Cutting Edge Health: Preventing Cognitive Decline – Détails, épisodes et analyse

Transcript with time code:  https://cuttingedgehealth.com/wp-content/uploads/2024/11/Dr.-Paul-Savage-Unveils-Pioneering-Plasma-Exchange-Protocol_-Reverses-Toxins-Inflammation.pdf

In this insightful discussion, uncover the impact of rising toxin levels over the past 40-50 years with Paul Savage, MD. He believes most heavy metals and pesticides we encounter today didn’t even exist a few decades ago. Shockingly, 75% of them may be lurking in your own home.

As a renowned expert in functional medicine, Dr. Savage delves into the challenges our bodies face in eliminating them and the role of therapeutic plasma exchange in supporting detoxification. He is offering a free guide book (https://info.mdlifespan.com/cuttingedgehealth) filled with details on toxins, potential health conditions related to them and available methods for their removal.

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At 37 years old, Dr. Paul Savage was a successful ER/trauma physician. But he was unhealthy, weighed 270 pounds, smoked cigarettes, was tired, anxious, and unwell, and  had high cholesterol, high blood pressure, pre-diabetes, and stress.

Rejecting the conventional approach of more medications, his curiosity and  determination led him to explore various treatments and lifestyle changes, transforming his life and career through precision medicine.  

Twenty-five years later, he’s an advocate for combining traditional and integrative  medicine, focusing on an evidence-based approach that treats patients as partners. Dr.  Savage embraces a continuous pursuit of knowledge and integration of the latest  medical advancements into his practice, with several board certifications, including  certifications from the Stem Cell Fellowship, Integrative Metabolic Medicine, and the  American Academy of Anti-Aging Medicine. Not to mention, he built over 50 clinics  across the United States and literally wrote the code for the industry standard software  that has helped millions of patients.  

Dr. Savage is the founder and current CEO of MDLifespan in Chicago. His latest endeavor of the  patented PlasmaXchangeTM protocol is the culmination of years of expertise — it's  poised to be the defining moment of his career, a transformative movement that will  reshape the future of medicine as we know it.  

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Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast

Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan and Maria on the Cutting Edge Health team!

#Lifestyle #Brain #BrainHealth #MedicalBreakthrough #CognitiveHealth  #DiseasePrevention #ProactiveHealth #FunctionalMedicine #HolisticHealth #alzheimer #neuroscience #neurologist

Transcript with time code: https://cuttingedgehealth.com/wp-content/uploads/2024/10/Transcript-42-Dr-Mitch-Clionsky-1.pdf

This podcast episode features Dr. Mitch Clionsky, a neuropsychologist who specializes in preventing cognitive decline and dementia, and who has treated over 30,000 patients throughout his career. He discusses his book Dementia Prevention: Using Your Head to Save Your Brain, offering key insights into how dementia is a neurological disorder, not just a psychiatric condition. Dr. Clionsky emphasizes that dementia is not inevitable, even if it runs in your family—up to 50% of cases can be prevented with lifestyle changes. He highlights the importance of identifying risks like sleep apnea, hearing loss, and gum disease, and explains how treating these issues early can help maintain cognitive health. In the “Links and Resources” tab below are four sleep-apnea-related papers Dr. Clionsky refers to in the podcast. He also talks about the benefits of exercise and starting prevention early. Dr. Clionsky encourages listeners to assess their health habits and take proactive steps to reduce their dementia risk, providing practical advice and tools to help them stay mentally sharp as they age.

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Mitchell Clionsky, PhD, is a board-certified neuropsychologist who specializes in evaluating and treating patients with cognitive impairment, dementia, ADHD, and traumatic brain injury. 

He has a private practice, Clionsky Neuro Systems, Inc., based in Springfield, Massachusetts.  He is an experienced public speaker, podcast guest, and workshop presenter for general and professional audiences. 

With Emily Clionsky, M.D., he authored Dementia Prevention: Using Your Head to Save Your Brain. 

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Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast

Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan and Maria on the Cutting Edge Health team!

