Explorez tous les épisodes du podcast Global Health Conversations
| Titre | Date | Durée | |
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| #25: Shaping Public Health & Epidemiology: The Story of John Snow and the Broad Street Pump | 27 Oct 2024 | 00:14:42 | |
A Storytime: | |||
| #24: What is the Pandemic Accord, really? | 29 Sep 2024 | 00:27:42 | |
A walkthrough. The Pandemic Accord is a proposed global agreement aimed at strengthening pandemic prevention, preparedness, and response. Emerging in the aftermath of COVID-19, the accord aims to address gaps in international coordination, surveillance, and equitable access to medical countermeasures, globally.
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| PROMO: Dental Dialogue: Prioritising Oral Health in Public Health - Available 31 March 2024 | 17 Mar 2024 | 00:02:51 | |
In this episode we discussed oral health as a public health issue. Discussing system challenges, incentivisation and disincentivasation, dental caries as the most common infectious disease, bacteria and the use of antibiotics. | |||
| #16: Tackling Cervical Cancer: Health Equity in Focus (International Women's Day Special) | 17 Mar 2024 | 00:21:55 | |
In this episode, in recognition of International Women's Day, we talk about cervical cancer and discuss its significance as a symbol of global health disparities and gender inequality. Cervical cancer incidence is exacerbated by socio-economic factors and disproportionately affects women in poverty. We discuss the importance of HPV vaccination, regular screening, and innovative prevention strategies like diagnostic tools to enable self-sampling. And the incredible toll of the devastating disease. 2. HPV self-sampling for cervical cancer screening: a systematic review of values and preferences: https://pubmed.ncbi.nlm.nih.gov/34011537/ 4. Podcast Episode: The Role of Storytelling in Women's Health | |||
| #15: Why do Americans Pay (so much) More for Healthcare? | 04 Feb 2024 | 00:34:03 | |
Check out the newsletter
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| #14: What does Sustainability look like in the Pharmaceutical Industry? (ft. Elisabetta Marani) | 26 Nov 2023 | 00:45:06 | |
This is the official last episode of Season 1! The Global Health Conversations Newsletter continues throughout the holidays until we're back after the Christmas holidays. Click here to Sign up to the free Global Health Conversations fortnightly newsletter. It is packed with the latest news in global health with themes each fortnight. You will also be notified when the next exciting interview is up! | |||
| #13: Non Disease Related Causes of Death: Gender-Based-Violence, a public health issue | 12 Nov 2023 | 00:46:44 | |
*****If you or a friend or loved one has been affected by the issues raised in this episode, I strongly encourage you to 1. Click here to find a domestic violence hotline or helpline near you in your country please speak to someone who will understand your situation and help. 2. Delete your search history and stay safe. ***** | |||
| #12: Global Health Quiz & Introduction to Global Health Fundamentals | 15 Oct 2023 | 00:59:59 | |
(Note: I was unfortunately unable to add the supplementary slides to the show notes. However, the image described in question 8 is in this week's Newsletter. Thanks for understanding and I hope you enjoyed the episode! If so, it really helps me if you leave me a kind, cheeky little five star rating ;) Thank you, Friend, for being part of the Conversation.) 1. What percentage of the world lives in extreme poverty today? _______ _______
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| #11: Universal Health Coverage: Health Systems Strengthening, Tech Transfer & Local Manufacturing of Vaccines & Biologics (Part 2) | 01 Oct 2023 | 00:34:42 | |
Timestamps:
1. Health Service Delivery 2. Health Workforce Development - health workforce has been a cornerstone of discussions 3. Health Infrastructure and Equipment: 4. Health Information Systems: 5. Health Financing:
6. Governance and Leadership:
7. Community Engagement and Empowerment:
8. Collaboration across sectors:
9. Research and Innovation:
10. Emergency Preparedness and Response:
11. Equity and Inclusivity:
12. Monitoring and Evaluation:
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| #10: The Role of Storytelling in Women’s Health (ft. Loredana Marta) | 17 Sep 2023 | 00:42:39 | |
We discussed the role and impact of storytelling on women’s health and explored inequities that exist in this area. We also discussed health tech and the many persisting shortcomings that impact women’s health, treatment and lives. Loredana Marta pens a newsletter under the name Vulvarina about how sexism interferes with our lives in unseen ways, in areas ranging from medical care, to industrial design and social dynamics. Her storytelling is stats- and fact-based, letting her legal background shine through, jazzed up with approachable anecdotes of mundane London life. She spent the last two years in the startup scene, where along with her two cofounders, she built OPEN social, bringing genuine conversations back to social media by matching people based on their moods. Writer and tech gal/lady (?) is currently exploring female health and digitalisation, as well as a gender and ethnicity personalised approach to medical research and care. If you're not yet subscribed to the Global Health Conversations fortnightly newsletter, click here to check it out | |||
