Jame and Callum are joined by Lee John and Ella for this episode around the arch-villain of atypical pneumonia and the bogeyman of every spa. Yes Legionella pneumophila (and friends) are addressed in depth whilst this podcast is aerosolised around the world.

Show notes for this episode here

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You'll be whooping with knowledge after listening to this one. Come hear all about Bordetella species. From pertussis to kennel cough you'll hear it all.

Show notes for this episode here

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It's the second Pharmacokinetics episode you never knew you wanted! Let’s talk about how antibiotics are distributed around the body once absorbed, using the examples of Amoxicillin and CallumShutUpicillin (listen to episode for clarification).

What exactly is the volume of distribution? Want a handy reference for the plasma protein binding of various antimicrobials? Then this is the episode for you! Check out our prep notes (including for this episode) here. 

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It's the Pharmacokinetics episode you never knew you wanted! Callum didn't know either, but never mind that let's talk about how antibiotics are absorbed, and how we can use that to improve our use of them in clinical practice.

Want ammunition for that oral switch? Got someone who's doubting oral antibiotics' effectiveness? Then this is the episode for you! Check out our prep notes (including for this episode) here. 

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In this final episode of the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the (mostly historical) pathogen Burkholderia mallei, causative agent of Glanders. 

We did it. We got to the end. 

Nonfermentors... Nobbled. 

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Post-publication, Callum and Jame give a little extra information on the SABATO trial in its final form compared to it's pre-publication state.

Final article here:
Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial, Kaasch, Achim J Valiente, Adoración et al. Lancet Infect Dis. 2024 Jan 17:S1473-3099(23)00756-9.
PMID: 38244557.
https://doi.org/10.1016/S1473-3099(23)00756-9

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JOURNAL CLUB, YO, IT’S A SABATO!!!

Join Jame and Callum as we travel back in time to when we recorded this deep dive into the SABATO trial pre-print, now peer-reviewed and published in the Lancet ID!

In the next episode we'll give a little update as to how the final article differs from the preprint (not much).

We also talked about in our FIS Highlights Episode 3.

We loved this trial and we hope you’ll all give it a read, it’s well worth it!

Article here:
Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial, Kaasch, Achim J Valiente, Adoración et al. Lancet Infect Dis. 2024 Jan 17:S1473-3099(23)00756-9.
PMID: 38244557.
https://doi.org/10.1016/S1473-3099(23)00756-9

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In this penultimate episode in the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the regionally important neglected tropical disease Melioidosis, caused by Burkholderia pseudomallei.

This episode was based disproportionately on the following article, and we extend our thanks to the authors for thoughfully publishing it so close to us wanting to do a podcast episode on Melioid!

Meumann, E.M., Limmathurotsakul, D., Dunachie, S.J. et al. Burkholderia pseudomallei and melioidosis. Nat Rev Microbiol (2023).

https://www.melioidosis.info/

Link to prep notes here.

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In this Episode, Callum reflect on his recent runaway success passing the FRCPath Part 2, passes on some tips and tricks for the exam, and then we talk about what 3 antibiotics we would take with us to a Desert Island (that has all pathogens and environments where you would find said pathogens, so not just a desert apparently).

'Prepping to Pass' episodes mentioned: 40, 42, 43 & 50.

The Table and Links mentioned in this episode can be found here: https://idiots.notion.site/70-Reflections-on-Part-2-2023-a193fd830c9b4d6c9381107471fcdbca

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How do you think about antibiotics?

This Christmas we give the best gift of all: no puns in an episode.
Join Jame and Callum as they talk about a method for thinking about and explaining antibiotics.

Here are the show notes for this episode: https://idiots.notion.site/69-Choosing-an-antimicrobial-4e7446a91ff6413aa14924a2ba905ffa 

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Did you think the  evidence base for Stenotrophomonas was bad? Well allow  us to introduce you to Burkholderia cepacia complex!

BCC is pretty niche but a key pathogen in people living with cystic fibrosis. We talk through the (very) limited treatment options and evidence base for this difficult bug.

Prep notes for this episode here: https://idiots.notion.site/68-Burkholderia-cepacia-complex-7bba8a7c74df490cb2e91d087a3cdb2a

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Callum and Jame wrap up their thoughts on the recent FIS conference. 

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The Spring Meeting of the British Infection Assocation is a must for UK infection trainees; In this week's episode Callum summarises for Jame (who was there, but didn't take any notes) the main learning points from the meeting.