The interview with Dr. Yoshi Rahm on the Cutting Edge Health podcast covers topics on enhancing cognitive health. Dr. Rahm discusses his personal journey influenced by his family's health issues and his integration of holistic practices into medicine. He delves into Extracorporeal Blood Oxygenation and Ozonation (EBOO) therapy for immune system boosting and reducing inflammation. Additionally, Dr. Rahm explains the use of methylene blue for cognitive improvement, its safe dosage, and potential side effects. He emphasizes the importance of lifestyle modifications, including diet, exercise, and community for overall cognitive health. The concept of structured water and its benefits for body energy and hydration is also discussed.

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Dr. Yoshi Rahm finds meaning and joy in ever learning to be present with himself and whomever he is with in the moment, especially with his family, friends, and patients.  Much of his life's pursuits stem from growing up far outside of a small town in Northern California.  His simple upbringing, which included living without electricity, TV, or phone, gave him an early appreciation for healthy living.  The suffering of unwell family members was a big driver for Dr. Rahm to pursue healing in the form of becoming a family physician. 

After residency at Glendale Adventist Medical center, where he received the two highest distinctions: “Resident Teacher Award” as presented by the faculty and “Resident of the Year Award” as recognized by the staff, Dr. Rahm then went on to become an Attending Physician teaching at the same residency program and also founded Oasis Family Medicine. 

With the support of incredible team members at Oasis Family Medicine, they are able to serve people from around the globe who have a wide variety of medical conditions in a compassionate and effective manner, combining the best of allopathic western medicine in conjunction with an integrative and holistic healing approach.  He thrives on learning and then using that learning to teach others how to be their own greatest healers.

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Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast

Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan and Maria on the Cutting Edge Health team!

In this podcast interview, Dr. Lisa Barnes discusses her work in cognitive neuropsychology and efforts to diversify Alzheimer’s disease research by including Black Americans. With a background from the University of Michigan and UC Davis, Dr. Barnes joined Rush Medical College in 1999 and has been leading the Minority Aging Research Study since 2004, focusing on brain health within the Black community.

Dr. Barnes initiated the Minority Aging Research Study to address the underrepresentation of Black individuals in dementia research, overcoming trust barriers rooted in historical mistreatment and increasing awareness about Alzheimer’s in the Black community. The study includes over 800 participants and promotes understanding of Alzheimer’s by offering community-based education and recruitment, advocating for brain donation, and examining the link between discrimination and cognitive health. Dr. Barnes highlights the complexity of Alzheimer’s disease, noting that social determinants play a significant role in brain health and discussing genetic findings that challenge assumptions about the disease’s prevalence in Black Americans. Although some research suggests that there may be twice the incidence of Alzheimers in Black communities, Dr. Barnes notes that when studies follow people over time, there doesn’t appear to be any faster rate of decline in Black people than White people. You would expect to see a faster rate of decline if there’s more Alzheimer’s. “People thought Alzheimer’s disease is a White person’s disease, or they thought we’re supposed to lose our memory when we get older. There’s nothing you can do about it. I think we have to debunk some of those myths,” she says.

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Lisa L. Barnes, PhD is the Alla V. and Solomon Jesmer Professor of Gerontology and Geriatric Medicine and a cognitive neuropsychologist within the Rush Alzheimer’s Disease Center at Rush University Medical Center. She is also the Associate Director of the Rush Alzheimer’s Disease Research Center. She received her PhD from the University of Michigan in biopsychology and completed a postdoctoral fellowship in cognitive neuroscience at the University of California, Davis. She has been a faculty member at Rush Medical College since 1999. Dr. Barnes has received many NIH grants and has published over 300 manuscripts. Her research interests include disparities in chronic diseases of aging, cognitive decline, and risk factors for Alzheimer’s disease. She is the Principal Investigator of the Minority Aging Research Study (MARS), which has been funded by NIA since 2004, and the Clinical Core Leader for the Rush African American Clinical Core. She advocates for recruitment of under-represented groups into clinical studies and has received many awards and fellowships.

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Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan and Maria on the Cutting Edge Health team!