| #9: How Medical Countermeasures are vital to Pandemic Preparedness within the context of Disease X | 03 Sep 2023 | 00:22:57 | |
Sign up to the Fortnightly Newsletter here In today’s episode our Conversation was centered around the role of Medical countermeasures (MCMs) in pandemic preparedness and we also touched on the concept of Disease X. Medical countermeasures refer to the measures and products aimed at addressing the medical needs arising from infectious disease outbreaks. The COVID-19 pandemic underscored deficiencies and requirements in ensuring a swift, efficient, and equitable response to global infectious disease outbreaks. One significant concern lies in the institutional capacity required to advance research and development and introduce novel medical countermeasures (MCMs) for pandemics or diseases with pandemic potential to the market. An all-encompassing perspective that guarantees equitable and sustainable access to MCMs involves expeditious progress throughout the stages of research and development, manufacturing, production, delivery, and the creation of demand, particularly for high-risk populations. Addressing global challenges like a pandemic crisis or a potential pandemic crisis exposes the world to shared vulnerabilities, necessitating international collaboration in response. During the pandemic, international collaborations were established, and existing ones were adapted to meet evolving needs. Additionally, we briefly discussed the Access to COVID-19 Tools Accelerator (ACT-A), which serves as a cross-agency partnership focused on providing access to COVID-19 tools, including MCMs. This underscores the critical emphasis on pandemic preparedness. In addition to addressing current challenges, it is imperative that our global efforts in pandemic preparedness and medical countermeasures remain vigilant and adaptable to the ever-evolving landscape of infectious diseases, including the potential emergence of "Disease X," a term used to represent unknown or unexpected pathogens that may pose future threats to humanity. The last five minutes of this episode includes a teaser of the Johnson & Johnson Bedquilline story of their treatment for multi drug resistant Tuberculosis that, post patent extension, the company agreed to waive their rights in certain regions where MDR Tuberculosis is highly prevelent. This will allow generics manufacturers to manufacture the drug and thus make it available at a lower price point to patients that need it most. But the story gets a little more interesting. The video mentioned is included in the full original article. Read the full article from the newsletter archives here: https://globalhealthconversations.substack.com/p/breakthrough-in-drug-patents-for And for follow ups, check out the later newsletters and subscribe for more news as this story unfolds: https://globalhealthconversations.substack.com/?utm_source=substack&utm_medium=web&utm_campaign=substack_profile Resources: Lancet Paper: Disease X: accelerating the development of medical countermeasures for the next pandemic Disease X - Comments on Disease X from Peter Sands, Executive Director of the Global Fund - Third party article: https://www.politico.eu/article/next-pandemic-disease-climate-change-peter-sands-global-fund/ | |||
| #8: Cancer in Africa: The Dual Burden of Disease | 20 Aug 2023 | 00:34:03 | |
This solocast episode dives into the dual burden of disease and its intersection with cancers in Africa. Across the African continent life expectancies are increasing. Advancements in primary care, strengthening of public health care systems and access to vital medical treatments have resulted in longer, healthier lives across the continent over the past few decades. Nonetheless, living longer makes one susceptible to acquiring an array of non-communicable diseases associated with longer life. The dual-burden of disease concept deals with the phenomenon of more and more emerging economies dealing with a combination of infectious diseases such as tuberculosis and malaria alongside the rising incidence of non-communicable diseases (NCDs) like cancers, cardiovascular diseases, and diabetes. This paradigm and its many nuances are demonstrated through a story. Thelma, a fictional character from Tanzania, illustrates the multi-faceted challenges faced by individuals dealing with both infectious and non-communicable diseases that typify the dual-burden of disease issue. And the story weaves itself through the episode. Discussing the rising cancer burden in Africa, emphasizing the significance of comprehensive cancer prevention and early detection programs we also addresses the increasing adoption of unhealthy lifestyles and their role in elevating cancer risks. And the insufficient access to cancer treatments that exists in too many parts of the continent due to financial