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TitreDateDurée
Halle Tecco: Investing in Women’s Health21 Nov 202400:42:00
Rahul Rajkumar: Intensive Home-Based Care for High-Need Patients14 Nov 202400:39:09
Margaret McGovern: Building an Integrated Health System12 Sep 202400:34:23
Dr. Utibe Essien: Who Gets Access to Innovative Treatments?20 Oct 202200:37:44
Taking the Pulse13 Oct 202200:33:06
Dr. Ania Jastreboff: The Revolution in Obesity Medication06 Oct 202200:35:13
Ingrid Nembhard: Improving Healthcare Organizations to Improve Health29 Sep 202200:31:13

Harlan discusses the problem of “financial toxicity”—how medical bills can wreak havoc in vulnerable patients’ lives. Howie reflects on the protests in Iran and the precariousness of the freedoms we enjoy in the United States. And they are joined by Ingrid Nembhard of the University of Pennsylvania to discuss her work on the organizational factors that shape patient care.

Links:

Cancer.gov: Financial Toxicity

“They Were Entitled to Free Care. Hospitals Hounded Them to Pay.”

Harlan Krumholz: “Atherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United States”

Harlan Krumholz: “Out-of-Pocket Annual Health Expenditures and Financial Toxicity From Healthcare Costs in Patients With Heart Failure in the United States”

Ingrid Nembhard: “Responding to Covid-19: Lessons from Management Research”

Ingrid Nembhard: “COVID-19 Inspired Creativity In Health Care: Lessons For Management And Policy”

“Can the CDC Repair Its Reputation?”

Ingrid Nembhard: “A systematic review of research on empathy in health care”

Ingrid Nembhard: “Making it safe: the effects of leader inclusiveness and professional status on psychological safety and improvement efforts in health care teams”

Ingrid Nembhard: “Perceived Usefulness of Patient Narrative Feedback in Primary Care Settings”

“Why Iranian women are burning their hijabs after the death of Mahsa Amini”

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Jonathan Rothberg: The Scientist-Entrepreneur22 Sep 202200:30:53

Howie and Harlan react to President Joe Biden’s declaration that the pandemic is over. Then they’re joined by Jonathan Rothberg, a Yale-trained scientist who has created new methods for sequencing DNA and founded a series of successful biotech companies.

Disclosure: Harlan Krumholz is a consultant to Tesseract, a portfolio company of 4 Catalyzer, which was founded by Jonathan Rothberg.

Links:

“Biden: ‘The pandemic is over’”

Eric Topol: “To boost or not to boost

“An integrated semiconductor device enabling non-optical genome sequencing”

”Butterfly Network Distributes 500 Butterfly iQ+ Devices to Healthcare Workers in Kenya to Transform Maternal and Fetal Health”

”AI Estimation of Gestational Age from Blind Ultrasound Sweeps in Low-Resource Settings”

Butterfly Network

Protein Evolution

Hyperfine

”Uncovered Medical Bills after Sexual Assault”

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Dr. Jeremy Faust: Is COVID Over? It's Complicated.15 Sep 202200:36:56
Dr. Esther Choo: The View from the Emergency Department08 Sep 202200:33:55

Harlan outlines his new study tracking excess mortality over the course of the pandemic in the highly vaccinated state of Massachusetts; Howie discusses how the Inflation Reduction Act will tackle drug prices. They're joined by Dr. Esther Choo to talk about life as a doctor on social media and the crisis facing emergency departments.

Links:

Esther Choo: “Covid-19 is pushing doctors to the brink. Medicine needs to recognize they’re human and need help.”

“Uncoupling of all-cause excess mortality from COVID-19 cases in a highly vaccinated state”

“New York Governor Lifts Mask Mandate for NYC Subways”

White House Fact Sheet: The Inflation Reduction Act Supports Workers and Families

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Learn more about the MD-MBA program at Yale.

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Beating the Outbreaks04 Aug 202200:16:33

Monkeypox, polio, and COVID-19 have all received the World Health Organization’s rarely used global health emergency designation. Howie and Harlan offer a needed sense of proportion alongside health information, updates on research, and policy developments for the grim trio of diseases.