For those who want to truly assess your genetic risk of Alzheimer’s, IntellxxDNA has created a tool to help.  With a simple cheek swab, this Austin, Texas based firm can provide you and your health care provider with a personalized genetic report that goes much deeper than what you’ll get from most genetic testing. For those with the APOE-4 Alzheimer’s gene there are other genes to know about that either can dramatically increase or decrease your risk of developing the disease.  Having this information allows one to take action early to prevent its onset.

Sharon Hausman-Cohen, MD is our guest for this podcast episode. She and her co-founder, Carol Bilich, developed IntellxxDNA. Their research is focused on making genetics actionable and understandable for each individual patient and their provider.

There are dozens of gene variants that can interact with ApoE4 and act as gene modifiers that decrease or increase ApoE4 dementia risk. Some of these include:

• TOMM40 and ApoC1 - If no TOMM40 or ApoC1, the risk of ApoE4 is lowered to very close or equal to ApoE 3/3.

• BCHE–K variant - This variant, when present, makes it more likely for amyloid to form tangles.   Only about 35% of people have this variant. Being part of the 65% of individuals who do not have this variant or being "BCHE-K variant" negative halves the risk of ApoE4. Conversely, being BCHE - K variant positive doubles the risk.

•There are other variants in detox pathways, hormone receptor pathways and inflammatory pathways and more that also interact with ApoE4. 

Listen to learn more.

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Dr. Sharon Hausman-Cohen is the Chief Medical Officer and co-founder of IntellxxDNA™.  She received both her master’s degree and medical degree from Harvard Medical School. She is a fellow of the American Academy of Family Medicine and a diplomate of the American Board of Integrative Medicine. Dr. Hausman-Cohen has been in the field of integrative medicine for over 25 years. She is the co-author of many publications relating to genomics including three that focus on cognitive decline and two that focus on autism.  She is also the primary author of a precision medicine textbook chapter on genomics and neurodegenerative diseases and a chapter in a book published by Frontiers in Neuroscience and Aging relating to frontiers in dementia treatment.  She and her co-founder developed IntellxxDNA as an answer to an unmet need in the medicine community; the need for an accurate, evidence-based genomics tool geared at helping physicians practice personalized medicine.

They envisioned and created a tool that could help identify root causes of cognitive decline, autism, environmentally acquired illness, and common chronic illnesses such as heart disease, diabetes, depression, anxiety and obesity.  IntellxxDNA’s research has focused on making genomics actionable and understandable, so that clinicians know how to address these genomic factors in a precision way. IntellxxDNA is being used as part of 3 IRB approved clinical trials relating to helping individuals with memory concerns and early dementia as well as children with autism and other complex illnesses.  It is also being used as part of medical decision-making by physicians across the country.

Dr. Hausman-Cohen loves combining her passion for science and medicine and using her scientific mind to integrate large amounts of complex data. She also enjoys teaching and has taught extensively across the country at conferences for physicians as well as for community members. Dr. Hausman-Cohen is the co-founder of Resilient Health which is her patient facing practice in Austin, TX.

For access to publications, podcasts and videos see:  IntellxxDNA.com

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Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast

Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan and Maria on the Cutting Edge Health team!

Research at Boston University has led to the discovery of a non-invasive method to diagnose Alzheimer's.  This opens the door in the coming years to possibly detecting the disease in its early stages, decades before real symptoms appear. 

Manju Subramanian, MD and her team found that proteins in eye fluids are providing this window to the brain. These eye fluids are confirming pathological brain conditions like dementia in the Alzheimer's form. Until now, MRIs and lumbar punctures were the tools to aid the clinical diagnosis of Alzheimer's, but that has meant late detection when the disease is already in place. Alzheimer's is not actually confirmed until after death and a post-mortem examination of the brain is done. 

"We know that patients with eye disease tend to be an at-risk population for dementia. Patients with macular degeneration, glaucoma and diabetic retinopathy, those are the three big ones," says Subramanian.