constraints and inadequate healthcare systems as a critical challenge. Efforts to improve access and provide palliative care are explored, along with the role of research and innovation in addressing Africa's unique cancer challenges. Touching upon the importance of vaccination initiatives, government programs, and specialized treatment centers in addressing cancer. We underscore the need for investment in cancer research, local production of medical products, and the strengthening of biomanufacturing infrastructure to enhance healthcare accessibility as well as safe and reliable supply chains for Africa. The episode aims to spark awareness and conversations about the importance of targeted interventions, healthcare access, education, and research to address this complex public health issue. Resources: Sign up to the Fortnightly Newsletter on Global Health Conversations World Humanitarian Day https://www.un.org/en/observances/humanitarian-day Relevant blog articles:
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| #23: Mpox Update 18/08/2024 | 18 Aug 2024 | 00:19:37 | |
This fortnight's Newsletter WHO’s ACT-A and FIND convened a high-level meeting on August 15 to coordinate global efforts to address the outbreak. Key priorities include enhancing surveillance, developing a strategic research agenda, and coordinating global health responses. The WHO Global Preparedness Monitoring Board emphasized the importance of robust systems and medical countermeasures in the response, drawing on lessons from previous pandemics. Mpox, previously known as monkeypox, is a zoonotic viral disease characterized by fever, rash, pustules, and swollen lymph nodes. The current clade Ib is more virulent and transmissible, though the exact case fatality rate remains uncertain. The 2022 Mpox PHEIC was declared after a global outbreak affecting over 95,000 people in 115 countries, largely through human-to-human transmission. The PHEIC designation triggers a coordinated global response, including resource mobilization, increased surveillance, and public health measures. The response's success will depend on equitable distribution of medical resources and enhanced surveillance, particularly in underserved regions. WHO and Africa CDC emphasize the need for clear coordination, strategic implementation, and effective communication to manage the outbreak, with a focus on equity and access to diagnostics, vaccines, and therapeutics. | |||
| #7: Managing a Private Hospital in Nigeria, forming partnerships & addressing health disparities through the private sector (ft. Dr Miriambeth Asika) | 06 Aug 2023 | 01:08:00 | |
Dr. Asika Miriam is the Hospital Manager at Zenith Medical and Kidney Center. Miriam is a medical doctor and a healthcare management consultant with 7+ years of experience in clinical service delivery, healthcare operations management, health policy, planning & financing, strategic planning, and performance improvement gleaned from career endeavors in Eastern Europe, England, and Africa. Miriam is an alumnus of the Ivano-Frankivsk National Medical University, where she earned her MD (General medicine) degree. She also holds a postgraduate degree in International Health Management from Imperial College Business School. Miriam is passionate about African development and wants to improve healthcare delivery and strengthen the region's healthcare system. | |||
| BONUS: The Case of a Clinical Trial Catastrophe - The TGN1412 ‘Elephant Men’ Clinical Trial | 06 Aug 2023 | 00:34:33 | |
This episode is a little different. Today's episode is a story looking at the case of the TGN1412 CIinical Trial. A trial that went terribly wrong. This catastrophic event, now infamously known as the 'Elephant Man Drug Trial,' sent shockwaves rippling through the medical and pharmaceutical communities. TGN1412, a groundbreaking monoclonal antibody drug developed by TeGenero, a German biotech company, had held the promise of treating autoimmune diseases and leukemia. Paraxel, a prominent contract research organization, was responsible for conducting the Phase I trial, the critical first-in-human testing, within an independent clinical trials unit at Northwick Park. Prior to the trial, comprehensive clinical and animal testing, including studies involving non-human primates, had been diligently carried out. These preliminary tests had seemingly indicated no signs of safety issues. | |||
| #6: Addressing Life Expectancy through Nudges, Financial incentives & Disincentives (ft. Maria Kasimati) | 23 Jul 2023 | 00:58:07 | |
This episode is a must listen. 1. Nudges Versus Financial Incentives (abstract) (2023) | |||
| #5: CRISPR, Gene Editing, Access to Biotherapeutics & On-target approaches to the PhD journey (ft. Margareta Rybarikova) | 09 Jul 2023 | 00:55:17 | |
