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Creator: James P. Rathmell, M.D., M.B.A.

November 2024, Volume 141, Issue 5

Overview of November issue original studies.

Transcript

Moderator: BobbieJean Sweitzer, M.D.
Participants: Karim Brohi, M.D. and Richard P. Dutton, M.D., M.B.A.

Articles Discussed:
Correction of Trauma-induced Coagulopathy by Goal-directed Therapy: A Secondary Analysis of the ITACTIC Trial

Tactics versus Strategy in Trauma Resuscitation

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Moderator: James P. Rathmell, M.D.
Participants: Daniele De Luca M.D., Ph.D. and David Tingay, M.B.B.S., Ph.D.

Articles Discussed:
Global and Regional Heterogeneity of Lung Aeration in Neonates with Different Respiratory Disorders: A Physiological, Observational Study

Lung Ultrasound and Regional Heterogeneity: A Bedside Solution to an Under-Recognized Problem?

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Creator: James P. Rathmell, M.D., M.B.A.

October 2024, Volume 141, Issue 4

Overview of October issue original studies.

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Sebastian J. Corlette, M.B.B.S. and Isabelle Constant, Ph.D., M.D.

Articles Discussed:
Changes in the Term Neonatal Electroencephalogram with General Anesthesia – A Systematic Review with Narrative Synthesis

Challenge of Neonatal Anesthesia: Which Optimal EEG Target?

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Lisa M. Einhorn, M.D. and Charles B. Berde, M.D., Ph.D.

Articles Discussed:
Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial

Improving Pain Management After Tonsillectomy

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Creator: James P. Rathmell, M.D., M.B.A.

September 2024, Volume 141, Issue 3

Overview of September issue original studies.

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Moderator: James P. Rathmell, M.D.
Participants: Steven L. Shafer, M.D. and David Clark, M.D., Ph.D.

Articles Discussed:
Safety and Efficacy of Vocacapsaicin for Management of Postsurgical Pain: A Randomized Clinical Trial Sweeping Away Dyspnea

A Spicy New Treatment for Postoperative Pain

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Andrew Bowdle, M.D., Ph.D. and Sorin J. Brull, M.D.

Articles Discussed:
Accuracy and Precision of Three Acceleromyographs, Three Electromyographs and a Mechanomyograph Measuring the Train-of-Four Ratio in the Absence of Neuromuscular Blocking Drugs Vital Sign Data Quality: Not Just a Retrospective Research Problem

Accuracy and Precision of Acceleromyography, Electromyography and Mechanomyography: Time to Re-think What We Know

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Creator: James P. Rathmell, M.D., M.B.A.

August 2024, Volume 141, Issue 2

Overview of August issue original studies.

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Mathias Maleczek, M.D., and Patrick J. McCormick, M.D., M.Eng.

Articles Discussed:
A Comparison of Five Algorithmic Methods and Machine Learning Pattern Recognition for Artifact Detection in Electronic Records of Five Different Vital Signs: A Retrospective Analysis

Vital Sign Data Quality: Not Just a Retrospective Research Problem

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Creator: James P. Rathmell, M.D., M.B.A.

July 2024, Volume 141, Issue 1

Overview of July issue original studies.

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Moderator: James P. Rathmell, M.D.
Participants: Côme Bureau, M.D., Ph.D. and Nikolaos J. Skubas, M.D.

Articles Discussed:
Increasing Sweep Gas Flow Reduces Respiratory Drive and Dyspnea in Nonintubated Venoarterial Extracorporeal Membrane Oxygenation Patients: A Pilot Study

Sweeping Away Dyspnea

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Aurora N. Quaye, M.D. and Douglas A. Colquhoun, M.B.Ch.B., M.Sc., M.P.H.

Articles Discussed:
Association between Colonoscopy Sedation Type and Polyp Detection: A Registry-based Cohort Study

 Does Propofol Improve Polyp Detection during Colonoscopy? The Promise and Peril of Clinical Registry Data

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Moderator: James P. Rathmell, M.D.
Participants: Albert Dahan, M.D., Ph.D., and Thomas K. Henthorn, M.D.

Articles Discussed:
Reversal of Propofol-induced Depression of the Hypoxic Ventilatory Response by BK-channel Blocker ENA-001: A Randomized Controlled Trial

Reversal for Respiratory Depression: Let’s Take a Breath!

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Creator: James P. Rathmell, M.D., M.B.A.

June 2024, Volume 140, Issue 6

Overview of June issue original studies.

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Jessica C. Martin, Ph.D., B.Sc. and Jerry Chao, M.D., M.Sc.

Articles Discussed:
The Topographical Features of Pediatric Electroencephalography during High Initial Concentration Sevoflurane for Inhalational Induction of Anesthesia

A Window into the Developing Brain: Toward a Deeper Understanding of Pediatric Anesthesia

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Creator: James P. Rathmell, M.D., M.B.A.

May 2024, Volume 140, Issue 5

Overview of May issue original studies.

