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TitreDateDurée
In updated U.S. autism bill, Congress calls for funding boost, expanded scope10 Sep 202400:05:35

The current Autism CARES Act sunsets in late September.

From reductionism to dynamical systems: How two books influenced my thinking across 30 years of neuroscience29 Aug 202400:04:01

Nicole Rust describes her career-changing literary journey of joy, free will and the evolution of a field.

Reviving 'inside-out' hypothesis of amyloid beta to explain Alzheimer's mysteries17 Jun 202400:08:40

New research is resurfacing old ideas about where the protein forms the disease’s hallmark plaques.

At the credit crossroads: Modern neuroscience needs a cultural shift to adopt new authorship practices10 Jun 202400:09:46

Old heuristics to acknowledge contributors—calling out first and last authors, with everyone else in between—don’t work well for large collaborative and interdisciplinary projects, yet they remain the default.

Should we use the computational or the network approach to analyze functional brain-imaging data-why not both?05 Jun 202400:07:10

Emerging methods make it possible to combine the two tactics from opposite ends of the analytic spectrum, enabling scientists to have their cake and eat it too.

How to explore your scientific values and develop a vision for your field27 May 202400:05:47

As a new professor, I was caught off guard by one part of the job: my role as an evaluator.

Carol Jennings, whose family's genetics informed amyloid cascade hypothesis, dies at 7020 May 202400:03:43

Her advocacy work aided the discovery of a rare inherited form of early-onset Alzheimer’s disease and helped connect affected people with researchers.

How to use race and ethnicity data responsibly in neuroscience research16 May 202400:07:08

Follow these four tips to avoid using the information in problematic ways, including as a proxy for environmental variables.

New look at lampreys rewrites textbooks on origins of sympathetic nervous system06 May 202400:03:49

Sympathetic neurons pepper the embryos of the jawless fish—Earth’s first vertebrates—and overturn the idea that “fight or flight” was an innovation of jawed vertebrates.

NIH seeks input on how structural racism affects brain research, health13 May 202400:07:50

The feedback could lead to “novel ways” to conduct studies and reduce health disparities, a National Institutes of Health employee says.

FDA describes 'objectionable conditions' at New York State Psychiatric Institute18 Apr 202400:06:23

The facility’s institutional review board failed to report a 2021 incident and “serious and ongoing noncompliance” by a principal investigator, according to a letter released by the federal agency this week.

Autism subgroups converge on cell growth pathway05 Dec 202200:04:49

Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.

Neuroscience needs a career path for software engineers20 Aug 202400:07:02

Few institutions have mechanisms for the type of long-term positions that would best benefit the science.

Breaking down the winner's curse: Lessons from brain-wide association studies15 Apr 202400:07:04

We found an issue with a specific type of brain imaging study and tried to share it with the field. Then the backlash began.

Wild and free: Understanding animal behavior beyond the lab11 Apr 202400:08:48

Technological advancements have made it possible to study animals in more natural settings, but researchers are debating what that really means and whether natural is always better.

Knowledge gaps in cephalopod care could stall welfare standards08 Apr 202400:10:26

The U.S. National Institutes of Health wants to regulate research involving cephalopods. But there aren’t enough rigorous studies to base the regulations on, veteran cephalopod researchers say.

Nobel Prize winner Thomas Südhof retracts study04 Apr 202400:03:07

The retraction follows an editorial expression of concern that the journal applied to the paper in October, seven months after it was published in the Proceedings of the National Academy of Sciences.

Newly found hypothalamus circuits shape bullying behaviors in mice01 Apr 202400:06:21

Activity in the tiny brain region helps submissive rodents learn to avoid aggressors, and aggressive mice to curb their attacks, according to two recent studies.

Maiken Nedergaard's power of disruption28 Mar 202400:25:40

The award-winning researcher’s discoveries have changed the way we think about the brain; that’s exactly what her critics dislike.

Expanding 'little brain' may have powered dinosaur flight25 Mar 202400:04:41

The cerebellum swelled in size before flight evolved among modern birds’ dinosaur ancestors, according to a new comparison of fossilized skulls and living birds.

How long-read sequencing will transform neuroscience18 Mar 202400:06:46

New technology that delivers much more than a simple DNA sequence could have a major impact on brain research, enabling researchers to study transcript diversity, imprinting and more.

Making cancer nervous26 Feb 202400:24:40

Nerve cells in the brain and throughout the body can turbocharge tumor growth — a finding that not only expands conventional ideas about the nervous system but points to novel therapeutic targets for a range of malignancies.

'Into the wild': Moving studies of memory and learning out of the lab04 Mar 202400:09:54

People with electrodes embedded deep in their brain are collaborating with a growing posse of plucky researchers to uncover the mysteries of real-world recall.