Subscribe to the Global Health Conversations Newsletter to be updated on the latest interviews and episodes 🤩 : https://globalhealthconversations.substack.com/?utm_source=substack&utm_medium=web&utm_campaign=substack_profile Margareta went on to complete a Master's degree in Genes, Drugs, and Stem Cells - Novel Therapies at Imperial College London, where she was elected as the Course Representative. For her MSc project, she explored AAV-mediated gene editing with small Cas9 nucleases for Huntington's disease. Her passion for genetic therapy led her to pursue a PhD at the CHUV, as part of the Lemanic Neuroscience Doctoral School in Lausanne. In her doctoral research, she is developing a CRISPR-Cas9 system for ATXN3 gene editing in Spinocerebellar ataxia type 3 (SCA3). A friend of the podcast, Margareta discusses her research, gene therapies as a frontier in tackling rare diseases, access to biotherapeutics and balancing life and science and scientific career paths. | |||
| #4: Revolutionizing Global Health with AI: Exploring Novel Approaches for Enhanced Health Outcomes | 25 Jun 2023 | 00:51:38 | |
Sign up to the newsletter: https://globalhealthconversations.substack.com/?utm_source=substack&utm_medium=web&utm_campaign=substack_profile One example discussed in this solocast episode revolves around vaccine policy. Predictive analytics, a technique that harnesses historical health data and other relevant factors, can play a pivotal role in anticipating disease outbreaks. By analyzing patterns in previous outbreaks, demographic information, climate data, and even social media trends, AI-powered predictive models can forecast the likelihood of an infectious disease spreading in a particular region. We talk about a hypothetical example of Dengue fever. This invaluable early warning system empowers policymakers to take proactive measures, allocating resources and implementing preventive strategies to curb the impact of the
In this latest solocast episode, we explore how analytics is revolutionizing decision-making across industries, uncover the challenges and ethical considerations associated with their implementation, and gain valuable insights into the future of this rapidly evolving field. | |||
| #3: How to Write Your Way to Success: Navigating Career Paths, Marketing in Healthcare & Life’s Unexpected Twists (ft. Maria Kasimati) | 11 Jun 2023 | 00:38:45 | |
In this episode of Global Health Conversations, I spoke to Maria Myrto Kasimati, MHCM, a scientific expert specialized in immunology and public health currently working for Havas Just:: as a Medical Writer. Maria has research experience in Ebola studies at University of Surrey’s faculty of Epidemiology, Immunology and Public health; and is an absolute firecracker passionate about democratizing healthcare access for all. Having pivoted her career path, Maria, known to her friends as Mary, is a true international and having earned her degrees in the United Kingdom, has worked in medical communications in London focusing on healthcare access. Today she is a specialist medical writer working closely with the pharmaceutical industry. We discuss career paths, healthcare access and medical writing. Have you wondered how to harness your scientific background into science-driven education and medical writing? This episode is a must-listen for any young scientist asking yourself the question we all ask ourselves: What do I do next? | |||
| #2: Let’s Talk Obesity in the UK - Causes and Consequences | 06 Jun 2023 | 00:21:25 | |
The consequences of rising obesity are far-reaching. It increases the risks of chronic conditions like diabetes, heart disease, and certain cancers. The strain on healthcare systems and associated economic costs are substantial, underscoring the urgency to address this issue. In this solocast episode, we explore the causes and consequences of the rise in obesity incidence in the United Kingdom. With a focus on facts, we uncover the multifaceted factors contributing to the issue and its implications on individuals and communities. | |||
| #1: Universal Health Coverage: No-one Left Behind & Financial Protection (Part 1) | 06 Jun 2023 | 00:19:54 | |
Imagine a world where quality healthcare is accessible to all individuals and communities, without the burden of financial hardship. This is the essence of universal health coverage, a concept that has gained significant attention in recent years and lies at the heart of the SDG Agenda for health. In this three-part series, we delve into the importance of UHC and its different components, exploring how it can transform healthcare systems and improve people's lives. At the heart of UHC lies the idea of providing comprehensive health services to everyone: leaving no one behind. http://apps.who.int/iris/bitstream/handle/10665/361229/9789290234760-eng.pdf?sequence=3 | |||
| #0: Introduction to Global Health Conversations Podcast | 04 Jun 2023 | 00:02:30 | |
Global health conversations is a podcast dedicated to exploring the most pressing issues in public health today from the fields of science, medicine, health economics, global public health and development. New episodes and interviews every two weeks. | |||
| #22: Project 2025 Impact on Healthcare, Women's Health and Regulation | 21 Jul 2024 | 00:34:31 | |
Subscribe here to the Global Health Conversations Newsletter 02:00 - Preamble 02:56 - Project 2025 High Level Overview 08:55 - Point 1: Changes to Medicaid, Medicare & Lower income patients 14:20 - Point 2: Impact on Public Health & the new role of the CDC 17:06 - Point 3: Food and Drug regulation proposed changes 22:05 - Point 4: Any comments on Safety, Guns and Ammunition? 24:09 - Point 5: Restrictions around Women’s health, access to birth control & more | |||
