Explorez tous les épisodes du podcast Authentic Biochemistry
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| Authentic Biochemistry. Sarcopenia XIV. Dr Daniel J. Guerra 08October24. | 09 Oct 2024 | 00:53:46 | |
References Biosci Rep. 2022 Jun 30; 42(6): BSR20211854 Bone. 2022-11-01, Volume 164, Article 116539 Satie. E.1890. Gnossiene No 1 https://open.spotify.com/track/4820SC1xnUaabzzYQTDkP2?si=cd7a6ed41db24a17 Bach. JS 1726..Cantata BMW. 169 https://open.spotify.com/track/50dM4aKwuItH59JC96Y0bI?si=b3d8f5c80b3f48b7 | |||
| Authentic Biochemistry Podcast. Sarcopenia XIII Lipid Utilization via Perilipin/CD36 and Spatiotemporal Framing. Dr Daniel J Guerra 07OCTOBER24 | 08 Oct 2024 | 01:02:18 | |
References Biosci Rep. 2022 Jun 30; 42(6): BSR20211854 Nature Reviews Endocrinology 2018. volume 14:452–463 Bone. 2022-11-01, Volume 164, Article 116539 Beethoven LV. 1806. Violin Concerto in D Major OP 61 https://youtu.be/rhdXr9l5gPM?si=0WcFfHzKajylaUBA Hunter-Garcia. 1973 Row Jimmy on [Wake of the Flood;lp] https://youtu.be/B4k9XfHBVEE?si=T3mXTER0Nvh2cccG
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| Authentic Biochemistry Podcast Sarcopenia V. Dr. Daniel J. Guerra 16.9.24 | 17 Sep 2024 | 00:49:03 | |
References HORMONES 2013, 12(2):172-191 Eur J Endocrinol. 2017 176(5): R235–R246 Amino Acids. 2012 Oct;43(4):1803-7 Cell Metabolism 2020 31472-492DOI Kirwain, D. 1972 "Dust" Fleetwood Mac [Bare Trees lp.] https://open.spotify.com/track/2yE8gE3zBfflRklTKIlpiv?si=d1cbe70445c34fa6
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| Biochemical Mosaic III. Inflamasomes c.11 A Dialectical Event Ontological conciliantus contrarion perspective.DJGPhD.3April24.Authentic Biochemistry Podcast. | 04 Apr 2024 | 00:29:22 | |
REferences Guerra, DJ. 2024. Biochemical Mosaic III lectures. https://podcasts.apple.com/us/podcast/authentic-biochemistry/id1454408625 Dvorak, A. 1879. Romance in F minor, Op. 11, (B. 39). https://youtu.be/XZTeavJ9frA?si=18LFzAQ9FKfrQ_16 Dylan, R. 1975. "Tangled up in Blue" performed by Gerry Garcia Band (live;1977) https://youtu.be/8Aw7FW1Frjs?si=jURQC3jBWFPirSh8 Betts, R. 1972. "Blue Sky" Allman Brothers (Eat a Peach.lp.) https://youtu.be/wwyXQn9g40I?si=15Cv6iJxR82VAb_3 | |||
| Biochemical Mosaic III.c.10 Atherogenesis and neointma formation are associated with sphingomyelinase membrane raft NOX aggregation during inflammasome activation.DJGPhD.2April24 | 03 Apr 2024 | 00:29:47 | |
References J Lipid Res. 2022 Dec; 63(12): 100298. Mol Cells. 2020 Aug 31; 43(8): 749–762. Bach J.S. 1727. St Matthew Passion, BWV 244. https://www.youtube.com/live/3fP-rET0kFI?si=ZX-edMPg1wBA_5mh Squire, Chris. 1978. "You Can Be Saved" Yes. https://youtu.be/0TNzPHoVlz8?si=bFMp6w4T2SL6XxS4 | |||
| Biochemical Mosaic III.c.9 Clinical associations of inflammasome mediated pathophysiology linked to epigenetic methylation patterning and DNA repair. DJGPhD.1April24. | 02 Apr 2024 | 00:30:00 | |
