEP use coincides with rise in tetracycline-resistant gonorrhea in US (CIDRAP)
• Potential Impact of Doxycycline Post-Exposure Prophylaxis on Tetracycline Resistance in Neisseria gonorrhoeae and Colonization With Tetracycline-Resistant Staphylococcus aureus and Group A Streptococcus (CID)
• Methenamine hippurate asprophylaxis for recurrent urinary tract infections in older women – a triple-blind, randomised, placebo-controlled, phase IV trial (ImpresU). (CMI: Clinical Microbiology and Infection)
• Diagnosis and Management ofCommunity-acquired Pneumonia(American Journal of Respiratory and Critical Care Medicine)
• Complicated Urinary Tract Infections (cUTI): Clinical Guidelines for Treatment and Management (IDSA)
• The impact of an intervention to increase follow-up blood cultures for patients with Staphylococcus aureus bacteriuria (Antimicrobial Stewardship & Healthcare Epidemiology)
  Fungal
• The Last of US Season 2 (YouTube)
• Candida auris Containment Responses in Health Care Facilities that Provide Hemodialysis Services (CDC: MMWR)
• Candidozyma auris: an emerging threat (Reflections on Infectious Prevention and Control)
• Effects of postoperative antifungal therapy on the recurrence of Aspergillus infection after pulmonary aspergilloma resection (BMC Infectious Diseases)
• Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022: a genomic and phenotypic study (LANCET: Microbe)
• Large language models and their performance for the diagnosis of histoplasmosis (PLoS Neglected Tropical Diseases)
  Parasitic
• Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA (PLoS Neglected Tropical Diseases)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #84 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/17 – 7/2/25.

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• Viral
• Clinical Outcomes and Perspectives of People With Human Immunodeficiency Virus Type 1 Twelve Months After Initiation of Long-acting Cabotegravir and Rilpivirine in an Observational Real-world US Study (BEYOND)(CID)
• Healthcare Provider Knowledge of West Nile Virus Diagnostic Testing—United States, 2022 (OFID)
• Bacterial
• Risk and Distribution of Metastatic Infections by Primary Infection Focus in Staphylococcus aureus Bacteremia (OFID)
• Clinical management of Clostridioides difficile infection with faecal microbiota transplantation (eClinicalMedicine)
• Clinical Practice Guidelines for the Management of Clostridioides difficile Infection in Adults (IDSA)
• Clinician Management Preferences for Clostridioides difficile Infection in Adults (OFID)
• Donor-Derived Tuberculosis In Three Solid Organ Transplant Recipients From The Same Donor (OFID)
• Septic Arthritis and Osteomyelitis in Finger Caused by Mycoplasma phocimorsus from Brown Bear, Alaska, USA (CDC: Emerging Infectious Diseases)
• Foodborne Botulism Outbreak After Consumption of Home-Canned Cactus (Nopales) (CDC: MMWR)
• One-Stage Revision Total Hip Arthroplasty for Polymicrobial Periprosthetic Joint Infection Leads to High Reinfection Rates (Journal of Arthroplasty)
• 4,000-year-old Mycobacterium lepromatosis genomes from Chile reveal long establishment of Hansen's disease in the Americas (Nature Ecology & Evolution)
• Fungal
• The Last of US Season 2 (YouTube)
• Outcome Predictors of Candida Prosthetic Joint Infection (OFID)
• Parasitic
• Miscellaneous
• Ten Practical Tips for a Successful Presentation at ID clinical case conference (OFID)
• Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030 (LANCET)
• Comparison of Periodic In-Person ID Care to Daily Tele-ID Care at a Community Hospital (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #83 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/5 – 6/18/25.

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• Viral
• Premature Demise of the Milwaukee Protocol (CID)
• West Nile Virus and Other Nationally Notifiable Arboviral Diseases — United States, 2023 (CDC: MMWR)
• Investigation of associations between the neonatal gut microbiota and severe viral lower respiratory tract infections in the first 2 years of life (LANCET: Microbe)
• Right blend of gut microbiota could avert hospitalization forviral respiratory infection in babies (CIDRAP)
• Clinical management and infection prevention and control for mpox: living guideline, May 2025 (World Health Organization)
• Bacterial
• Corynebacterium diphtheriaeOutbreak in Migrant Populations in Europe (NEJM)
• Weekly Oral Cycling Antibiotic Treatment: A New Antibioprophylaxis Regimen for Recurrent UTIs (CID)
• Fungal
• The Last of US Season 2 (YouTube)
• Estimated Burden of Coccidioidomycosis (JAMA)
• Antifungal therapy in Candida infective endocarditis: a comparison of echinocandins and other treatment regimens in a nation-wide cohort study (CID)
• Parasitic Does schistosome infection affect behavior through the gut-brain axis? (PLoS Neglected Tropical Diseases)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #82 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/22 – 6/4/25.

