Explorez tous les épisodes du podcast CME in Minutes: Education in Oncology & Hematology

Please visit answersincme.com/860/IME-26-0163-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Véronique Diéras, MD; Peter A. Fasching, MD; and Sara A. Hurvitz, MD, FACP. In this activity, experts in breast cancer discuss evidence and implementation of first-line treatment options, including novel regimens, for HER2-positive metastatic disease. Upon completion of this activity, participants should be better able to: Specify first-line treatment recommendations for patients with HER2-positive unresectable or metastatic breast cancer (mBC); Assess the evidence for novel recommended first-line therapy regimens for HER2-positive mBC; Determine which patients with HER2-positive mBC are candidates for various recommended first-line therapies according to patient, treatment, and disease factors; and Formulate strategies to optimally manage care for patients on novel first-line treatment regimens for HER2-positive mBC.

Please visit answersincme.com/860/MED-ONC-03731-replay1 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Sunandana Chandra, MD, MS; Vishal A. Patel, MD; Vernon K. Sondak, MD; and Jessica Kalen, MD, FAAD. In this activity, experts in skin cancer discuss the current use of immunotherapy-based treatment approaches in resectable cutaneous squamous cell carcinoma (CSCC), with a focus on the role of dermatologists in the multidisciplinary team. Upon completion of this activity, participants should be better able to: Outline guideline-recommended clinical approaches for the management of patients with early-stage CSCC; Specify key real-world considerations that influence the appropriate use of neoadjuvant and adjuvant immunotherapy in resectable CSCC, within the context of multidisciplinary care; and Formulate a collaborative care plan that defines the roles and responsibilities of multidisciplinary team members to optimize outcomes for patients with resectable CSCC who are candidates for neoadjuvant and/or adjuvant immunotherapy. This activity is intended for US healthcare professionals only.

Please visit answersincme.com/860/104092969-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Beth Faiman, PhD, MSN, APN-BC, TCTCN, AOCN, FAAN, FAPO; and Jesus Berdeja, MD. In this activity, experts in hematology-oncology discuss the evolving role of cereblon E3 ligase modulators (CELMoDs) in patients with relapsed/refractory multiple myeloma (RRMM). Upon completion of this activity, participants should be better able to: Identify the role of CELMoDs in the treatment of patients with RRMM. Utilize evidence-based practical strategies for the management of key adverse events associated with CELMoDs in patients with RRMM. Apply key considerations to support the integration of CELMoDs into the treatment paradigm for patients with RRMM.

Please visit answersincme.com/860/2026-MC-002375-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Beth Faiman, PhD, MSN, APN-BC, TCTCN, AOCN, FAAN, FAPO; and Krina Patel, MD, MSc. In this activity, experts in multiple myeloma discuss key treatment considerations and personalization strategies for anti-CD38 therapy. Upon completion of this activity, participants should be better able to: Evaluate the clinical implications of key data supporting anti-CD38–based regimens in patients with multiple myeloma (MM); Outline evidence-based strategies to manage toxicities associated with anti-CD38–based therapies; Identify key considerations for integrating anti-CD38 monoclonal antibodies into treatment plans for patients with MM; and Apply practical, patient-centered care considerations to optimize outcomes with anti-CD38 monoclonal antibodies for patients with MM.

Please visit answersincme.com/CJF860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Manuel Rodriguez-Justo, MBBCh, MSc, MD, FRCPath; and Elizabeth Smyth, MD, FRCP. In this activity, experts in oncology and pathology discuss the impact of claudin 18.2 (CLDN18.2) tests and treatments for patients with advanced gastric or gastroesophageal junction cancers. Upon completion of this activity, participants should be better able to: Describe the rationale for CLDN18.2 testing in patients with advanced gastric and gastroesophageal junction cancers (GC/GEJC); Review the potential clinical impact of emerging CLDN18.2-targeted antibody-drug conjugates (ADCs) for the treatment of GC/GEJC; and Outline evidence-based, emerging strategies to optimize outcomes in patients with advanced GC/GEJC.