References Redox Biol. 2020 Apr; 31: 101482 Nat Rev Microbiol. 2009 Feb; 7(2): 99–109. J Neuroinflammation. 2019; 16: 236. Front Pharmacol. 2021; 12: 643254. Biber, H. 1676. "Passagalia" por solo violin https://youtu.be/sgcR183f8gA?si=ovfSbdg6WsfuIiTw McBroom, A. 1976. "The Rose" Conway Twitty https://youtu.be/cO59ITNCxzk?si=ueMmXtzMNH4YeQ_w Hunter-Weir. 1970. "Sugar Magnolia" American Beauty L.P. https://youtu.be/ei5EmN2HmVI?si=6ZrBBPmu3cMyMOAO | |||
| Biochemical Mosaic III.c.8. S. aureus clearance via dual pyroptosis and necroptosis salientsand the control over the hyperinflammatory axis of clinical disease. DJGPhD.31.3.24 | 01 Apr 2024 | 00:29:19 | |
References Cell Reports 2016.Volume 16, Issue 8, 23 Pages 2219-2230 Front Immunol. 2020; 11: 621733 Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E961-E969 | |||
| Biochemical Mosaic III.c.7 Convergence of Inflammasome molecular patterning obtains PRR-like sequalae that are hypo-modified epigenetically in multple Human pathophysiologies | 28 Mar 2024 | 00:30:00 | |
References Int J Mol Sci. 2021 Jul; 22(14): 7580. Trends Biochem Sci. 2023 Apr;48(4):331-344 Immunology. 2020;159:142–155 Curr. Opin. Immunol. 2020;62:39–44. Nat. Rev. Mol. Cell Biol. 2019;20:569–570. Lennon-McCartney. 1963. "This Boy" https://youtu.be/lW5D7HpYhBU?si=mHyiFng3rd3pukob Lennon-McCartney.1966. "And your Bird Can Sing" https://youtu.be/sOUlbredoUM?si=nPB64c8GS4joYx9G Lennon-McCartney 1969. "Let it Be" https://youtu.be/QDYfEBY9NM4?si=H6t6bwrv3vUNWoDj Vivaldi, A. 1715 "Gloria" https://youtu.be/RMHguvZPcqQ?si=igPXLKL9O0YbRWKz | |||
| Biochemical Mosaic III. c.6. S auereus induced inflammasome activating pyroptosis circumvents immune clearance and ARDS pulmonary chronic activation share similar hyperinflammatory presentation.DJGPhD | 27 Mar 2024 | 00:30:00 | |
References Front Immunol. 2019; 10: 1309 Immunity. 2018 Sep 18; 49(3):413–426.e5. Front Immunol. 2020; 11: 621733 Infect Immun. 2013 Dec; 81(12): 4478–4489. Immunity. 2023 Nov 14;56(11):2523-2541.e8. Harrison, G. 1969. "Here Comes the Sun" Abbey Road Lp. Beatles https://youtu.be/GKdl-GCsNJ0?si=xUqwi3Q7Ne694ruD Mozart, WA. 1775. Violin Concerto No.3 in G major, K. 216 https://youtu.be/j7Z6gouAVCc?si=xVwtNKAWDEDdtKMV Parsons, G. 1965 "Brass Buttons" Poco: Crazy Eyes Lp. https://youtu.be/CpFytplzLhI?si=vw08Gut3E-otgA9x | |||
| Biochemical Mosaic III. c.5. Gal3 and NRLP3 inflammasome coordinate inflammation via IL-1Beta convertase activation that is associated with NAFLD and NASH and inhibition of ABCA1 cholesterol efflux. | 25 Mar 2024 | 00:29:20 | |
References Infect Immun. 2013 Dec; 81(12): 4478–4489 Cell Cycle. 2022; 21(11): 1121–1139. The Journal of Nutritional Biochem.2023.Volume 112, 109217 Lightfoot, G. 1964. "Early Morning Rain" https://youtu.be/ZFJ5Bj_put0?si=m1Ue7rFfk_ggSLR3 Simon ,P. 1968. "Old Friends" SImon and Garfunkle Bookends LP. https://youtu.be/7A76lTte8qE?si=rfk3Q6wTA6Nsiok7 Mozart, WA. 1782 Serenade in C. Minor K.388. https://youtu.be/R6iSGBNdqSw?si=S2eGPmcySUhw4uvU | |||