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• Viral
• Estimated Current and Future Congenital Rubella Syndrome Incidence with and Without Rubella Vaccine Introduction — 19 Countries, 2019–2055 (CDC: MMWR)
• HIV-Superinfection in Kidney Transplant Recipients with HIV who Received Organs from Donors with HIV (JID)
• Respiratory syncytial virus: an under-recognized healthcare-associated infection (Infection Control and Hospital Epidemiology)
• Bacterial
• Francisella tularensis Subspecies holarctica in Stranded Beluga Whales, Cook Inlet, Alaska, USA (CDC: Emerging Infectious Diseases)
• Long-term effects of azithromycin mass administration to reduce childhood mortality on Streptococcus pneumoniae antimicrobial resistance (LANCET: Infectious Diseases)
• Reducing inappropriate antibiotic use in febrile neutropenia in hematology patients through the implementation of an antibiotic de-escalation protocol (Infection Control and Hospital Epidemiology)
• Optimizing cefazolin dosing for central nervous system infections: insights from population pharmacokinetics and Monte Carlo simulations (Antimicrobial Agents and Chemotherapy)
• Fungal
• The Last of US Season 2 (YouTube)
• Histoplasma antigenuria prevalence in patients with advanced HIV disease in Côted'Ivoire (CID)
• Interferon-γ therapy in patients with refractory disseminated coccidioidomycosis(CID)
• Practical Guidance for Clinical Microbiology Laboratories: Antibody and antigen detection methods for dimorphic fungal infections (Clinical Microbiology Reviews)
• Parasitic
• Notes from the Field: Primary Amebic Meningoencephalitis Associated with Nasal Irrigation Using Water from a Recreational Vehicle — Texas, 2024 (CDC: MMWR)
• Further Evidence for Plausible Transmission of Fishborne Trematodiases in the United States: Game Fish Carry Human-Infectious Trematodes and Are Eaten Raw (JID)
• Miscellaneous
• A pilot study of coughing into the shirt to disrupt respiratory pathogen transmission (International Journal Of Emergency Medicine)
• Applying new compound to bed nets targets malaria parasites, not mosquitoes (CIDRAP)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #81 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 5/8/25 – 5/21/25.

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• Viral
• Tecovirimat for Clade I MPXV Infection in the Democratic Republic of Congo (NEJM)
• Remdesivir associated with reduced mortality in hospitalized COVID-19 patients (BMC Infectious Diseases)
• Real-world evidence shows remdesivir tied to less death in hospitalized COVID patients (CIDRAP)
• Impact of most promising Ebola therapies on survival (Virology Journal)
• Bacterial
• Comparative effectiveness of azithromycin versus doxycycline in hospitalized patients with community acquired pneumonia treated with beta-lactams (CID)
• Diet and Risk for Incident Diverticulitis in Women (Annals of Internal Medicine)
• The Dynamics of QuantiFERON-TB Gold In-Tube Conversion and Reversion in a Cohort of South African Adolescents(American Journal of Respiratory and Critical Care Medicine)
• BCG Revaccination for the Prevention of Mycobacterium tuberculosis Infection(NEJM)
• The Impact of Diet on Clostridioides difficile Infection (JID)
• Cefazolin versus Antistaphylococcal Penicillins for the Treatment of Methicillin-Susceptible Staphylococcusaureus Bacteremia (CMI: Clinical Microbiology and Infection)
• Fungal
• The Last of US Season 2 (YouTube)
• Candida auris is emerging as a prevalent urinary pathogen (PLoS Pathgoens
• A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite–CerS6–ceramide axis (Science)
• Outcome predictors of Candida prosthetic joint infections (OFID)
• Cave-Associated Histoplasmosis Outbreak Among Travelers Returning from Costa Rica — Georgia, Texas, and Washington, December 2024–January 2025 (CDC: MMWR)
• Parasitic
• COPEG 25th Anniversary (US Embassy in Panama)
• USDA suspends southern border livestock imports over New World screwworm threat(CIDRAP)
• Moxidectin combination therapies for lymphatic filariasis (LANCET: Infectious Diseases

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #80 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/24/25 – 5/7/25.