Dr. James Hamblin: Should You Stop Washing?28 Jul 202200:32:16

Howie and Harlan talk with Dr. James Hamblin, a journalist and a lecturer at the Yale School of Public Health. They discuss his approach to communicating about public health, his prescient February 2020 article on COVID-19, and why he’s quit taking showers.

Links:

James Hamblin: The Body

“You’re Likely to Get the Coronavirus”

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Teresa Chahine: The Social Entrepreneur’s Guide to Making Change21 Jul 202200:31:11

Howie and Harlan are joined by Teresa Chahine, the Sheila and Ron ’92 B.A. Marcelo Senior Lecturer in Social Entrepreneurship at Yale SOM. They discuss how social entrepreneurs use an interdisciplinary, iterative, community-centric approach to innovation to create self-sustaining solutions to problems in public health and other areas.

Links:

“Tirzepatide Once Weekly for the Treatment of Obesity”

Teresa Chahine: “Toward an Understanding of Public Health Entrepreneurship and Intrapreneurship”

Teresa Chahine: Social Entrepreneurship: Building Impact Step by Step, 2nd Edition (December 2022)

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Lee Schwamm: Smarter Healthcare Systems With AI25 Jul 202400:35:21
Jennifer Miller: Scoring the Ethics of Pharma Companies14 Jul 202200:35:20

Howie and Harlan discuss Harlan's large new study tracking the trajectory of patient safety in hospitals, and consider how individuals should respond to the latest COVID-19 variants. They're joined by Jennifer Miller, a Yale bioethicist and the director of the Good Pharma Scorecard, which evaluates the performance of pharmaceutical companies on measures like the transparency of clinical trials and the accessibility of medicines. 

Links:

“New Federal Study Evaluates the Safety of US Hospitals and the Answer Is…”

“Trends in Adverse Event Rates in Hospitalized Patients, 2010-2019”

Good Pharma Scorecard

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Rethinking Research07 Jul 202200:32:28
Dr. Rebekah Gee: Can We Bring Family Healthcare to the Home?30 Jun 202200:32:58

Harlan reviews the latest COVID-19 research, and Howie reflects on the vast ramifications of the Dobbs decision overturning Roe v. Wade. They’re joined by Dr. Rebekah Gee, an ob-gyn and the CEO of Nest Health, which aims to deliver care to vulnerable children and their parents at home. She also describes her experience as a pro-choice physician serving as secretary of the Louisiana Department of Health.

Links:

Rebekah Gee discusses letters from her late mother on This American Life. 

About Nest Health

“The War On Abortion Could Turn The US Into A Police State”

“The dynamics of SARS-CoV-2 infectivity with changes in aerosol microenvironment”

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Gregg Gonsalves: An Inspiring Nonlinear Path to Impact23 Jun 202200:31:10

Howie and Harlan are joined by Yale epidemiologist and MacArthur ‘genius’ Gregg Gonsalves to discuss his non-traditional route to improving responses to global public health challenges.

Links:

Eric Topol on COVID reinfections

Harlan’s Twitter thread on insurance debt

“Health Savings Accounts No Longer Promote Consumer Cost-Consciousness” Sherry Glied in Health Affairs

The Best Little Boy in the World

Learn more about the MBA for Executives program at the Yale School of Management.

Your Co-host’s Remarkable Career16 Jun 202200:29:02

Harlan interviews Howie about his life as a doctor and teacher, including how a radiologist without a PhD got to teach economics at Yale, why he engages in the daily battles that come with speaking out on Twitter, and the extraordinary return on investment from time spent mentoring young people.

Links:

Arnold Schwarzenegger on deaths attributable to pollution

“Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit”

“Climate Change, Fossil-Fuel Pollution, and Children’s Health“

Merriam-Webster on the origin of the word “doctor”

Learn more about the MBA for Executives program at the Yale School of Management.

 

Dr. Seth Trueger: When the Doctor Becomes a Patient09 Jun 202200:36:15

Howie and Harlan are joined by Dr. Seth Trueger of Northwestern University, who was diagnosed with a rare autoimmune disorder in 2020. They discuss his experience navigating the healthcare system as a patient and what he’s learned about the challenges facing people with complex medical issues.