Please visit answersincme.com/MSM860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Ritu Salani, MD; and Courtney Arn, CNP. In this activity, experts in gynecological oncology discuss antibody-drug conjugates (ADCs) in ovarian, cervical, and endometrial cancers. Upon completion of this activity, participants should be better able to: Describe the rationale for using ADCs in previously treated patients with gynecologic cancers; Assess the safety and tolerability evidence for approved ADC therapies in gynecologic cancers; Formulate management strategies for adverse events associated with ADC treatment of ovarian, cervical, and endometrial cancers; and Outline patient-centered approaches to facilitate adherence with ADC therapy.

Please visit answersincme.com/WAY860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Elizabeth O'Donnell, MD. In this activity, an expert in multi-cancer early detection (MCED) discusses strategies to apply MCED testing into everyday clinical practice. Upon completion of this activity, participants should be better able to: Discuss the benefits and risks of MCED testing; and Outline patient-centered strategies to appropriately incorporate MCED testing into the primary care setting.

Please visit answersincme.com/860/cvdprostate-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Michael Cookson, MD; Alicia Morgans, MD, MPH; and Avirup Guha, MD, MBBS, MPH, FAHA, FACC, FESC, FICOS. In this activity, experts in prostate cancer discuss cardiovascular risk in patients receiving androgen-deprivation therapy (ADT). Upon completion of this activity, participants should be better able to: Evaluate the impacts of prostate cancer and ADT on cardiovascular risk; Translate the latest research for cardiovascular management of patients on ADT to clinical practice; and Design personalized treatment approaches to optimize ADT across treatment settings.

Please visit answersincme.com/NHB860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Zev Wainberg, MD. In this activity, an expert in oncology discusses the use of TROP2-directed antibody-drug conjugates (ADCs) across solid tumors. Upon completion of this activity, participants should be better able to: Review the rationale for targeting TROP2 with antibody-drug conjugates (ADCs) across tumor stages and settings; Evaluate the clinical profiles of available and emerging TROP-targeting ADCs across tumor stages and settings; and Apply evidence-based strategies to recognize and monitor treatment-related adverse events (TRAEs) associated with ADCs.

Please visit answersincme.com/KNY860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Barbara Melosky, MD, FRCPC; and Alyson Chin, RN, BScN, MN-ACNP(A). In this activity, experts in lung cancer discuss the management of adverse events associated with tyrosine kinase inhibitor use in patients with ALK-positive metastatic non–small-cell lung cancer. Upon completion of this activity, participants should be better able to: Identify ALK tyrosine kinase inhibitor (TKI)–related adverse events (AEs) among patients with ALK-positive (ALK+) metastatic non–small-cell lung cancer (mNSCLC); Apply strategies to effectively monitor and manage ALK TKI–related AEs to enhance treatment adherence in patients with ALK+ mNSCLC; and Outline multidisciplinary, patient-centered strategies to optimize care for patients receiving ALK TKIs for ALK+ mNSCLC.

Please visit answersincme.com/RVH860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Vivien Brown, MDCM, CCFP, FCFP, MSCP. In this activity, an expert in menopause management in primary care discusses identification and treatment of menopause-related vasomotor symptoms (VMS). Upon completion of this activity, participants should be better able to: Integrate communication about menopause and VMS into routine patient encounters; Review treatment options for moderate to severe VMS, including NK receptor antagonists, with patients using a shared decision-making approach; and Formulate strategies for optimally monitoring patients who are receiving NK receptor antagonists for menopause-related VMS.

Please visit answersincme.com/JKK860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Alison J. Birtle, FRCP, FRCR, MD; and Niklas Klümper, MD. In this activity, experts in oncology discuss systemic therapies for locally advanced and metastatic urothelial carcinoma. Upon completion of this activity, participants should be better able to: Assess the evidence for recommended systemic treatment regimens for patients with LA/mUC in the context of treatment guidelines; Propose appropriate patient assessment strategies to guide systemic therapy decisions; and Formulate individualized treatment strategies to optimize outcomes for patients with LA/mUC using recommended first-line systemic treatments.

Please visit answersincme.com/NDX860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Tycel J. Phillips, MD and Steven Horwitz, MD. In this activity, experts in B-cell and T-cell lymphomas discuss EZH inhibitors for non-Hodgkin lymphoma. Upon completion of this activity, participants should be better able to: Discuss the rationale for EZH inhibitors in relapsed/refractory (R/R) non-Hodgkin lymphoma (NHL); Describe the clinical profiles of available and emerging EZH inhibitors; and Outline current and potential methods of optimizing EZH inhibitors in clinical practice based on available evidence.

Please visit answersincme.com/ZGK860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Amer Zeidan, MBBS, MHS. In this activity, an expert in myelodysplastic syndromes (MDS) discusses approaches to optimize management of anemia in lower-risk MDS. Upon completion of this activity, participants should be better able to: Translate the latest clinical trial data to the management of patients with lower-risk MDS; Evaluate evidence-based strategies for optimizing the use of available agents in lower-risk MDS; and Design treatment plans that effectively sequence available therapies in patients with lower-risk MDS.

Please visit answersincme.com/XUG860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Sara A. Hurvitz, MD, FACP. In this activity, an expert in breast cancer discusses the evidence for TROP2-directed antibody-drug conjugates in metastatic triple-negative disease (mTNBC). Upon completion of this activity, participants should be better able to: Review the clinical impact of TROP2-directed antibody-drug conjugates (ADCs) for the management of mTNBC; Evaluate the clinical implications of the evidence exploring first-line use of TROP2 ADCs in combination with immunotherapy for mTNBC; and Develop an evidence-informed strategy that incorporates TROP2-directed ADCs and immunotherapy combinations into first-line management of mTNBC, where appropriate.

Please visit answersincme.com/GFY860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Vishal A. Patel, MD; and Jonathan S. Zager, MD, FACS, FSSO. In this activity, experts in cutaneous oncology discuss the evolving role of gene expression profiling (GEP) tests in refining risk assessment and supporting individualized, multidisciplinary management strategies for patients with melanoma. Upon completion of this activity, participants should be better able to: Identify the clinical rationale for using GEP tests to stratify the risk of disease progression in patients with cutaneous melanoma; Review the clinical evidence, including guideline-supported data, for GEP tests to stratify disease progression risk in patients with cutaneous melanoma; Formulate multidisciplinary strategies for incorporating the results of GEP tests into risk-based management of patients with cutaneous melanoma; and Outline patient-centered approaches to integrating GEP tests into the management of patients with cutaneous melanoma at risk of metastasis.

Please visit answersincme.com/860/103117485-replay3 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Prof. Solange Peters, MD, PhD and David Harpole, MD. In this activity, experts in EGFR-mutated advanced non–small-cell lung cancer (NSCLC) discuss current and emerging strategies for sequencing therapies beyond progression. Upon completion of this activity, participants should be better able to: Evaluate sequencing strategies for patients with advanced EGFR-mutated NSCLC following first-line progression, applying biologic insights and genomic testing to guide optimal therapy selection; and Discuss the role of emerging therapies in advanced EGFR-mutated NSCLC, applying insights from tumor biology to optimize sequential treatment decisions.

Please visit answersincme.com/860/2026-MC-002106-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by María-Victoria Mateos, MD, PhD; and Joseph Mikhael, MD, MEd, FRCPC, FACP, FASCO. In this activity, experts in multiple myeloma discuss evidence-based strategies to personalize frontline care with anti-CD38-based quadruplets in patients with newly diagnosed myeloma. Upon completion of this activity, participants should be better able to: Identify key clinical factors that inform tailored frontline treatment approaches in patients with NDMM; Evaluate the clinical implications of key data supporting evolving frontline treatment approaches with anti-CD38–based quadruplet regimens in patients with NDMM; and Outline evidence-based strategies to integrate emerging treatment approaches into the clinical workflow of patient care in NDMM.

Please visit answersincme.com/860/103117485-replay2 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Prof. Solange Peters, MD, PhD; and Benjamin Levy, MD, FASCO. In this activity, experts in EGFR-mutated advanced non–small-cell lung cancer (NSCLC) discuss how tumor biology and genomic reassessment can guide sequencing after first-line progression. Upon completion of this activity, participants should be better able to: Evaluate sequencing strategies for patients with advanced EGFR-mutated NSCLC following first-line progression, applying biologic insights and genomic testing to guide optimal therapy selection; and Discuss the role of emerging therapies in advanced EGFR-mutated NSCLC, applying insights from tumor biology to optimize sequential treatment decisions.

Please visit answersincme.com/860/101707775-replay2 to participate, download slides and supporting materials, complete the post test, and get a certificate. [Presented by Erika Hamilton, MD, FASCO; Komal Jhaveri, MD, FACP, FASCO; and John Allen Piede, MD. In this activity, experts in breast cancer provide a practical, community-focused discussion on integrating ESR1 mutation testing, applying emerging data on novel endocrine therapies, such as SERDs, and personalizing treatment strategies for patients with HR+, HER2− advanced breast cancer. Upon completion of this activity, participants should be better able to: Integrate testing for ESR1 mutations at appropriate times into practice workflows in the treatment of patients with HR-positive, HER2-negative advanced breast cancer; Evaluate the clinical implications of the latest evidence for approved and late-stage emerging novel oral SERDs in patients with HR-positive, HER2-negative advanced breast cancer; and Apply multidisciplinary, patient-centered strategies for optimizing treatment outcomes with novel oral SERDs in patients with HR-positive, HER2-negative advanced breast cancer.

Please visit answersincme.com/860/101707775-replay1 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Erika Hamilton, MD, FASCO; Komal Jhaveri, MD, FACP, FASCO; and Eleonora Teplinsky, MD, FASCO. In this activity, experts in breast cancer provide a practical, community-focused discussion on integrating ESR1 mutation testing, applying emerging data on novel endocrine therapies, such as SERDs, and personalizing treatment strategies for patients with HR+, HER2− advanced breast cancer. Upon completion of this activity, participants should be better able to: Integrate testing for ESR1 mutations at appropriate times into practice workflows in the treatment of patients with HR-positive, HER2-negative advanced breast cancer; Evaluate the clinical implications of the latest evidence for approved and late-stage emerging novel oral SERDs in patients with HR-positive, HER2-negative advanced breast cancer; and Apply multidisciplinary, patient-centered strategies for optimizing treatment outcomes with novel oral SERDs in patients with HR-positive, HER2-negative advanced breast cancer.

Please visit answersincme.com/BXW860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Katarzyna J. Jerzak, MD, MSc, FRCPC. In this activity, an expert in medical oncology reviews the optimal use of CDK4/6 inhibitors for the treatment of hormone receptor (HR)–positive/HER2-negative early and metastatic breast cancer based on the latest guidelines and long-term evidence. Upon completion of this activity, participants should be better able to: Define patient eligibility for CDK4/6 inhibitor therapy in hormone receptor (HR)–positive/HER2-negative early and metastatic breast cancer per the Research Excellence, Active Leadership (REAL) Canadian Breast Cancer Alliance recommendations; Evaluate long-term clinical evidence supporting CDK4/6 inhibitors with endocrine therapy in HR-positive/HER2-negative early and metastatic breast cancer; and Apply evidence-based, patient-centered strategies to optimize long-term management of HR-positive/HER2-negative early and metastatic breast cancer.

Please visit answersincme.com/860/103518989-replay3 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by John Strickler, MD and Chiara Cremolini, MD, PhD. In this activity, experts in metastatic colorectal cancer (mCRC) discuss real-world evidence and clinical insights related to durable responses and long-term benefits in later-line care. Upon completion of this activity, participants should be better able to: Propose treatment plans based on predictors of durable benefit and real-world evidence.

Please visit answersincme.com/860/MED-ONC-03814-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Neil D. Gross, MD, FACS; Nikhil I. Khushalani, MD; and Emily S. Ruiz, MD, MPH. In this activity, leading skin cancer experts guide an interactive, multidisciplinary case-based discussion on optimizing (neo)adjuvant immunotherapy for high-risk, resectable cutaneous squamous cell carcinoma (CSCC). Upon completion of this activity, participants should be better able to: Apply the latest clinical trial data and guideline recommendations to treatment planning for patients with high-risk, resectable CSCC; Recognize when to incorporate systemic neoadjuvant and adjuvant immunotherapy in patients with CSCC based on clinical and pathological features; and Propose strategies to optimize care for patients with high-risk CSCC through the evidence-based use of neoadjuvant and adjuvant immunotherapy within multidisciplinary care plans.

Please visit answersincme.com/860/102331945-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Elizabeth Smyth, MD, FRCP and Daniela Molena, MD. In this activity, experts in gastric/gastroesophageal junction adenocarcinoma discuss the latest evidence and practical strategies for optimizing the treatment of resectable gastric (G)/gastroesophageal junction (GEJ) adenocarcinoma with perioperative immunotherapy. Upon completion of this activity, participants should be better able to: Evaluate the evidence supporting the integration of perioperative immunotherapy (IO) in the treatment of resectable gastric (G)/gastroesophageal junction (GEJ) adenocarcinoma; Analyze the role of biomarkers in decision-making for perioperative IO in resectable G/GEJ adenocarcinoma; and Outline multidisciplinary strategies for optimizing the care of patients receiving perioperative IO for resectable G/GEJ adenocarcinoma.

Please visit answersincme.com/860/103117485-replay1 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Prof. Solange Peters, MD, PhD; and Pasi A. Jänne, MD, PhD. In this activity, experts in EGFR-mutated advanced non–small-cell lung cancer (NSCLC) discuss practical strategies for optimizing first-line testing and treatment selection. Upon completion of this series, participants should be better able to: Interpret updated evidence and recommendations regarding first-line testing and treatment selection for patients with advanced EGFR-mutated NSCLC; and Discuss the role of emerging therapies in advanced EGFR-mutated NSCLC, applying insights from tumor biology to optimize sequential treatment decisions.

Please visit answersincme.com/860/101834101-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Simpa S. Salami, MD, MPH; and Neal D. Shore, MD, FACS. In this activity, experts in prostate cancer discuss new evidence for individualized, evidence-based treatment strategies in metastatic hormone-sensitive disease. Upon completion of this activity, participants should be better able to: Evaluate the clinical implications of the most recent data informing the standard of care treatment options for mHSPC; Integrate patient-, disease-, and therapy-related factors to develop individualized, evidence-based treatment strategies for mHSPC; and Design patient-centered care approaches that balance the benefit and risk of treatment to optimize outcomes in mHSPC.

Please visit answersincme.com/TNM860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Richard Kim, MD. In this activity, an expert in oncology discusses when and how to sequence later-line and chemotherapy-free therapies in metastatic colorectal cancer (mCRC). Upon completion of this activity, participants should be better able to: Evaluate factors influencing a treatment switch from cytotoxic agents for patients with stable metastatic colorectal cancer (mCRC); Formulate practical approaches for transitioning from chemotherapy to tyrosine kinase inhibitor (TKI) treatment in later-line settings for patients with mCRC; and Describe strategies to prolong chemotherapy-free disease control with TKIs.

Please visit answersincme.com/KJW860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Aman Chauhan, MD and Rhonda K. Yantiss, MD. In this activity, experts in medical oncology and pathology discuss identification and treatment of extrapulmonary neuroendocrine carcinomas and extrapulmonary neuroendocrine tumors. Upon completion of this activity, participants should be better able to: Differentiate extrapulmonary neuroendocrine carcinoma (EP-NEC) from extrapulmonary neuroendocrine tumors (EP-NETs); Identify diagnostic and pathological approaches to improve the recognition and accurate classification of EP-NEC and EP-NET; Evaluate emerging clinical data on DLL3-targeting bispecific TCE agents in the treatment of EP-NEC and EP-NET; and Formulate evidence-based strategies to integrate DLL3-targeting bispecific TCE therapies into evolving treatment paradigms for EP-NEC and EP-NET.

Please visit answersincme.com/DDT860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Robert Haddad, MD. In this activity, an expert in medical oncology discusses locally advanced head and neck squamous cell carcinoma (LA HNSCC). Upon completion of this activity, participants should be better able to: Discuss the clinical implications of the latest data for approved and recommended regimens for resectable LA HNSCC in the pre- and postoperative settings; Outline strategies to integrate immunotherapy into pre- and postoperative settings for resectable LA HNSCC, in the context of conventional treatment; and Apply multidisciplinary team approaches to effectively manage patients with LA HNSCC across pre- and postoperative treatment phases.

Please visit answersincme.com/860/103518989-replay2 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by John Strickler, MD and Tanios Bekaii-Saab, MD. In this activity, experts in metastatic colorectal cancer (mCRC) discuss proactive toxicity management and dose optimization strategies to help patients remain on treatment and improve outcomes. Upon completion of this activity, participants should be better able to: Integrate proactive management strategies to maintain patients on later-line therapy.

Please visit answersincme.com/860/103518989-replay1 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by John Strickler, MD; and Daniel Ahn, DO, MS. In this activity, experts in metastatic colorectal cancer (mCRC) discuss strategies for sequencing later-line therapies and planning treatment pathways to preserve future options. Upon completion of this series, participants should be better able to: Apply evidence-based strategies for later-line treatment selection in mCRC; Integrate proactive management strategies to maintain patients on later-line therapy; and Propose treatment plans based on predictors of durable benefit and real-world evidence.

Please visit answersincme.com/860/102724337-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Charu Aggarwal, MD, MPH, FASCO; and Benjamin Levy, MD, FASCO. In this activity, expert oncologists will engage in a case-based discussion examining how current guidelines and evidence inform the use of frontline immunotherapy-based regimens in the management of metastatic non–small-cell lung cancer (NSCLC). Upon completion of this activity, participants should be better able to: Review the latest evidence for IO-based regimens in first-line metastatic NSCLC; Apply evidence-based approaches to select IO-based regimens for first-line metastatic NSCLC, based on patient types; Propose workflows that ensure timely biomarker testing and minimize delays in initiating optimal IO-based therapy; and Outline strategies to manage common and serious AEs associated with preferred first-line IO-based regimens, without losing disease control.

Please visit answersincme.com/UZA860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Anne Lynn S. Chang, MD and Zeynep Eroglu, MD. In this activity, experts in nonmelanoma skin cancer discuss clinical advances for the use of immunotherapy for the management of basal cell carcinoma (BCC). Upon completion of this activity, participants should be better able to: Evaluate current guideline-based recommendations for the use of immunotherapy in the management of basal cell carcinoma (BCC) across various stages of disease; Apply evidence-driven criteria to identify patients with BCC who may be appropriate candidates for immunotherapeutic intervention; and Determine real-world clinical approaches to optimize the benefit-risk profiles of immunotherapy in the management of BC.

Please visit answersincme.com/GXT860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Sarah Donahue, MPH, ANP, AOCNP. In this activity an expert in breast cancer discusses the efficacy and safety of oral SERDs in HR+, HER2- advanced breast cancer. Upon completion of this activity, participants should be better able to: Review the evidence-based use of oral SERDs in the treatment plan for patients with HR+, HER2- advanced breast cancer; Specify the key roles of nurses and NPs in optimizing the overall care for patients with HR+, HER2- advanced breast cancer who are candidates for oral SERDs; and Outline a multidisciplinary treatment plan to maximize the long-term care of patients with HR+, HER2- advanced breast cancer.

Please visit answersincme.com/860/102769007-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Aiwu Ruth He, MD, PhD and Mehmet Akce, MD. In this activity, experts in hepatocellular carcinoma (HCC) discuss how the current and emerging clinical evidence for immune checkpoint inhibitor (ICI)–based regimens can elevate personalized care across disease stages, now and into the future. Upon completion of this activity, participants should be better able to: Evaluate the clinical evidence supporting immune checkpoint inhibitor (ICI)–based regimens for the treatment of hepatocellular carcinoma (HCC) across disease settings; Differentiate available ICI-based combination regimens to inform appropriate frontline treatment selection for patients with unresectable HCC; Apply evidence-based strategies to manage immune-related and regimen-specific toxicities associated with ICI-based regimens in patients with HCC; and Design long-term, personalized treatment plans that integrate patient- and disease-related factors into decision-making for HCC.

Please visit answersincme.com/860/IME_2025_00012595-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by John V. Heymach, MD, PhD; and Mark Awad, MD, PhD. In this activity, experts in oncology discuss the role of dual and HER2-selective oral tyrosine kinase inhibitors in patients with HER2-mutated non–small-cell lung cancer. Upon completion of this activity, participants should be better able to: Specify how TKIs may address unmet therapeutic needs for diverse patient populations with HER2-mutated NSCLC; Interpret the clinical evidence for approved oral TKIs for patients with HER2-mutated NSCLC; and Assess which patients may be candidates for approved oral HER2-targeting TKIs in the context of the current standard of care.

Please visit answersincme.com/860/2026-MC-001665-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Ajai Chari, MD; Caitlin Costello, MD; and Beth Faiman, PhD, MSN, APN-BC, TCTCN, AOCN, FAAN, FAPO. In this activity, experts in multiple myeloma (MM) discuss the therapeutic rationale, clinical data, and practical integration of subcutaneous anti-CD38 therapies to optimize care for patients with MM. Upon completion of this activity, participants should be better able to: Recognize the rationale for using subcutaneous (SC) formulations of anti-CD38 monoclonal antibodies in patients with multiple myeloma (MM); Assess the clinical profiles of approved and emerging SC formulations of anti-CD38 monoclonal antibodies in patients with MM; and Outline evidence-based, patient-centered strategies for optimizing outcomes with SC formulations of anti-CD38 monoclonal antibodies in patients with MM.

Please visit answersincme.com/860/101385133-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Peter A. Fasching, MD; Michael Gnant, MD, FACS; and Cristina Saura Manich, MD, PhD. In this activity, experts in breast cancer discuss new evidence in neoadjuvant and adjuvant care of early disease. Upon completion of this activity, participants should be better able to: Describe multidisciplinary viewpoints on the role that HER2-directed ADCs may play in the (neo)adjuvant setting for HER2-positive early-stage breast cancer; Evaluate evidence for the (neo)adjuvant use of HER2-directed ADCs in the multidisciplinary management of HER2-positive early-stage breast cancer; and Formulate evidence-based multidisciplinary strategies to optimally incorporate (neo)adjuvant HER2-directed ADCs into the treatment paradigm for HER2-positive early-stage breast cancer.

Please visit answersincme.com/PNQ860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Rachel Goodwin, MSc, MD, FRCPC; and Vincent Tam, MD. In this activity, experts in colorectal cancer and biliary tract cancer discuss first-line immunotherapy considerations. Upon completion of this activity, participants should be better able to: Evaluate the clinical profiles of first-line immunotherapy-based regimens for the treatment of patients with advanced colorectal cancer (CRC); Formulate strategies to individualize first-line immunotherapy-based regimens for patients with advanced CRC; Describe the clinical evidence on first-line immunotherapy-based regimens for patients with advanced biliary tract cancer (BTC); and Apply patient-, drug-, and disease-specific considerations to optimize first-line immunotherapy-based regimens for patients with advanced BTC.

Please visit answersincme.com/CKX860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Prithviraj Bose, MD. In this activity, an expert in hematology discusses the role of current and emerging treatment options for patients living with advanced systemic mastocytosis. Upon completion of this activity, participants should be better able to: Identify prognostic features of advanced systemic mastocytosis (AdvSM) that guide diagnosis and care planning; Describe current and emerging treatment options for patients with AdvSM; and Evaluate patient- and disease-related strategies that inform treatment selection in AdvSM.

Please visit answersincme.com/GYB860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Pasi A. Jänne, MD, PhD, FASCO. In this activity, an expert in oncology discusses the role of emerging KRAS inhibitors in the treatment paradigm for non–small-cell lung cancer (NSCLC). Upon completion of this activity, participants should be better able to: Explain the rationale for targeted therapy in previously untreated patients with KRAS-mutant NSCLC in the context of current standard of care with chemoimmunotherapy; Interpret the clinical evidence for emerging KRAS inhibitors in patients with previously untreated NSCLC; and Propose how emerging KRAS inhibitors may fit into the treatment paradigm for treatment-naive patients with KRAS-mutant NSCLC.

Please visit answersincme.com/NZU860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Sebastien J. Hotte, MD, FRCPC. In this activity, an expert in oncology discusses radioligand therapy for metastatic castration-resistant prostate cancer. Upon completion of this activity, participants should be better able to: Evaluate how the current guidelines and evidence may inform the sequencing of radioligand therapies in patients with metastatic castration-resistant prostate cancer (mCRPC); Apply evidence-based approaches to optimally sequence radioligand therapies in patients with mCRPC; and Identify strategies to optimize bone health management in patients with mCRPC.

Please visit answersincme.com/860/102771731-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Sairah Ahmed, MD; and Sharon Marie Castellino, MD, MSc. In this activity, experts in Hodgkin lymphoma discuss unmet needs and emerging data in the treatment of classical HL. Upon completion of this activity, participants should be better able to: Explain the rationale for investigating ICI-based regimens for previously untreated advanced cHL; Interpret the emerging clinical evidence for ICI-based regimens in patients with previously untreated advanced cHL; and Propose how emerging ICI-based regimens, as they become available, may fit into the treatment paradigm for adult and pediatric patients with previously untreated advanced cHL.

Please visit answersincme.com/ZTY860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Daniel J. DeAngelo, MD, PhD. In this activity, an expert in hematology discusses targeted treatment options for the management of indolent systemic mastocytosis. Upon completion of this activity, participants should be better able to: Recognize the impacts of indolent systemic mastocytosis (ISM) on patients’ quality of life; Discuss the clinical significance of selective KIT D816V–targeting tyrosine kinase inhibitors (TKIs) in the management of patients with ISM; and Design patient-centered strategies for integrating selective KIT D816V–targeting TKIs into the management of ISM.

Please visit answersincme.com/NYR860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Jill Liss, MD, MSCP; Denise Black, MD, FRCSC; and Danielle Covarrubias. In this activity, experts in women’s health, joined by a patient advocate, discuss the burden of menopause-related vasomotor symptoms (VMS) and novel management strategies. Upon completion of this activity, participants should be better able to: Identify the impact and burden of VMS as a consequence of menopause; Outline the clinical rationale for novel therapeutic approaches to manage menopause-related VMS; Evaluate the efficacy and safety of novel neurokinin-targeted therapies for treating menopause-related VMS; and Implement patient-centered clinical approaches to improve outcomes for patients experiencing menopause-related VMS.

Please visit answersincme.com/860/102653681-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Jesus Berdeja, MD; and Saad Z. Usmani, MD, MBA, FACP, FASCO. In this activity, experts in multiple myeloma (MM) discuss how BCMA bispecific antibody (BsAb)–anti-CD38 monoclonal antibody combinations fit into the treatment paradigm for patients with relapsed/refractory MM. Upon completion of this activity, participants should be better able to: Recognize the clinical rationale for using BCMA BsAbs in combination with anti-CD38 antibodies in the treatment of patients with RRMM; Review the clinical implications of the latest efficacy and safety data for BCMA BsAbs in combination with anti-CD38 antibodies in patients with RRMM; Outline potential considerations for integrating BCMA BsAbs in combination with anti-CD38 antibodies, as they become available, into the treatment of patients with RRMM, in the community setting; and Apply practical tools for optimizing the use of BCMA BsAbs in the community setting.

Please visit answersincme.com/AXB860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Bijal Shah, MD, MS. In this activity, an expert in oncology discusses B-cell acute lymphoblastic leukemia. Upon completion of this activity, participants should be better able to: Describe the rationale for the development of novel dual CD19 x CD3-targeting bispecific antibodies for patients with relapsed/refractory; B-cell acute lymphoblastic leukemia (R/R B-ALL); Discuss the safety profiles of available and emerging CD19 x CD3-targeting bispecific antibodies; and Design treatment plans for patients with R/R B-ALL that optimize the current and future use of CD19 x CD3-targeting bispecific antibodies.

Please visit answersincme.com/860/240201307-replay3 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Aly-Khan A. Lalani, MD, FRCPC; Normand Blais, MD, MSc; and Dorothy Lo, MD, FRCP(C), MHSc, PhD. In this activity, experts in managing urothelial carcinoma and renal cell carcinoma (RCC) from across Canada discuss evidence-based strategies for integrating the latest systemic therapies into practice to optimize outcomes for patients with advanced urothelial carcinoma and resected/advanced RCC, with insights into regional practice considerations. Upon completion of this activity, participants should be better able to: Incorporate the latest evidence on frontline combination regimens into treatment planning for advanced urothelial carcinoma; Identify strategies to optimally incorporate adjuvant immunotherapy into treatment plans for eligible patients with early-stage renal cell carcinoma (RCC); and Evaluate how current evidence and guidelines may inform optimal sequencing of therapies in later-line settings for patients with advanced RCC.

Please visit answersincme.com/860/240201373-replay to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Julie Stakiw, MD, FRCPC; and Constantine S. Tam, MBBS, MD. In this activity, experts in chronic lymphocytic leukemia (CLL) use case examples to discuss treatment management of high-risk CLL in both the frontline and relapsed/refractory settings. Upon completion of this activity, participants should be better able to: Identify high-risk chronic lymphocytic leukemia (CLL) based on cytogenetic, genomic, and clinical risk factors; Evaluate the latest clinical evidence informing the use of treatments for high-risk CLL in the frontline and relapsed/refractory (R/R) settings; and Apply guideline-concordant, evidence-based strategies to appropriately select and sequence treatments for high-risk CLL in the frontline and R/R settings.