| Biochemical MosaicIII. C.4. My oppositional dialectic and episteme- metaphysical discourse on method+ Gal3 as proinflammatory lectin may not uniformly correlate with pathobiochemical events. DJGPhD. | 23 Mar 2024 | 00:30:00 | |
References Guerra, DJ. 2024. Uncollected writings. The Journal of Nutritional Biochemistry 2023. Volume 112, February. 109217 Walker, Cindy.1950 Blue Canadian Rockies. Cover "the Byrds"(1969). https://youtu.be/nzOHtU8Sb3c?si=5GAj7VPzIr7o0OO_t Heinichen J. D. 1711 (?)Concerto in A minor for violin https://youtu.be/V-E25Q-wjwc?si=bbWdZTNEUPGitY-S | |||
| Biochemical Mosaic III c.3. Bacterial glycosphingolipid mediated inflammasome activation and the Galectin:NLRP3 interaction pathophenocopy oxy-mtDNA TLR induction.DJGPhD.21.3.24 | 22 Mar 2024 | 00:28:50 | |
References Front Immunol. 2020; 11: 591803 Am J Gastroenterol. 2004 Nov;99(11):2147-9. Biochem Biophys Res Commun. 2005 Dec 16;338(2):1031-6 Front Immunol. 2019 Jun 7;10:1309. FASEB J. 2021 May; 35(5): e21439. Hildegard von Bingen 1150.- "Canticles Of Ecstasy | |||
| Biochemical Mosaic III. C.2 A Non-canonical autophagic inhibition of NLRP3 inflammasome mediated inflammation in UVB-treated human keratinocytes.DJGPhD. 20.3.24. | 21 Mar 2024 | 00:30:00 | |
References Front Immunol. 2019 Jun 7;10:1309. JBC 2024 . March.Article in Press FASEB J. 2016 Dec;30(12):4202-4213. Nat Rev Gastroenterol Hepatol . 2020 Feb;17(2):93-110 Bach , JS. 1731. Piano Partita No. 2 In C Minor, BWV 826 https://youtu.be/f-OdOuNZciQ?si=AmFtC5CX3x2ndzdV Slade,Mann, and Rogers. 1975 "Time is Right" Manfred Mann https://youtu.be/jzJIej8h5q4?si=3-aCFe0tqur4lfX1 | |||
| Sarcopenia IV. The CH20 Signaling Metabolome Circuit Involving the CNS, Liver, Adipose and Skeletal Muscle. Authentic Biochemistry Podcast Dr. Daniel J. Guerra 14.9.24 | 15 Sep 2024 | 01:02:42 | |
Guerra, DJ. 2024. lecture notes Leach, Donovan. 1967 "Mountain Jam" Allman Brothers https://youtu.be/w9ZubobGMLs?si=uHLon1CvCiCSiqtX | |||
| Biochemical Mosaic III. C.1. Inflammasomes. DJGPhD.19.3.24 Authentic Biochemistry Podcast | 20 Mar 2024 | 00:30:00 | |
References Immunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8 JBC 2024. March. Article in Press https://doi.org/10.1016/j.jbc.2024.107173 Schmelzer. J. H.1664 Sonatae unarum fidium. https://youtu.be/fB8G39y1uCA?si=ZMG2Zv9eKF3go0qR Hayward, J. 1967 "Tuesday Afternoon" Moody Blues https://youtu.be/fB8G39y1uCA?si=ZMG2Zv9eKF3go0qR Hayward, J. 1970 "Question" Moody Blues https://youtu.be/NP9iOqdxS8c?si=rfI3lzy0HhcffkWT | |||
| Biochemical MosaicII.Book2.C.13.Dialectical event ontologies involving CNS plasmalogen and sphingolipid interlocution and the universality of Mozart and the Beatles. DJGPhD.17.3.24.Authentic Biochem. | 18 Mar 2024 | 00:30:00 | |