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Moderator: James P. Rathmell, M.D.
Participants: Faraj Abdallah, M.D. and Michael R. Fettiplace, M.D., Ph.D. and Ashraf S. Habib, M.D., M.B.B.Ch., M.Sc., M.H.Sc. and Jonathan Slonin, M.D., M.B.A.

Articles Discussed:
Analgesic Effectiveness of Liposomal Bupivacaine versus Plain Local Anesthetics for Abdominal Fascial Plane Blocks: A Systematic Review and Meta-analysis of Randomized Trials

Meta-analyses of Randomized Clinical Trials in Postsurgical Pain: Verify before Trusting

Liposomal Bupivacaine for Abdominal Fascial Plane Blocks: No Evidence or Lack of Relevant Evidence?

Liposomal Bupivacaine, Scientific Evidence, and the Clinician’s Conundrum

 Liposomal Bupivacaine’s Plausibility Fails to Translate

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Creator: James P. Rathmell, M.D., M.B.A.

April 2024, Volume 140, Issue 4

Overview of April issue original studies.

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Maximilian Sebastian Schaefer, M.D. and Amy Gaskell, M.B.Ch.B., Ph.D.

Articles Discussed:
Intraoperative Use of Phenylephrine versus Ephedrine and Postoperative Delirium: A Multicenter Retrospective Cohort Study

Caveat Emptor: Vasopressor Choice and Postoperative Delirium—A Complex Relationship Explored

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Moderator: James P. Rathmell, M.D.
Participants: Anahi Perlas, M.D. and Mark Warner, M.D.

Articles Discussed:
Baseline Gastric Volume in Fasting Diabetic Patients Is Not Higher than That in Nondiabetic Patients: A Cross-sectional Noninferiority Study

Diabetic Patients, Assessment of Preoperative Gastric Contents, and Potential Reduction of Risk of Pulmonary Aspiration

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Pavel S. Roshanov, M.D., M.Sc.

Articles Discussed:
One-Year Outcomes After Discharge from Noncardiac Surgery and Association Between Pre-Discharge Complications and Death After Discharge: Analysis of the VISION Prospective Cohort Study

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Scott Segal, M.D., M.H.C.M. and Jeffrey B. Cooper, Ph.D.

Articles Discussed:
A Quality Improvement Initiative to Reduce Adverse Effects of Transitions of Anesthesia Care on Postoperative Outcomes: A Retrospective Cohort Study

Anesthesia Needs to Lead the Way in Safety—Again—through the Universal Adoption of Structured Handoffs

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Moderator: James P. Rathmell, M.D.
Participants: Mark D. Neuman, M.D., M.Sc. and Elizabeth L. Whitlock, M.D., M.Sc.

Articles Discussed:
Long-term Outcomes with Spinal versus General Anesthesia for Hip Fracture Surgery: A Randomized Trial

REGAINing the Freedom to Choose Insensibility for Hip Fracture Surgery

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Creator: James P. Rathmell, M.D., M.B.A.

March 2024, Volume 140, Issue 3

Overview of March issue original studies.

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Creator: James P. Rathmell, M.D., M.B.A.

February 2024, Volume 140, Issue 2

Overview of February issue original studies.

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Moderator: James P. Rathmell, M.D.
Participants: Mattia Busana, M.D. and Marcos F. Vidal Melo, M.D., Ph.D.

Articles Discussed:
The Causes of Hypoxemia of COVID-19 ARDS: A Combined MIGET and Dual-Energy CT Study

Structure–Function Relationships Determining Hypoxemia in COVID-19 Acute Respiratory Distress Syndrome

Moderator: BobbieJean Sweitzer, M.D.
Participants: Michael F. Aziz, M.D. and Paul S. Myles, M.B., B.S., M.P.H., M.D., D.Sc.

Articles Discussed:
Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study

COVID-19 and Surgery: Getting Back to Business

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Moderator: James P. Rathmell, M.D.
Participants: Thomas Langer, M.D. and David A. Story, M.B.B.S., B.Med.Sci., M.D.

Articles Discussed:
Combining the Physical-Chemical Approach with Standard Base Excess to Understand the Compensation of Respiratory Acid-Base Derangements: An Individual Participant Meta-Analysis Approach to Data from Multiple Canine and Human Experiments

Respiratory Changes and Acid–Base Compensation: Watch the Salt

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Creator: James P. Rathmell, M.D.

January 2024, Volume 140, Issue 1

Overview of January issue original studies.

Transcript

Moderator: BobbieJean Sweitzer, M.D.
Participants: Jean Guglielminotti, M.D., Ph.D.

Articles Discussed:
Association of Labor Neuraxial Analgesia with Maternal Blood Transfusion

Transcript

Creator: James P. Rathmell, M.D., M.B.A.

December 2023, Volume 139, Issue 6

Overview of December issue original studies.

