Howard Forman and Harlan Krumholz, two Yale physician-professors, discuss the latest news and ideas in healthcare and seek out the truth amid the noise. Produced with the Yale School of Management and the Yale School of Public Health. New episodes are available every Thursday.
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Howie and Harlan are joined by Vanessa Cooper, a Yale School of Medicine neurologist, to discuss the causes of migraines and promising new treatments for the disorder. Harlan discusses his approach as a journal editor to the use of AI in academic writing; Howie reports on the premium tax credits for insurance purchased through Affordable Care Act exchanges that are at stake in the government shutdown.
Howie and Harlan are joined by Kate Heilpern, president of Yale New Haven Hospital, to discuss the innovation and adaption needed to lead NewYork-Presbyterian Hospital through the worst of the COVID-19 pandemic, and how Yale New Haven Health structures itself to provide quality care across five hospitals. Harlan reflects on the many biotech startups emerging from Yale; Howie responds to the Trump administration's assertion of a link between acetaminophen and autism.
Howie and Harlan are joined by Yale School of Medicine geriatrician Barry Wu, who provides a framework for family caregivers and physicians to understand the needs of older adults. Harlan reports on Congress's shifting approach to funding research; Howie reflects on a survey showing that many college students believe that violence is an acceptable way to protest a campus speaker.
Howie and Harlan are joined by physician, scientist, and author Eric Topol to discuss his new book, Super Agers: An Evidence-Based Approach to Longevity; the potential of individualized polygenic risk scores; and the dangers of the protein craze.
Howie and Harlan discuss Dr. Vinay Prasad’s departure from the FDA after a backlash against his decisions on Sarepta’s Duchenne muscular dystrophy gene therapy. Also examined: AI in clinical settings, changes in NIH grantmaking, and the 60th anniversary of Medicare and Medicaid.
Katelyn Jetelina: A Visit from Your Local Epidemiologist
Épisode 184
jeudi 24 juillet 2025 • Durée 38:04
Howie and Harlan are joined by public health communicator Katelyn Jetelina for updates on COVID-19 and other issues, and to discuss how her emails to students and colleagues in the early days of the pandemic turned into a platform with global reach. Harlan looks at how AI is being used on both sides of the battle between providers and insurers over claims; Howie reports on a setback with a promising gene therapy for Duchenne muscular dystrophy.
Howie and Harlan are joined by Seth Berkowitz, an internist and health equity expert, who argues that we know how to keep people healthier but are lacking the political will and commitment to do so. Harlan reports on a rapidly growing AI platform for doctors; Howie explains why the budget bill could reduce access to medical school.
Howie and Harlan are joined by Azita Emami, dean of the Yale School of Nursing, to discuss the school’s approach to training nurses who can have a seat at the table of healthcare decision-making. Harlan reports on his new study showing the low levels of evidence required for medical devices in the FDA’s Breakthrough Devices Program; Howie provides some good news about infectious diseases including malaria and HIV.
Howie and Harlan discuss the alarming healthcare cuts proposed in the budget bill currently moving through Congress, recent breakthroughs in HIV prevention and diabetes treatment, and the stark contrast between scientific progress and the deep structural flaws in the U.S. healthcare system.
Stephen Waxman: Easing the Horrors of Chronic Pain
Épisode 180
jeudi 26 juin 2025 • Durée 36:34
Howie and Harlan are joined by Stephen Waxman, a leading neurology researcher, to discuss the promise of new methods developed by his lab to treat the ravages of pain. Harlan talks about the importance of ratings for Medicare Advantage plans; Howie assesses two sobering new reports on the solvency of Medicare.
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