The potential of an eye fluid exam at an optometrist's office is ideal as it's non-invasive and not expensive.  But, it is still several years out before potentially becoming commonplace.  More research is needed. Still to be determined in future research is just how early eye fluid proteins become abnormal when dementia is developing.  

"As they say, the eye is the window to the soul.  It is also very much the window to the brain," says Subramanian.

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Manju Subramanian is an Associate Professor in Ophthalmology and Vice-Chairman of Faculty Affairs. She is an ophthalmic surgeon specializing in Vitreoretinal Disease and Surgery, and is in academic practice at Boston Medical Center. She also sees patients at the Dedham Ophthalmic Consultants. Her primary areas of clinical interest include medical and surgical management of diabetic retinopathy, age-related macular degeneration, retinal detachments, hereditary retinal diseases, ocular inflammation, and ocular trauma. Dr. Subramanian graduated from the University of Missouri School of Medicine and completed her residency at the University of Kansas Medical Center in 2002. She completed a fellowship in Vitreoretinal Disease and Surgery at Tufts University School of Medicine and Ophthalmic Consultants of Boston in 2004.

Dr. Subramanian’s research interests include the study of eye-based biomarkers for Alzheimer’s Disease (AD), age-related macular degeneration, diabetic retinopathy, and the role of anesthesia in eye surgery. She was Principal Investigator for the first head to head clinical trial comparing the use of bevacizumab and ranibizumab in the treatment of age-related macular degeneration, and she is currently the Principal Investigator for a study assessing the role of oral sedation in eye surgery. She is also a recent recipient of an R03 Grant Award by the National Institutes of Aging as the Principal Investigator of a study looking at protein biomarkers for AD in the eye.

In her role as Vice-Chairman of Faculty Affairs at Boston University Eye Associates, she works in a supportive role in the professional and career development and engagement of the clinical faculty. Prior to 2017, she served as the Vice-Chairman of Clinical Services for 8 years. She serves on several institutional committees, including the Women’s Leadership Advisory Council, the Boston University Medical Group (BUMG) Research Committee, the BU School of Medicine Promotion Criteria Working Group, and also serves as Chair of the BUMG Professional Development Committee. She additionally serves on national committees, such as the International Meetings Committee for the American Academy of Ophthalmology (AAO), the Diversity Initiatives Committee for the Association for Research in Vision and Ophthalmology (ARVO), and a Special Emphasis Panel for a Study Section with the National Institutes of Health.

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Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dementia can be prevented, and Kat Toups, MD knows this firsthand.  Dr. Toups is a San Francisco Bay Area psychiatrist, but she is also an accomplished researcher who led investigations in 20 extensive clinical trials focused on Alzheimer's and MCI (Mild Cognitive Impairment). While working in this area, she developed dementia herself, and by using functional medicine, she reversed her own decline. 

Dr. Toups thrives on helping people. She partnered with Dale Bredesen, MD on a clinical trial using functional medicine, often called precision medicine, where 84% of the study patients with MCI and early dementia had improvements as shown on their MRI brain scans and other cognitive assessments. The study’s results were published in the Journal of Alzheimer's Disease in August 2022:  Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project.

Following this success, Dr. Toups has now launched a much larger clinical trial in six cities around the United States. Participants must live within an hour’s drive of one of these locations:

Walnut Creek (San Francisco East Bay), CA

San Rafael (San Francisco/Marin County), CA

Sacramento (El Dorado Hills), CA

Miami (Hollywood), Florida

Nashville (Brentwood), Tennessee

Cleveland (Rocky River), Ohio

For more information: www.dementiareversaltrial.com

Dr. Toups says dementia happens for multiple reasons. It doesn’t just come out of nowhere, but likely has been slowly building for more than a decade.  Dr. Toups says it’s critical to search for contributing factors at the earliest opportunity if you want success in stopping or reversing disease progression. In this interview, she elaborates on the importance of partnering with a functional medicine doctor to do this work.  Some of the core contributors to cognitive problems might be inflammatory load in the body, heart health, hormone levels, exercise, stress, sleep, toxins, and infections amongst many other factors.

