Listen to learn about how dopamine neurons aren’t all the same, some neurons use dopamine to reduce negative behaviours, to increase or nothing at all. I’ll be talking to to Professor  Danielle who loves everything to do with navigation and Rajeshwar who is more of a dopamine specialist.

Links

Paper

Daniel.A.Domeck – lab website

Rajesh Awatramani – lab website  

Daniel A Dombeck twitter

Brain fm - Music to improve focus, mood and sleep

Use the code – brainexplained to get 20%

Support the podcast using Brain Fm or through Patreon or Buy Me a Coffee

Would love to hear from you, you can message through twitter, email or website .

I would love to hear about your research and I am always looking for people to come o the podcast and editors.

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This was a brilliant episode as I have long been looking into the research into a diagnostic test for Alzheimer’s Disease and dementia in general. I for a long time for a paper on diagnostic markers for Alzheimer’s Disease and demetnai in general because it is one of the roadblocks to help us understand and eventually cure these diseases. We still cannot diagnose Alzheimer’s Disease and most dementia’s until 15-20 years into the disease. And this paper is a big step forward looking at over 5000 proteins in the blood. So listen in to find out more.

NIA investigator page

https://irp.nih.gov/pi/keenan-walker

LinkedIn:

www.linkedin.com/in/keenan-walker-1268a6197

Paper:

https://www.ncbi.nlm.nih.gov/pubmed/37467317

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Episode Description

This episode is with Dr Titas is looking at retrograde zippering which is another way that neurons are able to correctly grow towards their correct final destination. What exactly does this system involve and how does this work? Listen in to learn all about it and we also explore why the C.elegans is a good model for neuroscience research- depending on the question you are asking.

I am also looking for individuals who would be interested in contributing to the blog. It would involve posts about the recent neuroscience that has been published preferably that week. You would try to explain the science in an easy to understand manner and would also want to delve into the significance of the findings. If this is something that interests you I would delighted to hear from you – please join the Brain Explained LinkedIn Contributors Page.

Linkto paper

Dr Titas Sengupta Twitter page

Link to website

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Listen in to learn more about arteriovenous malformations (AVM) a condition that leads to tangled blood vessels in the brain and spinal cord. This increases an individual’s likelihood of stroke. This week we will be exploring research that profiled the cells the blood vessels to find what changes occurred in these cells compared to normal samples. listen in to find out about this amazing research that could have wide-ranging implications.

Dr Ethan Winkler’s Twitter

Dr Ethan Winkler’s University Profile

The paper 

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Episode 11 is all about dancing molecules and how they could be used to help improve spinal cord regeneration. Listen in to learn how proteins that move faster are more effective with Professor Samuel Stupps.

Link to paper - https://www.science.org/doi/10.1126/science.abh3602

Professor Stupp’s Lab Website - http://stupp.northwestern.edu/

Prof. Stupp's Twitter- https://twitter.com/SamuelStupp

Useful Links:

https://www.facebook.com/simpsonquerreyinstitute

https://twitter.com/sqinstitute

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Research looking into the effects of phones and concussions. An odd mix but interesting. Listen in to learn more. We’ll be talking to Dr Prasanna.

Link to dissertation work - https://digitalcommons.lsu.edu/gradschool_dissertations/5339/

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Episode Description

Come and listen to the first special episode. A conversation with Dr Argel who I meet through the Society of Neuroscience. We talk about his journey into neuroscience and his work covering memory and studies into neuroinflammation and ketamine.

Lab website

Twitter account

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Want to know how we work well in teams? Then listen in to the latest episode exploring team flow with Professor Mohammed Shehata. Flow is our ability to enter that state where everything aligns and we are able to focus entirely on the task at hand.

- The eNeuro paper (the journal article here)

News coverage including The Times Magazine London (here), Psychology Today (here and here), IFL Science (here), TVN (here), Science Alert (here), SciShow News (here), and more (here).

- Mohammad Shehata’s LinkedIn

- Mohammad Shehata’s Twitter :@Mohamma_Shehata

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I’m back on track. Here is the next episode. In this episode we explore dopamine signalling in the brain. Why? Because dopamine is the main signalling compound in your brain for reward. So eat a bar of chocolate, get a new job, pass your exams and you get a dose of dopamine. But the research by Professor David Kleinfield is even more important because it shows that mice can control their release of dopamine, which might explain why we can do things that to others seem strange such as climbing mountains. That isn’t all, listen in to learn about his other research around the role of the vasculature in the brain and how senses work.

David Kleinfield lab website

The main paper

Two other interesting papers (which can be found on his website):

Ultra-slow oscillations in fMRI and resting-state connectivity: Neuronal and vascular contributions and technical confounds.

Brain microvasculature has a common topology with local differences in geometry that match metabolic load.

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 Episode 6 will be looking at  the brain regions involved in spirituality and Religiosity which is another word for religion. Therefore, I am extremely grateful to give you this unique episode. This episode will be of interest as over 90% of percent of people have some sort of spiritual practice and the other 10% will want to know how the brain is linked to spirituality and religion and what it means. Not only is this research interesting but it can help people make electrical stimulation therapy which is becoming even more common to reach the forefront. Neurospirituality course syllabus: https://neuromichael.com/neurospirituality-course/ Twitter for Professor Michael Ferguson: https://twitter.com/neuromichael/status/1433525429227372545 Biological Psychiatry article access: https://www.sciencedirect.com/science/article/pii/S0006322321014037?dgcid=author Neuromichael YouTube channel: https://www.youtube.com/neuromichael --- Support this podcast: https://podcasters.spotify.com/pod/show/brain-explained/support

Episode 5 dives traumatic brain injury a disease commonly received after too many blows to the head. How can we protect against this and how exactly is it studied in the lab. If that piques your interest then be sure to check out for we cover this and much more with Dr Andrew Pieper, a researcher in this field from the Harrington Discovery Institute.