REferences Dr. Guerra. 2024.Previous Authentic Biochemistry Mosaic II lectures in the series Kant, I. 1790. Critique of Judgment. Mozart, WA. 1788. Sinfonie C-Dur KV 551 (»Jupiter«) https://youtu.be/6RbKWhr0o1c?si=xkt3QMG5aud__zLN Beatles. 1965. "Rubber Soul" https://youtu.be/kfSQkZuIx84?si=8QFvenLD4k8KLJD3 | |||
| Biochemical Mosaic II.Book 2. c.12 Adduced mTORC mediated glycerol-sphingolipid enzyme mRNA transcriptome association with Plasmalogen apodiction of myelination.DJGPhD.16.3.24 | 17 Mar 2024 | 00:29:45 | |
References Developmental Cell 2022. Volume 57, Issue 6, 28 March Pages 691-706 Cell Rep. 2014 Feb 13; 6(3): 541–552. Dr Guerra: graduate lecture notes Mozart, WA 1791.Requiem in D Minor, K 626 https://youtu.be/YaH3zI0bYkM?si=X1yv50zY6nKTZmV9 Lennon/McCartney.1964 "I Don't Want to Spoil the Party" https://youtu.be/zqVDvLDLsjI?si=K1ve_5zJLZjqclsb | |||
| MosaicII,Bk.2.c.11 Squalene monooxygenase (SM) stabilization due to plasmalogen pathway fatty acid reductase deficiency promotes SM epoxidase alternate activity thus lowering24OHCHOL-LXR-myelination. | 14 Mar 2024 | 00:29:52 | |
References Dr Guerra-Graduate lipid biochemistry lectures Biochem J. 2022 Sep 30; 479(18): 1917–1940 Front Cell Dev Biol. 2022; 10: 946393. Nat Commun. 2019; 10: 97. Lennon-McCartney 1965. "Ive Just Seen a Face" https://youtu.be/m8LbJfC0SYM?si=gl_URu_yPTn9iZSd McShee, J./Traditional/Pentangle.1969 "Light Flight" https://youtu.be/2tyVezuUtCA?si=THxBJ0reUETkwDLa Mozart, WA. 1785.Piano Concerto No. 21 in C Major, K. 467 https://youtu.be/whTEVQ2OizI?si=YDMhOhlwmpKYqK-t | |||
| Biochemical Mosaic II. Book2. c.10.Plasmalogen mediated oxy vs epoxy sterol synthesis may control cns inflammation and myelination given acid-catalyzed transacetalization sequalae.DJGPhD.12March24 | 13 Mar 2024 | 00:29:28 | |
References Front Cell Dev Biol. 2022; 10: 946393. Adv Exp Med Biol. 2024:1440:149-161 Mozart, WA..1786.Horn Concerto in E-flat major # 4 KV 495 https://youtu.be/MMjqU461WpI?si=o2OWIijoe-mbF-pM Sebastian, J. 1968 She's a Lady https://youtu.be/xyFdzevDOHg?si=wgmv5z_jGrtA9x7c | |||
| Biochemical Mosaic II. Book2. c.9. Plasmalogen regulation of composite ruling over prescriptive organization of cellular-biochemical phenomena includes florid mediation of the CNS.DJGPhD.11MARCH2024. | 12 Mar 2024 | 00:29:38 | |
References Journal of Cell Science 2019.Vol.132(6), 223016. Brain Research Bulletin 2023.Volume 194, March. Pages 118-123. Beethoven, LV. 1806. Violin Concerto D major, Op. 61 https://youtu.be/_hXdjRYELGw?si=0q5_qJCZu_zAZWoE Berry, C. 1956. "Roll Over Beethoven" ; as performed by the Beatles 1963 on LP "With the Beatles" https://youtu.be/Hz5jXwOXgKQ?si=FASk6PG2SAsEkrvP | |||
| Biochemical Mosaic II.c.8 Cell death and CE-circ RNA vs.miRNA in Hepatocellular carcinoma: the spectre of AGPS et al. DJGPhD. 10March24.Authentic Biochemistry. | 11 Mar 2024 | 00:29:49 | |