Show notes for this episode here

BIA membership is FREE to UK infection trainees, reasonably priced for everyone else, and paid memberships come with online access to the Journal of Infection! Sign up today at https://www.britishinfection.org/join. 

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Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html

Mentioned in episode:
ESCMID brain abscess guidelines: https://www.sciencedirect.com/science/article/pii/S1198743X23003993#
ORAL study protocol: https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-021-05783-8

ACBLM/ALM: https://www.acb.org.uk/

Pathology networks: https://www.england.nhs.uk/pathology-networks/

UCLH/HTD: https://www.uclh.nhs.uk/our-services/find-service/tropical-and-infectious-diseases
uclh.parasitologyspr@nhs.net

Review article on anti-fungal resistance and global health: https://www.nature.com/articles/s41579-022-00720-1

NITCAR website: https://nitcollaborative.org.uk/wp/

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Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html

Mentioned in episode:

UCHL HLH protocol and referral details: https://www.uclh.nhs.uk/our-services/find-service/medical-specialties-1/hlh-service
SNAP trial: https://www.snaptrial.com.au/
SNAP trial email: snap-trial@unimelb.edu.au
SABATO (pre-print) https://www.medrxiv.org/content/10.1101/2023.07.03.23291932v1

RESISTANCE/The Mould that Changed the World: https://www.mouldthatchangedtheworld.com/

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In this episode Jame and Callum are joined by Louis, host of the let's talk micro podcast.

Listen in for a discussion on what a Biomedical Scientist is and how to become one. We explore the key details that clinicians need to add to their specimen request details; and ponder how laboratory managers can make this easier for clinicians.


How to request a test:
https://global.oup.com/academic/product/how-to-request-a-test-a-clinicians-guide-to-the-interpretation-and-evaluation-of-medical-tests-9780192866615?cc=gb&lang=en&

Let's talk micro podcast:
https://rss.com/podcasts/letstalkmicro/ 

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Ready for some startling Steno statistics? In this big 1-parter, Callum & Jame go through Stenotrophomonas maltophilia, from start to finish. 

Unlike Pseudomonas & Acinetobacter, Steno is much less commonly seen outside of ITU & the immunocompromised; but when it shows up you have to know what you’re doing. Luckily for you, there’s basically only 2 treatments! (In Europe: you’ll see what I mean).

2 crap puns in this one, so… get ready for that. 

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In Part 2 of our episodes on Acinetobacter we talk abouit resistance, and then do a deep dive into the evidence base for the management of CRAB: Carbapenem-Resistant Acinetobacter Baumanii-calcoaceticus complex.

Do have a look at the prep notes for this episode if you want more information on Acinetobacter.

Links to podcasts mentioned in this episode

ID:IOTS Episode 41: Bugs Without Borders

Febrile episodes 76 & 77: Piece de (Gram-negative) Resistance
Episode 76
Episode 77

For links to the papers we used, see the prep notes! 

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In this episode, Callum and Jame go over the second big family of nonfermentors, Acinetobacter. In part 1 we talk about the organisms themselves, risk factors, clinical syndromes and diagnostics before talking a little about treatment. 

In Part 2 (released next week) we’ll talk about Carbapenem-Resistant Acinetobacter Baumanii-calcoaceticus (CRAB), and resistance mechanisms in general. 

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In part 2, we discuss the limited treatment options for pseudomonas infection, some wildcard options and the resistance mechanisms that make Pseudomonas such a tricky bugger to treat! 

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It was a long time coming, but it’s here. Jame and Callum set off on our mini-series, Nobbling the Nonfermentors, starting with an introduction to glucose-nonfermenting organisms before moving on to the biggie: Pseudomonas aeruginosa! 

Part 2 next week covers treatment of Pseudomonas, including a deep dive into Pseudomonas resistance mechanisms. Stay tuned!

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Jame and Callum were delighted to be invited as guests to the podcast Microbe Mail by host Vindana (Vin) Chibabhai. Check out the Microbe Mail podcast:
https://microbemail.captivate.fm/  @microbemail

We discuss how bactericidal and bacteriostatic are defined, what the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) are and why this isn't as simple as it first seems. We then discuss specific clinical situations and where bactercidal vs static have been compared.

Links/papers mentioned in this episode:

The basics of beta lactamases

Wald-Dickler N, Holtom P, Spellberg B. Busting the Myth of ‘Static vs Cidal’: A Systemic Literature Review. Clin Infect Dis. 2018 17;66(9):1470–4.