Transcript

Moderator: James P. Rathmell, M.D.
Participants: Stephan Frangakis, M.D., Ph.D. and Carolina B. Meloto, D.D.S., Ph.D.

Articles Discussed:
Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses

Genetics of Postsurgical Pain: Where Do We Go from Here?

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Moderator: James P. Rathmell, M.D.
Participants: Phillip Vlisides, M.D. and Patrick L. Purdon, Ph.D.

Articles Discussed:
Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Non-Cardiac Surgical Patients: a Prospective Cohort Study

Charting a Cognitive Course: Can Electroencephalographic or Oximetry Biomarkers Predict Postoperative Cognitive Function?

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Anjali A. Dixit, M.D., M.P.H. and Avery Tung, M.D.

Articles Discussed:
Association Between “Balance Billing” Legislation and Anesthesia Payments in California: A Retrospective Analysis

Balanced Billing Legislation and the Invisible Hand of Adam Smith

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Creator: James P. Rathmell, M.D., M.B.A.

November 2023, Volume 139, Issue 5

Overview of November issue original studies.

Transcript

Moderator: BobbieJean Sweitzer, M.D.
Participants: Evan D. Kharasch, M.D., Ph.D., and Paul S. Myles, M.B., B.S., M.P.H., M.D., D.Sc., F.C.A.I., F.A.N.Z.C.A., F.A.H.M.S.

Articles Discussed:
Intraoperative Methadone in Next-day Discharge Outpatient Surgery: A Randomized, Double-blinded, Dose-finding Pilot Study

Consideration of Methadone as an Analgesic Option for Short-stay Surgery

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Moderator: James P. Rathmell, M.D.
Participants: Allan F. Simpao, M.D., M.B.I., and Caleb Ing, M.D., M.S.

Articles Discussed:
Anesthesia and Sedation Exposure and Neurodevelopmental Outcomes in Infants Undergoing Congenital Cardiac Surgery: A Retrospective Cohort Study

Developmental Anesthesia Neurotoxicity: Lessons from the Heart

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Creator: James P. Rathmell, M.D., M.B.A.

October 2023, Volume 139, Issue 4

Overview of October issue original studies.

Transcript

Moderator: James Rathmell, M.D.
Participants: Joerg Krebs, M.D. and Hermann Wrigge, M.D., Ph.D.

Articles Discussed:
Individualized Positive End-Expiratory Pressure Titration Strategies in Superobese Patients Undergoing Laparoscopic Surgery: Prospective and Non-Randomized Crossover Study

Pressure for High PEEP in Obese Surgical Patients is Growing

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Alexandre Mansour, M.D., Ph.D.

Articles Discussed:
Combined Platelet and Red Blood Cell Recovery During On-Pump Cardiac Surgery Using Same™ By I-SEP Autotransfusion Device: A First-In-Human Non-Comparative Study (I-TRANSEP Study)

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Creator: James P. Rathmell, M.D.

September 2023, Volume 139, Issue 3

Overview of September issue original studies.

Transcript

Moderator: BobbieJean Sweitzer, M.D.
Participants: Daniel I. McIsaac, M.D., M.P.H.

Articles Discussed:
Attributable Perioperative Cost of Frailty After Major, Elective Non-cardiac Surgery: A Population-based Cohort Study

Transcript

Moderator: James Rathmell, M.D.
Participants: Karsten Bartels, M.D., Ph.D., M.B.A. and Chad Michael Brummett, M.D.

Articles Discussed:
Best Practice Alerts Informed by Inpatient Opioid Intake to Reduce Opioid Prescribing after Surgery (PRIOR): A Cluster Randomized Multiple Crossover Trial

Best Practice Alerts: A Poke in the Eye or an Efficient Method for Safer Prescribing?

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Creator: James P. Rathmell, M.D.

August 2023, Volume 139, Issue 2

Overview of August issue original studies.

Transcript

Moderator: BobbieJean Sweitzer, M.D.
Participants: Robert S. White, M.D., M.S. and Warren S. Sandberg, M.D., Ph.D.

Articles Discussed:
Antiemetic Administration and its Association with Race: A Retrospective Cohort Study Association Multicenter Study

“People, We Have a Problem”

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Moderator: BobbieJean Sweitzer, M.D.
Participants: Konrad Meissner, M.D.

Articles Discussed:
Morphine and Hydromorphone Effects, Side Effects and Variability – a Crossover Study in Human Volunteers

Transcript

Moderator: James Rathmell, M.D.
Participants: Andrew Bowdle, M.D., Ph.D. and Michael M. Todd, M.D.

Articles Discussed:
A Dose-Finding Study of Sugammadex for Reversal of Rocuronium in Cardiac Surgery Patients and Postoperative Monitoring for Recurrent Paralysis

Sugammadex is Not a Silver Bullet: Caveats Regarding Unmonitored Reversal

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Creator: James P. Rathmell, M.D.

July 2023, Volume 139, Issue 1

Overview of July issue original studies.

Transcript