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Kat Toups, M.D., DFAPA, IFMCP is a functional medicine psychiatrist at Bay Area Wellness in Walnut Creek, CA. Dr. Toups is a distinguished fellow of the American Psychiatric Association (the highest honor bestowed by the APA), board certified by the American Board of Psychiatry and Neurology, and previously boarded in geriatric psychiatry.

Dr. Toups is a former assistant professor of psychiatry at UC Davis, where she was the inpatient residency training director, and later the owner/medical director of Bay Area Research Institute, a clinical trials research center in Lafayette, CA. After serving as the principal investigator on over 100 clinical trials for 12 years, including 20 failed trials for Alzheimer's drugs, she realized that the elusive cure for brain and psychiatric illness was not going to be found in a pill.

She embarked on an intensive course of study (initially sparked by a quest to heal her own serious autoimmune disease) to learn functional and nutritional medicine and completed her training for the Institute for Functional Medicine Certification in October 2013.

Dr. Toups practices functional medicine psychiatry, which seeks to discover the underlying causes of inflammation (like diet/nutrition, lifestyle, genetics including MTHF/Methylation/Sulfation/Detoxigenomic genetic polymorphisms, GI health including food allergies and dysbiosis, toxin exposure, chronic infections, and biochemical abnormalities) that can all be contributors to problems with psychiatric symptoms and/or cognition difficulties. Detection and correction of these problems can result in the resolution of the psychiatric symptoms, rather than just providing a band-aid by only prescribing psychiatric medications without addressing the underlying causes of the problem.

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Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Eric Larson is a leading expert on aging and dementia and one of the creators of a massive living lab studying the brains of 5000 Seattle residents as they age over decades. The research is called the Adult Changes in Thought (ACT) Study. Dr. Larson is optimistic when it comes to preventing the devastating disease, but not because miracle medicines might be on the horizon. Instead, he believes Alzheimer’s and other types of dementia are directly impacted by the lifestyle choices individuals make. He’s finding people are increasingly paying attention to those lifestyle issues and doing the right thing for their health.

In fact, as an example, he says, the closest thing to a magic pill for reducing the risk of dementia is probably exercise.  But that is just one of the 12 modifiable risk factors to prevent the disease. Larson speaks to the dozen modifiable risk factors that were presented in a 2020 report of the Lancet Commission and they include:  less education, hypertension, hearing impairment (between the ages 45-65 hearing loss is the biggest modifiable risk factor), smoking, obesity, depression, physical inactivity, diabetes (type 2 leads to a two-fold increased risk of developing AD), low social contact, excessive alcohol consumption, traumatic brain injury, and air pollution.

“There is no inevitability about this condition,” he says of the loss of cognitive functioning. “I was reading the numbers. There's a 1/3 drop from 2000 to 2016 in the rates of dementia in North America and Europe. We have reached a point where people are better educated, socio and economic indicators have improved. We're not doing the same stuff our parents were doing as far as health. We realize we need to exercise, and not smoke, and not drink a bunch of alcohol.”

On the other hand, Dr. Larson worries that dementia is increasing in less-advanced, industrializing societies that adopt some of the unhealthier aspects of the Western lifestyle. 

Some of the choices that people can make to diminish the risk of Alzheimer’s, besides engaging in physical exercise, are controlling weight and blood pressure; treating or protecting against diabetes; quitting smoking; moderating alcohol consumption; and addressing hearing loss and perhaps even vision impairment. 

"A lot of the things that reduce the risk of dementia and Alzheimer's disease are the things that improve health and well-being in older people,” points out Dr. Larson, who recently retired. But individuals should not wait until they approach old age to adapt to a healthy lifestyle. The earlier they begin, the more likely they are to diminish the chances of losing cognitive function.

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Dr. Eric B. Larson was executive director of Kaiser Permanente Washington Health Research Institute (KPWHRI) and vice president for research and healthcare innovation at Kaiser Foundation Health Plan of Washington. A general internist, he was a professor of medicine at the University of Washington in Seattle. He recently retired from full-time work, but continues to be active in the field of geriatrics and works part time at the University of Washington’s Department of Medicine as a professor of medicine.