Use of bacteriostatic agents in Neutropenic fever:

The RCT referred to in the abstract is here:
Jaksic B, Martinelli G, Oteyza JP, Hartman CS, Leonard LB, Tack KJ. Efficacy and Safety of Linezolid Compared with Vancomycin in a Randomized, Double-Blind Study of Febrile Neutropenic Patients with Cancer. Clinical Infectious Diseases. 2006 Mar 1;42(5):597–607

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Jame and Callum are together in person to talk about the importance of keeping your house in order. Being an infection specialist does not automatically make you an antimicrobial steward. We reflect on some challenges to being an antimicrobial steward  when practising infection medicine

The choosing wisely campaign mentioned by Jame:
https://www.choosingwisely.org/

A course on Antimicrobial Stewardship which is a good starting point:
https://www.futurelearn.com/courses/antimicrobial-stewardship

The IDSA guidance on AmpC production risk organisms mentioned by Jame:
https://www.idsociety.org/practice-guideline/amr-guidance/#AmpC%CE%B2-Lactamase-ProducingEnterobacterales

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Jame was there but Callum wasn't! The British Society for Antimicrobial Chemotherapy have several conferences throughout the year, including a Spring meeting with their AGM. But what topics were discussed, I hear you wonder? WELL WONDER NO MORE: Jame'll take you through it!

Notes for this episode here

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We were delighted to be joined by Dr Anastasia "Tash" Theodosiou to talk about breastfeeding, antibiotics and the risks of antibiotic harm to mum and baby. Tash is an infectious diseases/medical microbiology trainee, host of the HelloMicro blog and has volunteered as a Breastfeeding Peer Supporter.

*Note the NICE guidelines have been updated and do not recommend trimethoprim in any stage of pregnancy

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2 years. It’s been a hell of a ride. Here’s to 2 more. 

Links from this episode: 

KASIC 1-page evidence-summary on aminopenicillins for resistant enterococcal UTIs:  https://bit.ly/44CtNnq

AUDIENCE SURVEY!!! 

Please do fill this out, it would mean a lot to us: https://forms.gle/aCq2djmfKPjA6tkMA. 

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This is the urine antibiotic drug penetrance you never knew you wanted. Jame might be prouder of this than his own children. Callum, as you will be able to tell, remains indifferent*.

Figure out which antibiotics you can trust, and which you can't. Use the table in the prep notes and links to win arguments, justify treating 'resistant' organisms in the urine, BREAK HEARTS - you name it!

Enjoy! 

Prep notes for this episode: https://idiots.notion.site/UTI-Drug-Choice-5deb611895254444a040bf78d2003cdb

*To the episode, he thinks Jame's children are delightful. 

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Catheter-associated UTI: Callum’s nemesis. His white whale. His Sauron. His favourite rant. 

Want to know how favourite? Listen on!

Show notes for this episode here

Useful links (see show notes for more)
RICAT study
Chlorhexidine meatal cleaning

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Loyal Listeners! Free yourselves from this outdated language! Emancipate your hospitals from 'Escalation antibiotics'!

In today's episode, Callum and Jame rant for 35 minutes about how we talk about changing therapy, and how talk of escalating antibiotics leads to desire for 'big gun' antibiotics.

Apologies for Callum's audio quality on this episode. We'd apologise for Callum in general, but you chose to listen, really you've only yourself to blame.

Links:
Tunnocks Tea Cakes
Ledaig whisky
ID:IOTS guide to Aminoglycosides

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The title says it all. We're going back to the lab for this discussion. Join Jame and Callum as they have an in depth discussion about the nature of urine culture.

Prep notes for this episode available here. 

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Ever wondered what a clinical scientist is or how to become one? Are you a clinical scientist and looking to sit the FRCPath exams? Join Jame and Callum as they talk to Phillipa Burns and Vicki Fleming about their experiences in preparing for their FRCPath exams in microbiology.

Here are some of the resources mentioned during this episode:
Colour atlas of bacteriology
UK Reference laboratory manuals
Tropical Medicine Notebook
Bailey & Scott's Diagnostic Microbiology, 15th Edition

 Review agars from the manufacturer:
EO labs
Oxoid

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Welcome to the party pal! The penicillin allergy assessment and delabelling party, that is. Callum takes Jame through the latest evidence base in antibiotic allergy in general, and beta lactam allergy assessment and management in particular. 

Links: 
PENFAST Score paper: 
Trubiano JA et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. doi: 10.1001/jamainternmed.2020.0403.