Nonsense correlations and how to avoid them15 Aug 202400:06:13

This statistical error is common in systems neuroscience. Fortunately, straightforward methods can help you prevent it.

Incentivizing data-sharing in neuroscience: How about a little customer service?11 Mar 202400:07:16

To make data truly reusable, we need to invest in data curators, who help people enter the information into repositories.

Vast diversity of human brain cell types revealed in trove of new datasets31 Oct 202300:06:58

The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.

Journal club: Why do some children lose their autism diagnosis?26 Oct 202300:05:48

More than one-third of a cohort of autistic toddlers no longer meet criteria for the condition at school age, according to a new study, but the findings may not generalize because the cohort is predominantly white and affluent.

Uncertainty and excitement surround one company's cell therapy for epilepsy24 Oct 202300:19:54

After 10 years of work, Neurona may have the data to quiet its skeptics. But its ongoing clinical trial will be the ultimate test.

Mutations in multipurpose gene deal dendrites a double whammy17 Oct 202300:04:46

The mutations disrupt protein translation as well as the cell’s skeleton, according to a new study.

UBE3A's link to synaptic pruning bolstered by fly study12 Oct 202300:05:18

Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.

Debate unfurls over inclusivity and authenticity in research involving minimally verbal autistic people10 Oct 202300:11:44

Autism researchers can’t agree on how far to go to validate the input they gather from minimally verbal autistic people who use certain communication devices.

Common genetic variants shape the structure of the cortex05 Oct 202300:05:38

A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.

Six tips for postdoc success28 Sep 202300:04:28

Postdoctoral positions are relatively short, so starting out on the right foot can make all the difference. Researchers offer their advice for making that happen.

Alterations in circuits characterize six neuropsychiatric conditions26 Sep 202300:04:44

The underlying regional neurobiology of the conditions may differ from person to person.

Is it time to worry about brain chimeras?08 Aug 202400:09:26

Brains made of neurons from two species raise new concerns.

Tablet-based tool to spot autism validated in two studies14 Sep 202300:05:10

The new tool could help clinicians diagnose autism in children younger than 3, the findings show.

Neuronal deafness to stress may add to protein surplus in fragile X12 Sep 202300:03:04

A protective pathway that pauses protein synthesis is muted in a mouse model of fragile X syndrome, according to a new study.

Scammers threaten quality of research survey data05 Sep 202300:10:18

Jammed online surveys and invaded video calls are forcing researchers to rethink their outreach methods.

Social skills decline during adolescence for a sliver of autistic youth07 Sep 202300:04:22

Most children with the condition, however, gain communication and social abilities over time.

Father's genes may drive sociability in male monkeys31 Aug 202300:03:40

The findings in rhesus macaque monkeys may provide clues to sex differences in the heredity of social behavior in people.

Is excess brain fluid an early marker of autism?29 Aug 202300:11:04

Brain scans of hundreds of infants suggest that up to 80 percent of those with autism have unusual amounts of cerebrospinal fluid. Researchers are studying how this might contribute to the condition.

Unwritten rules of tenure24 Aug 202300:03:34

Academics are not always aware of the standards — both explicit and implicit — that are used to assess them for promotion. We explore these expectations and more in this month’s issue of the Spectrum Launch newsletter.

Co-occurring conditions in autistic teens increase with age22 Aug 202300:05:02

The most prevalent conditions include obesity, neurological disorders, anxiety and attention-deficit/hyperactivity disorder.

Autism in Adulthood gets its first impact factor17 Aug 202300:04:16

The 4-year-old journal focuses on research that aims to improve the lives of autistic adults.

Exclusive: Shake-up at top psychiatric institute following suicide in clinical trial15 Aug 202300:05:50

The New York State Psychiatric Institute in New York City is undergoing an audit and a change in leadership following a suicide that occurred during one of its clinical trials.

Martin Giurfa's concept of home01 Aug 202400:15:06

The insect-cognition researcher has done his work across continents, but Argentina is never far from his mind.

Amy Wetherby: Impatient for progress10 Aug 202300:12:42

A speech-language pathologist by training, Wetherby has spent more than four decades developing tools to help identify and treat autism early; now her work has taken on a more personal sense of urgency.

'Gain-of-function' mutation spawns autism traits08 Aug 202300:05:40

The mutation increases the activity of an autism-linked protein and leads to social difficulties and other behavioral differences in mice.

Change of heart and mind: Autism's ties to cardiac defects03 Aug 202300:13:10

Children with congenital heart disease have an increased likelihood of autism. Why?

'A catalyst for change': NIH makes first call for research supporting minimally verbal autistic people01 Aug 202300:06:36

The request is energizing scientists investigating autistic people who largely don’t communicate with spoken words.

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