Dr. Larson began at the University of Washington as a fellow in 1975 after graduating from Harvard Medical School. He served as medical director at the University of Washington Medical Center and was associate dean for clinical affairs from 1989 until 2002.  Dr. Larson joined Group Health (now Kaiser Permanente) in 2002 to lead the Center for Health Studies. His research on aging includes a longstanding collaboration between Kaiser Permanente Washington and the University of Washington called the Adult Changes in Thought (ACT) Study. With colleagues from University of Washington and Group Health, he received a demonstration grant from the National Institutes of Health to establish a model Alzheimer’s disease registry in 1986.  This morphed into the landmark Adult Changes in Thought study with the establishment of the initial cohort of 2581 randomly selected volunteers who joined the study 1994-96. The cohort has doubled since then and is one of the longest continuous studies on aging and dementia in the world.

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Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Keeping your liver clean is yet another way to boost your cognitive longevity and enhance the likelihood that your brain stays sharp as long as possible. Though many people pay little attention to the liver and have scant knowledge of what it does, this vital organ performs many critical roles in enabling the body to continue functioning. Most significantly, it rids the bloodstream of harmful toxins.  

“Your liver is vitally important,” explains Dr. Lisa Broyles. “It removes toxins and chemicals that are dangerous for us from our blood and gets rid of them.”

Dr. Broyles, a certified functional medicine doctor who is specially trained in preventing and reversing cognitive decline, says that people should pay attention to the liver and take steps to detoxify the organ if it is struggling to perform its many functions. Among those functions, besides detoxifying the blood stream, are producing and regulating the level of cholesterol, regulating sex hormones, storing sugar when the body needs it, tending to the body’s immune health, and guarding against blood clotting.  

When the liver is having difficulty in its effort to remove bodily toxins, it can lead to such problems as migraine headaches, autoimmune disease, cancer, lupus, and arthritis.

The liver must be clean, Dr. Broyles says, if it is to effectively do its job.

“I do think that every six months, ideally, everyone should do a liver and gallbladder flush, and followed by some colon hydrotherapy, both before and after,” she recommends. Dr. Broyles says that a number of companies offer liver cleansing approaches and kits.

She talks about three phases of liver detoxification - oxidation, conjugation (making toxins more water soluble so they excrete into the intestines and leave the body), and transportation where toxins are broken down (to assure a healthy gallbladder).  

The food you eat and the medicines and vitamins you take can all enhance — or in some cases hinder — the the way the three phases clean the liver of its toxins. For instance, Tylenol can shut down the process of liver conjugation, according to Dr. Broyles. She points out that genetic make-up also plays a role in liver detoxification; each person is different and testing can help determine the right steps to take in cleaning the liver.   

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Dr. Lisa Broyles, MD, is trained in the Bredesen Protocol, a personalized program to prevent and reverse cognitive decline. It is estimated that nearly 50 million currently living Americans will die of Alzheimer’s disease if effective prevention and reversal are not implemented–almost 100 times more than have died of COVID-19. Mainstream medicine would have you believe that it can’t be prevented, is untreatable, and progressive, with most patients not surviving beyond three to eleven years post-diagnosis.   But we are learning that the disease is a pathology of multiple causes that is preventable and even reversible in the early stages through the kind of holistic and individualized approach prescribed by the Bredesen Protocol.   A certified functional medicine doctor with an interest in holistic/integrative medicine, Dr. Broyles is transforming medical care in rural North Carolina. Addressing the underlying causes of disease rather than simply treating symptoms, Dr. Broyles uses a systems-oriented, holistic approach that engages both patient and practitioner in a therapeutic partnership. The result has been a palpable rise in health IQ and wellness in the community she serves.   “People are hungry for this kind of patient/physician collaborative care. They want to take charge of their well-being. They want to feel empowered. Too often, though, the insurance system in America limits choices for physicians and patients alike. Functional medicine represents a fundamental paradigm shift from symptom suppression to an integrative body/mind approach to optimal health,” said Dr. Broyles.   Hoping to help more people than her limited practice can accommodate, Dr. Broyles is reaching out to her community through the Cutting-Edge Health podcast and other platforms.   Having graduated from the Brody School of Medicine at East Carolina University and completed her three-year residency at the University of Tennessee in Knoxville, Dr. Broyles is currently a family practitioner in Saluda, North Carolina.   For the past several years, she served patients at urgent care and occupational medicine centers in South Carolina and Tennessee. Prior to this, she was medical director for the East Tennessee Spine and Nerve Center in Chattanooga and the Johnson City Tennessee Downtown Clinic. Dr. Broyles graduated from Brody school of medicine at East Carolina University in Greenville North Carolina and obtained her functional medicine certification from Functional Medicine university in Greer South Carolina.   *****