References Cell Death Dis. 2020 Dec; 11(12): 1065. Genome Res. 2000 Oct; 10(10): 1445–1452. https://www.genecards.org/cgi-bin/carddisp.pl?gene=NIPBL Genes Dis. 2022 Jan; 9(1): 116–127 Schubert, F. 1824. Quartet 14 in D minor, D 810, "Death and the Maiden" https://youtu.be/XF_6vSlmm4w?si=CGTn3R6Tkn6LsMLv Browne,J. 1993. "Sky Blue and Black". https://youtu.be/Ty1I6dtC2zc?si=QHuwDiQUDh-4S5VP | |||
| Biochemical Mosaic II.c.7. Fatty acid desaturation and mole% PC/PE/PL/CER are elevated via circRNA in Medublastoma while AGPS increased circRNA's in thyroid cancer.DJGPhD.7Mar24. Authentic Biochem. | 08 Mar 2024 | 00:29:49 | |
References Acta Neuropathologica Communications 2023. volume 11, Article number: 38 Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798 Front Mol Biosci. 2022; 9: 925389. Front Cell Dev Biol. 2021; 9: 636838 Oncol Lett 2018. 15: 7889-7899. Saint-Saëns, C. 1886. Symphony No 3 in C minor, Op 78 https://youtu.be/ZWCZq33BrOo?si=8hQ01E9jfp0eU07o Winwood,S. 1969. Had to Cry Today (Blind Faith) https://youtu.be/Z4Yo_VbGdMg?si=tWz0_qnG5Nsx5qxX | |||
| Biochemical Mosaic II.c.6 Meduloblastoma is linked to plasmalogen and circ RNA phenomena that are pathophenocopied in other cancers. DJGPhD.5.Mar24.Authentic Biochemistry | 06 Mar 2024 | 00:30:00 | |
References Acta Neuropathologica Communications 2023. volume 11, Article number: 38 Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798. Int J Med Sci. 2022; 19(6): 975–985 Nature Communications 2022. volume 13, Article number: 1508 Lassus. O. 1578. Requiem - Missa pro defunctis (4vv) : Offertorium | |||
| Biochemical Mosaic II. c.5 Peroxisomal plasmalogen biosynthesis may regulate transcriptomic and proteomic sequalae to plasmamembrane mediated signal transduction. DJGPhD.4March24. | 04 Mar 2024 | 00:30:00 | |
References Front Physiol. 2021; 12: 730829. Non-coding RNA Investig 2017. 1:5. Genome Biology 2011. volume 12, Article number: 236 RNA Biol . 2021 Nov 12;18(sup2):574-585. Hunter. R. 1975. "Cruel White Water" https://youtu.be/T-oBD3F74Nk?si=zsrEBN0JKan_FXdH | |||
| Authentic Biochemistry Podcast Sarcopenia.C.3 AMPK Control over Pyrimidine and Purine biosynthesis via mTORC. Dr. Daniel J. Guerra. 11Sept24 | 12 Sep 2024 | 00:51:58 | |
References Experimental & Molecular Medicine.2016. volume 48, 224 Nature Metabolism 2023. volume 5, pages 277–293 Nature Reviews Drug Discovery 2019. v18. : 527–551 Pisendal . JG. 1730's. Violin Concerti. https://open.spotify.com/album/6dC3dq8i6rDeeKtz5LyhFZ?si=jUsRMIraR7-zO5o0UQGMdw
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| Biochemical Mosaic II. c.4. Peroxisomal biogenesis and AGPS-mediated plasmalogen synthesis involve circular RNA species that alter microRNA and mRNA expression in human cancers. DJGPhD.3MAR24. | 04 Mar 2024 | 00:29:48 | |