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• Viral
• Incidence and Timing of Epstein–Barr Virus Whole Blood DNAemia in Epstein–Barr Virus-Mismatched Adult and Pediatric Solid Organ Transplant Recipients (Transplant Infectious Disease)
• Infant Respiratory Syncytial Virus Immunization Coverage in the Vaccine Safety Datalink: 2023–2024 (American Academy of Pediatrics)
• Impact of Nirsevimab on RSV and Non-RSV Severe Respiratory Infections in Hospitalized Infants (Influenza and other respiratory viruses)
• Hospital admissions of respiratory infections in infants plungewith nirsevimab RSV antibody (CIDRAP)
• Time to antiviral treatment in mild–moderate COVID-19 in the emergency department (Internal and Emergency Medicine)
• Delays in COVID antiviral receipt raised risk of poor outcomes after ED visits by 18%, data suggest (CIDRAP)
• Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV (MMWR)
• Bacterial
• Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis (LANCET: Regional Health)
• Bridging to transplant: TDM-Guided Outpatient Dalbavancin Therapy in Chronic Granulomatous Disease with deep-seeded Inoperable Abscesses over 11 Months (OFID)
• Nitrites for Urinary Tract Infection—Time to Say Goodbye? (JAMA: Internal Medicine)
• Fungal
• The Last of US Season 2 (YouTube)
• High Mortality and Associated Risk Factors in Kidney Transplant Recipients with Cryptococcosis – A Nationwide Cohort Study Over a Decade Using USRDS Data (OFID)
• Use of Dog Serologic Data for Improved Understanding of Coccidioidomycosis (JID)
• Parasitic
• Performance of a novel P. falciparum rapid diagnostic test in areas of widespread hrp2/3 gene deletion (CID)
• Prevalence of Anopheles stephensi in the Horn of Africa: a systematic review and meta-analysis (BMC Infectious Diseases)
• Raising awareness of Demodex mites: a neglected cause of skin disease (Infection)
• Miscellaneous
• Scientific Integrity Under Threat: The Role of the IDSA, PIDS, and SHEA Journals in an Evolving Political Landscape (CID)
• Reasoning on Rounds Volume 2: a Framework for Teaching Management Reasoning in the Inpatient Setting (Journal of General Internal Medicine)
• Billing for and documentation of provider-to-provider interprofessional consults in infectious diseases (Journal of the Pediatric Infectious Diseases Society)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #79 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/10/25 – 4/23/25.

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• Viral
• An ancient Epstein-Barr virus genome recovered from a museum penis gourd from Papua (JID)
• Patterns of Decline in Measles, Mumps, and Rubella Neutralizing Antibodies and Protection Levels Through 10 Years After a Second and Third Dose of MMR Vaccine (OFID)
• Tecovirimat for Clade I MPXV Infection in the Democratic Republic of Congo(NEJM)
• Bacterial
• Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay(Science Translational Medicine)
• New handheld device can diagnose TB without a lab in under an hour, its developers say(CIDRAP)
• Maternal mastitis and streptococcal toxic shock syndrome risk from breastfeeding children with scarlet fever (LANCET: Infectious Diseases)
• Risk Factors for Mortality Among Older Adults with Hospital-Acquired Bloodstream Infections in the Intensive Care Unit(Infectious Diseases and Therapy)
• Bacteremia in Pediatric Solid Organ Transplant Recipients within 1 Year of Transplant(Transplant Infectious Disease)
• Oral gepotidacin for the treatment of uncomplicated urogenital gonorrhoea (EAGLE-1) (LANCET)
• Consequences of Climate Change on the Emergence of Pathogenic, Environmentally Acquired Nontuberculous Mycobacteria (OFID)
• Addition of Macrolide Antibiotics for Hospital Treatment of Community-Acquired Pneumonia (JID)
• Point-of-Care Testingby Multiplex-PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation(Transplant Infectious Disease)
• Fungal
• The Last of US Season 2 (YouTube)
• Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome (Science Advances)
• Use of Dog Serologic Data for Improved Understanding of Coccidioidomycosis (JID)
• Parasitic
• Uganda launches largest malaria vaccine introduction to date(WHO: Uganda)
• Long-term follow-up of individuals with Chagas disease treated with posaconazole and benznidazole in a non-endemic region(CMI: Clinical Microbiology and Infection)
• Miscellaneous
• Monoclonal Antibodies From Children With Acute Kawasaki Disease Identify a Common Antigenic Target in Fatal Cases Over 5 Decades (Laboratory Investigation)
• Screwworm Cochliomyia hominivorax (Facebook)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #78 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/27/25 – 4/9/25.