Links:

2022 Medicare Trustees Report 

“A Cancer Trial’s Unexpected Result: Remission in Every Patient”

“PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer”

Seth Trueger: “The Best Bad News”

“Public Finance Balance of Smoking in the Czech Republic”

Learn more about the MBA for Executives program at the Yale School of Management

Thomas Balcezak: Can Hospitals Recover from COVID-19?02 Jun 202200:35:10

Harlan explains what the research says about the immunity acquired from a COVID-19 infection, and suggests a framework for thinking about exposure risk. Then Howie and Harlan are joined by Thomas Balcezak, chief clinical officer at the Yale New Haven Health System. They discuss the financial and human capital challenges faced by hospitals in the wake of the pandemic.

Links:

“Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2”

“Medical Education in the United States and Canada” (The Flexner Report)

About Yale New Haven Health

“Mass General Brigham says it will reduce spending by $70m annually”

“US Mass Shootings, 1982–2022: Data From Mother Jones’ Investigation”

Dr. Amy Justice: Unlocking the Insights in Healthcare Data26 May 202200:34:03
Jason Schwartz: Building a Better Vaccine Policy19 May 202200:34:23
Dr. Cecelia Calhoun: Taking on Systemic Inequities12 May 202200:35:26

Howie and Harlan are joined by Dr. Cecelia Calhoun ’21, a Yale sickle cell disease specialist and a recipient of Yale SOM's Pozen-Commonwealth Fund Fellowship in Health Equity Leadership. They discuss Calhoun's journey from growing up in Detroit to a clinical and research career focused on the health of the Black community.

Links

Pozen-Commonwealth Fund Fellowship in Health Equity Leadership

“Heartstopper is dazzlingly brilliant TV – I wish my lonely younger self could have seen it”

“The Secrets Ed Koch Carried”

Joshua Sharfstein: Policy and Health18 Jul 202400:38:50

Howie and Harlan are joined by Joshua Sharfstein, a longtime public health official in federal, state, and local government, to discuss the state of the opioid epidemic, lessons from the COVID-19 vaccine rollout, and our readiness for a bird flu outbreak. Harlan reports on the summer surge in COVID-19; Howie remembers his mentor Gail Wilensky, a health economist who directed Medicaid and Medicare programs and led many other organizations over a 50-year career. 

Links:

COVID-19 Update

CDC: COVID Data Tracker

CDC: COVID-19 Current Wastewater Viral Activity Levels Map

“What to Know About COVID FLiRT Variants”

Joshua Sharfstein

Joshua Sharfstein: The Public Health Crisis Survival Guide: Leadership and Management in Trying Times

Joshua Sharfstein: The Opioid Epidemic: What everyone needs to know

“How Can Over-the-Counter Naloxone Prevent Opioid Overdose Deaths?”

CDC: H5 Bird Flu: Current Situation
“Millions of US Children Experience Range of Long COVID Effects”

Joshua Sharfstein: “The Role for Policy in AI-Assisted Medical Diagnosis”
“External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients”

“Epic’s overhaul of a flawed algorithm shows why AI oversight is a life-or-death issue”

Podcast: “Baltimore cut infant mortality and helped moms thrive, too”

Remembering Gail Wilensky

“In Remembrance Of Gail Wilensky”

“Gail Wilensky, Former CMS Administrator, Dies at 81”

“In Memoriam: Gail Wilensky, Renowned Health Economist & NORC Trustee”
Gail Wilensky: “The Health Care Quality Improvement Initiative”


Learn more about the MBA for Executives program at Yale SOM.

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Dr. Gail D’Onofrio: Grappling with the Opioid Epidemic05 May 202200:36:56

Howie and Harlan are joined by Dr. Gail D’Onofrio, Yale's Albert E. Kent Professor of Emergency Medicine. They discuss the medications available for opioid addiction and the policy changes needed to allow those treatments to save more lives. 

Links

“Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults”

“Medication for Opioid Use Disorder After Nonfatal Opioid Overdose and Association With Mortality: A Cohort Study”

Melinda Irwin: Can Nutrition and Exercise Improve Cancer Outcomes?28 Apr 202200:33:23
Sherry Glied: Getting Ready for the Next Pandemic21 Apr 202200:28:33

To do better in the next pandemic, Sherry Glied, dean of New York University’s Robert F. Wagner Graduate School of Public Service, argues we must ensure that policymakers get answers to their most pressing questions. She joins Howie and Harlan in a conversation about incentivizing relevant research and systematically synthesizing data into actionable information.