References Genome Res. 2004 Nov;14(11): 2245–2252. Int J Med Sci. 2022; 19(6): 975–985. Oncol Lett. 2018 May; 15(5): 7889–7899. Cell Death Dis. 2020 Dec; 11(12): 1065. RNA Biol . 2021 Nov 12;18(sup2):574-585 Bach, J Christian. 1775. Sinfonie Concertante https://youtu.be/S8NPgouJ5uk?si=_azSWNelNFRA2ai5 | |||
| Saturday Night Authentic Biochemistry The Agentic operator as metaphysical metaphor in metabolic regulation. DJGPhD.2March 2024. | 03 Mar 2024 | 00:30:00 | |
References Dr Guerra Archives: Graduate Biochemistry Lecture notes and syntheses Simon, P. 1969. The Boxer. https://youtu.be/l3LFML_pxlY?si=Nv5-mSzRu6fHP8Sr Boccherini, L. 1760. 7. Cellokonzert https://youtu.be/NSU6Ylxaobs?si=PZW0S3mWl25RwnE2 | |||
| Biochemical Mosaic II. c.3 Plasmalogen metabolism is coherently associated with peroxisomal integrity and replication. DJGPhD.01March 2024 Authentic Biochemistry. | 02 Mar 2024 | 00:30:00 | |
References Oncol Lett. 2018 May; 15(5): 7889–7899 Nat Genet. 1997 Apr;15(4):369-76 Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118609 Protein Cell 2018. 9, 196–206 Brain Research Bulletin 2023. 194: 118–123 The Moody Blues. 1968. "In Search of the Lost Chord" https://youtu.be/k5UdP-SFNgY?si=zDboUgA2LDi3E7m1 | |||
| Biochemical Mosaic II. C.2. Plasmalogen and PAF biosynthesis in relation to glycerol lipid and intermediary subcellular metabolism.DJGPhD.27.2.24 | 28 Feb 2024 | 00:29:59 | |
References Guerra: graduate biochemistry lectures Chopin, F. 1830. Nocturne E Flat Major Op.9 No.2 https://youtu.be/tV5U8kVYS88?si=MKxfguVRI6hhQeMO Winwood, Wood and Capaldi 1967. Dear Mr Fantasy. Traffic. https://youtu.be/sS_eHdqcrM8?si=95X9RWJD2Q4w456S | |||
| Biochemical Mosaic II. Plasmalogens & other ether lipids. c.1 DJGPhD.26.2.24. Authentic Biochemistry Podcast | 26 Feb 2024 | 00:29:36 | |
References Cell Metab. 2014 Mar 4; 19(3): 380–392. Protein Cell 2018. 9, 196–206. Membranes 2023, 13(9), 764. Debussy , C. (. 1890;1905) Clair de lune. https://youtu.be/6zzWnxuQPWI?si=gcEAKpbgc9xO8esf Morricone. E. 1968. "Once Upon a Time in the West" https://youtu.be/j5eQ9UTmDLo?si=-eUjJ1s9hAd6fpwz Schubert, F. 1825. Ave Maria https://youtu.be/2H5rusicEnc?si=LcYisCODwtGgjjVx | |||
| A Dialectical Interlocution with Mozart. DJGPhD.24.2.24 Authentic Biochemistry Podcast | 25 Feb 2024 | 00:28:52 | |
References Mozart.WA 1782. Fantasie in D minor. K.397 https://youtu.be/OYiz_u0tDwM?si=0dP736rTEkb4sauL 1785.Piano Concerto 22 in E flat Major.K.482 https://youtu.be/EJYPnrYNt8A?si=VqgS-PNw2bnbIFBj 1788.Divertimento in E♭ major, K. 563. https://youtu.be/2N4hHhTu4pw?si=p-VwHTTOK5ixFWfk 1787. Eine kleine Nachtmusik, K. 525. https://youtu.be/156u4nV2uGE?si=bRqysFpbi-6j0jMk | |||
| Biochemical Mosaic I. CODA. Membrane lipids function as biosensors for pKa's of phosphonoester anionic charge density with polybasic protein domains to mediate communication including transcription. | 24 Feb 2024 | 00:29:53 | |