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• Viral
• Demise of the Milwaukee protocol for rabies (CID)
• A natural experiment on the effect of herpes zoster vaccination on dementia (Nature)
• Taking a shot at dementia(microbeTV: TWiV)
• Recommendations from the 10th European Conference on Infections in Leukaemia for the management of cytomegalovirusin patients after allogeneic haematopoietic cell transplantation and other T-cell-engaging therapies (LANCET: Infectious Diseases)
• Epstein-Barr virus exposure precedes Crohn`s disease development (Gastroenterology aga)
• Bacterial
• Blujepa (gepotidacin) approved by US FDA for treatment of uncomplicated urinary tract infections (uUTIs) in female adults and paediatric patients 12 years of age and older (GSK)
• GSK wins FDA nod for first oral UTI antibiotic in almost 30 years(BioSpace)
• Efficacy and safety of individualised versus standard 10-day antibiotic treatment in children with febrile urinary tract infection (INDI-UTI): a pragmatic, open-label, multicentre, randomised, controlled, non-inferiority trial in Denmark (LANCET: Infectious Diseases)
• Frequency and severity of Myasthenia Gravis exacerbations associated with the use of ciprofloxacin, levofloxacin, and azithromycin (Muscle & Nerve)
• The cost of blood cultures: a barrier to diagnosis in low-income and middle-income countries
• (LANCET: Microbe)
• Rethinking blood culture (LANCET: Microbe)
• Trends in Anaplasmosis Over the Past Decade: A Review of Clinical Features, Laboratory Data and Outcomes(CID)
• Fungal
• The Last of US Season 2 (YouTube)
• Cracks in the curriculum: the hidden deficiencies in fungal disease coverage in medical books (OFID)
• Kazachstania slooffiae fungemia: a case report and literature review on an emerging opportunistic pathogen in humans (OFID)
• Plasma microbial cell-free DNS metagenomic sequencing for diagnosis of invasive fungal diseases among high risk outpatient and inpatient immunocompromised hosts (CID)
• Parasitic
• Fatal Case of Splash Pad–Associated Naegleria fowleri Meningoencephalitis — Pulaski County, Arkansas, September 2023 (CDC: MMWR)
• Notes from the Field: Fatal Acanthamoeba Encephalitis in a patient who regularly used tap water in an electronic nasal irrigation device and a continuous positive airway pressure machine at home — new Mexico, 2023 (CDC: MMWR)
• Malaria (NEJM)
• Miscellaneous
• FDA grants marketing authorization of first home test for chlamydia, gonorrhea and trichomoniasis (FDA)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #77 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/13/25 – 3/26/25.

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• Viral
• Food is medicine for human immunodeficiency virus: improved health and hospitalizations in the changing health through food support (chefs-hiv) pragmatic randomized trial (JID)
• The epidemiology and burden of human parainfluenza virus hospitalizations in u.s. children (Journal of the Pediatric Infectious Diseases Society)
• Bacterial
• Epidemiology and outcomes of bloodstream infections in patients in a burns intensive care unit: an eight-year retrospective study(OFID)
• Prophylactic vancomycin in the primary prevention of clostridium difficile in allogeneic stem cell transplant(Transplant Infectious Disease)
• Incidence of scrub typhus in rural south India (NEJM)
• Antibiotic treatment for 7 versus 14 days in patients with bloodstream infections(NEJM)
• Blood Culture–Negative Endocarditis(Journal of the American Heart Association)
• Brucella suis Infection in Cardiac Implantable Device of Man Exposed to Feral Swine Meat, Florida, USA (CDC Emerging Infectious Diseases)
• Hyperbilirubinemia at hospitalization predicts nosocomial infection in decompensated cirrhosis (Hepatology Communicatons)
• Fungal
• The Last of US Season 2 (YouTube)
• Fungal Infections in People Who Use Drugs (OFID)
• IDSA 2025 guideline update on the treatment of asymptomatic histoplasma pulmonary nodules (histoplasmomas) and mild or moderate acute pulmonary histoplasmosis in adults, children, and pregnant people(IDSA: Infectisous Disease Society of America)
• Changing trends in the sources and volumes of clinical cultures with Candida auris at a large health system, 2019-2023 (American Journal of Infection Control)
• Diagnostic test accuracy of the Fungitell serum (1→3)-β-D-glucan assay for the diagnosis of Pneumocystis jirovecii pneumonia: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection)
• Parasitic
• Impact of Strongyloides stercoralis Coinfection on Disease Severity and Treatment Outcomes in Pulmonary Tuberculosis (OFID)
• Hematology thin smears perform equally to parasitology thick and thin blood smears for the diagnosis of Plasmodium and Babesia infections in a low prevalence setting (Journal of Clinical Microbiology)
• Notes from the Field: Rhodesiense Human African Trypanosomiasis (Sleeping Sickness) in a Traveler Returning from Zimbabwe — United States, August 2024 (CDC: MMWR)
• Miscellaneous
• The history of phage therapy LANCET: Infectious Diseases)
• Silence=death redux: infectious diseases, public health, and the imperative to resist (CID)
• Silence = Death, 1990(David Wojnarowicz Foundation)
• SILENCE=DEATH (B200KLYN Museaum)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #76 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/27/25 – 3/12/25.

