Big Picture Medicine – Détails, épisodes et analyse

Dr Aengus Tran is the CEO of Harrison.ai — an Australian radiology AI startup who have raised $160M.

Harrison.ai just released their radiology foundation model, Harrison.rad.1. And it's really good.

0:00 Intro

2:25 I'm glad I didn't found my startup in the US

4:21 Partnering with a clinical operator is key

7:28 Scrappy stories from the early days

11:17 Where human radiologists outperform AI (zero-shot learning)

17:23 Big bets on the future of radiology

21:18 What happens when GPT-8 arrives?

25:29 How can AI reach suprahuman radiology performance?

28:58 What boss moves did you make?

Links

Harrison.ai: ⁠https://harrison.ai⁠

Dr Mustafa Sultan: ⁠https://www.musty.io⁠

Michael Meucci (CEO) transformed Arcadia — formerly a mid-sized consultancy into a healthcare platform with $100M of Annual Recurring Revenue. How?

Lots of smart moves, including becoming really good at enterprise healthcare selling. Here's how he did it.

Links

Arcadia: https://arcadia.io/

Dr Mustafa Sultan: https://www.musty.io/

Dr Jared Dashevsky writes Healthcare Huddle (acquired by Workweek). He's scaled to over 30,000 subscribers. And it was pretty simple.

Here are 12 frameworks that work for healthcare content creation (and mistakes to avoid).

0:00 Intro

1:14 Consistency is king; systematise it

7:40 McKinsey reverse pyramid principle for writing

9:10 You need to have a unique/controversial take

11:41 Content for network building

15:51 Lean startup thinking does not work for content

20:35 Nobody cares about errors

25:52 Injecting personality is a competitive advantage

29:32 Boring content will make you rich

34:13 Don't make a useless audience; acquire data

41:19 Lessons from Jerry Springer

45:18 Hyperoptimisation paradox

48:49 Do things that don't scale

Links

Healthcare Huddle: https://workweek.com/brand/healthcare-huddle/ Dr Jared Dashevsky: https://twitter.com/jareddashevsky Dr Mustafa Sultan: https://www.musty.io/

What's the difference between UK and US medical training?

Dr Ikram Haq trained at Imperial College Medical School, interning at McKinsey before starting training at the Mayo Clinic in the US — considered one of the best hospitals in the world.

We talk about the difference between US and UK medical training, how Ikram got to where he is — covering both the high level philosophies and granular details — as well as how he deals with failure.

I hope you enjoy.

You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Can you automate therapy?

Ross Harper studied both Neuroscience (Cambridge) and Mathematical Modelling (UCL) — combining the two into his lovechild: Limbic — an AI therapy assistant.

We talk about the challenges of working in mental health, different business models in the area and how Ross sold his face to pay off his uni debt.

I hope you enjoy.

You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

How do you make good decisions in health leadership?

Professor Sam Shah is founder of the Faculty of Digital Health, Chief Medical Strategy Officer at Numan and former Director of Digital Development at NHS X.

He has extensive experience in consulting, health policy and healthtech. We talk about good decision making in health leadership roles, how to make clinicians digitally proficient, and some of his failures along the way. I hope you enjoy.

You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

How can you extend life?

Professor Tom Kirkwood is Emeritus Professor at Newcastle University where he headed the Institute for Ageing and Health. He delivered the famous Reith Lectures and was awarded a CBE in 2009.

Perhaps most famously he put forward the ‘Disposable Soma Hypothesis’ — which postulates that the body has a limited budget of resources and energy. It must therefore make a compromise between living longer (longevity) and activities which will help it reproduce.

Interestingly, he also invented the INR in the 80s, which is a blood test used everyday by doctors to measure the clotting of a patient’s blood.

We talk about the disposable soma theory, how calorie restriction may extend lifespan, anti-ageing interventions which Prof Kirkwood finds interesting and how you would design a trial to show the efficacy of an anti ageing drug.

You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

What are the pros and cons of VC funding as a doctorpreneur?

Dr Fiona Pathiraja was a Consultant Radiologist at UCLH and is now Founder and Managing Director of Crista Galli Ventures — a pan-European healthtech fund. She also holds an MBA and an MPH.

We dive into her story, Venture Capital and she gives loads of valuable advice for doctorpreneurs. 

I hope you enjoy.

Crista Galli Ventures: https://www.cristagalli.com

You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

So it's your first day as Health Secretary — what do you do!?

Richard Sloggett was former Special Advisor to the Health Secretary (Matt Hancock) during which he worked across public health, the NHS and social care. He’s also Senior Fellow at the think tank Policy Exchange and has been named one of the 100 most influential people in healthcare policy by the Health Service Journal.

Richard has also recently founded a global healthcare policy research centre: Future Health. The Centre is researching health and economic opportunities in building more resilient and preventative healthcare systems enabled by new technologies: https://www.futurehealth-research.com

We talk about whether healthcare is as unique as medics like to think, Richard’s learnings from his time as special advisor and his specific recommendations for getting clued up on health policy.

I hope you enjoy.

You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

How can we use models to diagnose patients with rare diseases earlier?

Rudy Benfredj is Co-founder and CEO of Mendelian; who are helping doctors find and diagnose rare disease patients earlier.

Rare diseases are individually rare, but collectively quite common — they affect 1 in 17 people. With 8000+ rare diseases and some only affecting a handful of people across the globe — rare diseases take an average of 7 years to diagnose — which is dubbed the diagnostic odyssey.

Rudy is super interesting and I pick his brain about how artificial intelligence can be used help reduce the diagnostic odyssey in rare diseases. I hope you enjoy.

You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io