References J Biol Chem 2017 292: 20481. Nature Cell Biology 2019. volume 21, pages 338–347 Rossini.G. 1829. William Tell Overture. https://youtu.be/z7Tj2SzToHI?si=QUXkj3NzqF17Zq60 Vivaldi, A. 1712. Concerto in D Major. RV 212. https://youtu.be/l21_9KKy1Pg?si=9HSMxRj7huJF1B8j | |||
| Biochemical MosaicI.c.13 Phosphatidic acid as key lipid intermediary of membrane secretion signalling and cellular intracommunication via kinase cascade and transcriptional regulation.DJGPhD.22.2.24 | 23 Feb 2024 | 00:29:55 | |
References Biomedicines 2023, 11(7), 1804 BMC Biology. 2011. 9:85 Cancer Res. 2011 Jan 15;71(2):293-7. FEBS Lett.2019.593.17:2428-2451 Verdi, G. 1841. Nabucco Overture https://youtu.be/OseGETWEnCo?si=LhiIQV-N0-_Z_s-s Lennon&McCartney. 1966 "For No One". Beatles: Revolver. https://youtu.be/sep5E3ssXLQ?si=WLtMrP-Xq279qZXl | |||
| Biochemical Mosaic I. c.12. The porosomal secretory system requires anioic lipids including phosphatidic acid. DJGPhD.21.2.24 | 22 Feb 2024 | 00:29:33 | |
Dr. Guerra: membrane graduate biochemistry lecture notes J Cell Mol Med . 2015 Jul;19(7):1427-40 Langmuir, 2018, 34 (1), pp 530–539 Elgar, E. 1900. The Dream of Gerontius https://youtu.be/rnwmVypRY-g?si=CxF8tZrfRR-uWdhn
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| Biochemical Mosaic I.c.11. Glycerolipid metabolism coupled to mTORC1 enzyme phosphorylation necessarily involves a complete analysis of membrane lipid molecular species distribution.DJGPhD.20.2.24 | 20 Feb 2024 | 00:29:56 | |
References Nature . 2019 Nov;575(7782):361-365. Adv Biol Regul. 2017 May:64:39-48 J Biol Chem. 2013 Apr 5; 288(14): 9933–9945 Redox Biology.2017. Volume 11, April. Pages 622-630 Biochim Biophys Acta. 2011 Jun;1811(6):377-85 Dr Guerra: lipid lectures archives Schubert, F. 1816. Symphony #5 https://youtu.be/OHkot1TmvZU?si=uYtQfxUegl3KrkRK Newman, L Darby K. 1954. Marilyn Monroe. The River of No Return https://youtu.be/dLzeHkEQe9g?si=nXMd20gstc3vVdgl | |||
| Sarcopenia C.2 Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 10Sept24 | 11 Sep 2024 | 00:57:47 | |
References Acta Physiologica (Oxford)2024. V.240.Issue 3 e14107 Hum. Mol. Genet. (2016) doi: 10.1093/hmg/ddw252 Amino Acids. 2016 Aug;48(8):1793-805. European Journal of Applied Physiology 2013, Volume 113, Issue 4, pp 987–996 Lennon-McCartney. 1969. "Carry that Weight" from Abbey Road lp. https://open.spotify.com/track/5eZrW59C3UgBhkqNlowEID?si=cddd237e073047c8 Anderson and Howe. 1973. Close to the Edge from Yessongs lp https://open.spotify.com/track/3xRD4loW61STIKgnxTonYi?si=0772b14d1c61471d
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| Biochemical Mosaic I c.10. Is PE depletion reversed by mTORC1 phosphorylation of LIPIN1 or is DAG authentically activating CCT via membrane association thus obtaining robust PL synthesis? DJGPhD. | 19 Feb 2024 | 00:30:00 | |