Lauren Taylor: Ethics and Public Health14 Apr 202200:34:34

Howie and Harlan talk with NYU’s Lauren Taylor about the “dirty hands problem” and other ethical dilemmas inherent in efforts to improve health.

Zeke Emanuel's Provocative Advice on Making Healthcare Better07 Apr 202200:40:17

Howie and Harlan are joined by Dr. Ezekiel Emanuel, a leading expert on health policy and medical ethics, for a conversation about how to bring greater efficiency and agility to the generation of healthcare knowledge.

Dr. Daniel Stein: What the Data Says about Your Doctor31 Mar 202200:32:46

Howie and Harlan discuss a new study showing that moderate drinking doesn’t have health benefits after all. Then they’re joined by Dr. Daniel Stein, CEO of Embold Health, which uses clinical data to identify the best-performing doctors and give feedback to those whose treatment isn’t based on the latest evidence. 

Edward Kaplan: What Does Wastewater Reveal about COVID-19?24 Mar 202200:35:24

Howie and Harlan are joined by Yale operations expert Edward Kaplan, who uses mathematical models to understand a variety of processes. They discuss Kaplan’s ongoing research tracking COVID-19 infections through sewage, which bypasses the biases inherent in data from testing and even hospitalization.

Dr. Lakshmanan Krishnamurti: Hope for Sickle Cell Patients17 Mar 202200:35:27

Howie and Harlan are joined by Dr. Lakshmanan Krishnamurti, chief of pediatric hematology and oncology at the Yale School of Medicine and an expert on sickle cell disease. They discuss promising new treatments that can effectively cure the painful disease for some patients. 

Dr. Kristin Mattocks: Advancing the Health of Women Veterans10 Mar 202200:35:17

Howie and Harlan are joined by Dr. Kristin Mattocks, a researcher at the University of Massachusetts and the Department of Veteran's Affairs. They discuss her research on the complexities of healthcare for the growing number of women veterans. 

Dr. Mandy Cohen: Delivering Health, Not Just Healthcare03 Mar 202200:34:53

Howie and Harlan talk with Dr. Mandy Cohen, former secretary of the North Carolina Department of Health and Human Services and the CEO of Aledade Care Solutions. They discuss how to create the incentives and infrastructure needed for better outcomes for all patients.

 

Kate Goodrich: A Better Model for Care11 Jul 202400:39:15
Dr. Ijeoma Opara: Partnering with a Community24 Feb 202200:37:19

Howie and Harlan talk with Dr. Ijeoma Opara of the Yale School of Public Health about the impact of persistent violence on mental health among urban youth and the power of community-based participatory research. 

Dr. Saad Omer: Lessons Learned about Vaccine Hesitancy17 Feb 202200:33:01

Howie and Harlan are joined by Dr. Saad Omer, director of the Yale Institute for Global Health. They discuss mistakes made in the rollout of COVID-19 vaccines and how to avoid a crisis in childhood immunizations. 

Dr. Emily Wang: Mass Incarceration and Health10 Feb 202200:33:12

Howie and Harlan are joined by Dr. Emily Wang, director of Yale's SEICHE Center for Health and Justice, to discuss the health effects of mass incarceration on the imprisoned and their families and communities.

Dr. Akiko Iwasaki: Is Long COVID One Disease or Many?03 Feb 202200:33:42

Howie and Harlan talk with Dr. Akiko Iwasaki about her research trying to understand the cause or causes of long COVID, which has over 200 reported symptoms.

Dr. Randi Epstein: Medical Storytelling27 Jan 202200:31:50

Howie and Harlan discuss two recent studies (one of them co-authored by Harlan) illustrating the health impacts of racism. Then they're joined by Randi Epstein, a physician and journalist whose most recent book is Aroused: The History of Hormones and How They Control Just About Everything.