Cutting Edge Health podcast website: https://cuttingedgehealth.com/

Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast

Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756

Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

If you aspire to live a long life, don’t wait until you are 60 to pursue it, advises Dr. Jeffrey Galvin, director of the Vitality Medical Wellness Institute  North Carolina. The earlier you begin living a lifestyle aimed at longevity, the more likely you are to reach your 90’s and beyond in health, he suggests. 

“How do we build vibrant, healthy 90-year-olds?” he asks. “We start with 30 and 40-year-olds, maybe 50-year-olds.”

Galvin anticipates technologies, just over the horizon, that will radically extend human life. And current research (on mice and other animals) seeks to remove a body’s degraded cells and replace them with younger ones as a vehicle toward longevity.

But Dr. Galvin’s practice, the Vitality Medical Wellness Institute in Charlotte, NC, is not just trying to enable patients to live longer but also to enable them to be healthier as they age. “The idea is you want to stay healthy and performing really well for a long time,” he says.

Dr. Galvin wants to optimize peoples’ performance as long as possible and lessen the decline that often precedes death. He thinks it better to live to 90, and have just two years of decline rather than endure decades of decline even while living longer.

Another reason to strive for a healthy life sooner rather than later, he says, is that the life-prolonging technologies to become available in a few years won’t be accessible to the unhealthy. But,“If you're 75 and you're in top shape, then you're going to absolutely be eligible for those therapies."

He laments that most doctors treat disease and symptoms to manage decline but don’t show interest in patients’ overall health. He doesn’t blame the doctors themselves — “The system is not set up for you to be healthy,” he asserts.

Major causes of death — strokes and heart attacks, cancer, Alzheimer’s — must be minimized in advance. That entails evaluating family history and personal risk factors, testing for disease markers and planning how to uproot these potential seeds of death. “It really is important to do this testing and look at people's baseline health,” Dr. Galvin says. "We reverse chronic disease, because you can't really optimize until you get rid of all the underlying problems.”

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Jeffrey Galvin is the medical director and founder of Vitality Medical Wellness Institute. He is board-certified in emergency medicine and obesity medicine.  He served as a major in the United States Air Force, specializing in trauma and emergency care.  After completing his military service, he settled in Concord, NC, with his wife and three children. With over 25 years’ experience working in some of the busiest emergency departments in the country, he has cared for over 50,000 emergency and trauma patients.

Dr. Galvin has extensive training and experience in functional medicine, hormonal optimization, fitness, nutrition, genomics and epigenetics, and brain peak performance.  He is an expert biohacker experienced in nootropic use, peptide therapies, heart rate variability training, and sleep hacking.  His goal is maximizing human performance, reversing chronic disease and optimizing overall health.

Dr. Galvin founded Vitality Medical Wellness Institute in 2010.  It was born out of frustration with modern medicine’s focus on treating symptoms of illness, not the underlying causes. The Institute seeks to change the paradigm by which the medical establishment trains doctors to treat chronic medical problems with medication while ignoring the root origins of disease.  Dr. Galvin believes that by focusing on nutrition, fitness, hormonal optimization, and permanent lifestyle changes, health can be optimized. By utilizing this approach his patients are able to reverse chronic medical conditions, lose weight and maximize performance. At the same time risk of future disease is minimized.

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