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• Viral
• Trends in respiratory pathogen testing at us children's hospitals (JAMA Network)
• Changes in respiratory viral testing before and after the covid-19 pandemic(JAMA Network)
• Expanding measles outbreak in the United States and guidance for the upcoming travel season (CDC Emergerncy Preparedness and Response)
• Measles cases and outbreaks (CDC Measles (Rubeola))
• Facts and myths about measles (LANCET: Infectious Diseases)
• Protective effects of recombinant zoster vaccine and antiviral therapy against cardiovascular disease following herpes zoster infection (JID)
• Chikungunya vaccine information for healthcare providers (CDC Chikungunya Virus)
• Factors to assess when considering use of chikungunya vaccine(CDC)
• Bacterial
• Should patients hospitalized forcommunity-acquired pneumonia be treated with additional antimicrobial agents directed against anaerobes? (American Journal of Therapeutics)
• Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy(Blood)
• Effectiveness of ampicillin/sulbactam versus ceftriaxone for the initial treatment of community-acquired pneumonia in older adults: a target trial emulation study(OFID)
• Male-partner treatment to prevent recurrence of bacterial vaginosis(NEJM)
• Fungal
• The Last of US Season 2 (YouTube)
• Activity of rezafungin against echinocandin non–wild type candida glabrata clinical isolates from a global surveillance program (OFID)
• Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study  (Intensive Care Medicine)
• Parasitic
• Human alveolar echinococcosis – global, regional and national annual incidence and prevalence rates (CMI: Clinical Microbiology and Infection)
• Dust to Diagnosis – with MSGERC (FEBRILE)
• The clinical picture caused by Fasciola gigantica: Analysis of 3,250 patients along the 1995–2019 countrywide spread in Vietnam (OFID)
• Miscellaneous
• Reprint of: From medical editors: a call to the global infectious diseases and clinical microbiology community (CMI: Clinical Microbiology and Infection)
• A hot topic: A climate-focused track for infectious disease fellowship (OFID)
• Are we being gaslit? A primer for recognizing corporate jargon to overcome gaslighting for the infectious disease workforce (CID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #75 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/13/25 – 2/26/25.

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• Viral
• VIMKUNYA (FDA)
• Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19(BMC Infectious Diseases)
• Measles (Texas Health and Human Services)
• 2025 Measles outbreak guidelines (New Mexico Health)
• BTN: Beyond the Noise with Paul Offit (microbeTV)
• Rubeola response (febrile)
• Timing of influenza antiviral therapy and risk of death in adults hospitalized with influenza-associated pneumonia, influenza hospitalization surveillance network (FluSurv-NET), 2012–2019 (CID)
• Mother-child dyads living with HIV in the Western Cape, South Africa: undetectable = undetectable? (Journal of the International AIDS Society)
• Early impacts of the PEPFAR stop-work order: a rapid assessment(Journal of the International AIDS Society)
• Prevalence, clinical management, and outcomes of adults hospitalised with endemic arbovirus illness in southeast Europe (MERMAIDS-ARBO): a prospective observational study (LANCET: Infectious Diseases)
• Bacterial
• Effects of extended anaerobic antibiotic coverage on anaerobic bloodstream infection: A multisite retrospective stud (International Journal of Infectious Diseases)
• The effectiveness of newer Beta-Lactams for the treatment of antimicrobial-resistant gram-negative meningitis (CID)
• Treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children: a aeta-analysis of macrolides versus tetracycline (The Pediatric Infectious Disease Journal)
• Fungal
• The Last of US Season 2 (YouTube)
• Concordance of noninvasive plasma cell-free DNA With invasive diagnostics for diagnosis of invasive fungal disease (CID)
• Invasive fungal infections in patients with liver disease: immunological and clinical considerations for the intensive care unit(Intensive Care Medicine)
• Parasitic
• Epidemiologic Investigation of Protozoa and soil-transmitted helminths in Starr County, Texas (American J Trop Med and Hyg)
• Post-artesunate delayed hemolysis in African children with severe malaria: incidence, medical impact and prevention (CID)
• Miscellaneous
• Telehealth (Medicare.gov)
• Public comment: IDSA guideline on management and treatment of complicated urinary tract infections (IDSA)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #74 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/30/25 – 2/12/25.

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• Viral
• Global Impact of mass vaccination campaigns on circulating type 2 vaccine-derived poliovirus outbreaks (JID)
• Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19 (BMC Infectious Diseases)
• Oseltamivir reduces 30-Day mortality in older adults with Influenza (OFID)
• Bacterial
• Predicting benefit from adjuvant therapy with corticosteroids in community-acquired pneumonia (LANCET Respiratory Medicine)
• Rethinking antibiotic prophylaxis for spontaneous bacterial peritonitis in patients with cirrhosis (CID)
• Determining the optimal antibiotic duration for skin and soft tissue infections (Current Opinion in Infectious Diseases)
• The stealth and potentially fatal nature of Kingella kingae outbreaks in daycare facilities (OFID)
• Piperacillin/tazobactam vs. cefepime or carbapenems for the treatment of bloodstream infections due to bacteria producing chromosomal AmpC beta-lactamase (Infection)
• Is systemic dissemination of BCG following neonatal vaccination required for protection against Mycobacterium tuberculosis? (JID)
• Risk of aortic aneurysm or dissection following use of fluoroquinolones: a retrospective multinational network cohort study (eClinical Medicine)
• Fungal
• The Last of US Season 2 (YouTube)
• Developing mRNA lipid nanoparticle vaccine effective for cryptococcosisin a murine model (Vaccines)
• The araneopathogenic genus Gibellula (Cordycipitaceae: Hypocreales) in the British Isles, including a new zombie species on orb-weaving cave spiders (Metainae: Tetragnathidae) (Fungal Systematics and Evolution)
• Sensitivity of Coccidioides serologic tests among culture-proven coccidioidomycosis patients with hematological malignancy compared to a matched immunocompetent cohort (Medical Mycology)
• Parasitic
• New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine (LANCET: Infectious Diseases)
• Miscellaneous
• Remote practice of infectious diseases through telemedicine (OFID)
• Telemedicine offers solutions for the rural disparities in infectious disease (ID) care delivery (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #73 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/16/25 – 1/29/25.

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• Viral
• AGA clinical practice guideline on the prevention and treatment of hepatitis B virus reactivation (Gastroenterology)
• Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients (Nature Communications)
• Insect-specific RNA viruses detection in Field-Caught Aedes aegypti mosquitoes from Argentina using NGS technology (PLoS Neglected Tropical Diseases)
• Bacterial
• Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis (NEJM)
• Impact of antibiotic treatment and predictors for subsequent infections in multidrug-resistant Pseudomonas aeruginosa catheter-associated asymptomatic bacteriuria (American Journal of Infection Control)
• Identification of the skip phenomenon among patients With Staphylococcus lugdunensis infective endocarditis (OFID)
• Emergence of infective endocarditis due to Serratia spp. (OFID)
• Reduction of vancomycin-associated acute kidney injury with montelukast (JID)
• Fungal
• The Last of US Season 2 (YouTube)
• Pulmonary co-infection of Pneumocystis jirovecii and Aspergillus species (OFID)
• Impact of fluconazoleon outcomes of patients with primary pulmonary coccidioidomycosis (CID)
• Parasitic
• Comparative outcomes of Babesiosis in immunocompromised and non-immunocompromised hosts (CID)
• Miscellaneous
• Hidradenitis suppurativa (LANCET)
• A severe case associated with mixed infections of Pasteurella multocida, Bacteroides pyogenes and Fusobacterium necrophorum due to a snow leopard bite (CMI: Clinical Microbiology and Infection)
• INSIDE-OUT: Introduction of speakers at IDWeek events (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #72 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/2/25 – 1/15/25.

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• Viral
• Human infection with a novel tickborne Orthonairovirus species in China(NEJM)
• Antiviral medications for treatment ofnonsevere influenza(JAMA Network: JAMA Internal Medicine)
•  Xofluza (GoodRx)
• NoroSTATData Table (CDC Norovirus)
• The discovery of the 27-nm Norwalk virus: an historic perspective (JID)
• Why the "Ferrari of viruses" is surging through the northern hemisphere (Science)
• Bacterial
• Beta-lactams toxicity in the intensive care unit: an underestimatedcollateral damage?
• (Microorganims)
• What is the most effective antibiotic monotherapy for severe Pseudomonas aeruginosa infection? (CMI: Clinical Microbiology and Infection)
• Doxycycline postexposure prophylaxis and bacterial sexually tansmitted infections among individuals using HIV preexposure prophylaxis(JAMA Network: JAMA Internal Medicine)
• Fungal
• The Last of US Season 2 (YouTube)
• Epidemiology and prognostic factors associated with mold-positive blood cultures: 10-year data From a french prospective surveillance program (2012–2022) (CID)
• Parasitic
• Safety and efficacy of immunization with a late-liver-stage attenuated malaria parasite
• (NEJM)
• Dr. Glaucomflecken explains: late-liver-stage attenuated malaria vaccine (YouTube)
• Dr. Glaucomflecken X NEJM (YouTube)
• Albendazole–ivermectin co-formulation for the treatment of Trichuris trichiura and other soil-transmitted helminths: a randomised phase 2/3 trial (LANCET: Infectious Diseases)
• Miscellaneous
• A comparison of peripherally insertedcentral catheter materials(NEJM)
• Considering Islamic frameworks to infectious disease prevention (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #71 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/19/24 – 1/1/25.

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• Viral
• Routine detection of viruses through metagenomics: where do we stand? (ASTMH)
• Rapid selection of HIV-2 capsid mutations in salvage therapy with Lenacapavir-containing regime (CID)
• Bacterial
• Ancient genomes reveal a deep history of treponemal disease in the Americas (Nature)
• The utility of Interferon-γ release assays in the diagnosis of tuberculosis in patients With cancer(Transplant Infectious Disease)
• A meta-analysis of Levofloxacin for contacts of multidrug-resistant tuberculosis (NEJM Evidence)
• Tularemia— United States, 2011–2022 (CDC: MMWR)
• Incorporating incubation period distributions to precisely estimate the association between rainfall and Legionella infection (JID)
• Fungal
• The Last of US Season 2 (YouTube)
• Candida albicans recovered from persistent candidemia exhibit enhanced virulence traits (JID)
• Mapping the geographic distribution of dimorphic mycoses using a U.S. commercial insurance database (OFID)
• Comparative efficacy and safety of treatment regimens for Pneumocystis jirovecii pneumonia in people living with HIV – A systematic review and network meta-analysis of randomized controlled trials (CMI: Clinical Microbiology and Infection)
• Outbreak of Blastomycosis Among Paper Mill Workers — Michigan, November 2022–May 2023 (CDC: MMWR)
• Parasitic
• Acanthamoeba Infection in a hematopoietic cell transplant recipient: challenges in diagnosis, management, and source identification (Transplant Infectious Disease)
• Congenital toxoplasmosis: Fewer clinical signs at 3 years of age over the last 15 years but stable risk of materno-fetal transmission (CID)
• Miscellaneous
• Detection of prions in wild pigs (Sus scrofa) from areas with reported chronic wasting disease cases, United States (CDC Emerging Infectious Diseases)
• Addition of macrolide antibiotics for hospital treatment of community-acquired pneumonia (JID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #70 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/5/24 – 12/18/24.

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• Viral
• Epidemiology of Dengue— Puerto Rico, 2010–2024(CDC MMWR)
• Takeda Announces Voluntary Withdrawal of U.S. Biologics License Application (BLA) for Dengue Vaccine Candidate TAK-003(Takeda)
•  Global health and economic burden of chikungunya from 2011 to 2020 (BMJ Global Health)
• Bacterial
• Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis (JAMA Network)
• Say it ain't Steno: a microbiology nudge comment leads to less treatment of Stenotrophomonas maltophilia respiratory colonization(Infection Control & Hospital Epidemiology)
• Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults(JAMA Network)
• Epidemiology and Outcomes of Antibiotic De-escalation in Patients with Suspected Sepsis in US Hospitals (CID)
• Effectiveness of ceftazidime–avibactam versus ceftolozane–tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the USA (CACTUS): a multicentre, retrospective, observational study (LANCET Infectious Diseases)
• Bedaquiline Monotherapy for Multibacillary Leprosy (NEJM)
• Fungal
• The Last of US Season 2 (YouTube)
• Histoplasmosis Associated With Bat Guano Exposure in Cannabis Grower (OFID)
• Parasitic
• TWiV 1175: A hitchiker's guide to virology(microbeTV)
• Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts (Nature Microbiology)
• Neurocysticercosis school outbreak in Belgium (LANCET)
• Miscellaneous
• Maintenance of Certification: Is a Knowledge-Based Assessment Really Necessary? (CID)
• Living happily ever after? The hidden health risks of Disney princesses (BMJ)
• How to transport a polar bear, and other idiosyncrasies in providing emergency medical services in the Arctic (BMJ)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #69 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 11/21 – 12/4/24.