Nathan Grubaugh: Genomic Surveillance20 Jan 202200:31:55

Howie and Harlan are joined by Yale epidemiologist Nathan Grubaugh. They discuss the utility of rapid antigen tests and Grubaugh's work tracking the evolution of COVID-19 variants.

From COVID or with COVID?13 Jan 202200:29:02

Howie and Harlan talk about the patients who test positive for COVID-19 after being admitted to the hospital for something else, and other health issues in the news, including the explosion in healthcare spending last year, a controversial Alzheimer’s drug, and the consequences of underinsurance in the United States.

Anne Wyllie: The Latest on Omicron06 Jan 202200:31:57

Howie and Harlan discuss the state of the omicron surge and what we know and don’t know about the variant. Then they’re joined by Yale scientist Anne Wyllie, whose new research casts doubt on the ability of rapid antigen tests to detect asymptomatic omicron infections.

Dr. Albert Ko: A Wider View of COVID-1923 Dec 202100:36:45

Howie and Harlan are joined by Dr. Albert Ko, a Yale epidemiologist who has advised Connecticut governor Ned Lamont. They discuss the state of the pandemic, rebuilding global public health infrastructure, and what omicron tells us about future variants.

Fiona Scott Morton: Taming Healthcare Costs16 Dec 202100:30:31

Howie and Harlan are joined by Yale economist Fiona Scott Morton, an expert on competition in healthcare and other industries. They discuss the forces driving up healthcare costs in the U.S. and the steps that Scott Morton and her colleagues have proposed to bring them under control.

Timothy Westmoreland: Healthcare at the Supreme Court03 Jul 202400:40:53

Howie and Harlan are joined by Timothy Westmoreland to discuss his long career in health policy and law, and the far-reaching consequences of the Supreme Court decision overturning Chevron deference. Harlan looks at President Joe Biden's debate struggles; Howie reports on the many healthcare-related Supreme Court decisions. 

Links:

The Presidential Debate

Harlan Krumholz: “Did Cold Medications Affect Biden's Debate Performance?”

CNN Presidential Debate: President Joe Biden and former President Donald Trump

Press Briefing by Press Secretary Karine Jean-Pierre, July 2, 2024

“Biden's Evolving Reasons for His Bad Debate: A Cold, Too Much Prep, Not Feeling Great and Jet Lag”

Timothy Westmoreland

Timothy Westmoreland: “Henry Waxman, the Unsung Hero in the Fight Against AIDS”

“LGBTQ History Month: The early days of America's AIDS crisis”

Cornell Law School Legal Information Institute: Chevron deference

Ballotpedia: Skidmore deference

“How the Chevron case has roiled U.S. healthcare agencies” 

SCOTUSblog: Corner Post, Inc. v. Board of Governors of the Federal Reserve System

“Supreme Court appears likely to allow abortion drug to remain available”

The Supreme Court

“Implications for Public Health Regulation if Chevron Deference Is Overturned”

Supreme Court opinion: Murthy, Surgeon General, et al. v. Missouri et al

SCOTUSblog: Food and Drug Administration v. Alliance for Hippocratic Medicine

Cornell Law School Legal Information Institute: Moyle v. United States

Supreme Court of the United States

Health & Veritas Ep. 77: Megan Ranney: What’s Next for Public Health?


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Liza Fisher: Long COVID09 Dec 202100:32:08

Howie and Harlan are joined by Liza Fisher to talk about her experience navigating the medical system and advocating for patients while enduring 18 months of debilitating COVID symptoms. Fisher is a participant and co-author (with Harlan) for a new study examining internal tremors and vibrations among long COVID patients. 

Dr. Joseph Ross: Omicron; The Drug Approval Process30 Nov 202100:33:57

Howie and Harlan discuss what we know and don’t know about the newly identified omicron variant. Then they’re joined by Dr. Joseph Ross to discuss the strengths and weaknesses of the FDA’s process for approving new drugs.

Dr. Rohan Khera: AI, Machine Learning, and Medicine24 Nov 202100:32:53

Howie and Harlan talk with Dr. Rohan Khera, a Yale cardiologist whose research interests include the use of advanced data science tools to improve diagnosis and treatment. They discuss how artificial intelligence and machine learning can supplement human expertise in summarizing current literature, interpreting electrocardiograms, and other areas.

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