| BONUS: Real Water - Water gone wrong! A Public Health Scandal | 23 Jun 2024 | 00:23:24 | |
In this BONUS episode, we delve into the true crime-style medical scandal of Real Water. The company’s negligence led to severe health issues, including acute liver dysfunction in consumers like Megan Fisher’s son, Tommy. Real Water’s aggressive marketing of its unproven E2 technology claimed extraordinary health benefits, but the FDA found a potentially toxic compound in the water, that caused acute hepatitis in some consumers. The ensuing lawsuits and investigations revealed a lack of quality control and corporate greed. This episode underscores the need for stringent regulatory oversight and vigilance in scrutinizing health claims to protect consumers from similar dangers. | |||
| #21: Philippines: Twelve Minute Health System Summary | 23 Jun 2024 | 00:11:44 | |
In this mini solo episode, we take a high level look at Philippines' health system. | |||
| #20: The Profitability of Skinny - How Semaglutides made Novo Nordisk Europe's most profitable company | 09 Jun 2024 | 00:25:11 | |
In this episode, we explore the economics of thinness and the phenomenal rise of GLP-1 receptor agonists in the weight loss market. Novo Nordisk, the Danish pharmaceutical company behind Ozempic and Wegovy, has become Europe's most profitable company, surpassing even the luxury giant LVMH. We delve into the social and economic capital associated with thinness, examining how societal attitudes toward body image drive the profitability of weight loss drugs. We also break down the science behind GLP-1 receptor agonists, including their mechanisms and market dynamics. We'll discuss the first-in-class drugs like Saxenda, and best-in-class competitors such as Trulicity and Mounjaro. Novo Nordisk’s strategic business moves, including their significant investment in R&D and marketing, have cemented their market dominance. Additionally, we highlight the broader implications of these drugs on global health and their potential for continued growth in a competitive landscape.
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| #19: Drug Licensing and the Pandemic Accord | 28 Apr 2024 | 00:39:37 | |
In this week’s episode, we look at Colombia's recent move in issuing its first compulsory license. The country challenged ViiV Healthcare's monopoly on their patented drug, dolutegravir, an HIV therapeutic, in an attempt to open doors for affordable generic versions and thus improve accessibility & affordability. We explore the nuances of licensing mechanisms - voluntary agreements & compulsory licenses. We discuss their impact on public health and innovation, drawing parallels with past instances. We also delve into the proposed European Union-wide Compulsory Licence and industry perspectives on intellectual property. Hard subject here - and as someone who started out in Pharma I find it hard to put full advocacy behind non-market driven mechanisms. But what does the data say?
3. ViiV HEALTHCARE STATEMENT ON COMPULSORY LICENCE FOR DOLUTEGRAVIR IN COLOMBIA https://viivhealthcare.com/hiv-news-and-media/news/company-statements/viiv-healthcare-statement-on-compulsory-licence-for-dolutegravir-in-colombia/ 5. Draft WHO Pandemic Agreement - March 2024 - https://apps.who.int/gb/inb/pdf_files/inb9/A_inb9_3-en.pdf 6. Proposal for article 11b - https://www.southcentre.int/wp-content/uploads/2024/04/SV261_240423.pdf 7. Paper - Access to medicines after TRIPS: Is compulsory licensing an effective mechanism to lower drug prices? A review of the existing evidence - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468182/ 8. IFPMA non comprehensive list of voluntary licenses and non-assert declarations: https://www.ifpma.org/wp-content/uploads/2023/01/i2023_2010_07_28_IFPMA_Statement_VoluntaryLicensing_NonAssert_28Ju.pdf 9. How The EU Prepares For the Next Global Pandemic Domestically: An Examination of the Union Compulsory Licence https://genevahealthfiles.substack.com/p/how-the-eu-prepares-for-the-next?utm_source=post-email-title&publication_id=79396&post_id=143395445&utm_campaign=email-post-title&isFreemail=true&r=1zo8cv&triedRedirect=true&utm_medium=email | |||
| #18: Prioritising Oral Health in Public Health (ft. Ema Prohić) - Part 2 | 14 Apr 2024 | 00:48:43 | |
This is Part 2 of our 2 Part interview. | |||
| #17: Prioritising Oral Health in Public Health (ft. Ema Prohić) - Part 1 | 31 Mar 2024 | 00:59:28 | |
On this episode I interview Ema Prohić and we discuss the true cost of oral health. Drawing on her experience in different health systems, we discuss the financing of dental procedures, dentist fear and how to avoid the most common oral health pitfalls. We also discuss a public health project that I lead back in 2020 with the Ministry of Health Qatar and PHCC wherein she focussed on integrating oral health into a primary care program. This is Part 1 of a super conversation this season. And you won't want to miss it. | |||