References Biochim Biophys Acta. 2011 Jun;1811(6):377-85 Am J Physiol Lung Cell Mol Physiol 2001. 281: L98–L107. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1997. Volume 1348, Issues 1–2, 4 Pages 79-90. Am J Physiol Lung Cell Mol Physiol 2001. Volume 281. Issue 1July Pages L108-L118 JBC 1991. Volume 266, Issue 36, 25 December. Pages 24503-24508 Progress in Lipid Research. 2015. Volume 59, ages 147-171 Nature 2019. volume 575, pages 361–365
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| Biochemical Mosaic I. c.9 Increased inner mitochondrial membrane PE from PS decarboxylase decreases protease mediated degradation of phospholipid transfer proteins thus maintaining fusion potency. | 19 Feb 2024 | 00:30:00 | |
References PLoS Biol 2014. 12(10): e1001969 J Biol Chem. 2012 May18;287(21):17589-17597 J Biol Chem. 2012 Nov 23;287(48):40131-9 Nature 2019. volume 575, pages 361–365
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| Biochemical Mosaic I PA-phosphatase c.8. Membrane fusion and the dynamics of mitochondrial reduction vs. proliferation; the PA phosphatase in lipid metabolism. DJGPhD. 16.2.24 Authentic Biochemistry | 17 Feb 2024 | 00:29:48 | |
References Dr Guerra membrane lectures archive FASEB J. 2021 Jun; 35(6): e21620. Vivaldi, A. 1711. Concerto for 4 Violins in B minor RV 580 https://youtu.be/SY3Kxf7ZTeI?si=JLQXMtK06Y6Yfu_k | |||
| Biochemical Mosaic I. Phosphatidic acid Phosphatase. c.7. Mutational reversal of IDH1 leads to NADPH depletion concomitant with potent anti-PHD enantiomeric 2-hydroxyglutarate obtaining pseudohypoxia. | 16 Feb 2024 | 00:30:00 | |
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| Biochemical Mosaic I. Phosphatidic Acid Phosphatase c.4 GLN utilization and an IMM protease regulate mitochondrial involvement in cancer growth. DJGPhD. Authentic Biochemistry 10Feb24 | 11 Feb 2024 | 00:30:00 | |
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| Biochemical Mosaic Event Ontologies I. Phosphatidic Acid Phosphatase. c.3 Indirect consequences of mitochondrial proteomic variation potentially obtains GLN-linked Warburg glycolysis preventing ROS. | 09 Feb 2024 | 00:29:48 | |
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| Biochemical Mosaic Event Ontologies I. Phosphatidic Acid Phosphatase. Prologomena c.1. | 07 Feb 2024 | 00:30:00 | |
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| Sarcopenia Molecular Pathology. Dr. Daniel J. Guerra. 09Sept24. Authentic Biochemistry Podcast | 10 Sep 2024 | 00:59:02 | |
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| BioMedical Portrait VIII. C.22 CODA. Microglial Leukotrienes in neurodegeneration.DJGPhD.04Feb2024. Authentic Biochemistry Podcast. | 04 Feb 2024 | 00:30:00 | |
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| BioMedical Portrait VIII C.20. Heterologous lipid sequence membrane domains rearrange according to LysoPL polarity after PLA2 mediated 20:4 removal and acetosalicylic acid alters fatty acid ordering. | 01 Feb 2024 | 00:30:00 | |
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