Sulfonamide allergy paper here (couldn't find anything published more recently): 
Urbancic KF et al. Taking the challenge: A protocolized approach to optimize Pneumocystis pneumonia prophylaxis in renal transplant recipients. doi:10.1111/ajt.14498

Dutch beta lactam allergy guidelines: 
https://swab.nl/en/exec/file/download/192

And finally...
Norvell MR et al. Cefazolin vs. second-line antibiotics for surgical site infection prevention after total joint arthroplasty among patients with a beta-lactam allergy. https://doi.org/10.1093/ofid/ofad224

Yippee Ki-Yay, my delabellers, we'll see you in a fortnight. 

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Join Callum with guests Morgan Evans, Olivia Hawkes and Katy Hill for the final(?) part of the ECCMID 2023 highlights

ECCMID sessions discussed:
- Antimicrobial stewardship poster session
- Ethical dilemmas with antimicrobial therapy
- The value of diagnostic information for antimicrobial stewardship
- Tick borne diseases and prevention


Music: https://pixabay.com/music/acoustic-group-outrigger-144123/ 

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Join Callum with guests Andrew Seaton, Marianna Avellar, Hannah Pymont, Eva Garmendia, Sanjay Patel and Dave Hettle live from ECCMID 2023.

ECCMID sessions discussed:
- Fairytales or reality, checking some eminence paradigms for treatment of severe infections
- Neglected tropical skin diseases
- Non-canonical approaches to treatment of infections
- Paediatric interactive cases: dilemmas for the microbiologist and infection specialist
- Clinical grand round

For the AMR studio podcast: https://www.uac.uu.se/the-amr-studio/ 

BSAC paediatric pathways: https://bsac.org.uk/paediatricpathways/

Music: https://pixabay.com/music/acoustic-group-outrigger-144123/

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In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, finishes educating Callum and Jame (mostly Callum) on the concept of Microbiotoxicity!

This episode is part 2 of 2. Here we discuss: 

- What is microbiotoxicity?
- Risk factors for microbiotoxicity
- Which antibiotics are associated with microbiotoxicity?
- Mitigating microbiotoxicity

https://www.researchgate.net/profile/Anastasia-Theodosiou

https://x.com/doctoranastasia

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Join Callum with Guests Robert Ball, Kelly Bicknell & Rob Read live from ECCMID 2023. 

ECCMID sessions discussed:

• Antibiotic stewardship for urinary tract infections: challenges and opportunities
• Viral Infection in immunosuppressed patients: what is new?
• Responsible publishing in CM/ID
• Secondary haemophagocytic lymphohistiocytosis and infectious diseases

Review article on HLH:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094004/

Music:
https://pixabay.com/music/acoustic-group-outrigger-144123/

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Callum is reunited with Jame following their separation at ECCMID 2023. Callum shares some highlights including Archaea and their role in human health, Digitalisation within the microbiology lab and the ESCMID/IDSA interview

Links to publications on Archaea:
https://www.moissleichingerlab.com/projects/
https://twitter.com/chmoei?lang=en

Digitalisation and machine learning in microbiology presentation link: https://appliedmicrobiologyresearch.net/en/blog/keynote-by
https://twitter.com/AppliedMicrobi2?s=20

Carlos del Rio, president of the IDSA
https://twitter.com/CarlosdelRio7?s=20

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Jame rides solo today, going over the beta-lactamase inhibitors, old and new, how to think about them and when to use them in anger. 

New Show notes format! Available at https://idiots.notion.site/Beta-Lactamase-Inhibitors-f9999b6a4867470996a31c53e661b5ac

NB: For now all old show notes are available in the usual Onedrive folder. 

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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Jame and Callum are joined by the one and only Sara Dong of Febrile fame to look at the American Board of Internal Medicine's Infectious Disease Certification Exam. 

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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Jame and Callum are joined by semi-recent FRCPath Microbiology part 1 exam passers Callum and Jame to discuss how best to prepare for this exam. This exam is sat by all infection trainees in the UK, as well as other health care professionals working in infection such as clinical scientists. 

Full revision resources notes available in the linked OneDrive folder below (if you can't access it let us know). 

Let us know once you pass! (Disclaimer: previous sentence for engagement purposes only, please do not let us know once you pass). 

Support the show

Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod

Jame and Callum are joined by Vin from Microbe Mail to discuss the management of Difficult to Treat Resistance (DTR) Gram negative infections in South Africa.

If you haven't already check out Microbe mail for a high quality infection podcast linking the lab and clinical management.... wait that sounds familiar!