Link to Dr Andrew Pieper’s Lab Website

Link to Dr Andrew Pieper’s LinkedIn

Link to paper

Brain Explained - Twitter

Brain Explained - LinkedIn

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Episode 4 of Brain Explained explores a new theory for understanding pain. Pain, its something we feel often and that many people chronically suffer from with an estimated 40% of people suffering from chronic pain and understanding pain would allow us to help them. That is where Dr Franziska Denk’s Research comes into play. For she is describing a new theory showing that a type of cell called a fibroblasts may be the key player in chronic pain. Listen to the episode to find out how.

Link to Franziska Denk’s lab website

Link to Twitter page for lab

Link to LinkedIn

Links to papers:

Fibroblasts– the neglected cell type in peripheral sensitization and chronic pain? - A systematic view on the current state of the literature.

A transcriptional toolbox for exploring peripheral neuro-immune interactions

Sensitization of Knee-Innervating Sensory Neurons by Tumour Necrosis Factor-α Activated Fibroblast-Like Synoviocytes: An in Vitro, Co-Culture Model of Inflammatory Pain.

Resources:

https://www.coursera.org/learn/statistical-inferences

https://www.franziskadenk.com/resources

https://rna-seq-browser.herokuapp.com/

https://rna-seq-browser.herokuapp.com/

http://mousebrain.org/genesearch.html

https://panglaodb.se/

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Today is a unique episode. It is the first time I will have people interviewed on the show. I talked to both Professor Arne.D.Ekstrom and Sarah Seger who is a PhD student in his lab who did a lot of the work for the paper which is titled, ‘ Memory-related processing is the primary driver of human hippocampal theta oscillations.

Lab website

Paper

Twitter page

Podcast website

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Episode 3 of Brain Explained explores neuroimaging and blood supply, cleaning in the brain with Professor Farshid Sepherband from The University of Southern California. Why are spaces imaged in the brain and how are they linked to daily life and disease? Listen to find out. In Episode 3 we discuss his recent research into the neuroimaging of the clearance system and blood supply. We discuss his research, opportunities and as always there are a lot of interesting insights.

Twitter

LinkedIn

Further links:

Link to Farshid Sepherband’s lab website

Link to papers: Perivascular space and BMI/ time of day/ gender, Perivascular space and Parkinson’s Disease, Perivascular space and Alzheimer’s Disease.

Neuroimaging resources:

LONI pipeline(for image analysis) :

Open source python group for neuroimaging:

Introduction to biomedical imaging:

To learn about basics MRI physics:

For MRI related questions:

MRI communities - with a lot of resources:

ISMRM:

OHBM:

Farshid’s favourite neuroscience online course:

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Episode 2 of Brain Explained explores the brain circuits involved in language and memory with Professor Christopher Petkov of Newcastle University. Chris’s work looks at the brain regions involved in language and memory in humans and macaques. We discuss his work, how it is being practically used, the opportunities you have to get involved in this area of research using real data and more.

Link to Chris Pektov's Laboratory Website.

Link to paper

Current Research in Neurobiology 

Editorial Introduction to Current Research in Neurobiology.

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A short introductory episode detailing what Brain Explained is all about. 

Twitter - https://twitter.com/Br_Explained

Linkedin - https://www.linkedin.com/company/brain-explained-podcast

Email - brainexplained@outlook.com

Music

Beauty Flow by Kevin MacLeod

Link: https://incompetech.filmmusic.io/song/5025-beauty-flow

License: https://filmmusic.io/standard-license

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This episode is a short one because I could not find the other episodes even after contacting Zoom.

We will be discussing the paper titled. Non-invasive In Vivo Brain Astrogenesis and Astrogliosis Quantification Using a Far-red E2-Crimson Transgenic Reporter Mouse

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Today, I’ll be talking to Professor Scott Waddell and is research into memory in the Drosophila the commonly used fly in science research. Memory is one of the most interesting topics in the most interesting field which is neuroscience and this episode will not disappoint.

https://www.dpag.ox.ac.uk/team/scott-waddell

https://twitter.com/ScottishWaddell

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COVID may be something we do not want to think about but it is important that we carry on trying to understand the effects of this devastating virus. With Dr Daniel Martins de Souza we will be looking into the neural effects of COVID. Listen in to find out how it effects the brain.

Link to Paper

Link to Dr Daniel Martins de Souza

Link to Brain Explained Blog

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Microglia are the brain’s defense system and cleaning system and so are incredibly important for the normal functioning of the brain if you want to learn more about these fascinating cells then be sure to listen in to this episode of Brain Explained.

Dr David Menassa’s Twitter

Dr David Menassa’s lab page

The paper

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Come at listen to the latest episode of Brain Explained where we explore research looking into blood flow across the brain. A relatively new and very important area o research that is opening up so many findings.

The paper

Dr YongSoo lab website

Dr YongSoo’s Twitter

Brain Explained website

Brain Explained Twitter

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New neurons have been discovered that generate fever and illness in the brain. Want to learn more about them and how they where discovered then listen in to the latest podcast episode.

Dr Jessica Osterhout's Twitter
Dr Jessica Osterhout's University Profile
The Paper
Brain Explained Twitter
Brain Explained Website

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Want to learn about how genetic differences might affect your brain then come and listen to the most recent episode of Brain Explained where we explore just that. You’ll learn about the first-ever long-term study in this area and it does not disappoint. It is truly something to look forward to.

Laboratory Website

Paper

Brain Explained Twitter Account

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