Host: Sara Dong

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• Viral
• Antiretroviral Drugs for Treatment and Prevention of HIV in Adults(JAMA Network)
• Human Parvovirus B19 Infections Among Pregnant Persons — Minnesota, January–September 2024 (CDC MMWR)
• Maribavir for refractory cytomegalovirus infection (with or without resistance) in solid organ transplant recipients (Journal of Heart and Lung Transplantation)
• Bacterial
• Choosing Wisely: Effectiveness and Safety of Antibiotic Prophylaxis in Close Contacts of InvasiveGroup A Streptococci Infection (CID)
• Resurgence of pediatric Mycoplasma pneumoniae infections in Southeast Texas, Nov 2023-June 2024 (Journal of Pediatrics Infectious Diseases Society)
• Fungal
• The Last of US Season 2 (YouTube)
• Alternative Pneumocystis Pneumonia Prophylaxis in Solid Organ Transplants(Transplant Infectious Disease)
• Mortality in chronic pulmonary aspergillosis: a systematic review and individual patient data meta-analysis (LANCET: Infectious Diseases)
• Parasitic
• Waterborne Disease Outbreaks Associated with Splash Pads — United States, 1997–2022
•  (CDC MMWR)
• Miscellaneous
• Skin Color Representation in Infectious Disease Textbooks (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.

On episode #68 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 11/7 – 11/20/24.

Host: Daniel Griffin and Sara Dong

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• Viral
• Comparative Emergence of Maribavir and Ganciclovir Resistance in a Randomized Phase 3 Clinical Trial for Treatment of Cytomegalovirus Infection (JID)
• Yellow fever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis (LANCET Microbe)
• Serological evidence of natural exposure to rabies in rural populations in Gabon (PLoS Neglecgted Tropical Diseases)
• Bacterial
• Azithromycin Exposure in a 10-Day Window of Myocardial Infarction and Short- and Long-Term Outcomes (JACC Advances)
• Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (NEJM)
• The Long and Winding Road: Three-year Mortality Following Prescription of Multi-drug Antibiotic Treatment for Mycobacterium avium complex Pulmonary Disease in United States Medicare Beneficiaries with Bronchiectasis (OFID)
• Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis (CID)
• Carbapenem-resistant Enterobacteriales in solid organ transplant recipients (American Journal of Transplantation)
• Fungal
• The Last of US Season 2 (YouTube)
• Adaptation of Candida albicans to specific host environments by gain-of-function mutations in transcription factors(PLoS Pathogens)
• Diagnostic Test Accuracy of the Fungitell Serum (1→3)-β-D-Glucan Assay for the Diagnosis of Pneumocystis jirovecii Pneumonia: A Systematic Review and Meta-Analysis (CMI: Clinical Microbiology and Infection)
• Do patients with candidemia need an ophthalmologic examination? (OFID)
• Parasitic
• Progress Toward Global Dracunculiasis (Guinea Worm Disease) Eradication (CDC MMWR)
• The gut microbiota is essential for Trichinella spiralis—evoked suppression of colitis (PLoS Neglected Tropical Diseases)
• Symptomatic Entamoeba dispar Infections Among Men Who Have Sex With Men, New York City, 2018control (OFID)
• Angiostrongylus cantonensis Meningoencephalitis in Three Pediatric Patients in Florida, USA (Journal of the Pediatric Infectious Diseases Society)
• Miscellaneous 
• Snake phobia among the general population of Tamil Nadu, India(PLoS Neglected Tropical Diseases)
• Remote Practice of Infectious Diseases Through Telemedicine: Improving Access for Patients and Appeal for Physicians (OFID)
• Gauging Medical Students' Interests in Infectious Diseases (CID)
• Shaping the Future of Infectious Diseases: The Journey to Promote Value, Opportunity, and Positive Messaging (OFID)

Music is by Ronald Jenkees

Information on this podcast should not be considered as medical advice.