Vin is a associate Professor in Clinical Microbiology at the University of the Witwatersrand, Johannesburg, South Africa and a practising clinical microbiologist with the National Health Laboratory Service. She is passionate about microbes (of course), antimicrobial resistance, antimicrobial stewardship, diagnostics, healthcare associated infections, fungal infections, One Health...let's just say it's a very long list!

References:

• Metallo-β-lactamase resistance in Enterobacteriaceae is an artefact of currently utilized antimicrobial susceptibility testing methods 
• Best practices: Appropriate use of the new β-lactam/β-lactamase inhibitor combinations, ceftazidime-avibactam and ceftolozane-tazobactam in South Africa
• Colistin Monotherapy versus Colistin plus Meropenem Combination Therapy for the Treatment of Multidrug-Resistant Acinetobacter baumannii Infection: A Meta-Analysis

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app!

Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod

Jame and Callum are joined by recent FRCPath Microbiology part 2 exam passers Olly and Rob to discuss how best to prepare for the exam. This is the final exam required to qualify as a medical/clinical microbiologist in the UK. 

Full revision resources notes available in the linked OneDrive folder below (if you can't access it let us know!). Let us know once you pass!

Support the show

Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod

It's time for journal club! Jame and Callum discuss community acquired pneumonia treatment and a paper from 2021 which examines shorter duration therapy for patients responding to therapy.

Paper discussed:
Dinh, Aurélien et al. “Discontinuing β-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo-controlled, non-inferiority trial.”
Lancet 2021;397: 1195-1203.
doi:10.1016/S0140-6736(21)00313-5

Shorter is Better site:
https://www.bradspellberg.com/shorter-is-better

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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In this episode as requested on twitter (sort of),  Callum & Jame compare and contrast Gram positive & negative bacteraemia. Happy new year!

Please also see our older episode on bloodstream infection: www.buzzsprout.com/1782416/9162105-5-back-to-bacteraemia

SABATO trial details here: https://twitter.com/sebpoule/status/1518496524552056833?s=46&t=Dre0YLRm_gwnKQ8OakDarw

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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This Christmas, Jame shares a tale of woe: the rise and fall of Plazomicin, a hapless victim of antibiotic market forces. The conversation then proceeds/degenerates into a discussion of the economics of Antimicrobials in general, with a focus on the ‘Netflix’ model being piloted in the UK.  

WE’LL BE BACK NEXT YEAR SEE YOU THEN

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, returns to talk about her favourite subject! 

This episode is part 1 of 2. Here we discuss: 
- What is the microbiome
- Viewing the microbiome as an organ system
- The microbiome's association with disease
- How we study the microbiome

Stay tuned for part 2 (in 1-2 weeks depending on editing), when we talk about the effect of medicine on the microbiome, microbiotoxicity, and what you can do to keep your patients' microbiomes in tip top shape! 

https://www.researchgate.net/profile/Anastasia-Theodosiou

https://x.com/doctoranastasia

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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Join Jame and Callum as they take a deep dive into urinalysis, a commonly (mis)used test for UTI (and other conditions). This test put you into murky waters when used clinically and we hope to give some information to avoid being a pisse prophet.

Some sources referred to in this episode:
NICE Clinical knowledge summary
SMI 41: Investigation of urine

Summary article of PPV and NPV for urinalysis:
- Diagnosis and treatment of urinary tract infections across age groups, AJOG, 2018

Performance of LE and Nitrite at differing levels of bacteruria:
-  Evaluation of Leukocyte Esterase and Nitrite urine dipstick, J Clin microbiol, 1999

Review of urinalysis diagnostic utility by presenting symptoms:
- Does this woman have an acute uncomplicated urinary tract infection? JAMA 2002

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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Callum and Jame discuss the HACEK organisms (apart from Haemophilus which we discussed in episode 32). 

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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An atypical episode about pneumonia. Callum and Jame discuss their pet peeves. 

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Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

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Feel like giving back? Donations of caffeine gratefully received!
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Callum and Jame talk about everyone's favourite antibiotic class that covers Staph, Pseudomonas and Gram negatives, is predominantly renally excreted and isn't a quinolone, the aminoglycosides. We go over classification, mechanism of action, spectrum, resistance mechanisms, PK/PD, penetrance to various tissues, toxicity, and dosing. 

This is a companion piece to our star appearance on Febrile in August: https://player.captivate.fm/episode/0777091c-0991-42d4-89a9-4032d77b4fa5

Support the show

Questions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.social

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app!

Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod