From the ground floor to the C-Suite, Building Biotechs offers a behind-the-scenes look into the strategy that goes into launching and scaling successful biotech and life science companies.
We talk with biotech executives, founders, HR leaders, and culture builders to learn how they think about growing companies with intention, and discuss the valuable lessons they’ve learned along the way.
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How to Build a Lean, Mean Biotech Machine: with Bogdan Knezevic, founder of Kaleidoscope Bio
Épisode 46
mardi 10 septembre 2024 • Durée 40:35
This week I spoke with Bogdan Knezevic, founder of Kaleidoscope Bio, about optimizing biotech workflows and achieving milestones efficiently. Bogdan shared insights into how his platform helps companies manage research and development processes, reducing operational inefficiencies and saving time, resources, and money. He discussed the importance of setting clear goals, breaking down complex workflows, and avoiding shiny object syndrome (a common ailment among scientists). Bogdan also emphasized the value of keeping teams focused and aligned, leveraging automation, and integrating existing tools to minimize manual work. We explored how to empower teams, balance short-term and long-term goals, and pivot gracefully when needed. Additionally, Bogdan touched on the importance of understanding the true cost of operations and making strategic investments in tools that drive productivity.
01:10 Meet Bogdan Knezevic: From Childhood Dreams to Biotech CEO
02:22 The Frustration and Vision Behind Kaleidoscope Bio
04:01 Use Cases and Value Propositions for Biotech Companies
07:50 Empowering Teams and Setting Priorities
11:38 Balancing Short-Term and Long-Term Goals
18:22 Reducing Operational Overhead and Streamlining Processes
31:07 Common Mistakes and Lessons for Biotech Leaders
36:19 Book Recommendations and Closing Thoughts
Dream Big Dreams to Solve Big Problems: with Jon Hu, CEO and co-founder of Pepper Bio
Épisode 45
jeudi 15 août 2024 • Durée 39:40
This week I spoke with Jon Hu, CEO and co-founder of Pepper Bio, about his journey from pharma consulting and venture capital to founding a tech-enabled biotech company. Pepper Bio created an AI and machine learning platform accelerating drug discovery for untreatable diseases. In addition to the platform, Pepper is currently navigating their asset for liver cancer into phase 2 clinical trials. Jon highlighted the differences between tech and biotech, emphasizing the importance of dreaming big and aligning vision with employees. He shared insights on the importance of hiring, learning to learn, and overcoming challenges in transitioning from tech-enabled discovery to drug development. We also discussed Pepper Bio's computational platform, long-term strategy, and their Series A fundraising to support their clinical trial efforts. Jon’s personal story of family health challenges driving his passion for biotech underscored the company's mission to transform patient care.
Transforming Women's Health Through Innovation with Oriana Papin-Zoghbi, CEO and co-founder of AOA Dx
Épisode 36
mercredi 15 mai 2024 • Durée 27:12
This week I chatted with Oriana Papin-Zoghbi, CEO and co-founder of AOA Dx. Oriana shares insights on the challenges of fundraising and the importance of building a network for startup success. She highlights her career shift from biochemistry to economics and international relations, finally leading to her involvement in women's health diagnostics. Oriana emphasizes the significance of finding one's passion for excelling in their field and the role of previous startup successes in her current venture. I also loved learning more about AOA Dx's mission to revolutionize women's health diagnostics, focusing on unmet needs such as early ovarian cancer detection through innovative biomarker research. Oriana highlights the impact of leadership, resilience, and the pursuit of innovation in healthcare.
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Unlocking Leadership Potential in Biotech with Tony Martignetti, Founder and Chief Inspiration Officer of Inspired Purpose Partners
Épisode 35
mercredi 8 mai 2024 • Durée 38:00
This week, I chatted with leadership advisor, speaker, entrepreneur, and podcast host Tony Martignetti, MBA, CPC, Founder, and Chief Inspiration Officer of Inspired Purpose Partners. We both agree there’s a critical need for more comprehensive coaching and support for leaders in the biotech industry. Drawing from his diverse career that spans from art to finance and biotech, Tony shares insights into how leaders can become more grounded. He highlights his three Cs of grounded leadership - Connection, Curiosity, and Compassion - and underscores the significance of mental health, adapting to rapid change, and maintaining authenticity in the workplace. These qualities, he argues, are paramount for building strong companies and navigating the complexities of leadership in fast-evolving sectors like biotech.
The Future of Genomic Storage with Heather E. Williams, COO of Cache DNA
Épisode 34
mercredi 1 mai 2024 • Durée 33:05
In this episode, Heather E. Williams, PhD, MBA, MS, PgD, ErCLG, CG (ASCP) MB, the Chief Operating Officer of Cache DNA, chats about her career journey and the importance of always learning. Heather's passion for medicine and genetics has led her from childhood dreams of being like Dr. Quinn, Medicine Woman to training as a clinical laboratory geneticist and eventually becoming a COO. She talks about the value of making connections, grabbing every chance to learn, and how genetic results can really make a difference in patient care. Tune in to hear more about Heather's career story and get a sneak peek into what she does at Cache DNA.
Leaders as Change Agents with Catharine Smith, Executive Director of the Termeer Foundation
Épisode 33
mercredi 24 avril 2024 • Durée 37:07
This week, we had a conversation with Catharine Smith - the Executive Director at the Termeer Foundation. Catharine is passionate about supporting biotech founders in growing patient-centric companies. We are thrilled about the Termeer Foundation and have been delighted to witness the Termeer Fellows thrive through the support, training, and community that this organization provides. If you're interested in making a difference in human health through biotech, this episode is definitely for you.
From Dinos to Drugs with Isaac Stoner, CEO of Octagon Therapeutics
Épisode 32
mercredi 17 avril 2024 • Durée 35:36
In this episode, we chatted with Isaac Stoner, M.B.A., the CEO of Octagon Therapeutics. Isaac is known for his expertise in building small companies and embarking on adventurous missions such as recovering airplane black boxes (yes, you read that correctly!). He also hosts a science enthusiast networking group in Cambridge, where attendees drink beer and discuss science.
Embracing Change: Lessons from a Career in Biotech with Kyriakos Economides, PhD
Épisode 31
mercredi 10 avril 2024 • Durée 30:24
This week we sat down with Kyriakos Economides, PhD, VP of Translational Pharmacology at Werewolf Therapeutics. If there’s one constant in biotech, it’s change. We discussed the evolution of a career, rolling with the punches, and the importance of a solid clinical plan early in the drug development lifecycle.
Empowering Entrepreneurs with Leen Kawas, PhD, Managing General Partner at Propel Bio Partners
Épisode 30
mercredi 3 avril 2024 • Durée 38:43
This week, we had an insightful conversation with Leen Kawas, PhD, Managing General Partner at Propel Bio Partners. She shared her journey from studying pharmacy to founding a successful company (with a great exit) and now running a venture fund. She emphasizes the business case for the importance of DEI in the company leadership and in clinical trials. We also touched on tips on managing conflict in teams, fostering healthy communication, and the value of building a strong network and connections in the industry.
Bench to Boardroom with Andrew Fraley, PhD, CTO at Judo Bio & Entrepreneur in Residence at Atlas Venture
Épisode 29
mercredi 27 mars 2024 • Durée 46:01
This week, we had the pleasure of chatting with Andrew Fraley, PhD, Entrepreneur in Residence with Atlas Venture. We chatted about his journey from bench chemist to entrepreneur, and some of the things he learned in the process. He also shared valuable insights on structuring a pitch deck for those on the funding trail. Tune in to learn from Andrew's fascinating experiences and fantastic advice!
02:46 Transitioning from Academia to Entrepreneurship
04:03 Founding a Fund and Supporting Companies
05:03 Day-to-Day Life and Global Interactions
07:54 Building and Managing Effective Teams
13:11 The Importance of Diversity in Clinical Trials
18:53 Navigating the Current Economic Environment
25:12 Conflict Management and Effective Communication
31:10 Networking and Future Goals
36:05 Conclusion and Final Thoughts
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