Interview with Robert Bals, MD, PhD, author of Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections: A Phase 2 Randomized Clinical Trial, and Dan H. Barouch, MD, PhD, author of A Novel Approach for Preventing Respiratory Virus Infections. Hosted by Eve Rittenberg, MD.

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Interview with Churl-Su Kwon, MD, MPH, author of Association of New-Onset Seizures With SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Hosted by Cynthia E. Armand, MD.

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JAMA Health Forum Editor John Ayanian, MD, and Deputy Editor Melinda Buntin, PhD, discuss with Sandra B. Nelson, MD (Massachusetts General Hospital, Boston), her JAMA Health Forum study of transmission of SARS-CoV-2 in schools in Massachusetts during 2 different phases of the COVID-19 pandemic. She found transmission rates were very low but varied by district and the availability of vaccines.

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Interview with Carlos del Rio, MD, author of Long-term Health Consequences of COVID-19

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Roy H. Perlis, MD, MSc, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study assessing admission laboratory and comorbidity features associated with critical illness and mortality risk among patients hospitalized with coronavirus disease 2019 (COVID-19) across 6 Eastern Massachusetts hospitals.

Read the article here: https://ja.ma/384dBkt. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open.

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JAMA Pediatrics Editors' Summary by Dimitri Christakis, MD, MPH, Editor in Chief, and Frederick Rivara, MD, MPH, Editor in Chief of JAMA Network Open for the November 2, 2020 issue.

Tim Uyeki, MD, chief medical officer for the Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), discusses how the COVID-19 pandemic may affect the 2020-2021 influenza season.

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Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the latest developments in the COVID-19 pandemic, including the continued importance of nonpharmaceutical interventions (masking, handwashing, physical distancing) for managing rising case numbers in the US and globally. Recorded October 28, 2020.

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Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions

Paul A. Offit, MD, of the Children's Hospital of Philadelphia, returns to JAMA's Q&A series to provide an update on progress in COVID-19 vaccine development. Recorded October 27, 2020.

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Large Meta-analysis Digs Into Obesity’s COVID-19 Risks; As Their Numbers Grow, COVID-19 “Long Haulers” Stump Experts; Telephone Visits Surge During the Pandemic, but Will They Last?

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Large Meta-analysis Digs Into Obesity’s COVID-19 Risks

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Telephone Visits Surge During the Pandemic, but Will They Last?

John S. Brownstein, PhD and Douglas L. Kriner, PhD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study evaluating the factors associated with US adults’ choice of and willingness to accept a hypothetical COVID-19 vaccine.

Read the article here: https://ja.ma/3e0Rz3i.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Aaron L. Baggish, MD, and Jonathan H Kim, MD, authors of Coronavirus Disease 2019 and the Athletic Heart: Emerging Perspectives on Pathology, Risks, and Return to Play, and James E. Udelson, MD, author of Return to Play for Athletes After Coronavirus Disease 2019 Infection—Making High-Stakes Recommendations as Data Evolve

Rochelle P. Walensky, MD, MPH, of Harvard Medical School and Massachusetts General Hospital returns to JAMA's COVID-19 Q&A to provide an update on developments in the pandemic. She is a signatory of the recent John Snow Memorandum emphasizing the importance of public health interventions to manage the spread of COVID-19. Recorded October 22, 2020.

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Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions

Interview with Rishi P. Singh, MD, author of Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data. Hosted by Neil Bressler, MD.

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The costs of the coronavirus pandemic are unprecedented in their dimensions: David M. Cutler, PhD, of Harvard University discusses financial costs: the $16 trillion virus.

Lisa Cooper, MD, MPH, of Johns Hopkins University discusses the costs to communities of color in excess deaths and bereavement.

Charles R. Marmar, MD, of NYU Grossman School of Medicine discusses the mental health costs. Recorded October 20, 2020.

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Andy Slavitt, MBA, discusses recent developments in the COVID-19 pandemic and the US response. Slavitt is former Acting CMS Administrator in the Obama administration, board director at the United States of Care in Washington, DC, and a Distinguished Health Policy Fellow at the Leonard Davis Institute of Health Economics at the University of Pennsylvania in Philadelphia. Recorded October 16, 2020.

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Many people are hoping that enough people develop resistance to COVID-19, either from being exposed to the disease or from vaccination, to develop herd immunity that will enable society to return to normal. But will that happen? Saad Omer, MD, from the Yale Institute for Global Health, discusses his JAMA article on herd immunity and how much we can count on having it to return society to normal from this COVID-19 pandemic.

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The National Academy of Medicine has recommended that racial minority populations receive priority for vaccination because they have been hard hit by the pandemic and are "worse off" socioeconomically. US law is inconsistent on whether race/ethnicity can be an explicit criterion for achieving equity and diversity. Lawrence O. Gostin, JD, of Georgetown University and Michelle A. Williams, ScD, of Harvard T.H. Chan School of Public Health discuss ways to achieve the public health objective of protecting vulnerable communities while adhering to law and ethics. Recorded October 14, 2020.

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Is It Lawful and Ethical to Prioritize Racial Minorities for COVID-19 Vaccines?

University of North Carolina (UNC) at Chapel Hill nutrition scholar Barry Popkin, PhD, and JAMA Medical News Associate Managing Editor Jennifer Abbasi discuss new findings on obesity and COVID-19. Popkin is the lead author of a systematic review and meta-analysis on the topic that was published recently in Obesity Reviews. He is a distinguished professor in the department of nutrition at the UNC Gillings School of Global Public Health.

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Interview with Christopher W. Seymour, MD, MSc, author of Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic

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Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic

On October 2 the US National Academies of Science, Engineering, and Medicine issued its consensus Framework for Equitable Allocation of a COVID-19 Vaccine. William H. Foege, MD, MPH, emeritus distinguished professor of International Health at the Rollins School of Public Health at Emory University, cochaired the committee that authored the report and discusses its recommendations. Recorded October 2, 2020.

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Peter Marks, MD, PhD, directs the US FDA's Center for Biologics Evaluation and Research (CBER) and will "call the balls and strikes" on any COVID-19 vaccine, according to FDA Commissioner Stephen Hahn. He joins JAMA Editor Howard Bauchner, MD, for an update on vaccine progress to date and prospects for pre-election political interference in the FDA approval process. Recorded October 5, 2020.

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Unwavering Regulatory Safeguards for COVID-19 Vaccines

Sarah E. Gollust, PhD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study examining public perception of high priority groups for receipt of an eventual coronavirus disease 2019 vaccine in case of shortage of supply. Read the article here: https://ja.ma/3d2101T.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Sweden’s response to the COVID-19 pandemic differed from its neighbors in Europe. Lockdowns were minimized with the belief that they would be more damaging than the virus itself. Much criticism was levied at the country regarding these policies. Anders Tegnell, MD, is the head of the Department of Public Health Analysis and Data Management, Deputy Director General at the Public Health Agency of Sweden, and had been Sweden's state epidemiologist since 2013. He discusses what Sweden did in response to COVID-19 and what their outcomes were.

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COVID-19 and Health Equity—A New Kind of “Herd Immunity”

The COVID-19 pandemic has disrupted health care in many domains, including mental health services. JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, discuss with Ryan K. McBain, PhD, MPH, of RAND Corporation how the use of mental health care—both in-person and telehealth visits—changed for commercially insured adults during the first year of the COVID-19 pandemic in 2020.

Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the latest developments in the COVID-19 pandemic. Recorded September 25, 2020.

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Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 Vaccine

H. Nina Kim, MD, MSc and Herbert C. Duber, MD, MPH join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study evaluating the proportion of patients tested for coronavirus disease 2019 (COVID-19) and the proportion of positive cases, using language as a surrogate for immigrant status. Read the article here: https://ja.ma/3d2101T.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Michael T. Osterholm, PhD, MPH, returns to JAMA's Coronavirus Q&A series to discuss the latest developments in the COVID-19 pandemic. He is director of the Center for Infectious Disease Research and Policy (CIDRAP) at University of Minnesota and a veteran of pandemic planning. Recorded September 23, 2020.

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Fairly Prioritizing Groups for Access to COVID-19 Vaccines

Hydroxychloroquine and convalescent plasma approvals by the FDA under Emergency Use Authorization (EUA) protocols have raised concerns the agency is under withering political pressure to fast-track a COVID-19 vaccine before it is proven safe and effective. Joshua Sharfstein, MD, Johns Hopkins Bloomberg School of Public Health, and JAMA Associate Editor Preeti Malani, MD, University of Michigan, discuss implications for public health and policy responses to ensure vaccine safety. Recorded September 18, 2020.

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What Happens When COVID-19 Collides With Flu Season?; Flu Vaccination Urged During COVID-19 Pandemic; COVID-19 and mRNA Vaccines—First Large Test for a New Approach

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Science communications expert Dominique Brossard, PhD, and JAMA Medical News Associate Managing Editor Jennifer Abbasi discuss research-based strategies to encourage mask wearing, social distancing, and hand washing during the COVID-19 pandemic. Dr. Brossard is a professor and chair of the Department of Life Sciences Communication at the University of Wisconsin-Madison and part of a new COVID-19-focused National Academies of Science, Engineering, and Medicine group.

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The Science of Persuasion Offers Lessons for COVID-19 Prevention

Interview with Aaron S. Kesselheim, MD, author of Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency

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Song Gao, PhD and Ajay K. Sethi, PhD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study using anonymous location data from 45 million mobile phones to determine if stay-at home orders were associated with decreased median travel distance and slower #COVID19 spread.

Read the article here: https://ja.ma/2ZCqm0A.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

New data show unfavorable US trends in hypertension and obesity, with communities of color doing worse. National Institute of Diabetes and Digestive and Kidney Diseases Director Griffin P. Rodgers, MD, and National Heart, Lung, and Blood Institute Director Gary H. Gibbons, MD, discuss the implications for COVID-19 outcomes and public health. Recorded September 10, 2020.

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Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018

David O. Meltzer, MD, PhD, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study examining whether patients’ most recent vitamin D levels and treatment for insufficient vitamin D levels are associated with test results for coronavirus disease 2019 (COVID-19).

Read the article here: https://ja.ma/2ZkvGpf.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Matthew S. Durstenfeld, MD, MAS, and Priscilla Y. Hsue, MD, authors of Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults: A Systematic Review and Meta-analysis. Hosted by Angel N. Desai, MD, MPH.

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JAMA Pediatrics Editors' Summary by Dimitri Christakis, MD, MPH, Editor in Chief, and Frederick Rivara, MD, MPH, Editor in Chief of JAMA Network Open for the September 8, 2020 issue.

A conversation with Jonathan A. C. Sterne, MA, MSc, PhD, of the University of Bristol, Todd W. Rice, MD, MSc, of Vanderbilt University, and Janet V. Diaz, MD, of the World Health Organization (WHO) on the latest research supporting the use of hydrocortisone and dexamethasone for treatment of COVID-19 ARDS. Recorded September 2, 2020.

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COVID-19 continues to rapidly spread throughout the world. In the past few months, the population affected by the disease has shifted from older to younger patients. Public health officials are concerned that younger people seem not to be very compliant with recommendations regarding masking and social distancing. It is believed that younger people think that the adverse consequences of the disease occur in the elderly and not in them. Garret Salzman, MD, is a resident physician at UCLA and contracted the disease. He is young and healthy, but he has had substantial disability from COVID-19. He tells a cautionary tale of his experience with COVID-19 that this is not a benign disease in young people, that they need to be careful.

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Paul A. Offit, MD, of the Children's Hospital of Philadelphia provides an update on COVID-19 vaccine development. Recorded August 24, 2020.

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Alyssa Bilinski, MS, and Joshua A. Salomon, PhD, join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a mathematical modeling study examining the potential for contract tracing to reduce the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the context of reduced physical distancing under different assumptions for case detection, tracing, and quarantine efficacy. Read the article here: https://ja.ma/3ixDJ9j

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open.

Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

CDC Director Robert Redfield, MD, discusses recent developments in the COVID-19 pandemic and US response, including prospects for dual outbreaks of COVID-19 and influenza in the fall and winter.

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Addressing Influenza Vaccination Disparities During the COVID-19 Pandemic

Ezekiel Emanuel, MD, PhD, of the University of Pennsylvania's Perelman School of Medicine, Department of Medical Ethics and Health Policy, discusses recent developments in the COVID-19 pandemic. Recorded August 19, 2020.

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Before COVID-19, even though most children got vaccinated for measles, too many did not, resulting in worsening outbreaks of measles. People forgot how bad a disease measles is and became lax about getting their children vaccinated. Now in the COVID-19 era everyone is aware of what an out-of-control infectious disease can do and we are all anxiously awaiting a COVID-19 vaccine. Will this experience help encourage parents to get their children vaccinated? We discussed the problems of an adequate measles vaccination with Dr. Saad Omer, PhD, from the Yale Institute for Global Health at Yale University in New Haven, Connecticut.

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Vaccine Refusal and Measles Outbreaks in the US

As the COVID-19 pandemic continues to spread throughout the world, flu season is almost upon us. This is concerning because there will be an overlap between flu and COVID-19 and patients could get both diseases. Daniel Solomon, MD, from the Division of Infectious Diseases at the Brigham and Women’s Hospital of the Harvard Medical School in Boston, discusses COVID-19 and how the flu might pan out this year.

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One of the most contentious issues relating to COVID-19 is when to reopen schools. This is a complicated matter because placing people in close quarters risks spread of the disease. Yet children being at home makes it difficult for their working parents to manage their affairs and can potentially affect the learning experience. JAMA Associate Editor Preeti Malani, MD, chief health officer for the University of Michigan, discusses school reopening and how the University of Michigan is addressing this problem.

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In July 2022, Nahid Bhadelia, MD, MALD, joined the White House COVID-19 Response Team as senior policy advisor for Global COVID Response. The infectious disease physician, who is on sabbatical from Boston University, spoke with JAMA Associate Managing News Editor Jennifer Abbasi about the pandemic’s true burden of disease in low- and middle-income countries and ongoing COVID-19 vaccine inequity.

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The use of hydroxychloroquine as a treatment for COVID-19 serves as an example of what is wrong with medical information being widely disseminated before it is thoroughly vetted by peer review. Preliminary studies of this treatment modality were spread widely, creating false hope that a treatment for COVID-19 existed. Several randomized trials have shown that hydroxychloroquine is not an effective therapy for COVID-19.

David Juurlink, MD, PhD, from the University of Toronto summarizes the evidence base regarding hydroxychloroquine and COVID-19.

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Harvey W. Kaufman, MD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study examining changes in the number of patients with newly identified cancer before and during the coronavirus disease 2019 (COVID-19) pandemic in the United States.

Read the article here: https://ja.ma/31khw7X.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Soumya Swaminathan, MD, DNB, chief scientist at the World Health Organization (WHO), discusses the global coronavirus pandemic and the WHO response. Recorded August 5, 2020.

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